Macrophyllionium and macrophyllines A and B, oxindole alkaloids from uncaria macrophylla

Journal of Natural Products

Volumn 74, Issue 1, 2011, Pages 12-15

  Wang, Kou ^a,b   Zhou, Xiao Yu ^c   Wang, Yuan Yuan ^a   Li, Ming Ming ^a,b   Li, Yin Shan ^d   Peng, Li Yan ^a   Cheng, Xiao ^a   Lie, Yan ^a   Wang, Yi Ping ^c   Zhao, Qin Shi ^a  

^a KUNMING INSTITUTE OF BOTANY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

^d DALI UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID DERIVATIVE; CORYNANTHEIDINE; CORYNOXINE; DIHYDROCORYNANTHEINE; ISORHYNCHOPHYLLINE; MACROPHYLLINE A; MACROPHYLLINE B; MACROPHYLLIONIUM; OXINDOLE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA CONSTRICTION; ARTICLE; CELL STRAIN HL 60; CONCENTRATION RESPONSE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; MALE; MEDICINAL PLANT; NONHUMAN; RAT; THORACIC AORTA; UNCARIA; UNCARIA MACROPHYLLA; VASODILATATION;

ALKALOIDS; ANIMALS; AORTA, THORACIC; DRUG SCREENING ASSAYS, ANTITUMOR; DRUGS, CHINESE HERBAL; HL-60 CELLS; HUMANS; INDOLE ALKALOIDS; INDOLES; INHIBITORY CONCENTRATION 50; MALE; MOLECULAR STRUCTURE; PHENYLEPHRINE; POTASSIUM CHLORIDE; RATS; RATS, SPRAGUE-DAWLEY; STEREOISOMERISM; UNCARIA; VASODILATION;

RATTUS; UNCARIA;

EID: 79951546686     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/np1004938     Document Type: Article

References (24)

1. Delectis Florae Reipublicae Popularis Sinicae Agendae Academiae Sinicae Edita. Florae Reipublicae Popularis Sinicae; Science Press: Beijing, 1999; Vol. 71 (1), pp 247-259.
2. The State Pharmacopoeia Committee of China. Pharmacopoeia of the People's Republic of China; Chemical Industry Press: Beijing, 2005; Vol. 1, p 180.
3. Zhang, F.; Sun, A. S.; Yu, L. M.; Wu, Q.; Gong, Q. H. J. Pharm. Pharmacol. 2008, 60, 1673-1678.
4. Zhang, W. B.; Chen, C. X.; Sim, S. M.; Kwan, C. Y. Naunyn. Schmiedebergs Arch. Pharmacol. 2004, 369, 232-238.
5. Kang, T. H.; Murakami, Y.; Takayama, H.; Kitajima, M.; Aimi, N.; Watanabe, H.; Matsumoto, K. Life Sci. 2004, 76, 331-343.
6. Sakakibara, I.; Terabayashi, S.; Kubo, M.; Higuchi, M.; Komatsu, Y.; Okada, M.; Taki, K.; Kamei, J. Phytomedicine 1999, 6, 163-168.
7. Phillipson, J. D.; Hemingway, S. R. Phytochemistry 1973, 12, 2795-2798.
8. Sakakibara, I.; Takahashi, H.; Terabayashi, S.; Yuzurihara, M.; Kubo, M.; Ishige, A.; Higuchi, M.; Komatsu, Y.; Okada, M.; Maruno, M.; Biqiang, C.; Jiang, H. X. Phytomedicine 1998, 5, 83-86.
9. Zheng, J. N.; Wang, D. Y. Guiding J. Tradit. Chin. Med. Pharm. 2009, 15, 80-82.
10. Wenkert, E.; Bindra, J. S.; Chang, C. J.; Cochran, D. W.; Schell, F. M. Acc. Chem. Res. 1974, 7, 46-51.
11. Lim, K. H.; Sim, K. M.; Tan, G. H.; Kam, T. S. Phytochemistry 2009, 70, 1182-1186.
12. Yuan, D.; Ma, B.; Wu, C. F.; Yang, J. Y.; Zhang, L. J.; Liu, S. K.; Wu, L. J.; Kano, Y. J. Nat. Prod. 2008, 71, 1271-1274.
13. Kam, T. S.; Choo, Y. M. J. Nat. Prod. 2004, 67, 547-552.
14. Feng, T.; Li, Y.; Cai, X. H.; Gong, X.; Liu, Y. P.; Zhang, R. T.; Zhang, X. Y.; Tan, Q. G.; Luo, X. D. J. Nat. Prod. 2009, 72, 1836-1841.
15. Kutchan, T. M. Phytochemistry 1993, 32, 493-506.
16. Rueffer, M.; Nagakura, N.; Zenk, M. H. Tetrahedron Lett. 1978, 19, 1593-1596.
17. Shamma, M.; Shine, R. J.; Kompis, I.; Sticzay, T.; Morsingh, F.; Poisson, J.; Pousset, J. L. J. Am. Chem. Soc. 1967, 89, 1739-1940.
18. Abou-Donia, A. H.; Abib, A.-A.; Seif El Din, A.; Evidente, A.; Gaber, M.; Scopa, A. Phytochemistry 1992, 31, 2139-2141.
19. Attaur-Rahman; Malik, S.; Hasan, S.; Choudhry, I. M.; Ni, C. Z.; Clardy, J. Tetrahedron Lett. 1995, 36, 1993-1996.
20. Aiello, A.; Fattorusso, E.; Luciano, P.; Menna, M.; Vitalone, R. J. Nat. Prod. 2010, 73, 620-622.
21. Paradowska, K.; Wolniak, M.; Pisklak, M.; Glinski, J. A.; Davey, M. H.; Wawer, I. Solid State Nucl. Magn. Reson. 2008, 34, 202-209.
22. Heitzman, M. E.; Neto, C. C.; Winiarz, E.; Vaisberg, A. J.; Hammond, G. B. Phytochemistry 2005, 66, 5-29.
23. Mosmann, T. J. Immunol. Methods 1983, 65, 55-63.
24. Reed, L. J.; Muench, H. Am. J. Hyg. 1938, 27, 493-497.