Intracerebroventricular administration of an endothelin ET B-receptor agonist increases expression of matrix metalloproteinase-2 and -9 in rat brain

Journal of Pharmacological Sciences

Volumn 114, Issue 4, 2010, Pages 433-443

  Koyama, Yutaka ^a   Tanaka, Kazuhiro ^a  

^a OSAKA OHTANI UNIVERSITY   (Japan)

Author keywords

Astrocyte; Brain injury; Endothelin 1; Gene expression; Matrix metalloproteinase (MMP)

Indexed keywords

ENDOTHELIN 1 [1,3,11,15 ALANINE]; GELATINASE A; GELATINASE B; INTERSTITIAL COLLAGENASE; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE 14; MESSENGER RNA; PYRROLIDINE DITHIOCARBAMATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN INJURY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SYNTHESIS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; MALE; NERVE CELL CULTURE; NERVE CELL STIMULATION; NONHUMAN; PROTEIN CONTENT; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; RAT; SIGNAL TRANSDUCTION;

EID: 79951619846     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1254/jphs.10195FP     Document Type: Article

References (42)

1. Mott JD, Werb Z. Regulation of matrix biology by matrix metalloproteinases. Curr Opin Cell Biol. 2004;16:558-564. (Pubitemid 39201241)
2. Dzwonek J, Rylski M, Kaczmarek L. Matrix metalloproteinases and their endogenous inhibitors in neuronal physiology of the adult brain. FEBS Lett. 2004;567:129-135. (Pubitemid 38686435)
3. Rosell A, Lo EH. Multiphasic roles for matrix metalloproteinases after stroke. Curr Opin Pharmacol. 2008;8:82-89.
4. Ethell IM, Ethell DW. Matrix metalloproteinases in brain development and remodeling: synaptic functions and targets. J Neurosci Res. 2007;85:2813-2823. (Pubitemid 47523564)
5. Vecil GG, Larsen PH, Corley SM, Herx LM, Besson A, Goodyer CG, et al. Interleukin-1 is a key regulator of matrix metalloproteinase-9 expression in human neurons in culture and following mouse brain trauma in vivo. J Neurosci Res. 2000;61:212-224. (Pubitemid 30451809)
6. Clements JM, Cossins JA, Wells GM, Corkill DJ, Helfrich K, Wood LM, et al. Matrix metalloproteinase expression during experimental autoimmune encephalomyelitis and effects of a combined matrix metalloproteinase and tumour necrosis factor-alpha inhibitor. J Neuroimmunol. 1997;74:85-94. (Pubitemid 27128981)
7. Planas AM, Solé S, Justicia C. Expression and activation of matrix metalloproteinase-2 and -9 in rat brain after transient focal cerebral ischemia. Neurobiol Dis. 2001;8:834-846. (Pubitemid 33055599)
8. Rosenberg GA, Cunningham LA, Wallace J, Alexander S, Estrada EY, Grossetete M, et al. Immunohistochemistry of matrix metalloproteinases in reperfusion injury to rat brain: activation of MMP-9 linked to stromelysin-1 and microglia in cell cultures. Brain Res. 2001;893:104-112. (Pubitemid 32171902)
9. Rivera S, Ogier C, Jourquin J, Timsit S, Szklarczyk AW, Miller K, et al. Gelatinase B and TIMP-1 are regulated in a cell- and time-dependent manner in association with neuronal death and glial reactivity after global forebrain ischemia. Eur J Neurosci. 2002;15:19-32. (Pubitemid 35478006)
10. Muir EM, Adcock KH, Morgenstern DA, Clayton R, von Stillfried N, Rhodes K, et al. Matrix metalloproteases and their inhibitors are produced by overlapping populations of activated astrocytes. Brain Res Mol Brain Res. 2002;100:103-117. (Pubitemid 34465583)
11. von Gertten C, Holmin S, Mathiesen T, Nordqvist AC. Increases in matrix metalloproteinase-9 and tissue inhibitor of matrix metalloproteinase-1 mRNA after cerebral contusion and depolarization. J Neurosci Res. 2003;73:803-810. (Pubitemid 37071734)
12. Adair JC, Charlie J, Dencoff JE, Kaye JA, Quinn JF, Camicioli RM, et al. Measurement of gelatinase B (MMP-9) in the cerebrospinal fluid of patients with vascular dementia and Alzheimer disease. Stroke. 2004;35:159-162.
13. Lindberg RL, De Groot CJ, Montagne L, Freitag P, van der Valk P, Kappos L, et al. The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis. Brain. 2001;124:1743-1753. (Pubitemid 32845436)
14. Rosenberg GA, Estrada EY, Dencoff JE. Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain. Stroke. 1998;29:2189-2195. (Pubitemid 28443538)
15. Sood RR, Taheri S, Candelario-Jalil E, Estrada EY, Rosenberg GA. Early beneficial effect of matrix metalloproteinase inhibition on blood-brain barrier permeability as measured by magnetic resonance imaging countered by impaired long-term recovery after stroke in rat brain. J Cereb Blood Flow Metab. 2008;28:431-438. (Pubitemid 351161291)
16. Wang J, Tsirka SE. Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage. Brain. 2005:128:1622-1633. (Pubitemid 41373681)
