메뉴 건너뛰기




Volumn 19, Issue 2, 2011, Pages 81-89

Genetic analysis in cardiovascular disease: A clinical perspective

Author keywords

cardiovascular disease; genetic analysis

Indexed keywords

CLOPIDOGREL; UNTRANSLATED RNA; WARFARIN;

EID: 79951606154     PISSN: 10615377     EISSN: None     Source Type: Journal    
DOI: 10.1097/CRD.0b013e318207ffac     Document Type: Review
Times cited : (15)

References (80)
  • 1
    • 0035094764 scopus 로고    scopus 로고
    • Variation is the spice of life
    • DOI 10.1038/85776
    • Kruglyak L, Nickerson DA. Variation is the spice of life. Nat Genet. 2001;27:234-236. (Pubitemid 32201838)
    • (2001) Nature Genetics , vol.27 , Issue.3 , pp. 234-236
    • Kruglyak, L.1    Nickerson, D.A.2
  • 2
    • 40649100317 scopus 로고    scopus 로고
    • Hypertrophic cardiomyopathy: The genetic determinants ofclinical disease expression
    • Keren A, Syrris P, McKenna WJ. Hypertrophic cardiomyopathy: the genetic determinants ofclinical disease expression. Nat Clin Pract Cardiovasc Med. 2008;5:158-168.
    • (2008) Nat Clin Pract Cardiovasc Med. , vol.5 , pp. 158-168
    • Keren, A.1    Syrris, P.2    McKenna, W.J.3
  • 3
    • 77952966596 scopus 로고    scopus 로고
    • Narrative review: Harnessing molecular genetics for the diagnosis and management ofhypertrophic cardiomyopathy
    • Wang L, Seidman JG, Seidman CE. Narrative review: harnessing molecular genetics for the diagnosis and management ofhypertrophic cardiomyopathy. Ann Intern Med. 2010;152:513-520.
    • (2010) Ann Intern Med. , vol.152 , pp. 513-520
    • Wang, L.1    Seidman, J.G.2    Seidman, C.E.3
  • 4
    • 67649854428 scopus 로고    scopus 로고
    • Diagnostic, prognostic, and therapeutic implications ofgenetic testing for hypertrophic cardiomyopathy
    • Bos JM, Towbin JA, Ackerman MJ. Diagnostic, prognostic, and therapeutic implications ofgenetic testing for hypertrophic cardiomyopathy. JAm Coll Cardiol. 2009;54:201-211.
    • (2009) JAm Coll Cardiol. , vol.54 , pp. 201-211
    • Bos, J.M.1    Towbin, J.A.2    Ackerman, M.J.3
  • 5
    • 79951593705 scopus 로고    scopus 로고
    • Gene Dx Inc Gene Dx Inc Available at Accessed March 28, 2010
    • Gene Dx Inc. Cardiology Genetics Testing Services. Gene Dx Inc;2010. Available at: http://www.genedx.com/site/cardiology-genetic-testing-services. Accessed March 28, 2010.
    • (2010) Cardiology Genetics Testing Services.
  • 6
    • 35548997132 scopus 로고    scopus 로고
    • Role of Genetic Analysis in the Management of Patients With Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy
    • DOI 10.1016/j.jacc.2007.08.008, PII S0735109707026496
    • Sen-Chowdhry S, Syrris P, McKenna WJ. Role of genetic analysis in the management of patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy. JAm Coll Cardiol. 2007;50:1813-1821. (Pubitemid 350007965)
    • (2007) Journal of the American College of Cardiology , vol.50 , Issue.19 , pp. 1813-1821
    • Sen-Chowdhry, S.1    Syrris, P.2    McKenna, W.J.3
  • 7
    • 77949878973 scopus 로고    scopus 로고
    • Desmoglein-2 and desmocollin-2 mutations in Dutch arrhythmogenic right ventricular dysplasia/cardiomypathy patients: Results from a multicenter study
    • Bhuiyan ZA, Jongbloed JD, van der Smagt J, et al. Desmoglein-2 and desmocollin-2 mutations in Dutch arrhythmogenic right ventricular dysplasia/cardiomypathy patients: results from a multicenter study. Circ Cardiovasc Genet. 2009;2:418-427.
