Simple and rapid spectrophotometric estimation of gemifloxacin mesylate in bulk and tablet formulations

International Journal of PharmTech Research

Volumn 3, Issue 1, 2011, Pages 133-135

  Charan, Danta Chhanda ^a   Satyabrata, Sahu ^a  

^a Dadhichi College of Pharmacy   (India)

Author keywords

Gemifloxacin mesylate; Method validation; Ultraviolet spectrophotometry

Indexed keywords

ACID; GEMIFLOXACIN;

ACCURACY; ARTICLE; CALIBRATION; CORRELATION COEFFICIENT; DRUG DOSAGE FORM; DRUG QUALITY; DRUG SCREENING; DRUG SENSITIVITY; DRUG STRUCTURE; HUMAN; INSTRUMENT VALIDATION; LIMIT OF DETECTION; LIMIT OF QUANTITATION; NONHUMAN; TABLET FORMULATION; ULTRAVIOLET SPECTROPHOTOMETRY;

EID: 79951569223     PISSN: None     EISSN: 09744304     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Wilson R., Schentag J.J., Ball P., Mandell L., A comparison of gemifloxacin and clarithromycin in acute exacerbations of chronic bronchitis and long-term clinical outcomes, Clin. Ther. 2002, 40, 639-652.
2. Lowe M.N., Lamb H.M., Gemifloxacin, Drugs, 59(May), 2000, 1137-1147.
3. Krishna M.V., Sankar D.G., Utility of σ and π acceptors for the spectrophotometric determination of gemifloxacin mesylate in pharmaceutical formulations, E. J. Chem. 5 (3), 2008, 493.
4. Lomaestro B.M., Gemifloxacin: Broad spectrum oral quinolone for treatment of respiratory and urinary tract infections, Formulary, 35(Dec), 2000, 961-968.
5. Doyle E., Fowles S.E., McDonnell D.F., McCarthy R., White S.A., Rapid determination of gemifloxacin in human plasma by high performance liquid chromatography-tandem mass spectrometry, J. Chromatogr. B 2000, 746, 191-198.
6. Rote A.R., Pingle S.P., Reverse phase-HPLC and HPTLC methods for determination of gemifloxacin mesylate in human plasma, J. Chromatogr. B 2009, 877, 3719-3723.
7. Cho S.I., Shim J., Kim M.S., Kim Y.K., Chung D.S., Online sample cleanup and chiral separation of gemifloxacin in a urinary solution using chiral crown ether as a chiral selector in microchip electrophoresis, J. Chromatogr. A 2004, 1055, 241-245.
8. Vinodhini C., Chitras K., Annie A.S.S., Marbaniang I., Singh A.K., Ashok D., Reddy C.U., Determination of gemifloxacin in tablets by reverse phase high performance liquid chromatography, Indian Drugs, 2009, 46, 71-73.
9. Krishna M.V., Sankar D.G., Spectrophotometric determination of Gemifloxacin mesylate in pharmaceutical formulation through ion pair complex formation, E. J. Chem. 5 (3), 2008, 515-520.