Critical age windows for neurodevelopmental psychiatric disorders: Evidence from animal models

Neurotoxicity Research

Volumn 19, Issue 2, 2011, Pages 286-307

  Marco, Eva M ^a   MacRì, Simone ^a   Laviola, Giovanni ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

Adolescent; Childhood; Infant; Mental health; Pregnancy; Stress

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CANNABINOID 1 RECEPTOR; CORTICOTROPIN; CORTICOTROPIN RELEASING FACTOR; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; DYSBINDIN; INTERLEUKIN 1BETA; METHYLPHENIDATE; MU OPIATE RECEPTOR; NEU DIFFERENTIATION FACTOR; NEUROLIGIN; REELIN; SEROTONIN 2A RECEPTOR;

ADOLESCENCE; AGE; ARTICLE; ATTENTION DEFICIT DISORDER; AUTISM; BIPOLAR DISORDER; BRAIN DEVELOPMENT; BRAIN MATURATION; EARLY LIFE STRESS; EMOTIONALITY; ENVIRONMENTAL ENRICHMENT; GENETIC SUSCEPTIBILITY; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMOBILIZATION STRESS; MAJOR DEPRESSION; MATERNAL DEPRIVATION; MENTAL DISEASE; NERVE CELL PLASTICITY; NEWBORN HYPOXIA; NONHUMAN; PATHOGENESIS; PRENATAL EXPOSURE; PRENATAL STRESS; PRIORITY JOURNAL; RISK FACTOR; SCHIZOPHRENIA; SOCIAL BEHAVIOR;

AGE FACTORS; ANIMALS; CRITICAL PERIOD (PSYCHOLOGY); DISEASE MODELS, ANIMAL; EVIDENCE-BASED MEDICINE; FEMALE; HUMANS; MENTAL DISORDERS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RISK FACTORS; STRESS, PSYCHOLOGICAL;

ANIMALIA; RODENTIA;

EID: 79751531983     PISSN: 10298428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12640-010-9205-z     Document Type: Article

References (257)

