False elevation of carboxyhemoglobin: Case report

Pediatric Emergency Care

Volumn 27, Issue 2, 2011, Pages 138-140

  Mehrotra, Shruti ^a,b   Edmonds, Marcia ^a,b   Lim, Rodrick K ^a,b  

^a LONDON HEALTH SCIENCES CENTRE   (Canada)

^b WESTERN UNIVERSITY   (Canada)

Author keywords

carbon monoxide; Carboxyhemoglobin; fetal hemoglobin; gas chromatography; spectrophotometry

Indexed keywords

CARBOXYHEMOGLOBIN; OXYGEN;

ARTICLE; CARBON MONOXIDE INTOXICATION; CASE REPORT; FEMALE; HEMOGLOBIN BLOOD LEVEL; HUMAN; INFANT; LUNG BURN; OXYGEN THERAPY; SPECTROPHOTOMETRY;

CARBON MONOXIDE POISONING; CARBOXYHEMOGLOBIN; DIAGNOSIS, DIFFERENTIAL; EMERGENCY SERVICE, HOSPITAL; FALSE POSITIVE REACTIONS; FEMALE; FETAL HEMOGLOBIN; HUMANS; INFANT; OXYGEN INHALATION THERAPY; RISK ASSESSMENT; SMOKE INHALATION INJURY; SPECTROPHOTOMETRY;

EID: 79951662429     PISSN: 07495161     EISSN: None     Source Type: Journal    
DOI: 10.1097/PEC.0b013e318209f076     Document Type: Article

References (16)

1. Centers for Disease Control and Prevention. Carbon monoxide related deaths, United States, 1999-2004. MMWR. 2007;56:1309-1312.
2. Centers for Disease Control and Prevention. Nonfatal, unintentional, non-fire-related carbon monoxide exposures, United States, 2004-2006. MMWR. 2008;57:896-899.
3. Baum CR. What's new in pediatric carbon monoxide poisoning? Clin Pediatr Emerg Med. 2008;9(1):43-46. (Pubitemid 351331134)
4. Bozeman WP, Myers RAM, Barish RA. Confirmation of the pulse oximetry gap in carbon monoxide poisoning. Ann Emerg Med. 1997;30:608-611. (Pubitemid 27469165)
5. James R. The ins and outs of laboratory testing. EMN. 2001;23(12):11-12.
6. Russel MAH. Blood carboxyhemoglobin changes during tobacco smoking. Postgrad Med J. 1973;49(576):684-687.
7. Coburn RF. Endogenous carbon monoxide production. N Engl J Med. 1970;282:207-209.
8. Sjostrand T. The formation of carbon monoxide by the decomposition of haemoglobin in vivo. Acta Physiol Scand. 1952;26:338-344.
9. Malefant AL, Gambino SR, Waraska AJ, et al. Spectrophotometric determination of hemoglobin concentration and percent oxyhemoglobin and carboxyhemoglobin saturation. Clin Chem. 1968;14:789.
10. Vreman HJ, Ronquillo RB, Ariagno RL, et al. Interference of fetal hemoglobin with the spectrophotometric measurement of carboxyhemoglobin. Clin Chem. 1988;34(5):975-977.
11. Wimberley PD, Siggaard-Andersen O, Fogh-Anderson N. Accurate measurements of hemoglobin oxygen saturation, and fractions of carboxyhemoglobin and methemoglobin in fetal blood using radiometer OSM3: corrections for fetal hemoglobin fraction and pH. Scand J Clin Lab Invest. 1990;50(suppl 203): 235):235-239.
12. Perrone J, Hoffman RS. Falsely elevated carboxyhemoglobin levels secondary to fetal hemoglobin. Acad Emerg Med. 1996;3(3):287-289. (Pubitemid 26153141)
13. Ohls RK, Christensen RD. Development of the hematopoeitic system. In: Kliegman RM, Behrman RE, Jenson HB, et al, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, PA: WB Saunders; 2007.
14. Chernoff AI. The human hemoglobins in health and disease. N Engl J Med. 1955;253:322.
15. MHRA Blood Gas Analyzer Survey Manual. BrLnshLj, Denmark: Radiometer Medical ApS; 2004. Available at: www.radiometer.com. Accessed December 3, 2008.
16. Beneteau-Burnat B, Pernet P, Pilon A, et al. Evaluation of the GEM Premier 4000: a compact blood gas CO-oximeter and electrolyte analyzer for point-of-care and laboratory testing. Clin Chem Lab Med. 2008;46(2):271-279.