The Incidental Pancreatic Cyst

Radiologic Clinics of North America

Volumn 49, Issue 2, 2011, Pages 349-359

  Megibow, Alec J ^a   Baker, Mark E ^b   Gore, Richard M ^c   Taylor, Andrew ^d  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c NORTHSHORE UNIVERSITY HEALTHSYSTEM   (United States)

^d VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Incidental finding; Management; MDCT; MRI; Pancreatic cyst

Indexed keywords

CONSERVATIVE TREATMENT; CYSTADENOMA; DIAGNOSTIC ACCURACY; ECHOGRAPHY; FOLLOW UP; HUMAN; IMAGE ANALYSIS; INCIDENTAL FINDING; INTRADUCTAL PAPILLARY MUCINOUS TUMOR; MAGNETIC RESONANCE CHOLANGIOPANCREATOGRAPHY; MEDICAL DECISION MAKING; MULTIDETECTOR COMPUTED TOMOGRAPHY; NUCLEAR MAGNETIC RESONANCE IMAGING; PANCREAS CYST; PANCREAS RESECTION; PRIORITY JOURNAL; REVIEW; SENSITIVITY AND SPECIFICITY; TUMOR VOLUME; WATCHFUL WAITING;

DIAGNOSIS, DIFFERENTIAL; HUMANS; INCIDENTAL FINDINGS; MAGNETIC RESONANCE IMAGING; PANCREATIC CYST; TOMOGRAPHY, X-RAY COMPUTED; WATCHFUL WAITING;

EID: 79951559726     PISSN: 00338389     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rcl.2010.10.008     Document Type: Review

References (55)

