Effect of timing of chronic preoperative aspirin discontinuation on morbidity and mortality in coronary artery bypass surgery

Circulation

Volumn 123, Issue 6, 2011, Pages 577-583

  Jacob, Miriam ^a   Smedira, Nicholas ^a   Blackstone, Eugene ^a   Williams, Sarah ^a   Cho, Leslie ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

arteriosclerosis; aspirin; bypass; coronary disease; surgery

Indexed keywords

ACETYLSALICYLIC ACID;

AGED; ARTICLE; BLOOD TRANSFUSION; CORONARY ARTERY BYPASS GRAFT; DATA BASE; DISEASE ASSOCIATION; DRUG EFFECT; DRUG WITHDRAWAL; FEMALE; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MORTALITY; OUTCOME ASSESSMENT; POSTOPERATIVE HEMORRHAGE; PREOPERATIVE PERIOD; PRIORITY JOURNAL; REOPERATION; RISK FACTOR; SCORING SYSTEM; STROKE;

AGED; ASPIRIN; BLOOD LOSS, SURGICAL; BLOOD TRANSFUSION; CORONARY ARTERY BYPASS; FEMALE; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; MORBIDITY; MYOCARDIAL INFARCTION; POSTOPERATIVE COMPLICATIONS; POSTOPERATIVE HEMORRHAGE; PREOPERATIVE CARE; REOPERATION; RETROSPECTIVE STUDIES; STROKE; TREATMENT OUTCOME; WITHHOLDING TREATMENT;

EID: 79951679615     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.110.957373     Document Type: Article

References (23)