1. H Abe N Hidaka C Kawagoe K Odagiri Y Watanabe T Ikeda Y Ishizuka H Hashiguchi R Takeda T Nishimori Y Ishida 2007 Prenatal psychological stress causes higher emotionality, depression-like behavior, and elevated activity in the hypothalamo-pituitary-adrenal axis Neurosci Res 59 145 151 1:CAS:528:DC%2BD2sXhtVOgsL7O 17658641 10.1016/j.neures.2007.06.1465 (Pubitemid 47440106)
2. A Abi-Dargham 2007 Alterations of serotonin transmission in schizophrenia Int Rev Neurobiol 78 133 164 1:CAS:528:DC%2BD2sXmt1Gmt70%3D 17349860 10.1016/S0074-7742(06)78005-9
3. M Acosta V Gallo ML Batshaw 2002 Brain development and the ontogeny of developmental disabilities Adv Pediatr 49 1 57 12214769
4. W Adriani G Laviola 2004 Windows of vulnerability to psychopathology and therapeutic strategy in the adolescent rodent model Behav Pharmacol 15 341 352 1:STN:280:DC%2BD2cvpvFOitg%3D%3D 15343057 10.1097/00008877-200409000-00005 (Pubitemid 39238344)
5. W Adriani S Spijker V Deroche-Gamonet G Laviola M Le Moal AB Smit PV Piazza 2003 Evidence for enhanced neurobehavioral vulnerability to nicotine during periadolescence in rats J Neurosci 23 4712 4716 1:CAS:528: DC%2BD3sXkslOksLw%3D 12805310 (Pubitemid 36706199)
6. W Adriani D Giannakopoulou Z Bokulic B Jernej E Alleva G Laviola 2006 Response to novelty, social and self-control behaviors, in rats exposed to neonatal anoxia: modulatory effects of an enriched environment Psychopharmacology (Berl) 184 155 165 1:CAS:528:DC%2BD28XksVOitA%3D%3D 10.1007/s00213-005-0223-0 (Pubitemid 43083652)
7. W Adriani D Leo D Greco M Rea U di Porzio G Laviola C Perrone-Capano 2006 Methylphenidate administration to adolescent rats determines plastic changes on reward-related behavior and striatal gene expression Neuropsychopharmacology 31 1946 1956 1:CAS:528:DC%2BD28XotFKltLY%3D 16319916 10.1038/sj.npp.1300962
8. W Adriani R Canese F Podo G Laviola 2007 1H MRS-detectable metabolic brain changes and reduced impulsive behavior in adult rats exposed to methylphenidate during adolescence Neurotoxicol Teratol 29 116 125 1:CAS:528:DC%2BD2sXhs1Slsrg%3D 17196789 10.1016/j.ntt.2006.11.010 (Pubitemid 46205168)
9. O Agid B Shapira J Zislin M Ritsner B Hanin H Murad T Troudart M Bloch U Heresco-Levy B Lerer 1999 Environment and vulnerability to major psychiatric illness: a case control study of early parental loss in major depression, bipolar disorder and schizophrenia Mol Psychiatr 4 163 172 1:STN:280: DyaK1M3itlWntQ%3D%3D 10.1038/sj.mp.4000473 (Pubitemid 29163979)
10. H Akil 2005 Stressed and depressed Nat Med 11 116 118 1:CAS:528:DC%2BD2MXpvF2gtA%3D%3D 15692589 10.1038/nm0205-116 (Pubitemid 40321340)
11. E Alleva 1993 Assessment of aggressive behavior in rodents Methods Neurosci 14 111 137
12. SL Andersen 2003 Trajectories of brain development: point of vulnerability or window of opportunity? Neurosci Biobehav Rev 27 3 18 12732219 10.1016/S0149-7634(03)00005-8 (Pubitemid 36535387)
13. SL Andersen MH Teicher 2008 Stress, sensitive periods and maturational events in adolescent depression Trends Neurosci 31 183 191 1:CAS:528: DC%2BD1cXksVags78%3D 18329735 10.1016/j.tins.2008.01.004
14. SL Andersen MH Teicher 2009 Desperately driven and no brakes: developmental stress exposure and subsequent risk for substance abuse Neurosci Biobehav R 33 516 524 10.1016/j.neubiorev.2008.09.009
15. Andrews G, Pine DS, Hobbs MJ, Anderson TM, Sunderland M (2009) Neurodevelopmental disorders: cluster 2 of the proposed meta-structure for DSM-V and ICD-11. Psychol Med 1-11
