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Volumn 13, Issue 2, 2011, Pages 120-130

Tyr phosphatase-mediated P-ERK inhibition suppresses senescence in EIA + v-raf transformed cells, which, paradoxically, are apoptosis-protected in a MEK-dependent manner

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; E1A PROTEIN; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PROTEIN TYROSINE PHOSPHATASE; RAF PROTEIN;

EID: 79951486303     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1593/neo.101152     Document Type: Article
Times cited : (17)

References (46)
  • 1
    • 27544453376 scopus 로고    scopus 로고
    • Mutations of C-RAF arerare in human cancer because C-RAF has a low basal kinase activity compared with B-RAF
    • Emuss V, Garnett M, Mason C, and Marais R (2005). Mutations of C-RAF arerare in human cancer because C-RAF has a low basal kinase activity compared with B-RAF. Cancer Res 65, 9719-9726.
    • (2005) Cancer Res , vol.65 , pp. 9719-9726
    • Emuss, V.1    Garnett, M.2    Mason, C.3    Marais, R.4
  • 4
    • 0032541671 scopus 로고    scopus 로고
    • Cell cycle targets of Ras/Raf signalling
    • Kerkhoff E and Rapp UR (1998). Cell cycle targets of Ras/Raf signalling. Oncogene 17, 1457-1462.
    • (1998) Oncogene , vol.17 , pp. 1457-1462
    • Kerkhoff, E.1    Rapp, U.R.2
  • 7
    • 12944305960 scopus 로고    scopus 로고
    • Raf induces NF-κB by membrane shuttle kinase MEKK1, a signalingpathway critical for transformation
    • Baumann B, Weber CK, Troppmair J, Whiteside S, Israel A, and Rapp UR (2000). Raf induces NF-κB by membrane shuttle kinase MEKK1, a signalingpathway critical for transformation. Proc Natl Acad Sci USA 97, 4615-4620.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 4615-4620
    • Baumann, B.1    Weber, C.K.2    Troppmair, J.3    Whiteside, S.4    Israel, A.5    Rapp, U.R.6
  • 8
    • 0345498292 scopus 로고    scopus 로고
    • Bcl-2 targets the protein kinase Raf-1to mitochondria
    • Wang HG, Rapp UR, and Reed JC (1996a). Bcl-2 targets the protein kinase Raf-1to mitochondria. Cell 87, 629-638.
    • (1996) Cell , vol.87 , pp. 629-638
    • Wang, H.G.1    Rapp, U.R.2    Reed, J.C.3
  • 9
    • 0029937303 scopus 로고    scopus 로고
    • Bcl-2 interactingprotein, BAG-1, binds to and activates the kinase Raf-1
    • Wang HG, Takayama S, Rapp UR, and Reed JC (1996b). Bcl-2 interactingprotein, BAG-1, binds to and activates the kinase Raf-1. Proc Natl Acad Sci USA 93, 7063-7068.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 7063-7068
    • Wang, H.G.1    Takayama, S.2    Rapp, U.R.3    Reed, J.C.4
  • 10
    • 0034944380 scopus 로고    scopus 로고
    • Raf-1 promotes cell survivalby antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERKindependent mechanism
    • Chen J, Fujii K, Zhang L, Roberts T, and Fu H (2001). Raf-1 promotes cell survivalby antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERKindependent mechanism. Proc Natl Acad Sci USA 98, 7783-7788.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7783-7788
    • Chen, J.1    Fujii, K.2    Zhang, L.3    Roberts, T.4    Fu, H.5
  • 11
    • 11144267126 scopus 로고    scopus 로고
    • Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1
    • O'Neill E, Rushworth L, Baccarini M, and Kolch W (2004). Role of the kinase MST2 in suppression of apoptosis by the proto-oncogene product Raf-1. Science 306, 2267-2270.
