Review of the performance of the 3T3 NRU in vitro phototoxicity assay in the pharmaceutical industry

Experimental and Toxicologic Pathology

Volumn 63, Issue 3, 2011, Pages 209-214

  Lynch, Anthony M ^a   Wilcox, Phillip ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

3T3 NRU; Photogenotoxicity; Photosafety; Phototoxicity; Risk assessment

Indexed keywords

QUINOLINE DERIVED ANTIINFECTIVE AGENT; TOXIC SUBSTANCE;

ARTICLE; ASSAY; DRUG INDUSTRY; DRUG SAFETY; GENOTOXICITY; HEALTH HAZARD; HUMAN; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHOTOTOXICITY; PRACTICE GUIDELINE; RISK ASSESSMENT; ULTRAVIOLET RADIATION;

ANIMALS; BALB 3T3 CELLS; DERMATITIS, PHOTOTOXIC; DRUG EVALUATION, PRECLINICAL; DRUG INDUSTRY; HUMANS; MICE; NEUTRAL RED; PHARMACEUTICAL PREPARATIONS; PHOTOCHEMICAL PROCESSES; PREDICTIVE VALUE OF TESTS; TOXICITY TESTS; ULTRAVIOLET RAYS;

ANIMALIA;

EID: 79951671006     PISSN: 09402993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etp.2009.12.001     Document Type: Article

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