    • (2009) Circ Cardiovasc Genet. , vol.2 , pp. 418-427
    • Bhuiyan, Z.A.1    Jongbloed, J.D.2    Van Der Smagt, J.3
  • 8
    • 77949908549 scopus 로고    scopus 로고
    • Comprehensive desmosome mutation analysis in north Americans with arrhythmogenic right ventricular dysplasia/cardiomyopathy
    • den Haan AD, Tan BY, Zikusoka MN, et al. Comprehensive desmosome mutation analysis in north Americans with arrhythmogenic right ventricular dysplasia/cardiomyopathy. Circ Cardiovasc Genet. 2009;2:428-435.
    • (2009) Circ Cardiovasc Genet. , vol.2 , pp. 428-435
    • Den Haan, A.D.1    Tan, B.Y.2    Zikusoka, M.N.3
  • 10
    • 41649107651 scopus 로고    scopus 로고
    • Arrhythmogenic right ventricular cardiomyopathy type 5 is a fully penetrant, lethal arrhythmic disorder caused by a missense mutation in the TMEM43 gene
    • Merner ND, Hodgkinson KA, Haywood AF, et al. Arrhythmogenic right ventricular cardiomyopathy type 5 is a fully penetrant, lethal arrhythmic disorder caused by a missense mutation in the TMEM43 gene. Am J Hum Genet. 2008;82:809-821.
    • (2008) Am J Hum Genet. , vol.82 , pp. 809-821
    • Merner, N.D.1    Hodgkinson, K.A.2    Haywood, A.F.3
  • 11
    • 77249109399 scopus 로고    scopus 로고
    • Dilated cardiomyopathy
    • Jefferies JL, Towbin JA. Dilated cardiomyopathy. Lancet. 2010;375:752-762.
    • (2010) Lancet. , vol.375 , pp. 752-762
    • Jefferies, J.L.1    Towbin, J.A.2
  • 12
    • 0037050022 scopus 로고    scopus 로고
    • The failing heart
    • DOI 10.1038/415227a
    • Towbin JA, Bowles NE. The failing heart. Nature. 2002;415:227-233. (Pubitemid 34059529)
    • (2002) Nature , vol.415 , Issue.6868 , pp. 227-233
    • Towbin, J.A.1    Bowles, N.E.2
  • 13
    • 77953023261 scopus 로고    scopus 로고
    • Coding sequence rare variants identified in MYBPC3, MYH6, TPM1, TNNC1, and TNNI3 from 312 patients with familial or idiopathic dilated cardiomyopathy
    • Hershberger RE, Norton N, Morales A, et al. Coding sequence rare variants identified in MYBPC3, MYH6, TPM1, TNNC1, and TNNI3 from 312 patients with familial or idiopathic dilated cardiomyopathy. Circ Cardiovasc Genet. 2010;3:155-161.
    • (2010) Circ Cardiovasc Genet. , vol.3 , pp. 155-161
    • Hershberger, R.E.1    Norton, N.2    Morales, A.3
  • 14
    • 1042268063 scopus 로고    scopus 로고
    • Inherited Arrhythmogenic Diseases: The Complexity Beyond Monogenic Disorders
    • DOI 10.1161/01.RES.0000115750.12807.7E
    • Priori SG. Inherited arrhythmogenic diseases: the complexity beyond mono-genic disorders. Circ Res. 2004;94:140-145. (Pubitemid 38197445)
    • (2004) Circulation Research , vol.94 , Issue.2 , pp. 140-145
    • Priori, S.G.1
  • 15
    • 77957335813 scopus 로고    scopus 로고
    • Genetics of arrhythmia: Disease pathways beyond ion channels
    • Perez MV, Wheeler M, Ho M, et al. Genetics of arrhythmia: disease pathways beyond ion channels. JCardiovasc Transl Res. 2008;1:155-165.
