The role of the doctor and the medical system in the diagnostic delay in pediatric malignancies

Cancer Epidemiology

Volumn 35, Issue 1, 2011, Pages 83-89

  Haimi, Motti ^a   Perez Nahum, Monique ^b   Stein, Nili ^c   Ben Arush, Myriam Weyl ^b,d  

^a CLALIT HEALTH SERVICES   (Israel)

^b RAMBAM MEDICAL CENTER   (Israel)

^c CARMEL MEDICAL CENTER   (Israel)

^d TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

Doctor's delay; Lag time; Parent's delay; Pediatric malignancies

Indexed keywords

ADOLESCENT; ARTICLE; CANCER DIAGNOSIS; CHILD; CHILDHOOD CANCER; CONSULTATION; DELAYED DIAGNOSIS; FEMALE; HEALTH CARE QUALITY; HEALTH CARE SYSTEM; HEALTH SURVEY; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PARENT; PHYSICIAN; PRIMARY HEALTH CARE; PRIORITY JOURNAL; PROGNOSIS; QUESTIONNAIRE; RETROSPECTIVE STUDY; SOLID TUMOR;

CHILD; CHILD, PRESCHOOL; DELIVERY OF HEALTH CARE; FEMALE; HUMANS; INFANT; MALE; NEOPLASMS; PHYSICIAN'S ROLE; REFERRAL AND CONSULTATION; RETROSPECTIVE STUDIES; RISK FACTORS; TIME FACTORS;

EID: 79951554231     PISSN: 18777821     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canep.2010.07.009     Document Type: Article

References (43)