    • (2004) Science , vol.306 , pp. 2267-2270
    • O'Neill, E.1    Rushworth, L.2    Baccarini, M.3    Kolch, W.4
  • 13
    • 0027364980 scopus 로고
    • Critical tyrosine residues regulatethe enzymatic and biological activity of Raf-1 kinase
    • Fabian JR, Daar IO, and Morrison DK (1993). Critical tyrosine residues regulatethe enzymatic and biological activity of Raf-1 kinase. Mol Cell Biol 13, 7170-7179.
    • (1993) Mol Cell Biol , vol.13 , pp. 7170-7179
    • Fabian, J.R.1    Daar, I.O.2    Morrison, D.K.3
  • 14
    • 0030881165 scopus 로고    scopus 로고
    • Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1
    • Bosch E, Cherwinski H, Peterson D, and McMahon M (1997). Mutations of critical amino acids affect the biological and biochemical properties of oncogenic A-Raf and Raf-1. Oncogene 15, 1021-1033.
    • (1997) Oncogene , vol.15 , pp. 1021-1033
    • Bosch, E.1    Cherwinski, H.2    Peterson, D.3    McMahon, M.4
  • 15
    • 0032563961 scopus 로고    scopus 로고
    • Oncogenes, growthfactors and phorbol esters regulate Raf-1 through common mechanisms
    • Barnard D, Diaz B, Clawson D, and Marshall M (1998). Oncogenes, growthfactors and phorbol esters regulate Raf-1 through common mechanisms. Oncogene 17, 1539-1547.
    • (1998) Oncogene , vol.17 , pp. 1539-1547
    • Barnard, D.1    Diaz, B.2    Clawson, D.3    Marshall, M.4
  • 16
    • 52049084154 scopus 로고    scopus 로고
    • Oncogenic B-Raf V600E inhibitsapoptosis and promotes ERK-dependent inactivation of Bad and Bim
    • Sheridan C, Brumatti G, and Martin SJ (2008). Oncogenic B-Raf V600E inhibitsapoptosis and promotes ERK-dependent inactivation of Bad and Bim. J Biol Chem 283, 22128-22135.
    • (2008) J Biol Chem , vol.283 , pp. 22128-22135
    • Sheridan, C.1    Brumatti, G.2    Martin, S.J.3
  • 17
    • 0030944985 scopus 로고    scopus 로고
    • Oncogenicras provokes premature cell senescence associated with accumulation of p53 and p16INK4a
    • Serrano M, Lin AW, McCurrach ME, Beach D, and Lowe SW (1997). Oncogenicras provokes premature cell senescence associated with accumulation of p53 and p16INK4a. Cell 88, 593-602.
    • (1997) Cell , vol.88 , pp. 593-602
    • Serrano, M.1    Lin, A.W.2    McCurrach, M.E.3    Beach, D.4    Lowe, S.W.5
  • 18
    • 0032192153 scopus 로고    scopus 로고
    • Senescence of humanfibroblasts induced by oncogenic Raf
    • Zhu J, Woods D, McMahon M, and Bishop JM (1998). Senescence of humanfibroblasts induced by oncogenic Raf. Genes Dev 12, 2997-3007.
    • (1998) Genes Dev , vol.12 , pp. 2997-3007
    • Zhu, J.1    Woods, D.2    McMahon, M.3    Bishop, J.M.4
  • 19
    • 0032190629 scopus 로고    scopus 로고
    • Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
    • Lin AW, Barradas M, Stone JC, van Aelst L, Serrano M, and Lowe SW (1998). Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling. Genes Dev 12, 3008-3019.
    • (1998) Genes Dev , vol.12 , pp. 3008-3019
    • Lin, A.W.1    Barradas, M.2    Stone, J.C.3    van Aelst, L.4    Serrano, M.5    Lowe, S.W.6
  • 24
    • 27644436010 scopus 로고    scopus 로고
    • Mixed-disulfide folding intermediates between thyroglobulin and endoplasmicreticulum resident oxidoreductases ERp57 and protein disulfide isomerase
    • Di Jeso B, Park YN, Ulianich L, Treglia AS, Urbanas ML, High S, and Arvan P (2005). Mixed-disulfide folding intermediates between thyroglobulin and endoplasmicreticulum resident oxidoreductases ERp57 and protein disulfide isomerase. Mol Cell Biol 25, 9793-9805.
