Functional imaging of localized prostate cancer aggressiveness using 11C-acetate PET/CT and 1H-MR spectroscopy

Journal of Nuclear Medicine

Volumn 51, Issue 11, 2010, Pages 1676-1683

  Jambor, Ivan ^a,b   Borra, Ronald ^a,c   Kemppainen, Jukka ^a,c   Lepomäki, Virva ^a,c   Parkkola, Riitta ^a,c   Dean, Kirsti ^a,c   Alanen, Kalle ^c   Arponen, Eveliina ^a   Nurmi, Martti ^c   Aronen, Hannu J ^a,c   Minn, Heikki ^a,c  

^a UNIVERSITY OF TURKU   (Finland)

^b Faculty of Natural Sciences   (Slovakia)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

11C acetate; PET CT; Prostate cancer; Proton MR spectroscopy

Indexed keywords

ACETIC ACID C 11; CHOLINE; CITRIC ACID; CONTRAST MEDIUM; CREATINE; POLYAMINE; PROSTATE SPECIFIC ANTIGEN;

ADULT; AGED; ARTICLE; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER LOCALIZATION; CANCER SIZE; CANCER SURGERY; CLINICAL ARTICLE; CLINICAL ASSESSMENT; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC IMAGING; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; GLEASON SCORE; HIGH RISK POPULATION; HISTOPATHOLOGY; HUMAN; IMAGE QUALITY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROGNOSIS; PROSPECTIVE STUDY; PROSTATE; PROSTATE ADENOCARCINOMA; PROSTATE BIOPSY; PROSTATE CANCER; PROSTATECTOMY; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; STANDARDIZED UPTAKE VALUE; TRANSRECTAL ULTRASONOGRAPHY; TRANSRECTAL ULTRASOUND GUIDED PROSTATE BIOPSY; TUMOR VOLUME;

ACETATES; AGED; CARBON; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; PROSTATE-SPECIFIC ANTIGEN; PROSTATIC NEOPLASMS; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, X-RAY COMPUTED;

EID: 79851485460     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.110.078667     Document Type: Article

References (25)

1. Dennis LK, Resnick MI. Analysis of recent trends in prostate cancer incidence and mortality. Prostate. 2000;42:247-252. (Pubitemid 30104567)
2. Presti JC Jr, Hricak H, Narayan PA, Shinohara K, White S, Carroll PR. Local staging of prostatic carcinoma: comparison of transrectal sonography and endorectal MR imaging. AJR. 1996;166:103-108. (Pubitemid 26010231)
3. Weinreb JC, Blume JD, Coakley FV, et al. Prostate cancer: sextant localization at MR imaging and MR spectroscopic imaging before prostatectomy - results of ACRIN prospective multi-institutional clinicopathologic study. Radiology. 2009;251:122-133.
4. Vilanova JC, Comet J, Barcelo-Vidal C, et al. Peripheral zone prostate cancer in patients with elevated PSA levels and low free-to-total PSA ratio: detection with MR imaging and MR spectroscopy. Radiology. 2009;253:135-143.
5. Costouros NG, Coakley FV, Westphalen AC, et al. Diagnosis of prostate cancer in patients with an elevated prostate-specific antigen level: role of endorectal MRI and MR spectroscopic imaging. AJR. 2007;188:812-816.
6. Hricak H, Choyke PL, Eberhardt SC, Leibel SA, Scardino PT. Imaging prostate cancer: a multidisciplinary perspective. Radiology. 2007;243:28-53. (Pubitemid 46579693)
7. Liu IJ, Zafar MB, Lai YH, Segall GM, Terris MK. Fluorodeoxyglucose positron emission tomography studies in diagnosis and staging of clinically organ-confined prostate cancer. Urology. 2001;57:108-111. (Pubitemid 32065829)
8. Sandblom G, Sorensen J, Lundin N, Haggman M, Malmstrom PU. Positron emission tomography with 11C-acetate for tumor detection and localization in patients with prostate-specific antigen relapse after radical prostatectomy. Urology. 2006;67:996-1000. (Pubitemid 43956436)
9. Oyama N, Miller TR, Dehdashti F, et al. 11C-acetate PET imaging of prostate cancer: detection of recurrent disease at PSA relapse. J Nucl Med. 2003;44:549-555. (Pubitemid 39663421)
10. Wachter S, Tomek S, Kurtaran A, et al. 11C-acetate positron emission tomography imaging and image fusion with computed tomography and magnetic resonance imaging in patients with recurrent prostate cancer. J Clin Oncol. 2006;24:2513-2519. (Pubitemid 46630628)
11. 11C]choline PET for detection of metastases of prostate cancer. Nuklearmedizin. 2003;42:25-30.
12. Kelloff GJ, Choyke P, Coffey DS. Challenges in clinical prostate cancer: role of imaging. AJR. 2009;192:1455-1470.
13. Morris MJ, Scher HI. 11C-acetate PET imaging in prostate cancer. Eur J Nucl Med Mol Imaging. 2007;34:181-184. (Pubitemid 46147500)
14. 11C-acetate as a PET radio-pharmaceutical for imaging fatty acid synthase expression in prostate cancer. J Nucl Med. 2008;49:327-334.
15. Yoshimoto M, Waki A, Yonekura Y, et al. Characterization of acetate metabolism in tumor cells in relation to cell proliferation: acetate metabolism in tumor cells. Nucl Med Biol. 2001;28:117-122. (Pubitemid 32276075)
16. 11C]acetate: an agent for the study of myocardial metabolism by positron emission tomography. Int J Appl Radiat Isot. 1982;33:505-512.
17. Seppala J, Seppanen M, Arponen E, Lindholm P, Minn H. Carbon-11 acetate PET/CT based dose escalated IMRT in prostate cancer. Radiother Oncol. 2009;93:234-240.
18. 11C] acetate in normal prostate and benign prostatic hyperplasia: comparison with prostate cancer. Eur J Nucl Med Mol Imaging. 2002;29:1492-1495.
19. Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med. 1993;30:672-679. (Pubitemid 23360802)
20. Mazaheri Y, Shukla-Dave A, Hricak H, et al. Prostate cancer: identification with combined diffusion-weighted MR imaging and 3D 1H MR spectroscopic imaging - correlation with pathologic findings. Radiology. 2008;246:480-488.
21. Ahmed HU. The index lesion and the origin of prostate cancer. N Engl J Med. 2009;361:1704-1706.
22. Oyama N, Akino H, Kanamaru H, et al. 11C-acetate PET imaging of prostate cancer. J Nucl Med. 2002;43:181-186. (Pubitemid 34151040)
23. Reinsberg SA, Payne GS, Riches SF, et al. Combined use of diffusion-weighted MRI and 1H MR spectroscopy to increase accuracy in prostate cancer detection. AJR. 2007;188:91-98. (Pubitemid 46012494)
24. Heijmink SW, Scheenen TW, van Lin EN, et al. Changes in prostate shape and volume and their implications for radiotherapy after introduction of endorectal balloon as determined by MRI at 3T. Int J Radiat Oncol Biol Phys. 2009;73:1446-1453.
25. Yamaguchi T, Lee J, Uemura H, et al. Prostate cancer: a comparative study of 11C-choline PET and MR imaging combined with proton MR spectroscopy. Eur J Nucl Med Mol Imaging. 2005;32:742-748. (Pubitemid 41125415)