Treatment-related deaths in second complete remission in childhood acute myeloid leukaemia

British Journal of Haematology

Volumn 152, Issue 5, 2011, Pages 623-630

  Molgaard Hansen, Lene ^a   Möttönen, Merja ^b   Glosli, Heidi ^c   Jónmundsson, Gudmundur K ^d   Abrahamsson, Jonas ^e   Hasle, Henrik ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b OULU UNIVERSITY HOSPITAL   (Finland)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

^d LANDSPITALI UNIVERSITY HOSPITAL   (Iceland)

^e QUEEN SILVIA CHILDREN'S HOSPITAL   (Sweden)

Author keywords

Acute myeloid leukaemia; Children; Infection; Relapse; Treatment related mortality

Indexed keywords

AMSACRINE; ANTHRACYCLINE; CYTARABINE; DOXORUBICIN; ETOPOSIDE; FLUDARABINE; GRANULOCYTE COLONY STIMULATING FACTOR; METHOTREXATE; TIOGUANINE;

ACUTE GRANULOCYTIC LEUKEMIA; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CANCER COMBINATION CHEMOTHERAPY; CANCER MORTALITY; CANCER REGRESSION; CANCER RELAPSE; CHILD; CHILDHOOD LEUKEMIA; CLINICAL PROTOCOL; COHORT ANALYSIS; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; GRAFT VERSUS HOST REACTION; HUMAN; INFECTION; MAJOR CLINICAL STUDY; MALE; PATIENT CARE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCHOOL CHILD;

ADOLESCENT; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHILD; CHILD, PRESCHOOL; DISEASE PROGRESSION; EPIDEMIOLOGIC METHODS; FEMALE; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; INFANT; LEUKEMIA, MYELOID, ACUTE; MALE; OPPORTUNISTIC INFECTIONS; RECURRENCE; REMISSION INDUCTION; SCANDINAVIA;

EID: 79951554407     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08554.x     Document Type: Article

References (15)

1. Abrahamsson, J., Clausen, N., Gustafsson, G., Hovi, L., Jonmundsson, G., Zeller, B., Forestier, E., Heldrup, J. & Hasle, H. (2007) Improved outcome after relapse in children with acute myeloid leukaemia. British Journal of Haematology, 136, 229-236.
2. Aladjidi, N., Auvrignon, A., Leblanc, T., Perel, Y., Benard, A., Bordigoni, P., Gandemer, V., Thuret, I., Dalle, J.H., Piguet, C., Pautard, B., Baruchel, A. & Leverger, G. (2003) Outcome in children with relapsed acute myeloid leukemia after initial treatment with the French Leucemie Aique Myeloide Enfant (LAME) 89/91 protocol of the French Society of Pediatric Hematology and Immunology. Journal of Clinical Oncology, 21, 4377-4385.
3. Ascioglu, S., Rex, J.H., de, P.B., Bennett, J.E., Bille, J., Crokaert, F., Denning, D.W., Donnelly, J.P., Edwards, J.E., Erjavec, Z., Fiere, D., Lortholary, O., Maertens, J., Meis, J.F., Patterson, T.F., Ritter, J., Selleslag, D., Shah, P.M., Stevens, D.A. & Walsh, T.J. (2002) Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: an international consensus. Clinical Infectious Diseases, 34, 7-14.
4. Cheson, B.D., Cassileth, P.A., Head, D.R., Schiffer, C.A., Bennett, J.M., Bloomfield, C.D., Brunning, R., Gale, R.P., Grever, M.R., Keating, M.J., Sawitsky, A., Stass, S., Weinstein, H. & Woods, W.G. (1990) Report of the National Cancer Institute-sponsored workshop on definitions of diagnosis and response in acute myeloid leukemia. Journal of Clinical Oncology, 8, 813-819.
5. Creutzig, U., Zimmermann, M., Reinhardt, D., Dworzak, M., Stary, J. & Lehrnbecher, T. (2004) Early deaths and treatment-related mortality in children undergoing therapy for acute myeloid leukemia: analysis of the multicenter clinical trials AML-BFM 93 and AML-BFM 98. Journal of Clinical Oncology, 22, 4384-4393.
6. Kaspers, G.J. & Creutzig, U. (2005) Pediatric acute myeloid leukemia: international progress and future directions. Leukemia, 19, 2025-2029.
7. Lie, S.O., Abrahamsson, J., Clausen, N., Forestier, E., Hasle, H., Hovi, L., Jonmundsson, G., Mellander, L., Siimes, M.A., Yssing, M., Zeller, B. & Gustafsson, G. (2005) Long-term results in children with AML: NOPHO-AML Study Group - report of three consecutive trials. Leukemia, 19, 2090-2100.
8. Molgaard-Hansen, L., Möttönen, M., Glosli, H., Jónmundsson, G.K., Abrahamsson, J. & Hasle, H. (2010) Early and treatment-related deaths in childhood acute myeloid leukaemia in the Nordic countries: 1984-2003. British Journal of Haematology, 151, 447-459.
9. Riley, L.C., Hann, I.M., Wheatley, K. & Stevens, R.F. (1999) Treatment-related deaths during induction and first remission of acute myeloid leukaemia in children treated on the Tenth Medical Research Council acute myeloid leukaemia trial (MRC AML10). The MCR Childhood Leukaemia Working Party. British Journal of Haematology, 106, 436-444.
10. Rubnitz, J.E., Lensing, S., Zhou, Y., Sandlund, J.T., Razzouk, B.I., Ribeiro, R.C. & Pui, C.H. (2004) Death during induction therapy and first remission of acute leukemia in childhood: the St. Jude experience. Cancer, 101, 1677-1684.
11. Rubnitz, J.E., Razzouk, B.I., Lensing, S., Pounds, S., Pui, C.H. & Ribeiro, R.C. (2007) Prognostic factors and outcome of recurrence in childhood acute myeloid leukemia. Cancer, 109, 157-163.
12. Sander, A., Zimmermann, M., Dworzak, M., Fleischhack, G., von, N.C., Reinhardt, D., Kaspers, G.J. & Creutzig, U. (2010) Consequent and intensified relapse therapy improved survival in pediatric AML: results of relapse treatment in 379 patients of three consecutive AML-BFM trials. Leukemia, 24, 1422-1428.
13. Slats, A.M., Egeler, R.M., van der Does-van den Berg, A., Korbijn, C., Hahlen, K., Kamps, W.A., Veerman, A.J. & Zwaan, C.M. (2005) Causes of death - other than progressive leukemia - in childhood acute lymphoblastic (ALL) and myeloid leukemia (AML): the Dutch Childhood Oncology Group experience. Leukemia, 19, 537-544.
14. Tsukimoto, I., Tawa, A., Horibe, K., Tabuchi, K., Kigasawa, H., Tsuchida, M., Yabe, H., Nakayama, H., Kudo, K., Kobayashi, R., Hamamoto, K., Imaizumi, M., Morimoto, A., Tsuchiya, S. & Hanada, R. (2009) Risk-stratified therapy and the intensive use of cytarabine improves the outcome in childhood acute myeloid leukemia: the AML99 trial from the Japanese Childhood AML Cooperative Study Group. Journal of Clinical Oncology, 27, 4007-4013.
15. Webb, D.K., Wheatley, K., Harrison, G., Stevens, R.F. & Hann, I.M. (1999) Outcome for children with relapsed acute myeloid leukaemia following initial therapy in the Medical Research Council (MRC) AML 10 trial. MRC Childhood Leukaemia Working Party. Leukemia, 13, 25-31.