The costs and benefits of hospital MRSA screening

British Journal of Health Care Management

Volumn 17, Issue 2, 2011, Pages 64-71

  Guleri, Achyut ^c   Kehoe, Aidan ^c   Hartley, Julian ^b   Lunt, Barrie ^c   Harper, Nick ^c   Palmer, Ruth ^c   Lickiss, Joe ^c   Mawdsley, Sharon ^a   Jones, Annie ^c  

^a BLACKPOOL VICTORIA HOSPITAL   (United Kingdom)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 79951605308     PISSN: 13580574     EISSN: None     Source Type: Journal    
DOI: 10.12968/bjhc.2011.17.2.64     Document Type: Article

References (37)

1. Aldeyab M, Kearney M, Hughes C et al (2009) Can the use of a rapid polymerase chain screening method decrease the incidence of nosocomial meticillin-resistant Staphylococcus aureus? J Hosp Infect 71(1): 2228
2. Bamra A, Bhandari R, de Wit D, Yates M (2009) The prevalence of methicillin-resistant Staphylococcus aureus (MRSA) carriage in patients presenting to a hospital emergency department. Pathology 41: 609-11
3. Bode L, Kluytmans J, Wertheim H, et al (2010) Preventing surgical-site infections in nasal carriers of Staphylococcus aureus. N Engl J Med 362: 9-17
4. Brenwald NP, Baker N, Oppenheim B (2010) Feasibility study of a real-time PCR test for meticillin-resistant Staphylococcus aureus in a point of care setting. J Hosp Infect 74: 245-9
5. Buhlmann M, Bogli-Stuber K, Droz S, Muhlemann K (2008) Rapid screening for carriage of methicillinresistant Staphylococcus aureus by PCR and associated costs. J Clin Microbiol 46: 2151-4
6. Carroll K (2008) Rapid diagnostics for methicillinresistant Staphylococcus aureus: current status. Mol Diagn Ther 12: 15-24 (Pubitemid 351281696)
7. Coia J, Duckworth G, Edwards D, et al (2006) Guidelines for the control and prevention of methicillin-resistant Staphylococcus aureus (MRSA) in healthcare facilities. J Hosp Infect 63 (Suppl 1): S1-44
8. Cooper B, Stone S, Kibbler C, et al (2003) Systematic review of isolation policies in the hospital management of methicillin-resistant Staphylococcus aureus: a review of the literature with epidemiological and economic modelling. Health Technol Assess 7(39): 1-194
9. Davies S (2010) Health Protection Agency, Department of Health (2008) MRSA screening-operational guidance. http://www.dh.gov.uk/prod-consum-dh/groups/ dh-digitalassets/@dh/@en/documents/digitalasset/ dh-086682.pdf (accessed 21 January 2011)
10. Department of Health (2010) MRSA screening - operational guidance. http://www.dh.gov.uk/ prod-consum-dh/groups/dh-digitalassets/@dh/@ en/documents/digitalasset/dh-115045.pdf (accessed September 28 2010)
11. Flore K, Van den Abeele A, Verschraegen G (2010) Speed of molecular detection techniques for methicillinresistant Staphylococcus aureus admission screening in an acute care hospital. J Hosp Infect 75: 103-6
12. Grundmann H, Aires-de-Sousa M, Boyce J, Tiemersma E (2006) Emergence and resurgence of methicillinresistant Staphylococcus aureus as a public-health threat. Lancet 368: 874-85 (Pubitemid 44308640)
13. Harbarth S, Fankhauser C, Schrenzel J (2008) Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients. JAMA 299: 1149-57 (Pubitemid 351398429)
14. Hardy K, Szczepura A, Davies R (2007) A study of the efficacy and cost-effectiveness of MRSA screening and monitoring on surgical wards using a new, rapid molecular test (EMMS). BMC Health Serv Res 7: 160
15. Health Protection Agency (2008) Surveillance of healthcare associated infections report. http://tinyurl. com/2whu53p (accessed 21 January 2011)
16. Health Protection Agency (2009) MRSA and C. difficile continue to fall. http://www.hpa.org.uk/webw/ HPAweb&HPAwebStandard/HPAweb-C/12525148683 48?p=1231252394302 (accessed 19 September 2009)
17. Health Protection Agency (2010) Results from the madatory surveillance of MRSA bacteraemia. http:// www.hpa.org.uk/Topics/InfectiousDiseases/ InfectoinsAZ/StapylococcusAureus/ EpidemiologicalData/MandatorySurveillance/ staphquarter (accessed 5 August 2010)