1. Mangano DT; Multicenter Study of Perioperative Ischemia Research Group. Aspirin and mortality from coronary bypass surgery. N Engl J Med. 2002;347:1309-1317. (Pubitemid 35215321)
2. Dacey LJ, Munoz JJ, Johnson ER, Leavitt BJ, Maloney CT, Morton JR, Olmstead EM, Birkmeyer JD, O'Connor GT. Effect of preoperative aspirin use on mortality in coronary artery bypass grafting patients. Ann Thorac Surg. 2000;70:1986-1990. (Pubitemid 32015295)
3. Bybee KA, Powell BD, Valeti U, Rosales AG, Kopecky SL, Mullany C, Wright RS. Preoperative aspirin therapy is associated with improved postoperative outcomes in patients undergoing coronary artery bypass grafting. Circulation. 2005;112(suppl):I-286-I-292.
4. Eagle KA, Guyton RA, Davidoff R, Edwards FH, Ewy GA, Gardner TJ, Hart JC, Herrmann HC, Hillis LD, Hutter AM Jr, Lytle BW, Marlow RA, Nugent WC, Orszulak TA, Antman EM, Smith SC Jr, Alpert JS, Anderson JL, Faxon DP, Fuster V, Gibbons RJ, Gregoratos G, Halperin JL, Hiratzka LF, Hunt SA, Jacobs AK, Ornato JP. ACC/AHA 2004 guideline update for coronary artery bypass graft surgery: summary article: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft Surgery). J Am Coll Cardiol. 2004;44:e213-e310.
5. Ferraris V, Ferraris S, Moliterno D, Camp P, Walenga J, Messmore H, Jeske W, Edwards F, Royston D, Shahian D. The Society of Thoracic Surgeons practice guideline series: aspirin and other antiplatelet agents during operative coronary revascularization (executive summary). Ann Thorac Surg. 2005;79:1454-1461. (Pubitemid 40431898)
6. STS General Thoracic Data Specifications, version 2.081. September 5, 2008. Available at: http://www.sts.org/documents/pdf/ndb/ GeneralThoracicDataSpecsV2081.pdf. Accessed February 24, 2010.
7. Blackstone EH. Comparing apples and oranges. J Thorac Cardiovasc Surg. 2002;123:8-15.
8. Breiman L. Bagging predictors. Mach Learn. 1996;24:123-140. (Pubitemid 126724382)
9. Austin PC, Mamdani MM. A comparison of propensity score methods: a case-study estimating the effectiveness of post-AMI statin use. Stat Med. 2006;25:2084-2106. (Pubitemid 43950281)
10. Bergstralh EJ, Konsanke JL. Technical Report Series No. 56, Computerized Matching of Cases to Controls. Rochester, MN: Department of Health Science Research, Mayo Clinic; 1995.
11. Kallis P, Tooze J, Talbot S, Cowans D, Bevan D, Treasure T. Pre-operative aspirin decreases platelet aggregation and increases postoperative blood loss: a prospective, randomised, placebo controlled, double-blind clinical trial in 100 patients with chronic stable angina. Eur J Cardiothorac Surg. 1994;8:404-409.
12. Ferraris SP, Lough FC, Berry WR, Ferris VA. Preoperative aspirin ingestion increases operative blood loss after coronary artery bypass grafting. Ann Thorac Surg. 1988;45:71-74. (Pubitemid 18034673)
13. Goldman S, Copeland J, Mortiz T, Henderson W, Zadina K, Ovitt T, Doherty J, Read R, Chesler E, Sako Y. Improvement in early saphenous vein graft patency after coronary artery bypass surgery with antiplatelet therapy: results of a Veterans Administration Cooperative Study. Circulation. 1988;77: 1324-1332.
14. Sethi GK, Copeland JG, Goldman S, Mortiz T, Zadina K, Henderson WG. Implications of preoperative administration of aspirin in patients undergoing coronary artery bypass grafting: Department of Veterans Affairs Cooperative Study on Antiplatelet Therapy. J Am Coll Cardiol. 1990;15:15-20. (Pubitemid 20034244)
15. McMillan R. Hemorrhagic disorders: abnormalities of platelet and vascular function. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, PA: Saunders Elsevier; 2007.
16. Banbury MK, Brizzio ME, Rajeswaran J, Lytle BW, Blackstone EH. Transfusion increases the risk of postoperative infection after cardiovascular surgery. J Am Coll Surg. 2006;202:131-138. (Pubitemid 41831483)
17. Gardner TJ. To transfuse or not to transfuse. Circulation. 2007;116: 458-460. (Pubitemid 47450253)
18. Koch C, Li L, Duncan A, Mihaljevic T, Loop F, Starr N, Blackstone E. Transfusion in coronary artery bypass grafting is associated with reduced long-term survival. Ann Thorac Surg. 2006;81:1650-1657. (Pubitemid 350030027)
19. Burger W, Chemnitius JM, Kneissl GD, Rucker G. Low-dose aspirin for secondary cardiovascular prevention: cardiovascular risks after its peri-operative withdrawal versus bleeding risks with its continuation: review and meta-analysis. J Intern Med. 2005;257:399-414. (Pubitemid 40604544)
20. Biondi-Zoccai GG, Lotrionte M, Agostoni P, Abbate A, Fusaro M, Burzotta F, Testa L, Sheiban I, Sangiorgi G. A systematic review and meta-analysis on the hazards of discontinuing or not adhering to aspirin among 50,279 patients at risk for coronary artery disease. Eur Heart J. 2006;27:2667-2674. (Pubitemid 44729867)
21. Eisenberg MJ, Richard PR, Libersan D, Filion KB. Safety of short-term discontinuation of antiplatelet therapy in patients with drug-eluting stents. Circulation. 2009;119:1634-1642.
22. Myles PS, Smith J, Knight J, Cooper DJ, Silbert B, McNeil J, Esmore DS, Buxton B, Krum H, Forbes A, Tonkin A. Aspirin and Tranexamic Acid for Coronary Artery Surgery (ATACAS) Trial: rationale and design. Am Heart J. 2008;155:224-230.
23. ATACAS: Aspirin and Tranexamic Acid for Coronary Artery Surgery: a randomised controlled trial. Available at: http://www.atacas.org.au/centres. Accessed June 26, 2010.