AMINOTRANSFERASE BLOOD LEVEL;
ANAPHYLAXIS;
ANGIONEUROTIC EDEMA;
BODY WEIGHT;
CARDIOVASCULAR DISEASE;
CARDIOVASCULAR RISK;
CONSTIPATION;
DEPRESSION;
DRUG EFFICACY;
DRUG HYPERSENSITIVITY;
DRUG MEGADOSE;
DRUG SAFETY;
EDEMA;
ERYTHEMA;
EUROPEAN UNION;
FATIGUE;
FLU LIKE SYNDROME;
FRACTURE;
GASTROINTESTINAL DISEASE;
GLYCEMIC CONTROL;
HEADACHE;
HUMAN;
HYPOGLYCEMIA;
LYMPHOCYTOPENIA;
MUSCULOSKELETAL DISEASE;
MYALGIA;
NAUSEA;
NON INSULIN DEPENDENT DIABETES MELLITUS;
NONHUMAN;
PANCREATITIS;
PERIPHERAL EDEMA;
POSTMARKETING SURVEILLANCE;
RANDOMIZED CONTROLLED TRIAL;
RESPIRATORY TRACT INFECTION;
REVIEW;
RISK BENEFIT ANALYSIS;
RISK MANAGEMENT;
SIDE EFFECT;
SINUSITIS;
SKIN MANIFESTATION;
STEVENS JOHNSON SYNDROME;
TREATMENT RESPONSE;
ARTICLE;
COMPARATIVE STUDY;
DRUG APPROVAL;
DRUG INTERACTION;
ADAMANTANE;
DIABETES MELLITUS, TYPE 2;
DIPEPTIDES;
DIPEPTIDYL-PEPTIDASE IV INHIBITORS;
DRUG APPROVAL;
DRUG INTERACTIONS;
EUROPEAN UNION;
HUMANS;
HYPOGLYCEMIC AGENTS;
U.S. Food and Drug Administration - Center for Drug Evaluation and Research 23 January
U.S. Food and Drug Administration - Center for Drug Evaluation and Research "Application number: NDA 22-350. Statistical review" 23 January 2009: 73 pages.
European Medicines Agency - CHMP posted on the EMA website on 27 December
European Medicines Agency - CHMP "Assessment report for Onglyza Scientific discussion n° EMEA/H/C/001039": 57 pages; posted on the EMA website on 27 December 2009.
Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes
DOI 10.1111/j.1463-1326.2008.00876.x
8- Rosenstock J et al. "Glucose-lowering activity of the dipeptidyl peptidase-4 inhibitor saxagliptin in drug-naive patients with type 2 diabetes" Diabetes Obes Metab 2008; 10 (5): 376-386. (Pubitemid 351524285)
Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: A randomised controlled trial
Chacra AR et al. "Saxagliptin added to a submaximal dose of sulphonylurea improves glycaemic control compared with uptitration of sulphonylurea in patients with type 2 diabetes: a randomised controlled trial" Int J Clin Pract 2009; 63 (9): 1395-1406.
Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: A randomized controlled trial
Jadzinsky M et al. "Saxagliptin given in combination with metformin as initial therapy improves glycaemic control in patients with type 2 diabetes compared with either monotherapy: a randomized controlled trial" Diabetes Obes Metab 2009; 11 (6): 611-622.
AstraZeneca "Clinical study protocol - SAVOR: saxagliptin assessment of vascular outcomes recorded in patients with diabetes mellitus" October 2009: 149 pages.