Regulation of immunoglobulin synthesis, modification, and trafficking by the unfolded protein response: A quantitative approach

Methods in Enzymology

Volumn 491, Issue , 2011, Pages 309-325

  Drori, Adi ^a   Tirosh, Boaz ^a  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOPLASM PROTEIN; DIGITONIN; IMMUNOGLOBULIN; TRYPSIN; X BOX BINDING PROTEIN 1;

ARTICLE; CELL DIFFERENTIATION; CELL ISOLATION; CELL LABELING; CELL PERMEABILIZATION; CELL SURVIVAL; CYTOLYSIS; ENDOPLASMIC RETICULUM; GLYCOPROTEIN SYNTHESIS; IMMUNE DEFICIENCY; IMMUNOGLOBULIN PRODUCTION; IMMUNOPRECIPITATION; KIDNEY FAILURE; LIPOGENESIS; LUNG INSUFFICIENCY; MEASUREMENT; MULTIPLE MYELOMA; NONHUMAN; PHYSIOLOGY; PLASMA CELL; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; PROTEIN TARGETING; PROTEIN TRANSPORT; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; RETROVIRUS; RETROVIRUS INFECTION; RNA SPLICING; SPLEEN; SPLEEN CELL; UNFOLDED PROTEIN RESPONSE; VIRAL GENE DELIVERY SYSTEM;

EID: 79951622096     PISSN: 00766879     EISSN: None     Source Type: Book Series    
DOI: 10.1016/B978-0-12-385928-0.00017-1     Document Type: Chapter

References (16)

1. R. Amitay, S. Bar-Nun, J. Haimovich, E. Rabinovich, and I. Shachar Post-translational regulation of IgM expression in B lymphocytes. Selective nonlysosomal degradation of assembled secretory IgM is temperature-dependent and occurs prior to the trans-Golgi J. Biol. Chem. 266 1991 12568 12573 (Pubitemid 21907132)
2. G. Blobel, and B. Dobberstein Transfer of proteins across membranes. I. Presence of proteolytically processed and unprocessed nascent immunoglobulin light chains on membrane-bound ribosomes of murine myeloma J. Cell. Biol. 67 1975 835 851
3. J.S. Cox, C.E. Shamu, and P. Walter Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase Cell 73 1993 1197 1206 (Pubitemid 23180493)
4. A. Drori, S. Misaghi, J. Haimovich, M. Messerle, and B. Tirosh Prolonged endoplasmic reticulum stress promotes mislocalization of immunoglobulins to the cytoplasm Mol. Immunol. 47 2010 1719 1727
5. A.M. Fra, C. Fagioli, D. Finazzi, R. Sitia, and C.M. Alberini Quality control of ER synthesized proteins: An exposed thiol group as a three-way switch mediating assembly, retention and degradation EMBO J. 12 1993 4755 4761 (Pubitemid 23330281)
6. N.N. Iwakoshi, A.H. Lee, P. Vallabhajosyula, K.L. Otipoby, K. Rajewsky, and L.H. Glimcher Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1 Nat. Immunol. 4 2003 321 329 (Pubitemid 36432313)
7. S.W. Kang, N.S. Rane, S.J. Kim, J.L. Garrison, J. Taunton, and R.S. Hegde Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway Cell 127 2006 999 1013 (Pubitemid 44803063)
8. A.H. Lee, N.N. Iwakoshi, K.C. Anderson, and L.H. Glimcher Proteasome inhibitors disrupt the unfolded protein response in myeloma cells Proc. Natl. Acad. Sci. USA 100 2003 9946 9951 (Pubitemid 37087048)
9. C.G. Levine, D. Mitra, A. Sharma, C.L. Smith, and R.S. Hegde The efficiency of protein compartmentalization into the secretory pathway Mol. Biol. Cell 16 2005 279 291 (Pubitemid 40024310)
10. A.M. McGehee, S.K. Dougan, E.J. Klemm, G. Shui, B. Park, Y.M. Kim, N. Watson, M.R. Wenk, H.L. Ploegh, and C.C. Hu XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis J. Immunol. 183 2009 3690 3699
11. S.A. Oracki, J.A. Walker, M.L. Hibbs, L.M. Corcoran, and D.M. Tarlinton Plasma cell development and survival Immunol. Rev. 237 2010 140 159
12. A.M. Reimold, N.N. Iwakoshi, J. Manis, P. Vallabhajosyula, E. Szomolanyi-Tsuda, E.M. Gravallese, D. Friend, M.J. Grusby, F. Alt, and L.H. Glimcher Plasma cell differentiation requires the transcription factor XBP-1 Nature 412 2001 300 307 (Pubitemid 32691837)
13. D.T. Rutkowski, and R.S. Hegde Regulation of basal cellular physiology by the homeostatic unfolded protein response J. Cell. Biol. 189 2010 783 794
14. A.L. Shaffer, M. Shapiro-Shelef, N.N. Iwakoshi, A.H. Lee, S.B. Qian, H. Zhao, X. Yu, L. Yang, B.K. Tan, A. Rosenwald, E.M. Hurt, and E. Petroulakis XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation Immunity 21 2004 81 93 (Pubitemid 38925269)
15. R. Sriburi, S. Jackowski, K. Mori, and J.W. Brewer XBP1: A link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum J. Cell Biol. 167 2004 35 41 (Pubitemid 39363412)
16. B. Tirosh, N.N. Iwakoshi, L.H. Glimcher, and H.L. Ploegh XBP-1 specifically promotes IgM synthesis and secretion, but is dispensable for degradation of glycoproteins in primary B cells J. Exp. Med. 202 2005 505 516 (Pubitemid 41186949)