Long-term cultures of stem/progenitor cells from lobular and ductal breast carcinomas under non-adherent conditions

Cytotechnology

Volumn 63, Issue 1, 2011, Pages 67-80

  Nardone, Agostina ^a   Corvigno, Sara ^a   Brescia, Annalisa ^a   D'Andrea, Daniel ^a   Limite, Gennaro ^a   Veneziani, Bianca Maria ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

Author keywords

Breast cancer therapy; Epithelial stromal cells

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; CD24 ANTIGEN; CYCLIN D1; CYTOKERATIN 5; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; HERMES ANTIGEN; VIMENTIN;

ARTICLE; BASAL CELL; BREAST CARCINOMA; CANCER CELL; CANCER CELL CULTURE; CELL ADHESION; CELL FUNCTION; CELL ISOLATION; CELL POPULATION; CELL PROLIFERATION; CELL SELECTION; HUMAN; HUMAN CELL; LUNG CARCINOMA; MYOEPITHELIUM CELL; PRIMARY TUMOR; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; STEM CELL; STEM CELL EXPANSION;

EID: 79951672570     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-010-9328-3     Document Type: Article

References (54)

1. M Al-Hajj MS Wicha A Benito-Hernandez SJ Morrison MF Clarke 2003 Prospective identification of tumorigenic breast cancer cells Proc Natl Acad Sci USA 100 3983 3988 1:CAS:528:DC%2BD3sXivFSqtbs%3D 10.1073/pnas.0530291100 (Pubitemid 36418143)
2. Allred DC (2008) The utility of conventional and molecular pathology in managing breast cancer. Breast Cancer Res 10 (suppl 4):S4
3. R Anbazhagan PP Osin J Bartkova B Nathan EB Lane BA Gusterson 1998 The development of epithelial phenotypes in the human fetal and infant breast J Pathol 184 197 206 1:STN:280:DyaK1c3msFChsA%3D%3D 10.1002/(SICI)1096- 9896(199802)184:2<197::AID-PATH992>3.0.CO;2-J (Pubitemid 28088429)
4. ML Asselin-Labat F Vaillant M Shackleton T Bouras GJ Lindeman JE Visvader 2008 Delineating the epithelial hierarchy in the mouse mammary gland Cold Spring Harb Symp Quant Biol 73 469 478 1:CAS:528:DC%2BD1MXos1erurk%3D 10.1101/sqb.2008.73.020
5. J Bartek J Taylor-Papadimitriou N Miller R Millis 1985 Patterns of expression of keratin 19 as detected with monoclonal antibodies in human breast tissues and tumours Int J Cancer 36 299 306 1:CAS:528:DyaL2MXlvFCiu7g%3D (Pubitemid 16250991)
6. Booth BW, Smith GH (2006) Estrogen receptor-alpha and progesterone receptor are expressed in label-retaining mammary epithelial cells that divide asymmetrically and retain their template DNA strands. Breast Cancer Res 8:R49
7. C Brisken S Duss 2007 Stem cells and the stem cell niche in the breast: an integrated hormonal and developmental perspective Stem Cell Rev 3 147 156 1:CAS:528:DC%2BD2sXhtFantLfP 10.1007/s12015-007-0019-1 (Pubitemid 350129717)
8. LL Campbell K Polyak 2007 Breast tumor heterogeneity: cancer stem cells or clonal evolution? Cell Cycle 37 2332 2338 10.4161/cc.6.19.4914 (Pubitemid 350058682)
9. C Cavaliere S Corvigno M Galgani G Limite A Nardone BM Veneziani 2010 Combined inhibitory effect of formestane and herceptin on a subpopulation of CD44+/CD24low breast cancer cells Cancer Sci 107 1661 1669 10.1111/j.1349-7006. 2010.01593.x