1. The Israeli Center of Cancer Registration, Israel Ministry of Health.
2. Pratt C.B., Smith J.W., Woerner S. Factors leading to delay in the diagnosis and affecting survival of children with head and neck rhabdomyosarcoma. Pediatrics 1978, 61:30-34.
3. Flores L.E., Williams D.L., Bell B.A., O'Brien M., Ragab A.H. Delay in the diagnosis of pediatric brain tumors. Am J Dis Child 1986, 140:684-686.
4. Saha V., Love S., Eden T., Micallef-Eynaud P., Mackinlay G. Determinants of symptom interval in childhood cancer. Arch Dis Child 1993, 68:771-774.
5. Pollock B.H., Krischer J.P., Vietti T.J. Interval between symptom onset and diagnosis of pediatric solid tumors. J Pediatr 1991, 119:725-732.
6. Bleyer W.A. The impact of childhood cancer on the United States and the world. CA Cancer J Clin 1990, 40:355-367.
7. Greenwald H.P., Becker S.W., Nevitt M.C. Delay and noncompliance in cancer detection: a behavioral perspective for health planners. Milbank Med Fund Q Health Soc 1978, 56:212-230.
8. Thulesius H., Pola J., Hakansson A. Diagnosis delay in pediatric malignancies. A population based study. Acta Oncol 2000, 39:873-876.
9. Bleyer W.A., The U.S. Pediatric cancer clinical trials programmes: international implications and the way forward. Eur J Cancer 1997, 33:1439-1447.
10. Howard S.C., Wilimas J.A. Delays in diagnosis and treatment of childhood cancer: where in the world are they important?. Pediatr Blood Cancer 2005, 44:1-2.
11. Spurgeon P., Barwell F., Kerr D. Waiting times for cancer patients in England after general practitioners' referrals: retrospective national survey. BMJ 2000, 320(7238):838-839.
12. Wilkinson G.G., Edgerton F., Wallace H.J., Reese P., Patterson J., Priore R. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Search&itool=pubmed_AbstractPlus&term = Delay, stage of disease and survival from breast cancer. J Chronic Dis 1979, 32:365-373.
13. Neale A.V., Tilley B.C., Vernon S.W. Marital status, delay in seeking treatment and survival from breast cancer. Soc Sci Med 1986, 23:305-312.
14. Katz S.J., Hislop G., Thomas D.B., Larson E.B. Delay from symptom to diagnosis and treatment of breast cancer in Washington State and British Columbia. Med Care 1993, 31:264-268.
15. Ramirez A.J., Westcombe A.M., Burgess C.C., Sutton S., Littlejohn P., Richards M.A. Factors predicting delayed presentation of symptomatic breast cancer: a systematic review. Lancet 1999, 353:1127-1131.
16. Amir Z., Kwan S.Y., Landes D., Feber T., Williams S.A. Diagnostic delays in head and neck cancers. Eur J Cancer Care 1999, 8:198-203.
17. Allgar V.L., Neal R.D. Delays in the diagnosis of six cancers: analysis of data from the National Survey of NHS Patients: Cancer. Br J Cancer 2005, 92(11):1959-1970.
18. Salomaa E.R., Sallinen S., Hiekkanen H., Liippo K. Delays in the diagnosis and treatment of lung cancer. Chest 2005, 128(4):2282-2288.
19. Koyi H., Hillerdal G., Branden E. Patient's and doctors' delays in the diagnosis of chest tumors. Lung Cancer 2002, 35(1):53-57.
20. Wallace D.M., Bryan R.T., Dunn J.A., Begum G., Bathers S., West Midlands Urological Research Group Delay and survival in bladder cancer. BJU Int 2002, 89(9):868-878.
21. Sainsbury R., Johnston C., Haward B. Effect on survival of delays in referral of patients with breast-cancer symptoms: a retrospective analysis. Lancet 1999, 353(9159):1132-1135.
22. Brouns F., Stas M., De Wever I. Delay in diagnosis of soft tissue sarcomas. Eur J Surg Oncol 2003, 29:440-445.
23. Widhe B., Widhe T. Initial symptoms and clinical features in osteosarcoma and Ewing sarcoma. J Bone Joint Surg Am 2000, 82(5):667-674.
24. Wurtz L.D., Peabody T.D., Simon M.A. Delay in the diagnosis and treatment of primary bone sarcoma of the pelvis. J Bone Joint Surg Am 1999, 81(3):317-325.
25. Arksey H., Sloper P. Disputed diagnoses: the case of RSI and childhood cancer. Soc Sci Med 1999, 49:483-497.
26. Eiser C., Parkyn T., Havermans T., McNinch A. Parents' recall on the diagnosis of cancer in their child. Psychooncology 1994, 3:197-203.
27. Hamre M.R., Williams J., Chuba P., Bhambhani K., Ravindranath Y., Severson R.K. Early deaths in childhood cancer. Med Pediatr Oncol 2000, 34:343-347.
28. Aynsely-Green A., Barker M., Burr S., Macfarlane A., Morgan J., Sibert J. BMJ. Who is speaking for children and adolescents and for their health at the policy level? 2000, 321:229-232.
29. Dixon-Woods M., Findlay M., Young B., Cox H., Heney D. Parents' accounts of obtaining a diagnosis of childhood cancer. Lancet 2001, 357:670-674.
30. Klein-Geltink J.E., Pogany L.M., Barr R.D., Greenberg M.L., Mery L.S. Waiting times for cancer care in Canadian children: impact of distance, clinical, and demographic factors. Pediatr Blood Cancer 2004, 43:1-10.
31. Mehta V., Chapman A., McNeely P.D., Walling S., Howes W.J. Latency between symptom onset and diagnosis of pediatric brain tumors: an Eastern Canadian geographic study. Neurosurgery 2002, 51(2):372-373. discussion 365-72.
32. Fajardo-Gutierrez A., Sandoval-Mex A.M., Mejia-Arangure J.M. Clinical and social factors that affect the time to diagnosis of Mexican children with cancer. Med Pediatr Oncol 2002, 39:25-31.
33. Wessels G., Hesseling P.B. Outcome of children treated for cancer in the Republic of Namibia. Med Pediatr Oncol 1996, 27:160-164.
34. Brown R.A., Rode H., Millar A.J., Sinclair-Smith C., Cywes S. Colorectal carcinoma in children. J Pediatr Surg 1992, 27:919-921.
35. Edgeworth J., Bullock P., Bailey A., Gallagher A., Crouchman M. Why are brain tumors still being missed?. Arch Dis Child 1996, 74:148-151.
36. Bonilla M., Moreno N., Marina N., deReyes G., Shurtleff S.A., Downing J.R. Acute lymphoblastic leukemia in a developing country: preliminary results of a nonrandomized clinical trial in El Salvador. J Pediatr Hematol Oncol 2000, 22:495-501.
37. Metzger M.L., Howard S.C., Fu L.C., Pena A., Stefan R., Hancock M.L. Outcome of childhood acute lymphoblastic leukaemia in resource-poor countries. Lancet 2003, 362:706-708.
38. Haimi M., Peretz N.M., Ben Arush M.W. Delay in diagnosis of children with cancer: a retrospective study of 315 children. Pediatr Hematol Oncol 2004, 21:37-48.
39. McGraw K.O., Gordy S., Wong S.S. How many subjects to screen? A practical procedure for examining multivariate normal probabilities for correlated variables. J Consult Clin Psychol 1984, 62:960-964.
40. Winer B.J., Brown D.R., Michels K.M. Statistical principles in experimental design 1991, McGraw-Hill, New York.
41. Howard S.C., Pedrosa M., Lins M., Pedrosa A., Pui C.H., Ribeiro R.C. Establishment of a pediatric oncology program and outcomes of childhood acute lymphoblastic leukemia in a resource-poor area. JAMA 2004, 291:2471-2475.
42. Zajaczek S., Jakubowska A., Kurzawski G., Krzystolik Z., Lubinski J. Age at diagnosis to discriminate those patients for whom constitutional DNA sequencing is appropriate in sporadic unilateral retinoblastoma. Eur J Cancer 1998, 34:1919-1921.
43. Polnay L. Child health surveillance. BMJ 1989, 299:1351-1352.