Low peripheral nerve conduction velocities and amplitudes are strongly related to diabetic microvascular complications in type 1 diabetes: The EURODIAB prospective complications study

Diabetes Care

Volumn 33, Issue 12, 2010, Pages 2648-2653

  Charles, Morten ^a   Soedamah Muthu, Sabita S ^b   Tesfaye, Solomon ^c   Fuller, John H ^d   Arezzo, Joseph C ^e   Chaturvedi, Nishi ^f   Witte, Daniel R ^g  

^a AARHUS UNIVERSITY   (Denmark)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c UNIVERSITY OF SHEFFIELD   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

^g STENO DIABETES CENTER   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; DISEASE DURATION; FEMALE; FOLLOW UP; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; MULTIVARIATE ANALYSIS; NERVE CONDUCTION; PERIPHERAL NERVE; PERIPHERAL NEUROPATHY; PERONEUS NERVE; PROSPECTIVE STUDY; ULNAR NERVE;

ADULT; DIABETES MELLITUS, TYPE 1; DIABETIC NEUROPATHIES; DIABETIC RETINOPATHY; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; MALE; NEURAL CONDUCTION; PERIPHERAL NERVES; YOUNG ADULT;

EID: 79951689097     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc10-0456     Document Type: Article

References (25)

1. Dyck PJ, Kratz KM, Karnes JL, Litchy WJ, Klein R, Pach JM, Wilson DM, O'Brien PC, Melton LJ 3rd, Service FJ. The prevalence by staged severity of various types of diabetic neuropathy, retinopathy, and nephropathy in a population-based cohort: the Rochester Diabetic Neuropathy Study. Neurology 1993;43:817-824 (Pubitemid 23121981)
2. Ziegler D, Rathmann W, Dickhaus T, Meisinger C, Mielck A. Prevalence of polyneuropathy in pre-diabetes and diabetes is associated with abdominal obesity and macroangiopathy: the MONICA/KORA Augsburg Surveys S2 and S3. Diabetes Care 2008;31:464-469
3. The effect of intensive diabetes therapy on the development and progression of neuropathy. The Diabetes Control and Complications Trial Research Group. Ann Intern Med 1995;122:561-568
4. Stratton IM, Holman RR, Boulton AJ. Risk factors for neuropathy in UKPDS (Abstract). Diabetologia 2004;47(Suppl. 1): A47
5. England JD, Gronseth GS, Franklin G, Miller RG, Asbury AK, Carter GT, Cohen JA, Fisher MA, Howard JF, Kinsella LJ, Latov N, Lewis RA, Low PA, Sumner AJ. Distal symmetric polyneuropathy: a definition for clinical research: report of the American Academy of Neurology, the American Association of Electrodiagnostic Medicine, and the American Academy of Physical Medicine and Rehabilitation. Neurology 2005;64:199-207
6. Dyck PJ, O'Brien PC, Litchy WJ, Harper CM, Klein CJ, Dyck PJ. Monotonicity of nerve tests in diabetes: subclinical nerve dysfunction precedes diagnosis of polyneuropathy. Diabetes Care 2005;28: 2192-2200 (Pubitemid 41242467)
7. Stetson DS, Albers JW, Silverstein BA, Wolfe RA. Effects of age, sex, and anthropometric factors on nerve conduction measures. Muscle Nerve 1992;15:1095-1104
8. Effect of intensive diabetes treatment on nerve conduction in the Diabetes Control and Complications Trial. Ann Neurol 1995;38:869-880
9. Tesfaye S, Chaturvedi N, Eaton SE, Ward JD, Manes C, Ionescu-Tirgoviste C, Witte DR, Fuller JH, EURODIAB Prospective Complications Study Group. Vascular risk factors and diabetic neuropathy. N Engl J Med 2005;352:341-350
10. Microvascular and acute complications in IDDM patients: the EURODIAB IDDM Complications Study. Diabetologia 1994; 37:278-285
