Characterizing sudden death and dead-in-bed syndrome in Type 1 diabetes: Analysis from two childhood-onset Type 1 diabetes registries

Diabetic Medicine

Volumn 28, Issue 3, 2011, Pages 293-300

  Secrest, A M ^a   Becker, D J ^b   Kelsey, S F ^a   LaPorte, R E ^a   Orchard, T J ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

^b CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

Author keywords

Dead in bed syndrome; Mortality; Sudden death; Type 1 diabetes

Indexed keywords

HEMOGLOBIN A1C; INSULIN;

ADULT; ARTICLE; BODY MASS; CARDIOMYOPATHY; CAUSE OF DEATH; DEAD IN BED SYNDROME; DIABETIC COMA; FEMALE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; ONSET AGE; SUDDEN DEATH;

ADULT; ANALYSIS OF VARIANCE; AUSTRALIA; CAUSE OF DEATH; DEATH, SUDDEN; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; MALE; MIDDLE AGED; NORWAY; REGISTRIES; RISK FACTORS; SWEDEN; SYNDROME;

EID: 79851472834     PISSN: 07423071     EISSN: 14645491     Source Type: Journal    
DOI: 10.1111/j.1464-5491.2010.03154.x     Document Type: Article

References (30)

1. Tattersall RB, Gill GV. Unexplained deaths of Type 1 diabetic patients. Diabet Med 1991; 8: 49-58.
2. Dahlquist G, Kallen B. Mortality in childhood-onset type 1 diabetes: a population-based study. Diabetes Care 2005; 28: 2384-2387.
3. Borch-Johnsen K, Helweg-Larsen K. Sudden death and human insulin: is there a link? Diabet Med 1993; 10: 255-259.
4. Sartor G, Dahlquist G. Short-term mortality in childhood-onset insulin-dependent diabetes mellitus: a high frequency of unexpected deaths in bed. Diabet Med 1995; 12: 607-611.
5. Thordarson H, Sovik O. Dead-in-bed syndrome in young diabetic patients in Norway. Diabet Med 1995; 12: 782-787.
6. Tu E, Twigg SM, Duflou J, Semsarian C. Causes of death in young Australians with type1 diabetes: a review of coronial postmortem examinations. Med J Aust 2008; 188: 699-702.
7. Wibell L, Nystrom L, Ostman J, Arnqvist H, Blohme G, Lithner F et al. Increased mortality in diabetes during the first 10years of the disease. A population-based study (DISS) in Swedish adults 15-34years old at diagnosis. J Intern Med 2001; 249: 263-270.
8. Koltin D, Daneman D. Dead-in-bed syndrome - a diabetes nightmare. Pediatr Diabetes 2008; 9: 504-507.
9. Edge JA, Ford-Adams ME, Dunger DB. Causes of death in children with insulin-dependent diabetes 1990-1996. Arch Dis Child 1999; 81: 318-323.
10. Weston PJ, Gill GV. Is undetected autonomic dysfunction responsible for sudden death in Type1 diabetes mellitus? The 'dead-in-bed' syndrome revisited. Diabet Med 1999; 16: 626-631.
11. Tu E, Twigg SM, Semsarian C. Sudden death in type 1 diabetes: The mystery of the 'dead-in-bed' syndrome. Int J Cardiol 2010; 138: 91-93.
12. Harris ND, Heller SR. Sudden death in young patients with Type 1 diabetes: a consequence of disease, treatment or both? Diabet Med 1999; 16: 623-625.
13. Heller S. Dead in bed. Diabet Med 1999; 16: 782-785.
14. Heller SR. Abnormalities of the electrocardiogram during hypoglycaemia: the cause of the dead-in-bed syndrome? Int J Clin Pract Suppl 2002; 129: 27-32.
15. Lawrence IG, Weston PJ, Bennett MA, McNally PG, Burden AC, Thurston H. Is impaired baroreflex sensitivity a predictor or cause of sudden death in insulin-dependent diabetes mellitus? Diabet Med 1997; 14: 82-85.
16. McNally PG, Lawrence IG, Panerai RB, Weston PJ, Thurston H. Sudden death in type 1 diabetes. Diabetes Obes Metab 1999; 1: 151-158.
17. Dorman JS, LaPorte RE, Kuller LH, Cruickshanks KJ, Orchard TJ, Wagener DK et al. The Pittsburgh insulin-dependent diabetes mellitus (IDDM) morbidity and mortality study. Mortality results. Diabetes 1984; 33: 271-276.
18. Diabetes Epidemiology Research International Mortality Study Group. International evaluation of cause-specific mortality and IDDM. Diabetes Care 1991; 14: 55-60.
19. Nishimura R, LaPorte RE, Dorman JS, Tajima N, Becker D, Orchard TJ. Mortality trends in type 1 diabetes. The Allegheny County (Pennsylvania) Registry 1965-1999. Diabetes Care 2001; 24: 823-827.
20. Orchard TJ, Dorman JS, Maser RE, Becker DJ, Ellis D, LaPorte RE et al. Factors associated with avoidance of severe complications after 25years of IDDM. Pittsburgh Epidemiology of Diabetes Complications Study I. Diabetes Care 1990; 13: 741-747.
21. Hodges M, Salerno D, Erlien D. Bazett's QT correction reviewed-evidence that a linear QT correction for heart is better. J Am Coll Cardiol 1983; 1: 694.
22. Warnick GR, Albers JJ. Heparin-Mn2+ quantitation of high-density-lipoprotein cholesterol: an ultrafiltration procedure for lipemic samples. Clin Chem 1978; 24: 900-904.
23. Start RD, Barber C, Kaschula RO, Robinson RT. The 'dead in bed syndrome'-a cause of sudden death in Type 1 diabetes mellitus. Histopathology 2007; 51: 843-845.
24. Gill GV, Woodward A, Casson IF, Weston PJ. Cardiac arrhythmia and nocturnal hypoglycaemia in type 1 diabetes-the 'dead in bed' syndrome revisited. Diabetologia 2009; 52: 42-45.
25. Woodward A, Weston P, Casson IF, Gill GV. Nocturnal hypoglycaemia in type 1 diabetes-frequency and predictive factors. Q J Med 2009; 102: 603-607.
26. Gale EA, Tattersall RB. Unrecognised nocturnal hypoglycaemia in insulin-treated diabetics. Lancet 1979; 1: 1049-1052.
27. Tanenberg RJ, Newton CA, Drake AJ. Confirmation of hypoglycemia in the 'dead-in-bed' syndrome as captured by a retrospective continuous glucose monitoring system. Endocr Pract 2010; 16: 244-248.
28. Shen WK, Edwards WD, Hammill SC, Bailey KR, Ballard DJ, Gersh BJ. Sudden unexpected nontraumatic death in 54 young adults: a 30-year population-based study. Am J Cardiol 1995; 76: 148-152.
29. Eckart RE, Scoville SL, Campbell CL, Shry EA, Stajduhar KC, Potter RN et al. Sudden death in young adults: a 25-year review of autopsies in military recruits. Ann Intern Med 2004; 141: 829-834.
30. Vaartjes I, Hendrix A, Hertogh EM, Grobbee DE, Doevendans PA, Mosterd A et al. Sudden death in persons younger than 40years of age: incidence and causes. Eur J Cardiovasc Prev Rehabil 2009; 16: 592-596.