    • (2005) Mol Cell Biol , vol.25 , pp. 9793-9805
    • Di Jeso, B.1    Park, Y.N.2    Ulianich, L.3    Treglia, A.S.4    Urbanas, M.L.5    High, S.6    Arvan, P.7
  • 26
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytoxity assay
    • Mosmann T (1993). Rapid colorimetric assay for cellular growth and survival:application to proliferation and cytoxity assay. J Immunol Methods 65, 55-63.
    • (1993) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 27
    • 0027473687 scopus 로고
    • Theadenovirus E1A gene blocks the differentiation of a thyroid epithelial cell line, however the neoplastic phenotype is achieved only after cooperation with otheroncogenes
    • Berlingieri MT, Santoro M, Battaglia C, Grieco M, and Fusco A (1993). Theadenovirus E1A gene blocks the differentiation of a thyroid epithelial cell line, however the neoplastic phenotype is achieved only after cooperation with otheroncogenes. Oncogene 8, 249-255.
    • (1993) Oncogene , vol.8 , pp. 249-255
    • Berlingieri, M.T.1    Santoro, M.2    Battaglia, C.3    Grieco, M.4    Fusco, A.5
  • 29
    • 21644487114 scopus 로고    scopus 로고
    • p21-activated kinase 1 (Pak1)-dependentphosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylationof BAD, and Bcl-2 association
    • Jin S, Zhuo Y, Guo W, and Field J (2005). p21-activated kinase 1 (Pak1)-dependentphosphorylation of Raf-1 regulates its mitochondrial localization, phosphorylationof BAD, and Bcl-2 association. J Biol Chem 280, 24698-24705.
    • (2005) J Biol Chem , vol.280 , pp. 24698-24705
    • Jin, S.1    Zhuo, Y.2    Guo, W.3    Field, J.4
  • 30
    • 38949086516 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases: Regulatory mechanisms
    • den Hertog J, Ostman A, and Böhmer FD (2008). Protein tyrosine phosphatases:regulatory mechanisms. FEBS J 275, 831-847.
    • (2008) FEBS J , vol.275 , pp. 831-847
    • den Hertog, J.1    Ostman, A.2    Böhmer, F.D.3
  • 31
    • 0035902115 scopus 로고    scopus 로고
    • Proliferation, cell cycle and apoptosis in cancer
    • Evan GI and Vousden KH (2001). Proliferation, cell cycle and apoptosis in cancer. Nature 411, 342-348.
    • (2001) Nature , vol.411 , pp. 342-348
    • Evan, G.I.1    Vousden, K.H.2
  • 32
    • 0035984912 scopus 로고    scopus 로고
    • ROS, stress-activated kinases and stress signaling in cancer
    • Benhar M, Engelberg D, and Levitzki A (2002). ROS, stress-activated kinases and stress signaling in cancer. EMBO Rep 3, 420-425.
    • (2002) EMBO Rep , vol.3 , pp. 420-425
    • Benhar, M.1    Engelberg, D.2    Levitzki, A.3
  • 33
    • 34047245311 scopus 로고    scopus 로고
    • Chemoresistance of endothelialcells induced by basic fibroblast growth factor depends on Raf-1-mediatedinhibition of the proapoptotic kinase, ASK1
    • Alavi AS, Acevedo L, Min W, and Cheresh DA (2007). Chemoresistance of endothelialcells induced by basic fibroblast growth factor depends on Raf-1-mediatedinhibition of the proapoptotic kinase, ASK1. Cancer Res 67, 2766-2772.
