Clinically silent chromaffin-cell tumors: Tumor characteristics and long-term prognosis in patients with incidentally discovered pheochromocytomas

Journal of Endocrinological Investigation

Volumn 33, Issue 10, 2010, Pages 739-744

  Grozinsky Glasberg, S ^a,b   Szalat, A ^c   Benbassat, C A ^a,b   Gorshtein, A ^a,b   Weinstein, R ^a,b   Hirsch, D ^a,b   Shraga Slutzky, I ^a   Tsvetov, G ^a,b   Gross, D J ^c   Shimon, I ^a,b  

^a RABIN MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

Author keywords

Catecholamines; Chromogranin A; Incidental; Paragangliomas; Pheochromocytomas

Indexed keywords

ADRENALIN; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHROMOGRANIN A; DOPAMINE; NORADRENALIN; NORMETADRENALIN; VANILMANDELIC ACID;

ADRENALIN BLOOD LEVEL; ADULT; ARTICLE; BLOOD PRESSURE REGULATION; CANCER INVASION; CANCER SURGERY; CHROMAFFIN CELL; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DOPAMINE URINE LEVEL; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; HYPERTENSION; INCIDENTAL FINDING; MALE; MULTICENTER STUDY; NORADRENALIN BLOOD LEVEL; PHEOCHROMOCYTOMA; PROGNOSIS; PROTEIN BLOOD LEVEL; RETROSPECTIVE STUDY; TUMOR LOCALIZATION;

EID: 79951590847     PISSN: 03914097     EISSN: 17208386     Source Type: Journal    
DOI: 10.1007/bf03346680     Document Type: Article

References (26)

1. Grumbach MM, Biller BM, Braunstein GD, et al. Management of the clinically inapparent adrenal mass ("incidentaloma"). Ann Intern Med 2003, 138: 424-9. (Pubitemid 36262654)
2. O'Riordain DS, Young WF Jr, Grant CS, Carney JA, van Heerden JA. Clinical spectrum and outcome of functional extraadrenal paraganglioma. World J Surg 1996, 20: 916-21.
3. Maher ER, Eng C. The pressure rises: update on the genetics of phaeochromocytoma. Hum Mol Genet 2002, 11: 2347-54. (Pubitemid 35174697)
4. Astuti D, Morris M, Krona C, et al. Investigation of the role of SD-HB inactivation in sporadic phaeochromocytoma and neuroblastoma. Br J Cancer 2004, 91: 1835-41. (Pubitemid 39664973)
5. Eisenhofer G, Bornstein SR, Brouwers FM, et al. Malignant pheochromocytoma: current status and initiatives for future progress. Endocr Relat Cancer 2004, 11: 423-36. (Pubitemid 39331275)
6. Bravo EL, Tagle R. Pheochromocytoma: state-of-the-art and future prospects. Endocr Rev 2003, 24: 539-53.
7. Scholz T, Schulz C, Klose S, Lehnert H. Diagnostic management of benign and malignant pheochromocytoma. Exp Clin Endocrinol Diabetes 2007, 115: 155-9. (Pubitemid 46640281)
8. Amar L, Servais A, Gimenez-Roqueplo AP, Zinzindohoue F, Chatellier G, Plouin PF. Year of diagnosis, features at presentation, and risk of recurrence in patients with pheochromocytoma or secreting paraganglioma. J Clin Endocrinol Metab 2005, 90: 2110-6. (Pubitemid 40586247)
9. Tsvetov G, Shimon I, Benbassat C. Adrenal incidentaloma: clinical characteristics and comparison between patients with and without extraadrenal malignancy. J Endocrinol Invest 2007, 30: 647-52. (Pubitemid 350104093)
10. Beard CM, Sheps SG, Kurland LT, Carney JA, Lie JT. Occurrence of pheochromocytoma in Rochester, Minnesota, 1950 through 1979. Mayo Clin Proc 1983, 58: 802-4.
11. Benn DE, Gimenez-Roqueplo AP, Reilly JR, et al. Clinical presentation and penetrance of pheochromocytoma/paraganglioma syndromes. J Clin Endocrinol Metab 2006, 91: 827-36. (Pubitemid 43357746)
12. Ilias I, Pacak K. Anatomical and functional imaging of metastatic pheochromocytoma. Ann N Y Acad Sci 2004, 1018: 495-504. (Pubitemid 38951445)
13. Kowalski J, Henze M, Schuhmacher J, Macke HR, Hofmann M, Haberkom U. Evaluation of positron emission tomography imaging using [68Ga]-DOTA-D Phe(1)-Tyr(3)-Octreotide in comparison to [111In]-DTPAOC SPECT. First results in patients with neuroendocrine tumors. Mol Imaging Biol 2003, 5: 42-8.
14. Noshiro T, Shimizu K, Watanabe T, et al. Changes in clinical features and long-term prognosis in patients with pheochromocytoma. Am J Hypertens 2000, 13: 35-43. (Pubitemid 30103862)
15. Smithwick RH, Greer WE. Pheochromocytoma; a discussion of symptoms, signs and procedures of diagnostic value. N Engl J Med 1950, 242: 252-7.
16. DeLellis RA, Eng C, Heitz PU, Lloyd RV. (2004) World Health Organization classification of tumours, pathology and genetics of tumours of endocrine organs. IARC, Lyon, 2009.
17. Kopetschke R, Slisko M, Kilisli A, et al. Frequent incidental discovery of phaeochromocytoma: data from a German cohort of 201 phaeochromocytoma. Eur J Endocrinol 2009, 161: 355-61.
18. Motta-Ramirez GA, Remer EM, Herts BR, Gill IS, Hamrahian AH. Comparison of CT findings in symptomatic and incidentally discovered pheochromocytomas. AJR Am J Roentgenol 2005, 185: 684-8.
19. Miyajima A, Nakashima J, Baba S, Tachibana M, Nakamura K, Murai M. Clinical experience with incidentally discovered pheochromocytoma. J Urol 1997, 157: 1566-8. (Pubitemid 27171725)
20. Kirshtein B, Pagliarello G, Yelle JD, Poulin EC. Incidence of pheochromocytoma in trauma patients during the management of unrelated illness: a retrospective review. Int J Surg 2007, 5: 332-5. (Pubitemid 47540001)
21. Crout JR, Sjoerdsma A. Turnover and metabolism of catecholamines in patients with pheochromocytoma. J Clin Invest 1964, 43: 94-102.
22. Baguet JP, Hammer L, Mazzuco TL, et al. Circumstances of discovery of phaeochromocytoma: a retrospective study of 41 consecutive patients. Eur J Endocrinol 2004, 150: 681-6. (Pubitemid 38786538)
23. Feldman JM, Blalock JA, Zern RT, Wells SA Jr. The relationship between enzyme activity and the catecholamine content and secretion of pheochromocytomas. J Clin Endocrinol Metab 1979, 49: 445-51. (Pubitemid 10188193)
24. Eisenhofer G, Goldstein DS, Walther MM, et al. Biochemical diagnosis of pheochromocytoma: how to distinguish true- from false-positive test results. J Clin Endocrinol Metab 2003, 88: 2656-66. (Pubitemid 36724439)
25. Solorzano CC, Lew JI, Wilhelm SM, et al. Outcomes of pheochromocytoma management in the laparoscopic era. Ann Surg Oncol 2007, 14: 3004-10. (Pubitemid 47460651)
26. Wilhelm SM, Prinz RA, Barbu AM, Onders RP, Solorzano CC. Analysis of large versus small pheochromocytomas: operative approaches and patient outcomes. Surgery 2006, 140: 553-9.