메뉴 건너뛰기




Volumn 269, Issue 3, 2011, Pages 322-332

Associations between interleukin-1 (IL-1) gene variations or IL-1 receptor antagonist levels and the development of type 2 diabetes

Author keywords

Diabetes; Epidemiology; IL 1 genes; Inflammation; Interleukin 1 receptor antagonist

Indexed keywords

ANTIDIABETIC AGENT; BIOLOGICAL MARKER; C REACTIVE PROTEIN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA;

EID: 79951711058     PISSN: 09546820     EISSN: 13652796     Source Type: Journal    
DOI: 10.1111/j.1365-2796.2010.02294.x     Document Type: Article
Times cited : (52)

References (27)
  • 1
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature 2006; 444: 860-7.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 2
    • 21344460247 scopus 로고    scopus 로고
    • An immune origin of type 2 diabetes?
    • Kolb H, Mandrup-Poulsen T. An immune origin of type 2 diabetes? Diabetologia 2005; 48: 1038-50.
    • (2005) Diabetologia , vol.48 , pp. 1038-1050
    • Kolb, H.1    Mandrup-Poulsen, T.2
  • 3
    • 1442275317 scopus 로고    scopus 로고
    • Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes
    • Pickup JC. Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes. Diabetes Care 2004; 27: 813-23.
    • (2004) Diabetes Care , vol.27 , pp. 813-823
    • Pickup, J.C.1
  • 4
    • 62649139025 scopus 로고    scopus 로고
    • Immunological and inflammatory functions of the interleukin-1 family
    • Dinarello CA. Immunological and inflammatory functions of the interleukin-1 family. Annu Rev Immunol 2009; 27: 519-50.
    • (2009) Annu Rev Immunol , vol.27 , pp. 519-550
    • Dinarello, C.A.1
  • 6
    • 77951831569 scopus 로고    scopus 로고
    • Accelerated increase in serum interleukin-1 receptor antagonist starts 6years before diagnosis of type 2 diabetes: Whitehall II prospective cohort study
    • Carstensen M, Herder C, Kivimaki M et al. Accelerated increase in serum interleukin-1 receptor antagonist starts 6years before diagnosis of type 2 diabetes: Whitehall II prospective cohort study. Diabetes 2010; 59: 1222-7.
    • (2010) Diabetes , vol.59 , pp. 1222-1227
    • Carstensen, M.1    Herder, C.2    Kivimaki, M.3
  • 7
    • 34250025351 scopus 로고    scopus 로고
    • Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels
    • Rafiq S, Stevens K, Hurst AJ et al. Common genetic variation in the gene encoding interleukin-1-receptor antagonist (IL-1RA) is associated with altered circulating IL-1RA levels. Genes Immun 2007; 8: 344-51.
    • (2007) Genes Immun , vol.8 , pp. 344-351
    • Rafiq, S.1    Stevens, K.2    Hurst, A.J.3
  • 8
    • 44949201115 scopus 로고    scopus 로고
    • A genome-wide association study identifies protein quantitative trait loci (pQTLs)
    • e1000072.
    • Melzer D, Perry JR, Hernandez D et al. A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet 2008; 4: e1000072.
    • (2008) PLoS Genet , vol.4
    • Melzer, D.1    Perry, J.R.2    Hernandez, D.3
  • 9
    • 45049083638 scopus 로고    scopus 로고
    • Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation
    • Reiner AP, Wurfel MM, Lange LA et al. Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation. Arterioscler Thromb Vasc Biol 2008; 28: 1407-12.
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1407-1412
    • Reiner, A.P.1    Wurfel, M.M.2    Lange, L.A.3
  • 10
    • 70449125796 scopus 로고    scopus 로고
    • Association of variation in the interleukin-1 gene family with diabetes and glucose homeostasis
    • Luotola K, Paakkonen R, Alanne M et al. Association of variation in the interleukin-1 gene family with diabetes and glucose homeostasis. J Clin Endocrinol Metab 2009; 94: 4575-83.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4575-4583
    • Luotola, K.1    Paakkonen, R.2    Alanne, M.3
  • 11
    • 77956978000 scopus 로고    scopus 로고
    • Genetic variation of the interleukin-1 family and nongenetic factors determining the interleukin-1 receptor antagonist phenotypes
    • Luotola K, Pietila A, Alanne M et al. Genetic variation of the interleukin-1 family and nongenetic factors determining the interleukin-1 receptor antagonist phenotypes. Metabolism 2010; 59: 1520-7.
    • (2010) Metabolism , vol.59 , pp. 1520-1527
    • Luotola, K.1    Pietila, A.2    Alanne, M.3
  • 13
    • 0004012386 scopus 로고    scopus 로고
    • Health and Functional Capacity in Finland. Baseline Results of the Health 2000 Health Examination Survey
    • Helsinki: Publications of the National Public Health Institute, B12.
    • Aromaa A, Koskinen S. Health and Functional Capacity in Finland. Baseline Results of the Health 2000 Health Examination Survey. Helsinki: Publications of the National Public Health Institute, 2004; B12.
    • (2004)
    • Aromaa, A.1    Koskinen, S.2
  • 14
    • 77952721703 scopus 로고    scopus 로고
    • Thirty-five-year trends in cardiovascular risk factors in Finland
    • Vartiainen E, Laatikainen T, Peltonen M et al. Thirty-five-year trends in cardiovascular risk factors in Finland. Int J Epidemiol 2010; 39: 504-18.
    • (2010) Int J Epidemiol , vol.39 , pp. 504-518
    • Vartiainen, E.1    Laatikainen, T.2    Peltonen, M.3
  • 15
    • 0003725206 scopus 로고    scopus 로고
    • Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications: Report of a WHO Consultation. Part 1: Diagnosis and Classification of Diabetes Mellitus