    • (2007) Cancer Res , vol.67 , pp. 2766-2772
    • Alavi, A.S.1    Acevedo, L.2    Min, W.3    Cheresh, D.A.4
  • 35
    • 43049101029 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) and cancer
    • Keyse SM (2008). Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 27, 253-261.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 253-261
    • Keyse, S.M.1
  • 36
    • 0033800083 scopus 로고    scopus 로고
    • Extracellular signals and scores of phosphatases: All roads lead to MAP kinase
    • Saxena M and Mustelin T (2000). Extracellular signals and scores of phosphatases:all roads lead to MAP kinase. Semin Immunol 12, 387-396.
    • (2000) Semin Immunol , vol.12 , pp. 387-396
    • Saxena, M.1    Mustelin, T.2
  • 38
    • 33750299450 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases: Fromgenes, to function, to disease
    • Tonks NK (2006). Protein tyrosine phosphatases: fromgenes, to function, to disease. Nat Rev Mol Cell Biol 7, 833-846.
    • (2006) Nat Rev Mol Cell Biol , vol.7 , pp. 833-846
    • Tonks, N.K.1
  • 39
  • 41
    • 12344257683 scopus 로고    scopus 로고
    • DNA tumor viruses-the spies who lyse us
    • O'Shea CC (2005). DNA tumor viruses-the spies who lyse us. Curr Opin Genet Dev 15, 18-26.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 18-26
    • O'Shea, C.C.1
  • 42
    • 34147133693 scopus 로고    scopus 로고
    • Activation of ERK1/2 occurs independentlyof KRAS or BRAF status in endometrial cancer and is associated with favorableprognosis
    • Mizumoto Y, Kyo S, Mori N, Sakaguchi J, Ohno S, Maida Y, Hashimoto M, Takakura M, and Inoue M (2007). Activation of ERK1/2 occurs independentlyof KRAS or BRAF status in endometrial cancer and is associated with favorableprognosis. Cancer Sci 98, 652-658.
    • (2007) Cancer Sci , vol.98 , pp. 652-658
    • Mizumoto, Y.1    Kyo, S.2    Mori, N.3    Sakaguchi, J.4    Ohno, S.5    Maida, Y.6    Hashimoto, M.7    Takakura, M.8    Inoue, M.9
  • 44
    • 33845588905 scopus 로고    scopus 로고
    • Lack of association between BRAF V600E mutation and mitogen-activated protein kinase activation in papillary thyroid carcinoma
    • Zuo H, Nakamura Y, Yasuoka H, Zhang P, Nakamura M, Mori I, Miyauchi A, and Kakudo K (2007). Lack of association between BRAF V600E mutation and mitogen-activated protein kinase activation in papillary thyroid carcinoma. Pathol Int 57, 12-20.
    • (2007) Pathol Int , vol.57 , pp. 12-20
    • Zuo, H.1    Nakamura, Y.2    Yasuoka, H.3    Zhang, P.4    Nakamura, M.5    Mori, I.6    Miyauchi, A.7    Kakudo, K.8
  • 45
    • 53949121599 scopus 로고    scopus 로고
    • Lack of cytoplasmic ERK activation is an independent adverse prognostic factor inprimary cutaneous melanoma
    • Jovanovic B, Kröckel D, Linden D, Nilsson B, Egyhazi S, and Hansson J (2008). Lack of cytoplasmic ERK activation is an independent adverse prognostic factor inprimary cutaneous melanoma. J Invest Dermatol 128, 2696-2704.
    • (2008) J Invest Dermatol , vol.128 , pp. 2696-2704
    • Jovanovic, B.1    Kröckel, D.2    Linden, D.3    Nilsson, B.4    Egyhazi, S.5    Hansson, J.6
  • 46
    • 58649090898 scopus 로고    scopus 로고
    • Phosphorylationof ERK1/2 and prognosis of clear cell renal cell carcinoma
    • Lee HJ, Kim DI, Kang GH, Kwak C, Ku JH, and Moon KC (2009). Phosphorylationof ERK1/2 and prognosis of clear cell renal cell carcinoma. Urology 73, 394-399.
    • (2009) Urology , vol.73 , pp. 394-399
    • Lee, H.J.1    Kim, D.I.2    Kang, G.H.3    Kwak, C.4    Ku, J.H.5    Moon, K.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.