Reference urinary LTE4 levels in normal individuals: A pilot study

European Annals of Allergy and Clinical Immunology

Volumn 43, Issue 1, 2011, Pages 22-28

  Dal Negro, R W ^a   Visconti, M ^a   Micheletto, C ^a   Tognella, S ^a   Guerriero, M ^b  

^a Ospedale   (Italy)

^b UNIVERSITY OF VERONA   (Italy)

Author keywords

Normal individuals; Reference values; Urine LTE4

Indexed keywords

LEUKOTRIENE E4;

ADOLESCENT; ADULT; AGE; AGED; ANALYSIS OF VARIANCE; ARTICLE; CHILD; ENZYME IMMUNOASSAY; FEMALE; GENDER; HUMAN; INFANT; LINEAR REGRESSION ANALYSIS; MALE; PILOT STUDY; PRESCHOOL CHILD; REFERENCE VALUE; SCHOOL CHILD; STUDENT T TEST; URINE; URINE LEVEL; MIDDLE AGED;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; LEUKOTRIENE E4; MALE; MIDDLE AGED; PILOT PROJECTS; REFERENCE VALUES;

EID: 79951747034     PISSN: 03979148     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Werz O, Steinhilber D. Therapeutic options for 5-lipoxygenase inhibitors. Pharmacol Ther 2006; 112: 701-18. (Pubitemid 44592614)
2. Ford-Hutchionson A, Greser M, Young R. 5-Lipoxygenase. Ann Rev Biochem 1994; 63: 383-417. (Pubitemid 24218638)
3. Austen KF, Maekawa A, Kanaoka Y, Boyce JA. The leukotriene E4 puzzle: finding the missing pieces and revealing the pathobio-logic implications. J Allergy Clin Immunol 2009; 124: 406-14.
4. Kumlin M. How to measure leukotrienes in man. In Rodger I, Botting J, Dahlen S-E Editors, Leukotriens. Kluwer Academic Publisher 1998: 43-54.
5. Kumlin M, Dahlen S-E. Characteristics of formation and further metabolism of leukotrienes in the chopped human lung. Biochem Biphys Acta 1990; 1044: 201-10. (Pubitemid 20151275)
6. Granstrom E, Kumlin M, Kindahl H. Radioimmunoassay of eicosanoids. In: Benedetto C, McDonald-Gibson RG, Nigam S, Slater TF, (editors). Prostaglandins and related substances: a pratical approach. Oxford: IRL Press, 1987: 167-95.
7. Westcott JY, Johnston K, Batt RA, Wenzel SE, Voelkel NF. Measurement of peptidoleukotrienes in biological fluids. J Appl Physiol 1990; 68: 2640-8. (Pubitemid 20212662)
8. Tagari P, Ethier D, Carry M. Measurements of urinary leukotrienes by reversephase liquid chromatography and radioimmunoassay. Clin Chem 1989; 35: 388-91. (Pubitemid 19086685)
9. Kumlin M, Dahlen B, Bjorck T, Zetterstrom O, Granstrom E, Dahlen S-E. Urinary excretion of leukotriene E4 and 11-dehy-dro-thromboxane B2 in respinse to bronchial provocations with allergen, aspirin, leukotriene D4 and histamine in asthmatics. Am Rev Resp Dis 1992; 146: 96-103.
10. Drazen JM, O'Brien J, Sparrow D. Recovery of leukotriene E4 from the urine of patients with airway obstruction. Am Rev Resp Dis 1992; 146: 104-8.
11. Sladek K, Dworski R, Fitgerald GA. Allergen-stimulated release of thromboxane A2 and leukotriene E4 in humans. Am Rev Resp Dis 1990; 141: 1441-5.
12. Pradelles P, Grassi J, Maclouf JA. Enzyme immunoassays of eco-sanoids using acetylcholinesterase as label : an alternative to ra-dioimmunoassay. Anal Chem 1985; 57, 1170-3.
13. Brujinzeel PL, Virchow JC, Rihs S. Lack of increased numbers of low-density eosinophils in the circulation of asthmatic individuals. Clin Exp Allergy 1993; 23: 261-96.
14. Koshino T, Takno S, Houjo T. Expression of 5-lypoxygenase and 5-lypoxigenase-activating protein mRNA in the peripheral blood leukocytes in asthmatics. Biochem Biophys Res Commun 1998; 27: 510-3. (Pubitemid 28420857)
15. Manning PJ, Rokach J, Malo JL, Ethier D, Cartier A, Girard Y., Urinary leukotriene E4 levels during early and late asthmatic response. J Allergy Clin Immunol 1990; 86: 211-20. (Pubitemid 20288726)
16. Higashi N, Taniguchi M, Mita H, et al. Clinical features of asthmatic patients with increased urinary leukotriene E4 exctretion: involvement of chronic hyperplastic rhinosinusitis with nasal polyposis. J Allergy Clin Immunol 2004; 113; 277-83. (Pubitemid 38210550)
17. Micheletto C, Visconti M, Tognella S, Facchini FM, Dal Negro RW. Aspirin induced asthma (AIA) with nasal polyps has the highest basal LTE4 excretion: a study vs AIA without polyps, mild atopic asthma, and normal controls. Eur Ann Allergy Clin Immunol 2006; 38, 20-3. (Pubitemid 43226939)
18. Stevenson DD, Szczeklik A. Clinical and pathologic perspectives on aspirin sensitivity and asthma. J Allergy Clin Immunol 2006; 118: 773-86. (Pubitemid 44515109)
19. Micheletto C, Tognella S, Visconti M, Trevisan F, Dal Negro RW. Changes in urinary LTE4 and nasal functions following nasal provocation test with ASA in ASAtolerant and - intolerant asthmatics. Resp Med 2006; 100, 2144-50. (Pubitemid 44718396)
20. Micheletto C, Visconti M, Tognella S, Trevisan F, Dal Negro RW. Urinary LTE4 is higher after nasal provocation test with LASA in bronchial than in only nasal responders. Eur Ann Allergy Clin Immunol 2007; 39 (5): 162-6. (Pubitemid 46954543)
21. Micheletto C, Visconti M, Trevisan F, Tornella S, Bertacco S, Dal Negro RW. The prevalence of nasal polyps and the corresponding urinary LTE4 levels in severe compared to mild and moderate asthma. Eur Ann Allergy Clin Immunol 2010; 42 (3): 120-4.
22. Klotsman M, York T, Pillai SG, et al. Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast. Pharmacogenet Genomics 2007; 17: 189-96. (Pubitemid 46668003)