P300 amplitude is insensitive to working memory load in schizophrenia

BMC Psychiatry

Volumn 11, Issue , 2011, Pages

  Gaspar, Pablo A ^a,b   Ruiz, Sergio ^c,d,e   Zamorano, Francisco ^e   Altayó, Marcela ^e   Pérez, Carolina ^e   Bosman, Conrado A ^f   Aboitiz, Francisco ^e  

^a UNIVERSIDAD DE CHILE   (Chile)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY OF TÜBINGEN   (Germany)

^e PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^f RADBOUD UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AMPLITUDE MODULATION; ARTICLE; ATTENTION; CLINICAL ARTICLE; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; EVENT RELATED POTENTIAL; FEMALE; HUMAN; LATENT PERIOD; MALE; MEMORY CONSOLIDATION; MENTAL PATIENT; P300 AMPLITUDE; PARANOID SCHIZOPHRENIA; TASK PERFORMANCE; WORKING MEMORY; ANALYSIS OF VARIANCE; BRAIN CORTEX; ELECTROENCEPHALOGRAPHY; HOSPITALIZATION; NEUROPSYCHOLOGICAL TEST; PATHOPHYSIOLOGY; PHYSIOLOGY; SCHIZOPHRENIA; SHORT TERM MEMORY;

ADULT; ANALYSIS OF VARIANCE; CEREBRAL CORTEX; ELECTROENCEPHALOGRAPHY; EVENT-RELATED POTENTIALS, P300; FEMALE; HUMANS; MALE; MEMORY, SHORT-TERM; NEUROPSYCHOLOGICAL TESTS; SCHIZOPHRENIA; SEVERITY OF ILLNESS INDEX;

EID: 79851511476     PISSN: None     EISSN: 1471244X     Source Type: Journal    
DOI: 10.1186/1471-244X-11-29     Document Type: Article

References (27)