10. ST Chen J Dou R Temple R Agarwal KM Wu S Walker 2008 New therapies from old medicines Nat Biotechnol 26 1077 1083 1:CAS:528:DC%2BD1cXht1aisrrP 10.1038/nbt1008-1077
11. RB Clarke K Spence E Anderson A Howell H Okano CS Potten 2005 A putative human breast stem cell population is enriched for steroid receptor-positive cells Dev Biol 277 443 456 1:CAS:528:DC%2BD2cXhtFGhsr3I 10.1016/j.ydbio.2004.07. 044 (Pubitemid 40022963)
12. MF Clarke JE Dick PB Dirks CJ Eaves CHM Jamieson DL Jones J Visvader IL Weissman GM Wahl 2006 Cancer stem cells-perspectives on current status and future directions: AACR workshop on cancer stem cells Cancer Res 66 9339 9344 1:CAS:528:DC%2BD28XhtVamsr3I 10.1158/0008-5472.CAN-06-3126 (Pubitemid 44623625)
13. AT Collins PA Berry C Hyde MJ Stower NJ Maitland 2005 Prospective identification of tumorigenic prostate cancer stem cells Cancer Res 65 10946 10951 1:CAS:528:DC%2BD2MXht1KjsrzP 10.1158/0008-5472.CAN-05-2018 (Pubitemid 41713363)
14. G Dontu WM Abdallah JM Foley KW Jackson MF Clarke MJ Kawamura MS Wicha 2003 In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells Genes Dev 17 1253 1270 1:CAS:528:DC%2BD3sXktVGmt7s%3D 10.1101/gad.1061803 (Pubitemid 36583168)
15. M Dowsett J Houghton C Iden J Salter J Farndon R A'Hern R Sainsbury M Baum 2006 Benefit from adjuvant tamoxifen therapy in primary breast cancer patients according oestrogen receptor, progesterone receptor, EGF receptor and HER2 status Ann Oncol 17 818 826 1:STN:280:DC%2BD283jtVKltg%3D%3D 10.1093/annonc/mdl016
16. T Frogne AV Laenkholm MB Lyng KL Henriksen AE Lykkesfeldt 2009 Determination of HER2 phosphorylation at tyrosine 1221/1222 improves prediction of poor survival for breast cancer patients with hormone receptor-positive tumors Breast Cancer Res 11 R11 10.1186/bcr2230
17. JC Garbe S Bhattacharya B Merchant E Bassett K Swisshelm HS Feiler AJ Wyrobek MR Stampfer 2009 Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells Cancer Res 69 7557 7568 1:CAS:528:DC%2BD1MXht1Skt7rE 10.1158/0008-5472.CAN-09-0270
18. C Ginestier MH Hur E Charafe-Jauffret F Monville J Dutcher M Brown J Jacquemier P Viens CG Kleer S Liu A Schott D Hayes D Birnbaum MS Wicha G Dontu 2007 ALDH1 is a marker of normal and malignant human mammary stem cells and a predictor of poor clinical outcome Cell Stem Cell 1 555 567 1:CAS:528: DC%2BD2sXhsVahtrvF 10.1016/j.stem.2007.08.014 (Pubitemid 350056407)
19. BA Gusterson MJ Warburton D Mitchell M Ellison AM Neville PS Rudland 1982 Distribution of myoepithelial cells and basement membrane proteins in the normal breast and in benign and malignant breast disease Cancer Res 42 4763 4770 1:STN:280:DyaL3s%2FisVOrtg%3D%3D (Pubitemid 13205987)
20. BA Gusterson DT Ross VJ Heath T Stein 2005 Basal cytokeratins and their relationship to the cellular origin and functional classification of breast cancer Breast Cancer Res 7 143 148 1:CAS:528:DC%2BD2MXls1GjtL4%3D 10.1186/bcr1041 (Pubitemid 40872776)
21. Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, Fitzgibbons PL, Francis G, Goldstein NS, Hayes M, Hicks DG, Lester S, Love R, Mangu PB, McShane L, Miller K, Osborne CK, Paik S, Perlmutter J, Rhodes A, Sasano H, Schwartz JN, Sweep FC, Taube S, Torlakovic EE, Valenstein P, Viale G, Visscher D, Wheeler T, Williams RB, Wittliff JL, Wolff AC (2010) American society of clinical oncology/College of American pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. Arch Pathol Lab Med 134:907-922
22. G Honeth PO Bendahl M Ringnér LH Saal SK Gruvberger-Saal K Lövgren D Grabau M Fernö A Borg C Hegardt 2008 The CD44+/CD24- phenotype is enriched in basal-like breast tumors Breast Cancer Res 10 R53 10.1186/bcr2108
23. S Johnston J Pippen Jr X Pivot M Lichinitser S Sadeghi V Dieras HL Gomez G Romieu A Manikhas MJ Kennedy MF Press J Maltzman A Florance L O'Rourke C Oliva S Stein M Pegram 2009 Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer J Clin Oncol 27 5538 5546 1:CAS:528: DC%2BC3cXhtVWit7w%3D 10.1200/JCO.2009.23.3734
24. B Kaufman JR Mackey MR Clemens PP Bapsy A Vaid A Wardley S Tjulandin M Jahn M Lehle A Feyereislova C Révil A Jones 2009 Trastuzumab plus anastrozole versus anastrozole alone for the treatment of postmenopausal women with human epidermal growth factor receptor 2-positive, hormone receptor-positive metastatic breast cancer: results from the randomized phase III TAnDEM study J Clin Oncol 27 5529 5537 1:CAS:528:DC%2BC3cXhtVWit78%3D 10.1200/JCO.2008.20.6847
25. JM Knowlden IR Hutcheson HE Jones T Madden JM Gee ME Harper D Barrow AE Wakeling RI Nicholson 2003 Elevated levels of epidermal growth factor receptor/c-erbB2 heterodimers mediate an autocrine growth regulatory pathway in tamoxifen-resistant MCF-7 cells Endocrinology 144 1032 1044 1:CAS:528: DC%2BD3sXhslCqtro%3D 10.1210/en.2002-220620 (Pubitemid 36262870)
26. H Korkaya A Paulson F Iovino MS Wicha 2008 HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion Oncogene 27 6120 6130 1:CAS:528:DC%2BD1cXht1Cms7rJ 10.1038/onc.2008.207
27. E Lim F Vaillant D Wu NC Forrest B Pal AH Hart ML Asselin-Labat DE Gyorki T Ward A Partanen F Feleppa LI Huschtscha HJ Thorne FoxSB ConFab M Yan JD French MA Brown GK Smyth JE Visvader GJ Lindeman 2009 Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers Nat Med 15 907 913 1:CAS:528:DC%2BD1MXpt1Onsro%3D 10.1038/nm.2000
28. S Massarweh CK Osborne CJ Creighton L Qin A Tsimelzon S Huang H Weiss M Rimawi R Schiff 2008 Tamoxifen resistance in breast tumors is driven by growth factor receptor signaling with repression of classic estrogen receptor genomic function Cancer Res 68 826 833 1:CAS:528:DC%2BD1cXhtlygtrY%3D 10.1158/0008-5472.CAN-07-2707 (Pubitemid 351206760)
29. R Moll WW Franke DL Schiller 1982 The catalog of human cytokeratins: patterns of expression in normal epithelia, tumors and cultured cells Cell 31 11 24 1:CAS:528:DyaL3sXhtlSjsw%3D%3D 10.1016/0092-8674(82)90400-7 (Pubitemid 13215192)
30. RB Nagle W Bocker JR Davis HW Heid M Kaufmann DO Lucas ED Jarasch 1986 Characterization of breast carcinomas by two monoclonal antibodies distinguishing myoepithelial from luminal epithelial cells J Histochem Cytochem 34 869 881 1:CAS:528:DyaL28XksVSksb8%3D (Pubitemid 16067456)