16. DJ Angelini MT Verklan 2009 Complications during the intrapartum and newborn period J Perinatal Neonatal Nurs 23 1 2
17. DL Bellinger C Lubahn D Lorton 2008 Maternal and early life stress effects on immune function: relevance to immunotoxicology J Immunotoxicol 5 419 444 1:CAS:528:DC%2BD1MXhsFSitbY%3D 19404876 10.1080/15476910802483415
18. H Beydoun AF Saftlas 2008 Physical and mental health outcomes of prenatal maternal stress in human and animal studies: a review of recent evidence Paediatr Perinatal Epidemiol 22 438 466 10.1111/j.1365-3016.2008.00951.x
19. E Bezard CE Gross MC Fournier S Dovero B Bloch M Jaber 1999 Absence of MPTP-induced neuronal death in mice lacking the dopamine transporter Exp Neurol 155 268 273 1:CAS:528:DyaK1MXhs1Smu70%3D 10072302 10.1006/exnr.1998.6995 (Pubitemid 29124720)
20. J Biederman 2005 Attention-deficit/hyperactivity disorder: a selective overview Biol Psychiatr 57 1215 1220 10.1016/j.biopsych.2004.10.020 (Pubitemid 40798537)
21. M Biscaia S Marin B Fernandez EM Marco M Rubio C Guaza E Ambrosio MP Viveros 2003 Chronic treatment with CP 55, 940 during the peri-adolescent period differentially affects the behavioural responses of male and female rats in adulthood Psychopharmacology (Berl) 170 301 308 1:CAS:528:DC%2BD3sXovVOhs74%3D 10.1007/s00213-003-1550-7 (Pubitemid 37491610)
22. SJ Blakemore 2008 The social brain in adolescence Nat Rev Neurosci 9 267 277 1:CAS:528:DC%2BD1cXjsFCks7g%3D 18354399 10.1038/nrn2353 (Pubitemid 351430833)
23. P Boksa 2008 Maternal infection during pregnancy and schizophrenia J Psychiatry Neurosci 33 183 185 18592037 (Pubitemid 351692417)
24. CA Bolanos M Barrot O Berton D Wallace-Black EJ Nestler 2003 Methylphenidate treatment during pre- and periadolescence alters behavioral responses to emotional stimuli at adulthood Biol Psychiatr 54 1317 1329 1:CAS:528:DC%2BD3sXpvVWqtrY%3D 10.1016/S0006-3223(03)00570-5 (Pubitemid 37522155)
25. J Borrell JM Vela A Arevalo-Martin E Molina-Holgado C Guaza 2002 Prenatal immune challenge disrupts sensorimotor gating in adult rats. Implications for the etiopathogenesis of schizophrenia Neuropsychopharmacology 26 204 215 1:CAS:528:DC%2BD38XktFWrtw%3D%3D 11790516 10.1016/S0893-133X(01)00360-8 (Pubitemid 34093083)
26. Bowlby J (1969) Attachment and loss, Attachment. Basic Books, New York
27. J Bowlby 1988 Developmental psychiatry comes of age Am J Psychiatr 145 1 10 1:STN:280:DyaL1c7gsValtg%3D%3D 3276225 (Pubitemid 18026489)
28. WT Boyce BJ Ellis 2005 Biological sensitivity to context: I. An evolutionary-developmental theory of the origins and functions of stress reactivity Dev Psychopathol 17 271 301 16761546 10.1017/S0954579405050145 (Pubitemid 41388314)
29. RJ Braga G Petrides I Figueira 2004 Anxiety disorders in schizophrenia Compr Psychiatr 45 460 468 10.1016/j.comppsych.2004.07.009 (Pubitemid 39446811)
30. CL Brandon M Marinelli LK Baker FJ White 2001 Enhanced reactivity and vulnerability to cocaine following methylphenidate treatment in adolescent rats Neuropsychopharmacology 25 651 661 1:CAS:528:DC%2BD3MXnslCjsb8%3D 11682248 10.1016/S0893-133X(01)00281-0 (Pubitemid 32995947)
31. AS Brown 2006 Prenatal infection as a risk factor for schizophrenia Schizophr Bull 32 200 202 16469941 10.1093/schbul/sbj052
32. AS Brown ES Susser 2002 In utero infection and adult schizophrenia Ment Retard Dev Disabil Res Rev 8 51 57 11921387 10.1002/mrdd.10004 (Pubitemid 34754494)