1. Fuster JM. Unit activity in prefrontal cortex during delayed-response performance: neuronal correlates of transient memory. J Neurophysiol 1973, 36:61-78.
2. Vogel EK, McCollough AW, Machizawa MG. Neural measures reveal individual differences in controlling access to working memory. Nature 2005, 438:500-503. 10.1038/nature04171, 16306992.
3. Schmiedt C, Brand A, Hildebrandt H, Basar-Eroglu C. Event-related theta oscillations during working memory tasks in patients with schizophrenia and healthy controls. Brain Res Cogn Brain Res 2005, 25:936-947. 10.1016/j.cogbrainres.2005.09.015, 16289526.
4. Kok A. On the utility of P3 amplitude as a measure of processing capacity. Psychophysiology 2001, 38:557-577. 10.1017/S0048577201990559, 11352145.
5. Linden DE. The p300: where in the brain is it produced and what does it tell us?. Neuroscientist 2005, 11:563-576. 10.1177/1073858405280524, 16282597.
6. Gevins A, Cutillo B. Spatiotemporal dynamics of component processes in human working memory. Electroencephalogr Clin Neurophysiol 1993, 87:128-143. 10.1016/0013-4694(93)90119-G, 7691540.
7. Green MF. What are the functional consequences of neurocognitive deficits in schizophrenia?. Am J Psychiatry 1996, 153:321-330.
8. Goldman-Rakic PS. Working memory dysfunction in schizophrenia. J Neuropsychiatry Clin Neurosci 1994, 6:348-357.
9. Conklin HM, Curtis CE, Calkins ME, Iacono WG. Working memory functioning in schizophrenia patients and their first-degree relatives: cognitive functioning shedding light on etiology. Neuropsychologia 2005, 43:930-942. 10.1016/j.neuropsychologia.2004.09.013, 15716163.
10. Heaton RK, Gladsjo JA, Palmer BW, Kuck J, Marcotte TD, Jeste DV. Stability and course of neuropsychological deficits in schizophrenia. Arch Gen Psychiatry 2001, 58:24-32. 10.1001/archpsyc.58.1.24, 11146755.
11. Bramon E, McDonald C, Croft RJ, Landau S, Filbey F, Gruzelier JH, Sham PC, Frangou S, Murray RM. Is the P300 wave an endophenotype for schizophrenia? A meta-analysis and a family study. Neuroimage 2005, 27:960-968. 10.1016/j.neuroimage.2005.05.022, 16009570.
12. Jeon YW, Polich J. Meta-analysis of P300 and schizophrenia: patients, paradigms, and practical implications. Psychophysiology 2003, 40:684-701. 10.1111/1469-8986.00070, 14696723.
13. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987, 13:261-276.
14. Gevins A, Smith ME. Neurophysiological measures of working memory and individual differences in cognitive ability and cognitive style. Cereb Cortex 2000, 10:829-839. 10.1093/cercor/10.9.829, 10982744.
15. McEvoy LK, Smith ME, Gevins A. Dynamic cortical networks of verbal and spatial working memory: effects of memory load and task practice. Cereb Cortex 1998, 8:563-574. 10.1093/cercor/8.7.563, 9823478.
16. Hillyard SA, Kutas M. Electrophysiology of cognitive processing. Annu Rev Psychol 1983, 34:33-61. 10.1146/annurev.ps.34.020183.000341, 6338812.
17. Maris E, Schoffelen JM, Fries P. Nonparametric statistical testing of coherence differences. J Neurosci Methods 2007, 163:161-175. 10.1016/j.jneumeth.2007.02.011, 17395267.
18. Oken BS, Chiappa KH. Statistical issues concerning computerized analysis of brainwave topography. Ann Neurol 1986, 19:493-497. 10.1002/ana.410190511, 3487282.
19. Krieger S, Lis S, Janik H, Cetin T, Gallhofer B, Meyer-Lindenberg A. Executive function and cognitive subprocesses in first-episode, drug-naive schizophrenia: an analysis of N-back performance. Am J Psychiatry 2005, 162:1206-1208. 10.1176/appi.ajp.162.6.1206, 15930072.
20. Winterer G, Coppola R, Egan MF, Goldberg TE, Weinberger DR. Functional and effective frontotemporal connectivity and genetic risk for schizophrenia. Biol Psychiatry 2003, 54:1181-1192. 10.1016/S0006-3223(03)00532-8, 14643085.
21. Perlstein WM, Dixit NK, Carter CS, Noll DC, Cohen JD. Prefrontal cortex dysfunction mediates deficits in working memory and prepotent responding in schizophrenia. Biol Psychiatry 2003, 53:25-38. 10.1016/S0006-3223(02)01675-X, 12513942.
22. Tan HY, Choo WC, Fones CS, Chee MW. fMRI study of maintenance and manipulation processes within working memory in first-episode schizophrenia. Am J Psychiatry 2005, 162:1849-1858. 10.1176/appi.ajp.162.10.1849, 16199831.
23. Molina V, Sanz J, Munoz F, Casado P, Hinojosa JA, Sarramea F, Martin-Loeches M. Dorsolateral prefrontal cortex contribution to abnormalities of the P300 component of the event-related potential in schizophrenia. Psychiatry Res 2005, 140:17-26. 10.1016/j.pscychresns.2004.04.006, 16213126.
24. van den Heuvel MP, Mandl RC, Stam CJ, Kahn RS, Hulshoff Pol HE. Aberrant frontal and temporal complex network structure in schizophrenia: a graph theoretical analysis. J Neurosci 2010, 30:15915-15926. 10.1523/JNEUROSCI.2874-10.2010, 21106830.
25. Polich J. Updating P300: an integrative theory of P3a and P3b. Clin Neurophysiol 2007, 118:2128-2148. 10.1016/j.clinph.2007.04.019, 2715154, 17573239.
26. Mathalon DH, Ford JM, Rosenbloom M, Pfefferbaum A. P300 reduction and prolongation with illness duration in schizophrenia. Biol Psychiatry 2000, 47:413-427. 10.1016/S0006-3223(99)00151-1, 10704953.
27. Karoumi B, Laurent A, Rosenfeld F, Rochet T, Brunon AM, Dalery J, d'Amato T, Saoud M. Alteration of event related potentials in siblings discordant for schizophrenia. Schizophr Res 2000, 41:325-334. 10.1016/S0920-9964(99)00062-6, 10708341.