17. Lee SR, Tsuji K, Lee SR, Lo EH. Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia. J Neurosci. 2004;24:671-678. (Pubitemid 38166493)
18. Asahi M, Wang X, Mori T, Sumii T, Jung JC, Moskowitz MA, et al. Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia. J Neurosci. 2001:21:7724-7732. (Pubitemid 32904971)
19. Wang X, Jung J, Asahi M, Chwang W, Russo L, Moskowitz MA, et al. Effects of matrix metalloproteinase-9 gene knock-out on morphological and motor outcomes after traumatic brain injury. J Neurosci. 2000;20:7037-7042.
20. Wu CY, Hsieh HL, Jou MJ, Yang CM. Involvement of p42/p44 MAPK, p38 MAPK, JNK and nuclear factor-kappa B in interleukin-1β-induced matrix metalloproteinase-9 expression in rat brain astrocytes. J Neurochem. 2004;90:1477-1488.
21. Hsieh HL, Yen MH, Jou MJ, Yang CM. Intracellular signalings underlying bradykinin-induced matrix metalloproteinase-9 expression in rat brain astrocyte-1. Cell Signal. 2004;16:1163-1176.
22. Choi MS, Kim YE, Lee WJ, Choi JW, Park GH, Kim SD, et al. Activation of protease-activated receptor1 mediates induction of matrix metalloproteinase-9 by thrombin in rat primary astrocytes. Brain Res Bull. 2008;76:368-375.
23. Lee SR, Guo SZ, Scannevin RH, Magliaro BC, Rhodes KJ, Wang X, et al. Induction of matrix metalloproteinase, cytokines and chemokines in rat cortical astrocytes exposed to plasminogen activators. Neurosci Lett. 2007:417:1-5. (Pubitemid 46533879)
24. Nie XJ, Olsson Y. Endothelin peptides in brain diseases. Rev Neurosci. 1996;7:177-186. (Pubitemid 26397658)
25. Ostrow LW, Sachs F. Mechanosensation and endothelin in astrocytes - hypothetical roles in CNS pathophysiology. Brain Res Brain Res Rev. 2005;48:488-508. (Pubitemid 40725402)
26. Sharkey J, Ritchie IM, Kelly PA. Perivascular microapplication of endothelin-1: a new model of focal cerebral ischaemia in the rat. J Cereb Blood Flow Metab. 1993;13:865-871. (Pubitemid 23244756)
27. Macrae IM, Robinson MJ, Graham DI, Reid JL, McCulloch J. Endothelin-1-induced reductions in cerebral blood flow: dose dependency, time course, and neuropathological consequences. J Cereb Blood Flow Metab. 1993;13:276-284. (Pubitemid 23067462)
28. Rogers SD, Peters CM, Pomonis JD, Hagiwara H, Ghilardi JR, Mantyh PW. Endothelin B receptors are expressed by astrocytes and regulate astrocyte hypertrophy in the normal and injured CNS. Glia. 2003;41:180-190. (Pubitemid 36262195)
29. Pekny M, Nilsson M. Astrocyte activation and reactive gliosis. Glia. 2005;50:427-434. (Pubitemid 40780846)
30. Sofroniew MV. Reactive astrocytes in neural repair and protection. Neuroscientist. 2005;11:400-407. (Pubitemid 41339226)
31. B receptors. Eur J Neurosci. 1997;9:895-901.
32. B receptor agonist increases expressions of GDNF and BDNF in rat brain. Eur J Neurosci. 2003;18:887-894.
33. B receptor agonist increases expression of tissue inhibitor of matrix metalloproteinase-1 and -3 in rat brain. Neuroscience. 2007;147:620-630.
34. Vaillant C, Didier-Bazès M, Hutter A, Belin MF, Thomasset N. Spatiotemporal expression patterns of metalloproteinases and their inhibitors in the postnatal developing rat cerebellum. J Neurosci. 1999;9:4994-5004. (Pubitemid 29270134)
35. Szklarczyk A, Lapinska J, Rylski M, McKay RD, Kaczmarek L. Matrix metalloproteinase-9 undergoes expression and activation during dendritic remodeling in adult hippocampus. J Neurosci. 2002;22:920-930. (Pubitemid 34141772)
36. Gadea A, Schinelli S, Gallo V. Endothelin-1 regulates astrocyte proliferation and reactive gliosis via a JNK/c-Jun signaling pathway. J Neurosci. 2008;28:2394-2408. (Pubitemid 351348181)
37. Koyama Y, Takemura M, Fujiki K, Ishikawa N, Shigenaga Y, Baba A. BQ788, an endothelin ETB receptor antagonist, attenuates stab wound injury-induced reactive astrocytes in rat brain. Glia. 1999;26:268-271. (Pubitemid 29212044)
38. Roux S, Breu V, Giller T, Neidhart W, Ramuz H, Coassolo P, et al. Ro 61-1790, a new hydrosoluble endothelin antagonist: general pharmacology and effects on experimental cerebral vasospasm. J Pharmacol Exp Ther. 1997;283:1110-1118. (Pubitemid 28016483)
39. A receptors. Brain Res. 1994;658:179-184.
40. Wang HH, Hsieh HL, Wu CY, Yang CM. Endothelin-1 enhances cell migration via matrix metalloproteinase-9 up-regulation in brain astrocytes. J Neurochem. 2010;113:1133-1149.
41. Koyama Y, Yoshioka Y, Shinde M, Matsuda T, Baba A. Focal adhesion kinase mediates endothelin-induced cyclin D3 expression in rat cultured astrocytes. J Neurochem. 2004;90:904-912. (Pubitemid 39099972)
42. Koyama Y, Tanaka K. Endothelins stimulate the production of stromelysin-1 in cultured rat astrocytes. Biochem Biophys Res Commun. 2008;371:659-663.