1. Spinelli K.S., Fromwiller T.E., Daniel R.A., et al. Cystic pancreatic neoplasms: observe or operate. Ann Surg 2004, 239(5):651-657. [discussion: 657-9].
2. Laffan T.A., Horton K.M., Klein A.P., et al. Prevalence of unsuspected pancreatic cysts on MDCT. AJR Am J Roentgenol 2008, 191(3):802-807.
3. Zhang X.M., Mitchell D.G., Dohke M., et al. Pancreatic cysts: depiction on single-shot fast spin-echo MR images. Radiology 2002, 223(2):547-553.
4. Lee K.S., Sekhar A., Rofsky N.M., et al. Prevalence of incidental pancreatic cysts in the adult population on MR imaging. Am J Gastroenterol 2010, 2010:30.
5. Simeone D.M. SSAT/AGA/ASGE state of the art conference on cystic neoplasms of the pancreas. J Gastrointest Surg 2008, 12(8):1475-1477.
6. Adsay N.V. Cystic neoplasia of the pancreas: pathology and biology. J Gastrointest Surg 2008, 12(3):401-404.
7. Parra-Herran C.E., Garcia M.T., Herrera L., et al. Cystic lesions of the pancreas: clinical and pathologic review of cases in a five year period. JOP 2010, 11(4):358-364.
8. Procacci C., Graziani R., Bicego E., et al. Serous cystadenoma of the pancreas: report of 30 cases with emphasis on the imaging findings. J Comput Assist Tomogr 1997, 21(3):373-382.
9. Procacci C., Biasiutti C., Carbognin G., et al. Characterization of cystic tumors of the pancreas: CT accuracy. J Comput Assist Tomogr 1999, 23(6):906-912.
10. Rautou P.E., Levy P., Vullierme M.P., et al. Morphologic changes in branch duct intraductal papillary mucinous neoplasms of the pancreas: a midterm follow-up study. Clin Gastroenterol Hepatol 2008, 6(7):807-814.
11. Procacci C., Carbognin G., Accordini S., et al. CT features of malignant mucinous cystic tumors of the pancreas. Eur Radiol 2001, 11(9):1626-1630.
12. Choi J.Y., Kim M.J., Lee J.Y., et al. Typical and atypical manifestations of serous cystadenoma of the pancreas: imaging findings with pathologic correlation. AJR Am J Roentgenol 2009, 193(1):136-142.
13. Cohen-Scali F., Vilgrain V., Brancatelli G., et al. Discrimination of unilocular macrocystic serous cystadenoma from pancreatic pseudocyst and mucinous cystadenoma with CT: initial observations. Radiology 2003, 228(3):727-733.
14. Sahani D.V., Kadavigere R., Saokar A., et al. Cystic pancreatic lesions: a simple imaging-based classification system for guiding management. Radiographics 2005, 25(6):1471-1484.
15. Walsh R.M., Henderson J.M., Vogt D.P., et al. Prospective preoperative determination of mucinous pancreatic cystic neoplasms. Surgery 2002, 132(4):628-633. [discussion: 633-4].
16. Takeshita K., Kutomi K., Takada K., et al. Unusual imaging appearances of pancreatic serous cystadenoma: correlation with surgery and pathologic analysis. Abdom Imaging 2005, 15:15.
17. Waters J.A., Schmidt C.M., Pinchot J.W., et al. CT vs MRCP: optimal classification of IPMN type and extent. J Gastrointest Surg 2008, 12(1):101-109.
18. Correa-Gallego C., Ferrone C.R., Thayer S.P., et al. Incidental pancreatic cysts: do we really know what we are watching?. Pancreatology 2010, 10(2-3):144-150.
19. Fernandez-del Castillo C., Targarona J., Thayer S.P., et al. Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg 2003, 138(4):427-433. [discussion: 433-4].
20. Walsh R.M., Vogt D.P., Henderson J.M., et al. Management of suspected pancreatic cystic neoplasms based on cyst size. Surgery 2008, 144(4):677-684. [discussion: 684-5].
21. Lahav M., Maor Y., Avidan B., et al. Nonsurgical management of asymptomatic incidental pancreatic cysts. Clin Gastroenterol Hepatol 2007, 5(7):813-817.
22. Sahani D.V., Saokar A., Hahn P.F., et al. Pancreatic cysts 3 cm or smaller: how aggressive should treatment be?. Radiology 2006, 238(3):912-919.
23. Tanaka M., Chari S., Adsay V., et al. International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas. Pancreatology 2006, 6(1-2):17-32.
24. Walsh R.M., Vogt D.P., Henderson J.M., et al. Natural history of indeterminate pancreatic cysts. Surgery 2005, 138(4):665-670. [discussion: 670-1].
25. Allen P.J., D'Angelica M., Gonen M., et al. A selective approach to the resection of cystic lesions of the pancreas: results from 539 consecutive patients. Ann Surg 2006, 244(4):572-582.
26. Edirimanne S., Connor S.J. Incidental pancreatic cystic lesions. World J Surg 2008, 32(9):2028-2037.
27. Brounts L.R., Lehmann R.K., Causey M.W., et al. Natural course and outcome of cystic lesions in the pancreas. Am J Surg 2009, 197(5):619-622. [discussion: 622-3].
28. Bassi C., Sarr M.G., Lillemoe K.D., et al. Natural history of intraductal papillary mucinous neoplasms (IPMN): current evidence and implications for management. J Gastrointest Surg 2008, 12(4):645-650.
29. Gomez D., Rahman S.H., Wong L.F., et al. Predictors of malignant potential of cystic lesions of the pancreas. Eur J Surg Oncol 2008, 34(8):876-882.
30. Ceppa E.P., De la Fuente S.G., Reddy S.K., et al. Defining criteria for selective operative management of pancreatic cystic lesions: does size really matter?. J Gastrointest Surg 2010, 14(2):236-244.
