Procalcitonin as a biomarker for bacterial infections in patients with liver cirrhosis in the emergency department

Academic Emergency Medicine

Volumn 18, Issue 2, 2011, Pages 121-126

  Li, Chih Huang ^a   Yang, Ruey Bing ^c   Pang, Jong Hwei S ^b   Chang, Shy Shin ^a,b   Lin, Chih Chuan ^a,d   Chen, Chien Hsiun ^a,c,d   Chen, Hsien Yi ^a   Chiu, Te Fa ^a,d  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^d CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; PROCALCITONIN; BIOLOGICAL MARKER; CALCITONIN; PROTEIN PRECURSOR;

ADULT; AGED; ARTICLE; BACTEREMIA; BACTERIAL INFECTION; BLOOD CULTURE; CONTROLLED CLINICAL TRIAL; CROSS-SECTIONAL STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; EMERGENCY PATIENT; EMERGENCY WARD; FEMALE; HORMONE BLOOD LEVEL; HUMAN; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SENSITIVITY AND SPECIFICITY; SEPSIS; SINGLE BLIND PROCEDURE; BLOOD; COMPARATIVE STUDY; EMERGENCY HEALTH SERVICE; MIDDLE AGED; RECEIVER OPERATING CHARACTERISTIC; TAIWAN; VALIDATION STUDY;

AGED; BACTERIAL INFECTIONS; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CALCITONIN; CROSS-SECTIONAL STUDIES; EMERGENCY SERVICE, HOSPITAL; FEMALE; HUMANS; LIVER CIRRHOSIS; MALE; MIDDLE AGED; PROTEIN PRECURSORS; ROC CURVE; TAIWAN;

EID: 79951602206     PISSN: 10696563     EISSN: 15532712     Source Type: Journal    
DOI: 10.1111/j.1553-2712.2010.00991.x     Document Type: Article

References (14)

1. Tandon P, Garcia-Tsao G,. Bacterial infections, sepsis, and multiorgan failure in cirrhosis. Semin Liver Dis. 2008; 28: 26-42. (Pubitemid 351326531)
2. Foreman MG, Mannino DM, Moss M,. Cirrhosis as a risk factor for sepsis and death: analysis of the National Hospital Discharge Survey. Chest. 2003; 124: 1016-20. (Pubitemid 37123324)
3. Dhainaut JF, Claessens YE, Janes J, et al., Underlying disorders and their impact on the host response to infection. Clin Infect Dis. 2005; 41: S481-9. (Pubitemid 41598309)
4. Wiest R, Garcia-Tsao G,. Bacterial translocation (BT) in cirrhosis. Hepatology. 2005; 41: 422-33. (Pubitemid 40289486)
5. Levy MM, Fink MP, Marshall JC, et al., 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med. 2003; 31: 1250-6. (Pubitemid 36444440)
6. Assicot M, Gendrel D, Carsin H, et al., High serum procalcitonin concentrations in patients with sepsis and infection. Lancet. 1993; 341: 515-8. (Pubitemid 23066085)
7. Simon L, Gauvin F, Amre DK, et al., Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis. 2004; 39: 206-17. (Pubitemid 38971491)
8. Bota DP, Van Nuffelen M, Zakariah AN, et al., Serum levels of C-reactive protein and procalcitonin in critically ill patients with cirrhosis of the liver. J Lab Clin Med. 2005; 146: 347-51. (Pubitemid 41712021)
9. Connert S, Stremmel W, Elsing C,. Procalcitonin is a valid marker of infection in decompensated cirrhosis. Z Gastroenterol. 2003; 41: 165-70. (Pubitemid 36313736)
10. Bossuyt PM, Reitsma JB, Bruns DE, et al., Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative. BMJ. 2003; 326 (7379): 41-4. (Pubitemid 36110721)
11. Morrell M, Fraser VJ, Kollef MH,. Delaying the empiric treatment of Candida bloodstream infection until positive blood culture results are obtained: a potential risk factor for hospital mortality. Antimicrob Agents Chemother. 2005; 49: 3640-5. (Pubitemid 41233011)
12. Rivers E, Nguyen B, Havstad S, et al., Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001; 345: 1368-77.
13. Tsiakalos A, Karatzaferis A, Ziakas P, et al., Acute-phase proteins as indicators of bacterial infection in patients with cirrhosis. Liver Int. 2009; 29 (10): 1538-42.
14. Lin ZY, Chuang WL, Dai CY, et al., Clinical application of serum C-reactive protein measurement in the detection of bacterial infection in patients with liver cirrhosis. Kaohsiung J Med Sci. 2002; 18: 121-6.