Self-adjuvanting multicomponent cancer vaccine candidates combining per-glycosylated muc1 glycopeptides and the toll-like receptor 2 agonist pam3CysSer

Angewandte Chemie - International Edition

Volumn 50, Issue 7, 2011, Pages 1635-1639

  Wilkinson, Brendan L ^a   Day, Stephanie ^b   Malins, Lara R ^a   Apostolopoulos, Vasso ^b   Payne, Richard J ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b BURNET INSTITUTE   (Australia)

Author keywords

antibodies; glycopeptides; mucina 1; solid phase peptide synthesis; vaccines

Indexed keywords

ANTIBODY TITERS; CANCER VACCINE; GLYCOPEPTIDES; GLYCOSYLATED; HIGH YIELD; IMMUNOADJUVANTS; MUC1 GLYCOPEPTIDES; MUCINA 1; MULTICOMPONENTS; MURINE MODEL; PENTAFLUOROPHENYL; SOLID-PHASE PEPTIDE SYNTHESIS; TOLL-LIKE RECEPTOR 2;

ANTIBODIES; ESTERIFICATION; ESTERS; SUGARS; VACCINES;

PEPTIDES;

2,3 BIS (PALMITOYLOXY) 2 PROPYL N PALMITOYL CYSTEINYLSERINE; 2,3-BIS-(PALMITOYLOXY)-2-PROPYL-N-PALMITOYL-CYSTEINYLSERINE; CANCER VACCINE; DIPEPTIDE; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; LIPOPROTEIN; MUCIN 1; TOLL LIKE RECEPTOR 2;

AMINO ACID SEQUENCE; ANIMAL; ARTICLE; C57BL MOUSE; CHEMISTRY; DRUG POTENTIATION; GLYCOSYLATION; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOUSE; SYNTHESIS; TUMOR CELL LINE;

ADJUVANTS, IMMUNOLOGIC; AMINO ACID SEQUENCE; ANIMALS; CANCER VACCINES; CELL LINE, TUMOR; DIPEPTIDES; GLYCOSYLATION; HUMANS; IMMUNOGLOBULIN G; LIPOPROTEINS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUCIN-1; TOLL-LIKE RECEPTOR 2;

EID: 79851470018     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201006115     Document Type: Article

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