Helix conformation of a small peptide melittin in a methanol-water mixed solvent studied by NMR

Protein and Peptide Letters

Volumn 18, Issue 3, 2011, Pages 318-326

  Miura, Yoshinori ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

helix; Hydrogen bond; Hydrophobic interaction; Melittin; Methanol water mixed solvent; NMR; Phase diagram

Indexed keywords

MELITTIN; METHANOL; SOLVENT; WATER;

ARTICLE; CHEMISTRY; NUCLEAR MAGNETIC RESONANCE; PROTEIN SECONDARY STRUCTURE; TEMPERATURE;

MELITTEN; METHANOL; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, SECONDARY; SOLVENTS; TEMPERATURE; WATER;

APOIDEA;

EID: 79951669244     PISSN: 09298665     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986611794578387     Document Type: Article

References (16)

1. Dempsey, C.E. The action of melittin on membranes. Biochimica et Biophysica Acta, 1990, 1031, 143-230.
2. 1HNMR studies of monomeric melittin in aqueous solution. Biochem. Biophys. Acta, 1980, 622, 219-230.
3. 1HNMR studies of self-aggregation of melittin in aqueous solution. Biochem. Biophys. Acta, 1980, 622, 231-244.
4. Bello, J.; Bello, H.R.; Granados, E. Conformation and aggregation of melittin: dependence on pH and concentration. Biochemistry, 1982, 21, 461-465.
5. Schubert, D.; Pappert, G.; Boss, K. Dose dimeric melittin occur in aqueous solution? Biophys. J., 1985, 48, 327-329.
6. Quay, S.C.; Condie, C.C. Conformational studies of aqueous melittin: thermodynamic parameters of the monomer-tetramer selfassociation reaction. Biochemistry, 1983, 22, 695-700.
7. Goto, Y.; Hagihara, Y. Mechanism of the conformational transition of melittin. Biochemistry, 1992, 31, 732-738.
8. Bazzo, R.; Tappin, M.J.; Pastore, A.; Harvey, T.S.; Carver, J.A.; Campbell, I.D. The structure of melittin: A 1H-NMR study in methanol. Eur. J. Biochem., 1988, 173, 139-146.
9. Dempsey, C.E. pH dependence of hydrogen exchange from backbone peptide amides of melittin in methanol. Biochemistry, 1988, 27, 6893-6901.
10. Hirota, N.; Mizuno, K.; Goto, Y. Group additive contributions to the alcohol-induced α-helix formation of melittin: implication for the mechanism of the alcohol effects on proteins. J. Mol. Biol., 1998, 275, 365-378. (Pubitemid 28030010)
11. α-NMR assignments of melittin in methanol and chemical shift correlations with secondary structure. J. Biomol. NMR, 1993, 3, 639-652.
12. Hagihara, Y.; Kataoka, M.; Aimoto, S.; Goto, Y. Charge repulsion in the conformational stability of melittin. Biochemistry, 1992, 31, 11908-11914.
13. Hagihara, Y.; Oobatake, M.; Goto, Y. Thermal unfolding of tetrameric melittin: comparison with the molten globule state of cytochrome c. Protein Sci., 1994, 3, 1418-1429. (Pubitemid 24314461)
14. Wilcox, W.; Eisenberg, D. Thermodynamics of melittin tetramerization determined by circular dichroism and implications for protein folding. Protein Sci., 1992, 1, 641-653. (Pubitemid 23009199)
15. Van de Ven, Frank J. M. Multidimensional NMR in Liquids.; Wiley-VCH: New York, 1995.
16. Wüthrich, K. NMR of Proteins and Nucleic Acids.; John Wiley & Sons: New York, 1986.