31. A Nardone C Cavaliere S Corvigno G Limite S De Placido BM Veneziani 2009 A banking strategy toward customized therapy in breast cancer Cell Tissue Bank 10 301 308 10.1007/s10561-009-9124-5
32. LR Oliveira SS Jeffrey A Ribeiro-Silva 2010 Stem cells in human breast cancer Histol Histopathol 25 371 385 1:CAS:528:DC%2BC3cXislamtLw%3D
33. CK Osborne J Shou S Massarweh R Schiff 2005 Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer Clin Cancer Res 11 865s 870s 1:CAS:528: DC%2BD2MXislWgu7k%3D (Pubitemid 40111098)
34. S Paik C Kim N Wolmark 2008 HER2 status and benefit from adjuvant trastuzumab in breast cancer N Engl J Med 358 1409 1411 1:CAS:528: DC%2BD1cXjvFCrsLw%3D 10.1056/NEJMc0801440 (Pubitemid 351468442)
35. SY Park M Gönen HJ Kim F Michor K Polyak 2010 Cellular genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype J Clin Invest 120 636 644 1:CAS:528:DC%2BC3cXhsVOktbs%3D 10.1172/JCI40724
36. S Pece D Tosoni S Confalonieri G Mazzarol M Vecchi S Ronzoni L Bernard G Viale PG Pelicci PP Di Fiore 2010 Biological and molecular heterogeneity of breast cancers correlates with their cancer stem cell content Cell 140 62 73 1:CAS:528:DC%2BC3cXkvVWiur0%3D 10.1016/j.cell.2009.12.007
37. CM Perou T Sorlie MB Eisen M van de Rijn SS Jeffrey CA Rees JR Pollack DT Ross H Johnsen LA Akslen O Fluge A Pergamenschikov C Williams SX Zhu PE Lonning AL Borresen-Dale PO Brown D Botstein 2000 Molecular portraits of human breast tumours Nature 406 747 752 1:CAS:528:DC%2BD3cXmt1CnsLw%3D 10.1038/35021093
38. Petersen OW, Polyak K (2010) Stem cells in the human breast. Cold Spring Harb Perspect Biol 2. doi: 10.1101/cshperspect.a003160
39. D Ponti A Costa N Zaffaroni G Pratesi G Petrangolini D Coradini S Pilotti MA Pierotti MG Daidone 2005 Isolation and in vitro propagation of tumorigenic breast cancer cells with stem/progenitor cell properties Cancer Res 65 5506 5511 1:CAS:528:DC%2BD2MXlslOqsrw%3D 10.1158/0008-5472.CAN-05-0626 (Pubitemid 40911148)
40. L Ronnov-Jessen OW Petersen VE Koteliansky MJ Bissell 1995 The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cells J Clin Invest 95 859 873 1:STN:280:DyaK2M7msVOhsA%3D%3D 10.1172/JCI117736
41. R Schiff CK Osborne 2005 Endocrinology and hormone therapy in breast cancer: new insight into estrogen receptor-alpha function and its implication for endocrine therapy resistance in breast cancer Breast Cancer Res 7 205 211 1:CAS:528:DC%2BD2MXpvFOgt7c%3D 10.1186/bcr1287 (Pubitemid 41387432)
42. M Shackleton F Vaillant KJ Simpson J Stingl GK Smyth ML Asselin-Labat L Wu GJ Lindeman JE Visvader 2006 Generation of a functional mammary gland from a single stem cell Nature 439 84 88 1:CAS:528:DC%2BD28Xht1aqsw%3D%3D 10.1038/nature04372 (Pubitemid 43053633)
43. M Shipitsin LL Campbell P Argani S Weremowicz N Bloushtain-Qimron J Yao T Nikolskaya T Serebryiskaya R Beroukhim M Hu MK Halushka S Sukumar LM Parker KS Anderson LN Harris JE Garber AL Richardson SJ Schnitt Y Nikolsky RS Gelman K Polyak 2007 Molecular definition of breast tumor heterogeneity Cancer Cell 11 259 273 1:CAS:528:DC%2BD2sXjsVymtL0%3D 10.1016/j.ccr.2007.01.013 (Pubitemid 46349843)