    • (2008) JCardiovasc Transl Res. , vol.1 , pp. 155-165
    • Perez, M.V.1    Wheeler, M.2    Ho, M.3
  • 16
    • 70350567680 scopus 로고    scopus 로고
    • Genetic evaluation of familial cardiomyopathy
    • Judge DP, Johnson NM. Genetic evaluation of familial cardiomyopathy. JCardiovasc Transl Res. 2008;1:144-154.
    • (2008) JCardiovasc Transl Res. , vol.1 , pp. 144-154
    • Judge, D.P.1    Johnson, N.M.2
  • 17
    • 0025167629 scopus 로고
    • Parental history is an independent risk factor for coronary artery disease: The Framingham Study
    • Myers RH, Kiely DK, Cupples LA, et al. Parental history is an independent risk factor for coronary artery disease: the Framingham Study. Am Heart J. 1990;120:963-969. (Pubitemid 20346165)
    • (1990) American Heart Journal , vol.120 , Issue.4 , pp. 963-969
    • Myers, R.H.1    Kiely, D.K.2    Cupples, L.A.3    Kannel, W.B.4
  • 19
    • 7244245762 scopus 로고    scopus 로고
    • Finishing the euchromatic sequence of the human genome
    • Finishing the euchromatic sequence of the human genome. Nature. 2004;431: 931-945.
    • (2004) Nature. , vol.431 , pp. 931-945
  • 20
    • 79959524146 scopus 로고    scopus 로고
    • A haplotype map ofthe human genome
    • A haplotype map ofthe human genome. Nature. 2005;437:1299-1320.
    • (2005) Nature. , vol.437 , pp. 1299-1320
  • 21
    • 0035895515 scopus 로고    scopus 로고
    • Genomics and medicine: Dissecting human disease in the postgenomic era
    • DOI 10.1126/science.291.5507.1224
    • Peltonen L, McKusick VA. Genomics and medicine. Dissecting human disease in the postgenomic era. Science. 2001;291:1224-1229. (Pubitemid 32173078)
    • (2001) Science , vol.291 , Issue.5507 , pp. 1224-1229
    • Peltonen, L.1    McKusick, V.A.2
  • 22
    • 0028618514 scopus 로고
    • Identification of gene defects by linkage analysis: Use in inherited cardiomyopathies
    • Vosberg HP. Identification of gene defects by linkage analysis: use in inherited cardiomyopathies. Eur Heart J. 1994;15(suppl D):20-23.
    • (1994) Eur Heart J. , vol.15 , Issue.SUPPL. D , pp. 20-23
    • Vosberg, H.P.1
  • 23
    • 0022975030 scopus 로고
    • A DNA probe for the LDL receptor gene is tightly linked to hypercholesterolemia in a pedigree with early coronary disease
    • Leppert MF, Hasstedt SJ, Holm T, et al. A DNA probe for the LDL receptor gene is tightly linked to hypercholesterolemia in a pedigree with early coronary disease. Am JHum Genet. 1986;39:300-306. (Pubitemid 17170832)
    • (1986) American Journal of Human Genetics , vol.39 , Issue.3 , pp. 300-306
    • Leppert, M.F.1    Hasstedt, S.J.2    Holm, T.3
  • 25
    • 0034660559 scopus 로고    scopus 로고
    • Searching for genetic determinants in the new millennium
    • DOI 10.1038/35015718
    • Risch NJ. Searching for genetic determinants in the new millennium. Nature. 2000;405:847-856. (Pubitemid 30407863)
    • (2000) Nature , vol.405 , Issue.6788 , pp. 847-856
    • Risch, N.J.1
  • 26
    • 3142706539 scopus 로고    scopus 로고
    • Meta-analysis: Apolipoprotein E genotypes and risk for coronary heart disease
    • Song Y, Stampfer MJ, Liu S. Meta-analysis: apolipoprotein E genotypes and risk for coronary heart disease. Ann Intern Med. 2004;141:137-147. (Pubitemid 38937836)
    • (2004) Annals of Internal Medicine , vol.141 , Issue.2 , pp. 137-147
    • Song, Y.1    Stampfer, M.J.2    Liu, S.3
  • 27
    • 4344648938 scopus 로고    scopus 로고
    • CD14 and toll-like receptor 4: A link between infection and acute coronary events?