11. Chaturvedi N, Sjoelie AK, Porta M, Aldington SJ, Fuller JH, Songini M, Kohner EM, EURODIAB Prospective Complications Study. Markers of insulin resistance are strong risk factors for retinopathy incidence in type 1 diabetes. Diabetes Care 2001;24:284-289
12. Tesfaye S, Stevens LK, Stephenson JM, Fuller JH, Plater M, Ionescu-Tirgoviste C, Nuber A, Pozza G, Ward JD. Prevalence of diabetic peripheral neuropathy and its relation to glycaemic control and potential risk factors: the EURODIAB IDDM Complications Study. Diabetologia 1996;39: 1377-1384 (Pubitemid 26356070)
13. Falck B, Staalberg E, Bischoff C. Sensory nerve conduction studies with surface electrodes. Methods Clin Neurophysiol 1994;5:1-20
14. Staalberg E, Falck B. Clinical motor nerve conduction studies. Methods Clin Neurophysiol 1993;4:61-80
15. Albers JW, Herman WH, Pop-Busui R, Martin CL, Cleary P, Waberski B, Diabetes Control and Complications Trial (DCCT)/Epidemiology of Diabetes Intervention and Complications (EDIC) Research Group. Subclinical neuropathy among Diabetes Control and Complications Trial participants without diagnosable neuropathy at trial completion: possible predictors of incident neuropathy? Diabetes Care 2007;30:2613-2618
16. Albers JW, Brown MB, Sima AA, Greene DA. Nerve conduction measures in mild diabetic neuropathy in the Early Diabetes Intervention Trial: the effects of age, sex, type of diabetes, disease duration, and anthropometric factors. Tolrestat Study Group for the Early Diabetes Intervention Trial. Neurology 1996;46:85-91 (Pubitemid 26156107)
17. Tkac I, Bril V. Glycemic control is related to the electrophysiologic severity of diabetic peripheral sensorimotor polyneuropathy. Diabetes Care 1998;21:1749-1752 (Pubitemid 28449819)
18. Valensi P, Giroux C, Seeboth-Ghalayini B, Attali JR. Diabetic peripheral neuropathy: effects of age, duration of diabetes, glycemic control, and vascular factors. J Diabetes Complications 1997;11:27-34 (Pubitemid 27077766)
19. Jarmuzewska EA, Ghidoni A, Mangoni AA. Hypertension and sensorimotor peripheral neuropathy in type 2 diabetes. Eur Neurol 2007;57:91-95
20. Huang CC, Chen TW, Weng MC, Lee CL, Tseng HC, Huang MH. Effect of glycemic control on electrophysiologic changes of diabetic neuropathy in type 2 diabetic patients. Kaohsiung J Med Sci 2005; 21:15-21
21. Wiggin TD, Sullivan KA, Pop-Busui R, Amato A, Sima AA, Feldman EL. Elevated triglycerides correlate with progression of diabetic neuropathy. Diabetes 2009;58: 1634-1640
22. Reichard P, Pihl M, Rosenqvist U, Sule J. Complications in IDDM are caused by elevated blood glucose level: the Stockholm Diabetes Intervention Study (SDIS) at 10-year follow up. Diabetologia 1996; 39:1483-1488 (Pubitemid 26397354)
23. Cameron NE, Eaton SE, Cotter MA, Tesfaye S. Vascular factors and metabolic interactions in the pathogenesis of diabetic neuropathy. Diabetologia 2001;44:1973-1988 (Pubitemid 33124042)
24. Dyck PJ, Davies JL, Clark VM, Litchy WJ, Dyck PJ, Klein CJ, Rizza RA, Pach JM, Klein R, Larson TS, Melton LJ 3rd, O'Brien PC. Modeling chronic glycemic exposure variables as correlates and predictors of microvascular complications of diabetes. Diabetes Care 2006;29:2282-2288 (Pubitemid 44899866)
25. Dyck PJ, Norell JE, Tritschler H, Schuette K, Samigullin R, Ziegler D, Bastyr EJ 3rd, Litchy WJ, O'Brien PC. Challenges in design of multicenter trials: end points assessed longitudinally for change and monotonicity. Diabetes Care 2007;30: 2619-2625 (Pubitemid 47547807)