18. Herdman M, Wyncoll D, Halligan E, et al (2009) Clinical application of real-time PCR to screening critically ill and emergency-care surgical patients for methicillinresistant Staphylococcus aureus: a quantitative analytical study. J Clin Microbiol 47: 4102-8
19. Jeyaratnam D, Whitty C, Phillips K (2008) Impact of rapid screening tests on acquisition of methicillin resistant Staphylococcus aureus: cluster randomised crossover trial. BMJ 336: 927-30 (Pubitemid 351632018)
20. Jolley S (2008) Assessing patients' knowledge and fears aboout MRSA infection. Nursing Times 104: 32-33
21. Karas J, Enoch D, Eagle H, Emery, M (2009) Random meticillin-resistant Staphylococcus aureus carrier surveillance at a district hospital and the impact of interventions to reduce endemic carriage. J Hosp Infect 71: 327-32
22. Kerremans J, Maaskant J, Verbrugh H et al (2008) Detection of methicillin-resistant Staphylococcus aureus in a low-prevalence setting by polymerase chain reaction with a selective enrichment broth. Diagn Microbiol Infect Dis 61: 396-401 (Pubitemid 351970650)
23. Lehmann L, Alvarez J, Hunfeld K et al (2009) Potential clinical utility of polymerase chain reaction in microbiological testing for sepsis. Crit Care Med 37: 3085-90
24. Lucet J, Regnier B (2010) Screening and decolonization: does methicillin-susceptible Staphylococcus aureus hold lessons for methicillin-resistant S. aureus? Clin Infect Dis 51: 585-90
25. Malhotra-Kumar S et al (2008) Current trends in rapid diagnostics for methicillin-resistant Staphylococcus aureus and glycopeptide-resistant enterococcus species. J Clin Microbiol 46: 1577-87 (Pubitemid 351657198)
26. McGinigle K, Gourlay M, Buchanan I (2008) The use of active surveillance cultures in adult intensive care units to reduce methicillin-resistant Staphylococcus aureusrelated morbidity, mortality, and costs: a systematic review. Clin Infect Dis 46: 1717-25 (Pubitemid 351706769)
27. Millar M (2009) Should we screen low risk patients for meticillin resistant Staphylococcus aureus? BMJ 339: b4035
28. Murthy A, De Angelis G, Pittet D, et al (2010) Costeffectiveness of universal MRSA screening on admission to surgery. Clin Microbiol Infect 16(12):1747-53
29. Nathwani D, Morgan M, Masterton R, et al (2008) Guidelines for UK practice for the diagnosis and management of methicillin-resistant Staphylococcus aureus (MRSA) infections presenting in the community. J Antimicrob Chemother 61: 976-94 (Pubitemid 351545546)
30. Paladino JA (2000) Economic justification of antimicrobial management programs: implications of antimicrobial resistance. Am J Health Syst Pharm 57 (Suppl 2): S10-2
31. Peterson L, Diekema D (2010) To screen or not to Screen for methicillin-resistant Staphylococcus aureus. J Clin Microbiol 48: 683-9
32. Plowman R, Graves N, Griffin M, et al (1999) Socioeconomic Burden of Hospital Acquired Infection. Central Public health Laboratory & London School of Hygiene & Tropical Medicine. London
33. Robicsek A, Beaumont J, Paule S, et al (2008) Universal surveillance for methicillin-resistant Staphylococcus aureus in 3 affiliated hospitals. Ann Intern Med 148: 409-18 (Pubitemid 351665440)
34. Rubio-Terres C, Garau J, Grau S, Martinez-Martinez L (2010) Cost of bacteraemia caused by methicillinresistant vs. methicillin-susceptible Staphylococcus aureus in Spain: a retrospective cohort study. Clin Microbiol Infect 16: 722-8
35. Schulz M, Nonnenmacher C, Mutters R (2009) Costeffectiveness of rapid MRSA screening in surgical patients. Eur J Clin Microbiol Infect Dis 28: 1291-6
36. Sturenburg E (2009) Rapid detection of methicillin resistant Staphylococcus aureus directly from clinical samples: methods, effectiveness and cost considerations. Ger Med Sci 7: Doc06
37. van Hal S, Stark D, Lockwood B, et al (2007) Methicillinresistant Staphylococcus aureus (MRSA) detection: comparison of two molecular methods (IDI-MRSA PCR assay and GenoType MRSA Direct PCR assay) with three selective MRSA agars (MRSA ID, MRSASelect, and CHROMagar MRSA) for use with infection-control swabs. J Clin Microbiol 45: 2486-90 (Pubitemid 47295478)