    • DOI 10.1136/hrt.2002.001297
    • Arroyo-Espliguero R, Avanzas P, Jeffery S, et al. CD14 and toll-like receptor 4: a link between infection and acute coronary events? Heart. 2004;90:983-988. (Pubitemid 39127904)
    • (2004) Heart , vol.90 , Issue.9 , pp. 983-988
    • Arroyo-Espliguero, R.1    Avanzas, P.2    Jeffery, S.3    Kaski, J.C.4
  • 28
    • 2942575882 scopus 로고    scopus 로고
    • Role of Toll-like receptor 4 in the initiation and progression of atherosclerotic disease
    • DOI 10.1111/j.1365-2362.2004.01338.x
    • Pasterkamp G, Van Keulen JK, De Kleijn DP. Role ofToll-like receptor 4 in the initiation and progression of atherosclerotic disease. Eur J Clin Invest. 2004;34:328-334. (Pubitemid 38748072)
    • (2004) European Journal of Clinical Investigation , vol.34 , Issue.5 , pp. 328-334
    • Pasterkamp, G.1    Van Keulen, J.K.2    De Kleijn, D.P.V.3
  • 29
    • 34249906772 scopus 로고    scopus 로고
    • Relevance of genetics and genomics for prevention and treatment of cardiovascular disease: A scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Interdisciplinary Working Group
    • DOI 10.1161/CIRCULATIONAHA.107.183679
    • Arnett DK, Baird AE, Barkley RA, et al. Relevance ofgenetics and genomics for prevention and treatment ofcardiovascular disease: a scientific statement from the American Heart Association Council on Epidemiology and Prevention, the Stroke Council, and the Functional Genomics and Translational Biology Inter-disciplinaryWorking Group. Circulation. 2007;115:2878-2901. (Pubitemid 46869676)
    • (2007) Circulation , vol.115 , Issue.22 , pp. 2878-2901
    • Arnett, D.K.1    Baird, A.E.2    Barkley, R.A.3    Basson, C.T.4    Boerwinkle, E.5    Ganesh, S.K.6    Herrington, D.M.7    Hong, Y.8    Jaquish, C.9    McDermott, D.A.10    O'Donnell, C.J.11
  • 30
    • 33644840046 scopus 로고    scopus 로고
    • Genetic susceptibility to coronary artery disease: From promise to progress
    • DOI 10.1038/nrg1805, PII N1805
    • Watkins H, Farrall M. Genetic susceptibility to coronary artery disease: from promise to progress. Nat Rev Genet. 2006;7:163-173. (Pubitemid 43361528)
    • (2006) Nature Reviews Genetics , vol.7 , Issue.3 , pp. 163-173
    • Watkins, H.1    Farrall, M.2
  • 31
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch N, Merikangas K. The future of genetic studies of complex human diseases. Science. 1996;273:1516-1517. (Pubitemid 26301653)
    • (1996) Science , vol.273 , Issue.5281 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 32
    • 13144265739 scopus 로고    scopus 로고
    • Genome-wide association studies: Theoretical and practical concerns
    • DOI 10.1038/nrg1522
    • Wang WY, Barratt BJ, Clayton DG, et al. Genome-wide association studies: theoretical and practical concerns. Nat Rev Genet. 2005;6:109-118. (Pubitemid 40179533)
    • (2005) Nature Reviews Genetics , vol.6 , Issue.2 , pp. 109-118
    • Wang, W.Y.S.1    Barratt, B.J.2    Clayton, D.G.3    Todd, J.A.4
  • 33
    • 40749098064 scopus 로고    scopus 로고
    • Study designs for genome-wide association studies
    • Kraft P, Cox DG. Study designs for genome-wide association studies. Adv Genet. 2008;60:465-504.