    • World Health Organization. Geneva: World Health Organization.
    • World Health Organization. Definition, Diagnosis and Classification of Diabetes Mellitus and its Complications: Report of a WHO Consultation. Part 1: Diagnosis and Classification of Diabetes Mellitus. Geneva: World Health Organization, 1999.
    • (1999)
  • 16
    • 1842334456 scopus 로고    scopus 로고
    • Report of the expert committee on the diagnosis and classification of diabetes mellitus
    • Expert Committee on the Diagnosis and Classification of Diabetes Mellitus.
    • Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 1997; 20: 1183-97.
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 17
    • 79951686097 scopus 로고    scopus 로고
    • International Diabetes Federation. The IDF consensus worldwide definition of the metabolic syndrome. Available from: [accessed on 26 April 2010].
    • International Diabetes Federation. The IDF consensus worldwide definition of the metabolic syndrome. Available from: [accessed on 26 April 2010].
  • 18
    • 13444269543 scopus 로고    scopus 로고
    • Haploview: analysis and visualization of LD and haplotype maps
    • Barrett JC, Fry B, Maller J, Daly MJ. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005; 21: 263-5.
    • (2005) Bioinformatics , vol.21 , pp. 263-265
    • Barrett, J.C.1    Fry, B.2    Maller, J.3    Daly, M.J.4
  • 19
    • 18444369013 scopus 로고    scopus 로고
    • The structure of haplotype blocks in the human genome
    • Gabriel SB, Schaffner SF, Nguyen H et al. The structure of haplotype blocks in the human genome. Science 2002; 296: 2225-9.
    • (2002) Science , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1    Schaffner, S.F.2    Nguyen, H.3
  • 20
    • 0242691208 scopus 로고    scopus 로고
    • A comparison of bayesian methods for haplotype reconstruction from population genotype data
    • Stephens M, Donnelly P. A comparison of bayesian methods for haplotype reconstruction from population genotype data. Am J Hum Genet 2003; 73: 1162-9.
    • (2003) Am J Hum Genet , vol.73 , pp. 1162-1169
    • Stephens, M.1    Donnelly, P.2
  • 21
    • 0036896760 scopus 로고    scopus 로고
    • Interleukin-1 receptor antagonist genotype is associated with coronary atherosclerosis in patients with type 2 diabetes
    • Marculescu R, Endler G, Schillinger M et al. Interleukin-1 receptor antagonist genotype is associated with coronary atherosclerosis in patients with type 2 diabetes. Diabetes 2002; 51: 3582-5.
    • (2002) Diabetes , vol.51 , pp. 3582-3585
    • Marculescu, R.1    Endler, G.2    Schillinger, M.3
  • 22
    • 33845499326 scopus 로고    scopus 로고
    • Changes in inflammatory cytokines are related to impaired glucose tolerance in offspring of type 2 diabetic subjects
    • Ruotsalainen E, Salmenniemi U, Vauhkonen I et al. Changes in inflammatory cytokines are related to impaired glucose tolerance in offspring of type 2 diabetic subjects. Diabetes Care 2006; 29: 2714-20.
    • (2006) Diabetes Care , vol.29 , pp. 2714-2720
    • Ruotsalainen, E.1    Salmenniemi, U.2    Vauhkonen, I.3
  • 23
    • 2542541353 scopus 로고    scopus 로고
    • Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets
    • Maedler K, Sergeev P, Ehses JA et al. Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets. Proc Natl Acad Sci U S A 2004; 101: 8138-43.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 8138-8143
    • Maedler, K.1    Sergeev, P.2    Ehses, J.A.3
  • 24
    • 64749095071 scopus 로고    scopus 로고
    • Elevated levels of the anti-inflammatory interleukin-1 receptor antagonist precede the onset of type 2 diabetes: the Whitehall II study
    • Herder C, Brunner EJ, Rathmann W et al. Elevated levels of the anti-inflammatory interleukin-1 receptor antagonist precede the onset of type 2 diabetes: the Whitehall II study. Diabetes Care 2009; 32: 421-3.
    • (2009) Diabetes Care , vol.32 , pp. 421-423
    • Herder, C.1    Brunner, E.J.2    Rathmann, W.3
  • 25
    • 77956336714 scopus 로고    scopus 로고
    • Thirty-one novel biomarkers as predictors for clinically incident diabetes
    • e10100.
    • Salomaa V, Havulinna A, Saarela O et al. Thirty-one novel biomarkers as predictors for clinically incident diabetes. PLoS ONE 2010; 5: e10100.
    • (2010) PLoS ONE , vol.5
    • Salomaa, V.1    Havulinna, A.2    Saarela, O.3
  • 26
    • 53049108337 scopus 로고    scopus 로고
    • Metabolic syndrome and incident diabetes: current state of the evidence
    • Ford ES, Li C, Sattar N. Metabolic syndrome and incident diabetes: current state of the evidence. Diabetes Care 2008; 31: 1898-904.
    • (2008) Diabetes Care , vol.31 , pp. 1898-1904
    • Ford, E.S.1    Li, C.2    Sattar, N.3
  • 27
    • 34147109919 scopus 로고    scopus 로고
    • Sex differences in the prediction of type 2 diabetes by inflammatory markers: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002
    • Thorand B, Baumert J, Kolb H et al. Sex differences in the prediction of type 2 diabetes by inflammatory markers: results from the MONICA/KORA Augsburg case-cohort study, 1984-2002. Diabetes Care 2007; 30: 854-60.
    • (2007) Diabetes Care , vol.30 , pp. 854-860
    • Thorand, B.1    Baumert, J.2    Kolb, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.