Decisional conflict and the disposition of frozen embryos: Implications for informed consent

Human Reproduction

Volumn 26, Issue 3, 2011, Pages 646-654

  Lyerly, A D ^a,b   Nakagawa, S ^c   Kuppermann, M ^c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

cryopreserved embryos; embryo disposition; ethics; informed consent; stem cell research

Indexed keywords

ADULT; ARTICLE; CONFLICT; CRYOPRESERVATION; DECISION MAKING; EMBRYO CULTURE; EMBRYO DISPOSITION; FEMALE; FREEZE THAWING; FROZEN EMBRYO; HUMAN; INFORMED CONSENT; MAJOR CLINICAL STUDY; MORALITY; OUTCOME ASSESSMENT; PREGNANCY;

EID: 79951567566     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/deq368     Document Type: Article

References (19)

1. Brehaut J, O'Connor A, Wood TJ, Hack TF, Siminoff L, Gordon E, Feldman-Stewart D. Validation of a decision regret scale. Med Decis Making 2003;23:281-292. (Pubitemid 36899094)
2. De Lacey S. Parent identity and 'virtual' children: why patients discard rather than donate unused embryos. Hum Reprod 2005; 20:1661-1669.
3. De Lacey S. Decisions for the fate of frozen embryos: fresh insights into patients' thinking and their rationales for donating or discarding embryos. Hum Reprod 2007;22:1751-1758.
4. Ethics Committee of the American College of Obstetricians and Gynecologists. Committee Opinion #439: Informed Consent. Washington DC, USA: American College of Obstetricians and Gynecologists, 2009.
5. Faden R, Beauchamp T. A History and Theory of Informed Consent. New York, USA: Oxford University Press, 1987.
6. Fuscaldo G, Russell S, Gillam L. How to facilitate decisions about surplus embryos: patients' views. Hum Reprod 2007;22:3129-3138. (Pubitemid 351696786)
7. Hudson K, Scott J, Faden R. Values in Conflict: Public Attitudes on Stem Cell Research. Washington, DC, USA: Genetics and Public Policy Center, 2005.
8. Lanzendorf S, Ratts V, Keller S, Odem R. Disposition of cryopreserved embryos by infertility patients desiring to discontinue storage. Fertil Steril 2009;93:486-489.
9. Lyerly AD, Faden RR. Willingness to donate frozen embryos for stem cell research. Science 2007;317:46-47. (Pubitemid 47056438)
10. Lyerly AD, Steinhauser K, Namey E, Tulsky JA, Cook-Deegan R, Sugarman J, Walmer D, Faden R, Wallach E. Factors that affect infertility patients' decisions about disposition of frozen embryos. Fertil Steril 2006;85:1623-1630. (Pubitemid 43816419)
11. Lyerly A, Steinhauser K, Voils C, Namey E, Alexander C, Bankowski B, Cook-Deegan R, Dodson W, Jungheim E, Gates E et al. Fertility patients' views about frozen embryo disposition: results of a multi-institutional U.S. survey. Fertil Steril 2010;93:499-509.
12. McMahon C, Gibson F, Cohen J, Leslie G, Tennant C, Saunders D. Mothers conceiving through in vitro fertilization: siblings, setbacks, and embryo dilemmas. Reprod Technol 2000;10:131-135.
13. Nachtigall R, Mac Dougall K, Harrington J, Duff J, Lee M, Becker G. How couples who have undergone in vitro fertilization decide what to do with surplus frozen embryos. Fertil Steril 2009;92:2094-2096.
14. Nachtigall R, Mac Dougall K, Lee M, Harrington J, Becker G. What do patients want? Expectations and perceptions of IVF clinic information and support regarding frozen embryo disposition. Fertil Steril 2010; epub Mar 23. National Institutes of Health Guidelines for Stem Cell Research. 2009 (accessed at http://stemcells.nih.gov/policy/2009guidelines.htm.).
15. Newton CR, Fisher J, Feyles V, Tekpetey F, Hughes L, Isacsson D. Changes in patient preferences in the disposal of cryopreserved embryos. Hum Reprod 2007;22:3124-3128. (Pubitemid 351696773)
16. O'Connor A. Validation of a decisional conflict scale. Med Decis Making 1995;15:25-30.
17. O'Connor A, Bennett C, Stacey D, Barry M, Col NF, Eden KB, Entwistle VA, Fiset V, Holmes-Rovner M, Khangura S et al. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev 2009;10:CD001431.
18. User Manual: Decisional Conflict Scale 2006 (accessed at http://decisionaid.ohri.ca/docs/develop/User-Manuals/UM-Decisional- Conflict.pdf).
19. Willis G. Cognitive Interviewing. Thousand Oaks, CA, USA: Sage Publications, 2005.