    • (2008) Adv Genet. , vol.60 , pp. 465-504
    • Kraft, P.1    Cox, D.G.2
  • 34
    • 2442585696 scopus 로고    scopus 로고
    • The effects of human population structure on large genetic association studies
    • DOI 10.1038/ng1337
    • Marchini J, Cardon LR, Phillips MS, et al. The effects of human population structure on large genetic association studies. Nat Genet. 2004;36:512-517. (Pubitemid 38620038)
    • (2004) Nature Genetics , vol.36 , Issue.5 , pp. 512-517
    • Marchini, J.1    Cardon, L.R.2    Phillips, M.S.3    Donnelly, P.4
  • 35
    • 69249208526 scopus 로고    scopus 로고
    • Gene-environment interactions and obesity-further aspects ofgenomewide association studies
    • Andreasen CH, Andersen G. Gene-environment interactions and obesity-further aspects ofgenomewide association studies. Nutrition. 2009;25:998-1003.
    • (2009) Nutrition. , vol.25 , pp. 998-1003
    • Andreasen, C.H.1    Andersen, G.2
  • 38
    • 4644324638 scopus 로고    scopus 로고
    • A trio family study showing association of the lymphotoxin-alpha N26 (804A) allele with coronary artery disease
    • A trio family study showing association of the lymphotoxin-alpha N26 (804A) allele with coronary artery disease. Eur J Hum Genet. 2004;12:770-774.
    • (2004) Eur J Hum Genet. , vol.12 , pp. 770-774
  • 42
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls
    • Genome-wide association study of 14,000 cases of seven common diseases and 3000 shared controls. Nature. 2007;447:661-678.
    • (2007) Nature. , vol.447 , pp. 661-678
  • 43
    • 55149090262 scopus 로고    scopus 로고
    • A customized genetic approach to the number one killer: Coronary artery disease
    • Roberts R. A customized genetic approach to the number one killer: coronary artery disease. Curr Opin Cardiol. 2008;23:629-633.
    • (2008) Curr Opin Cardiol. , vol.23 , pp. 629-633
    • Roberts, R.1
  • 46
    • 44449176689 scopus 로고    scopus 로고
    • Whole genome analyses suggest ischemic stroke and heart disease share an association with polymorphisms on chromosome 9p21
    • Matarin M, Brown WM, Singleton A, et al. Whole genome analyses suggest ischemic stroke and heart disease share an association with polymorphisms on chromosome 9p21. Stroke. 2008;39:1586-1589.
    • (2008) Stroke. , vol.39 , pp. 1586-1589
    • Matarin, M.1    Brown, W.M.2    Singleton, A.3
  • 48
    • 43049146524 scopus 로고    scopus 로고
    • A HapMap harvest of insights into the genetics of common disease
    • DOI 10.1172/JCI34772
    • Manolio TA, Brooks LD, Collins FS. A HapMap harvest ofinsights into the genetics of common disease. J Clin Invest. 2008;118:1590-1605. (Pubitemid 351632361)
    • (2008) Journal of Clinical Investigation , vol.118 , Issue.5 , pp. 1590-1605
    • Manolio, T.A.1    Brooks, L.D.2    Collins, F.S.3
  • 49
    • 78651323379 scopus 로고    scopus 로고
    • Genetics of myocardial infarction: A progress report
    • Schunkert H, Erdmann J, Samani NJ. Genetics of myocardial infarction: a progress report. Eur Heart J. 2010;31:918-925.
    • (2010) Eur Heart J. , vol.31 , pp. 918-925
    • Schunkert, H.1    Erdmann, J.2    Samani, N.J.3
  • 52
    • 73549097512 scopus 로고    scopus 로고
    • Genetic variants associated with Lp(a) lipoprotein level and coronary disease
    • Clarke R, Peden JF, Hopewell JC, et al. Genetic variants associated with Lp(a) lipoprotein level and coronary disease. NEngl JMed. 2009;361:2518-2528.