44. CF Singer D Gschwantler-Kaulich A Fink-Retter G Pfeiler I Walter G Hudelist S Helmy AC Spiess W Lamm E Kubista 2009 HER2 overexpression and activation, and tamoxifen efficacy in receptor-positive early breast cancer J Cancer Res Clin Oncol 135 807 813 1:CAS:528:DC%2BD1MXlt1Slu74%3D 10.1007/s00432-008-0516-x
45. KE Sleeman H Kendrick A Ashworth CM Isacke MJ Smalley 2006 CD24 staining of mouse mammary gland cells defines luminal epithelial, myoepithelial/basal and non-epithelial cells Breast Cancer Res 8 R7 10.1186/bcr1371 (Pubitemid 44644832)
46. KE Sleeman H Kendrick D Robertson CM Isacke A Ashworth MJ Smalley 2007 Dissociation of estrogen receptor expression and in vivo stem cell activity in the mammary gland J Cell Biol 176 19 26 1:CAS:528:DC%2BD2sXktVOnug%3D%3D 10.1083/jcb.200604065 (Pubitemid 46041676)
47. T Sorlie CM Perou R Tibshirani T Aas S Geisler H Johnsen T Hastie MB Eisen M van de Rijn SS Jeffrey T Thorsen H Quist JC Matese PO Brown D Botstein P Eystein Lonning AL Borresen-Dale 2001 Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications Proc Natl Acad Sci USA 98 10869 10874 1:CAS:528:DC%2BD3MXntVGmsbo%3D 10.1073/pnas. 191367098 (Pubitemid 32878711)
48. Sorlie T, Tibshirani R, Parker J, Hastie T, Marron JS, Nobel A, Deng S, Johnsen H, Pesich R, Geisler S, Demeter J, Perou CM, Lønning PE, Brown PO, Børresen-Dale AL, Botstein D (2003) Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 100:8418-8423
49. Sotiriou C, Neo SY, McShane LM, Korn EL, Long PM, Jazaeri A, Martiat P, Fox SB, Harris AL, Liu ET (2003) Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci USA 100:10393-10398 (Pubitemid 37071889)
50. J Stingl P Eirew I Ricketson M Shackleton F Vaillant D Choi HI Li CJ Eaves 2006 Purification and unique properties of mammary epithelial stem cells Nature 439 993 997 1:CAS:528:DC%2BD28Xhs1KjsbY%3D (Pubitemid 43292419)
51. T Suzuki Y Miki N Ohuchi H Sasano 2008 Intratumoral estrogen production in breast carcinoma: significance of aromatase Breast Cancer 15 270 277 10.1007/s12282-008-0062-z
52. van de Vijver MJ, He YD, van't Veer LJ, Dai H, Hart AA, Voskuil DW, Schreiber GJ, Peterse JL, Roberts C, Marton MJ, Parrish M, Atsma D, Witteveen A, Glas A, Delahaye L, van der Velde T, Bartelink H, Rodenhuis S, Rutgers ET, Friend SH, Bernards R (2002) A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 347:1999-2009 (Pubitemid 35461656)
53. BM Veneziani V Criniti C Cavaliere S Corvigno A Nardone S Picarelli G Tortora F Ciardiello G Limite S De Placido 2007 In vitro expansion of human breast cancer epithelial and mesenchymal stromal cells: optimization of a coculture model for personalized therapy approaches Mol Cancer Ther 6 3091 3100 1:CAS:528:DC%2BD2sXhsVCjsrzP 10.1158/1535-7163.MCT-07-0356
54. R Villadsen AJ Fridriksdottir L Rønnov-Jessen T Gudjonsson F Rank MA Labarge MJ Bissell OW Petersen 2007 Evidence for a stem cell hierachy in the adult human breast J Cell Biol 177 87 101 1:CAS:528:DC%2BD2sXktlKltr0%3D 10.1083/jcb.200611114 (Pubitemid 46588404)