31. Goh B.K., Tan Y.M., Cheow P.C., et al. Cystic lesions of the pancreas: an appraisal of an aggressive resectional policy adopted at a single institution during 15 years. Am J Surg 2006, 192(2):148-154.
32. Handrich S.J., Hough D.M., Fletcher J.G., et al. The natural history of the incidentally discovered small simple pancreatic cyst: long-term follow-up and clinical implications. AJR Am J Roentgenol 2005, 184(1):20-23.
33. Lee S.H., Shin C.M., Park J.K., et al. Outcomes of cystic lesions in the pancreas after extended follow-up. Dig Dis Sci 2007, 52(10):2653-2659.
34. Salvia R., Crippa S., Falconi M., et al. Branch-duct intraductal papillary mucinous neoplasms of the pancreas: to operate or not to operate?. Gut 2007, 56(8):1086-1090.
35. Bassi C., Crippa S., Salvia R. Intraductal papillary mucinous neoplasms (IPMNs): is it time to (sometimes) spare the knife?. Gut 2008, 57(3):287-289.
36. Javle M., Shah P., Yu J., et al. Cystic pancreatic tumors (CPT): predictors of malignant behavior. J Surg Oncol 2007, 95(3):221-228.
37. Manfredi R., Graziani R., Motton M., et al. Main pancreatic duct intraductal papillary mucinous neoplasms: accuracy of MR imaging in differentiation between benign and malignant tumors compared with histopathologic analysis. Radiology 2009, 253(1):106-115.
38. Sodickson A., Mortele K.J., Barish M.A., et al. Three-dimensional fast-recovery fast spin-echo MRCP: comparison with two-dimensional single-shot fast spin-echo techniques. Radiology 2006, 238(2):549-559.
39. Carbognin G., Pinali L., Girardi V., et al. Collateral branches IPMTs: secretin-enhanced MRCP. Abdom Imaging 2007, 32(3):374-380.
40. Das A., Wells C.D., Nguyen C.C. Incidental cystic neoplasms of pancreas: what is the optimal interval of imaging surveillance?. Am J Gastroenterol 2008, 103(7):1657-1662.
41. Taouli B., Vilgrain V., Vullierme M.P., et al. Intraductal papillary mucinous tumors of the pancreas: helical CT with histopathologic correlation. Radiology 2000, 217(3):757-764.
42. Lee C.J., Scheiman J., Anderson M.A., et al. Risk of malignancy in resected cystic tumors of the pancreas < or =3 cm in size: is it safe to observe asymptomatic patients? A multi-institutional report. J Gastrointest Surg 2008, 12(2):234-242.
43. Weinberg B.M., Spiegel B.M., Tomlinson J.S., et al. Asymptomatic pancreatic cystic neoplasms: maximizing survival and quality of life using Markov-based clinical nomograms. Gastroenterology 2010, 138(2):531-540.
44. Walsh R.M., Zuccaro G., Dumot J.A., et al. Predicting success of endoscopic aspiration for suspected pancreatic cystic neoplasms. JOP 2008, 9(5):612-617.
45. Brugge W.R., Lewandrowski K., Lee-Lewandrowski E., et al. Diagnosis of pancreatic cystic neoplasms: a report of the cooperative pancreatic cyst study. Gastroenterology 2004, 126(5):1330-1336.
46. Linder J.D., Geenen J.E., Catalano M.F. Cyst fluid analysis obtained by EUS-guided FNA in the evaluation of discrete cystic neoplasms of the pancreas: a prospective single-center experience. Gastrointest Endosc 2006, 64(5):697-702.
47. van der Waaij L.A., van Dullemen H.M., Porte R.J. Cyst fluid analysis in the differential diagnosis of pancreatic cystic lesions: a pooled analysis. Gastrointest Endosc 2005, 62(3):383-389.
48. Thosani N., Thosani S., Qiao W., et al. Role of EUS-FNA-based cytology in the diagnosis of mucinous pancreatic cystic lesions: a systematic review and meta-analysis. Dig Dis Sci 2010, 55(10):2756-2766.
49. Salvia R., Crippa S., Partelli S., et al. Pancreatic cystic tumours: when to resect, when to observe. Eur Rev Med Pharmacol Sci 2010, 14(4):395-406.
50. Macari M., Lee T., Kim S., et al. Is gadolinium necessary for MRI follow-up evaluation of cystic lesions in the pancreas? Preliminary results. AJR Am J Roentgenol 2009, 192(1):159-164.
51. Maimone S., Agrawal D., Pollack M.J., et al. Variability in measurements of pancreatic cyst size among EUS, CT, and magnetic resonance imaging modalities. Gastrointest Endosc 2010, 71(6):945-950.
52. Pauls S., Kurschner C., Dharaiya E., et al. Comparison of manual and automated size measurements of lung metastases on MDCT images: potential influence on therapeutic decisions. Eur J Radiol 2008, 66(1):19-26.
53. Tada M., Kawabe T., Arizumi M., et al. Pancreatic cancer in patients with pancreatic cystic lesions: a prospective study in 197 patients. Clin Gastroenterol Hepatol 2006, 4(10):1265-1270.
54. Uehara H., Nakaizumi A., Ishikawa O., et al. Development of ductal carcinoma of the pancreas during follow-up of branch duct intraductal papillary mucinous neoplasm of the pancreas. Gut 2008, 57(11):1561-1565.
55. Takaori K., Kobashi Y., Matsusue S., et al. Clinicopathological features of pancreatic intraepithelial neoplasias and their relationship to intraductal papillary-mucinous tumors. J Hepatobiliary Pancreat Surg 2003, 10(2):125-136.