    • (2009) NEngl JMed. , vol.361 , pp. 2518-2528
    • Clarke, R.1    Peden, J.F.2    Hopewell, J.C.3
  • 53
    • 67651056502 scopus 로고    scopus 로고
    • Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations
    • Kolz M, Johnson T, Sanna S, et al. Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS Genet. 2009;5:e1000504.
    • (2009) PLoS Genet. , vol.5
    • Kolz, M.1    Johnson, T.2    Sanna, S.3
  • 54
    • 61349177857 scopus 로고    scopus 로고
    • New susceptibility locus for coronary artery disease on chromosome 3q22.3
    • Erdmann J, Grosshennig A, Braund PS, et al. New susceptibility locus for coronary artery disease on chromosome 3q22.3. Nat Genet. 2009;41:280-282.
    • (2009) Nat Genet. , vol.41 , pp. 280-282
    • Erdmann, J.1    Grosshennig, A.2    Braund, P.S.3
  • 55
    • 67650103453 scopus 로고    scopus 로고
    • Genetic variants associated with cardiac structure and function: A meta-analysis and replication of genome-wide association data
    • Vasan RS, Glazer NL, Felix JF, et al. Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data. JAMA. 2009;302:168-178.
    • (2009) JAMA , vol.302 , pp. 168-178
    • Vasan, R.S.1    Glazer, N.L.2    Felix, J.F.3
  • 56
    • 84984932946 scopus 로고    scopus 로고
    • Population genetics - Making sense out of sequence
    • DOI 10.1038/4482
    • Chakravarti A. Population genetics-making sense out of sequence. Nat Genet. 1999;21(suppl 1):56-60. (Pubitemid 29031494)
    • (1999) Nature Genetics , vol.21 , Issue.1 SUPPL. , pp. 56-60
    • Chakravarti, A.1
  • 57
    • 0033592988 scopus 로고    scopus 로고
    • Genetic epidemiology ofsingle-nucleotide polymorphisms
    • Collins A, Lonjou C, Morton NE. Genetic epidemiology ofsingle-nucleotide polymorphisms. Proc Natl Acad Sci USA. 1999;96:15173-15177.
    • (1999) Proc Natl Acad Sci USA. , vol.96 , pp. 15173-15177
    • Collins, A.1    Lonjou, C.2    Morton, N.E.3
  • 58
    • 68949191441 scopus 로고    scopus 로고
    • Genome-based prediction of common diseases: Methodological considerations for future research
    • Janssens AC, van Duijn CM. Genome-based prediction of common diseases: methodological considerations for future research. Genome Med. 2009;1:20.
    • (2009) Genome Med. , vol.1 , pp. 20
    • Janssens, A.C.1    Van Duijn, C.M.2
  • 60
    • 42249084088 scopus 로고    scopus 로고
    • James Watson's genome sequenced at high speed
    • DOI 10.1038/452788b, PII 452788B
    • Wadman M. James Watson's genome sequenced at high speed. Nature. 2008;452:788. (Pubitemid 351550830)
    • (2008) Nature , vol.452 , Issue.7189 , pp. 788
    • Wadman, M.1
  • 61
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome p-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N Engl JMed. 2009;360:354-362.
    • (2009) N Engl JMed. , vol.360 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 62
    • 76349098199 scopus 로고    scopus 로고
    • Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement
    • Sibbing D, Koch W, Gebhard D, et al. Cytochrome 2C19*17 allelic variant, platelet aggregation, bleeding events, and stent thrombosis in clopidogrel-treated patients with coronary stent placement. Circulation. 2010;121:512-518.
