Protective effect of the aqueous extract of Momordica charantia leaves on gentamicin induced nephrotoxicity in rats

International Journal of PharmTech Research

Volumn 3, Issue 1, 2011, Pages 553-555

  Chaware, V J ^a   Chaudhary, B P ^a   Vaishnav, M K ^a   Biyani, K R ^a  

^a Anuradha College of Pharmacy   (India)

Author keywords

Gentamicin induced nephrotoxicity; Momordica charantia leaves; Nephrotoxicity; Rats

Indexed keywords

CREATININE; GENTAMICIN; MOMORDICA CHARANTIA EXTRACT; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFECT; INTOXICATION; MOMORDICA CHARANTIA; NEPHROTOXICITY; NONHUMAN; PLANT LEAF; RAT; TREATMENT DURATION; UREA BLOOD LEVEL; UREA NITROGEN BLOOD LEVEL;

EID: 79951573885     PISSN: None     EISSN: 09744304     Source Type: Journal    
DOI: None     Document Type: Article

References (7)

1. Chambers, H.F., 2001. Antimicrobial Agents: The Amino glycosides. In: Hardman, J.G., Limbird, L.E., Goodman and Gilman's, A.G., (Eds.), The Pharmacology Basis of Therapeutics, 10th ed., McGraw-Hill Medical publishing, New York, USA, pp.1219-1238.
2. Apple, G.B.,1982.Aminoglycoside nephrotoxicity: Physiological study of the site of Nephrone damage. In: Whelton, A., Neu, H.C.(Eds.), The Amino glycoside: Microbiology, Clinical use, and Toxicity. Marcel Dekker Inc., New York, USA, pp.269-282.
3. Barry, M.B., 2000.Toxic Nephropathies. The Kidneys, vol. 2, W.B. Saunder Company Philadelphia, pp. 3-67.
4. Emeigh Hart, S.G.E., Beierssehmit, W.P., Wyand, D.S., Khair Allah, C.A., Cohen, S.D.,1994. Acetoamino-phen nephrotoxicity in CD-1mice.l.Evidence of a role for in situ activation in selective covalent binding and toxicity. Toxicology and applied pharmacology 126, 267-275.
5. Cojocel, C., 1997.Aminoglycoside nephrotoxicity. In: sipes, I.G., McQueen, C.A., Gandolfi, A.J.,(Eds.), Comprehensive Toxicology, Vol.7, Elsevier, Oxford, pp.495-524.
6. Devpriya, S., Shyamaladevin, C.S., 1999. Protective effect of quercetinin in cisplatin induced cell injury in rat kidney. Indian Journal of Pharmacology, 31, pp.422.
7. Adelman, R.D, Siangler, W.L., Beason, F., Ishizaki, G., Conselman, G.M., 1981. Frusemide enhancement of nettimicin nephrotoxicity in dogs. Journal of Antimicrobial and Chemotherapy, pp.431-435.