    • (2010) Circulation. , vol.121 , pp. 512-518
    • Sibbing, D.1    Koch, W.2    Gebhard, D.3
  • 63
    • 77955425743 scopus 로고    scopus 로고
    • ACCF/AHA clopidogrel clinical alert: Approaches to the FDA "boxed warning": A report of the American College ofCardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association
    • Holmes DR Jr, Dehmer GJ, Kaul S, et al. ACCF/AHA clopidogrel clinical alert: approaches to the FDA "boxed warning": a report of the American College ofCardiology Foundation Task Force on Clinical Expert Consensus Documents and the American Heart Association. Circulation. 2010;122:537-557.
    • (2010) Circulation. , vol.122 , pp. 537-557
    • Holmes Jr., D.R.1    Dehmer, G.J.2    Kaul, S.3
  • 64
    • 49949104757 scopus 로고    scopus 로고
    • SLCO1B1 variants and statin-induced myopathy - A genomewide study
    • Link E, Parish S, Armitage J, et al. SLCO1B1 variants and statin-induced myopathy-a genomewide study. N Engl JMed. 2008;359:789-799.
    • (2008) N Engl JMed. , vol.359 , pp. 789-799
    • Link, E.1    Parish, S.2    Armitage, J.3
  • 65
    • 70449424142 scopus 로고    scopus 로고
    • Genomics and the prospects of existing and emerging therapeutics for cardiovascular diseases
    • Zaiou M, Benachour H, Marteau JB, et al. Genomics and the prospects of existing and emerging therapeutics for cardiovascular diseases. Curr Pharm Des. 2009;15:3193-3206.
    • (2009) Curr Pharm Des. , vol.15 , pp. 3193-3206
    • Zaiou, M.1    Benachour, H.2    Marteau, J.B.3
  • 66
    • 73349110071 scopus 로고    scopus 로고
    • Exome sequencing identifies the cause of a Mendelian disorder
    • Ng SB, Buckingham KJ, Lee C, et al. Exome sequencing identifies the cause of a Mendelian disorder. Nat Genet. 2010;42:30-35.
    • (2010) Nat Genet. , vol.42 , pp. 30-35
    • Ng, S.B.1    Buckingham, K.J.2    Lee, C.3
  • 67
    • 77951799158 scopus 로고    scopus 로고
    • Analysis ofgenetic inheritance in a family quartet by whole-genome sequencing
    • Roach JC, Glusman G, Smit AF, et al. Analysis ofgenetic inheritance in a family quartet by whole-genome sequencing. Science. 2010;328:636-639.
    • (2010) Science. , vol.328 , pp. 636-639
    • Roach, J.C.1    Glusman, G.2    Smit, A.F.3
  • 68
    • 77951589703 scopus 로고    scopus 로고
    • Clinical assessment incorporating a personal genome
    • Ashley EA, Butte AJ, Wheeler MT, et al. Clinical assessment incorporating a personal genome. Lancet. 2010;375:1525-1535.
    • (2010) Lancet. , vol.375 , pp. 1525-1535
    • Ashley, E.A.1    Butte, A.J.2    Wheeler, M.T.3
  • 69
    • 33846603166 scopus 로고    scopus 로고
    • Genetics and heritability of coronary artery disease and myocardial infarction
    • DOI 10.1007/s00392-006-0447-y
    • Mayer B, Erdmann J, Schunkert H. Genetics and heritability of coronary artery disease and myocardial infarction. Clin Res Cardiol. 2007;96:1-7. (Pubitemid 46175364)
    • (2007) Clinical Research in Cardiology , vol.96 , Issue.1 , pp. 1-7
    • Mayer, B.1    Erdmann, J.2    Schunkert, H.3
  • 70
    • 32044468106 scopus 로고    scopus 로고
    • Calculating global risk: The key to intervention
    • DOI 10.1093/eurheartj/sui037, Proceedings of the International Merck Symposium on HDL Raising Beyond LDL-C Reduction: New Paradigms in the Reduction of Cardiovascular Risk
    • Assmann G. Calculating global risk: the key to intervention. Eur Heart J Suppl. 2005;7(suppl F):F9-F14. (Pubitemid 43193780)
    • (2005) European Heart Journal, Supplement , vol.7 , Issue.F
    • Assmann, G.1
  • 71
    • 0043026853 scopus 로고    scopus 로고
    • Genetic evaluation for coronary artery disease
    • DOI 10.1097/01.GIM.0000079364.98247.26
    • Scheuner MT. Genetic evaluation for coronary artery disease. Genet Med. 2003;5:269-285. (Pubitemid 36998685)
    • (2003) Genetics in Medicine , vol.5 , Issue.4 , pp. 269-285
    • Scheuner, M.T.1
  • 72
    • 79951656673 scopus 로고    scopus 로고
    • University ofWashington Seattle, WA: University of Washington Available at Accessed July 4, 2010
    • University ofWashington. Gene Tests. Seattle, WA: University of Washington; 2010. Available at: www.genetests.org. Accessed July 4, 2010.
    • (2010) Gene Tests
  • 73
    • 33748203073 scopus 로고    scopus 로고
    • Genetic testing in cardiac disease: From bench to bedside
    • DOI 10.1038/ncpcardio0654, PII NCPCARDIO0654
    • Cirino AL, Ho CY. Genetic testing in cardiac disease: from bench to bedside. Nat Clin Pract Cardiovasc Med. 2006;3:462-463. (Pubitemid 44307825)
    • (2006) Nature Clinical Practice Cardiovascular Medicine , vol.3 , Issue.9 , pp. 462-463
    • Cirino, A.L.1    Ho, C.Y.2
  • 74
    • 79951614848 scopus 로고    scopus 로고
    • National Society of Genetic Counselors Inc Chicago, IL: National Society of Genetic Counselors Inc Available at Accessed July 4, 2010
    • National Society of Genetic Counselors Inc. NSGC: DNA Banking. Chicago, IL: National Society of Genetic Counselors Inc; 2009. Available at: http://www.nsgc.org/dnabanking.cfm. Accessed July 4, 2010.
    • (2009) NSGC: DNA Banking
  • 76
    • 45549101363 scopus 로고    scopus 로고
    • Keeping pace with the times - The genetic information nondiscrimination act of 2008
    • DOI 10.1056/NEJMp0803964
    • Hudson KL, Holohan MK, Collins FS. Keeping pace with the times-the Genetic Information Nondiscrimination Act of 2008. N Engl J Med. 2008; 358:2661-2663. (Pubitemid 351860857)
    • (2008) New England Journal of Medicine , vol.358 , Issue.25 , pp. 2661-2663
    • Hudson, K.L.1    Holohan, M.K.2    Collins, F.S.3
  • 77
    • 79951636521 scopus 로고    scopus 로고
    • Genova Diagnostics Inc Asheville NC: Genova Diagnostics Inc; Available at Accessed April 26, 2010
    • Genova Diagnostics Inc. Genovations Cardio Genomic Profile. Asheville, NC: Genova Diagnostics Inc; 2008. Available at: http://www.genovadiagnostics. com/files/profile-assets/referenced-materials/Genomics-PatientBrochure.pdf Accessed April 26, 2010.
    • (2008) Genovations Cardio Genomic Profile
  • 78
    • 0036903095 scopus 로고    scopus 로고
    • Shares in the human genome\the future ofpatenting DNA
    • Thomas SM, Hopkins MM, Brady M. Shares in the human genome\the future ofpatenting DNA. Nat Biotechnol. 2008;20:1185-1188.
    • (2008) Nat Biotechnol. , vol.20 , pp. 1185-1188
    • Thomas, S.M.1    Hopkins, M.M.2    Brady, M.3
  • 79
    • 0035257236 scopus 로고    scopus 로고
    • Association study designs for complex diseases
    • DOI 10.1038/35052543
    • Cardon LR, Bell JI. Association study designs for complex diseases. Nat Rev Genet. 2001;2:91-99. (Pubitemid 33674000)
    • (2001) Nature Reviews Genetics , vol.2 , Issue.2 , pp. 91-99
    • Cardon, L.R.1    Bell, J.I.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.