33. SA Brown SF Tapert 2004 Adolescence and the trajectory of alcohol use: basic to clinical studies Ann NY Acad Sci 1021 234 244 15251893 10.1196/annals.1308.028 (Pubitemid 38879629)
34. M Butz F Worgotter A van Ooyen 2009 Activity-dependent structural plasticity Brain Res Rev 60 287 305 19162072 10.1016/j.brainresrev.2008.12.023
35. B Buwalda C Nyakas HJ Vosselman PG Luiten 1995 Effects of early postnatal anoxia on adult learning and emotion in rats Behav Brain Res 67 85 90 1:STN:280:DyaK2M3mslelug%3D%3D 7748505 10.1016/0166-4328(94)00108-R
36. M Cannon PB Jones RM Murray 2002 Obstetric complications and schizophrenia: historical and meta-analytic review Am J Psychiatr 159 1080 1092 12091183 10.1176/appi.ajp.159.7.1080 (Pubitemid 34743246)
37. M Caputa J Rogalska K Wentowska A Nowakowska 2005 Perinatal asphyxia, hyperthermia and hyperferremia as factors inducing behavioural disturbances in adulthood: a rat model Behav Brain Res 163 246 256 16038989 10.1016/j.bbr.2005. 05.015 (Pubitemid 41138059)
38. WA Carlezon Jr SD Mague SL Andersen 2003 Enduring behavioral effects of early exposure to methylphenidate in rats Biol Psychiatr 54 1330 1337 1:CAS:528:DC%2BD3sXpvVWqtrc%3D 10.1016/j.biopsych.2003.08.020 (Pubitemid 37522156)
39. BJ Casey RM Jones TA Hare 2008 The adolescent brain Ann NY Acad Sci 1124 111 126 1:STN:280:DC%2BD1c3ktV2rsw%3D%3D 18400927 10.1196/annals.1440.010 (Pubitemid 351506787)
40. P Casolini AR Zuena C Cinque P Matteucci GS Alema W Adriani G Carpinelli F Santoro E Alleva P Bosco F Nicoletti G Laviola A Catalani 2005 Sub-neurotoxic neonatal anoxia induces subtle behavioural changes and specific abnormalities in brain group-I metabotropic glutamate receptors in rats J Neurochem 95 137 145 1:CAS:528:DC%2BD2MXhtVygs7fI 16181418 10.1111/j.1471-4159.2005.03349.x (Pubitemid 41384432)
41. A Catalani M Marinelli S Scaccianoce R Nicolai LA Muscolo A Porcu L Koranyi PV Piazza L Angelucci 1993 Progeny of mothers drinking corticosterone during lactation has lower stress-induced corticosterone secretion and better cognitive performance Brain Res 624 209 215 1:CAS:528:DyaK3sXmsVWmsbc%3D 8252393 10.1016/0006-8993(93)90079-3 (Pubitemid 23281821)
42. A Catalani P Casolini S Scaccianoce FR Patacchioli P Spinozzi L Angelucci 2000 Maternal corticosterone during lactation permanently affects brain corticosteroid receptors, stress response and behaviour in rat progeny Neuroscience 100 319 325 1:CAS:528:DC%2BD3cXmslKmsbo%3D 11008169 10.1016/S0306-4522(00)00277-3
43. Y Chen M Hillefors-Berglund M Herrera-Marschitz B Bjelke J Gross K Andersson G von Euler 1997 Perinatal asphyxia induces long-term changes in dopamine D1, D2, and D3 receptor binding in the rat brain Exp Neurol 146 74 80 1:CAS:528:DyaK2sXkslOit78%3D 9225740 10.1006/exnr.1997.6497 (Pubitemid 27319721)
44. F Cirulli N Francia A Berry L Aloe E Alleva SJ Suomi 2009 Early life stress as a risk factor for mental health: role of neurotrophins from rodents to non-human primates Neurosci Biobehav Rev 33 573 585 1:CAS:528: DC%2BD1MXjt1akt7o%3D 18817811 10.1016/j.neubiorev.2008.09.001
45. CL Coe M Kramer C Kirschbaum P Netter E Fuchs 2002 Prenatal stress diminishes the cytokine response of leukocytes to endotoxin stimulation in juvenile rhesus monkeys J Clin Endocrinol Metab 87 675 681 1:CAS:528: DC%2BD38XhsVSisrw%3D 11836303 10.1210/jc.87.2.675 (Pubitemid 34158236)
46. FR D'Amato S Cabib S Puglisi-Allegra FR Patacchioli G Cigliana S Maccari L Angelucci 1992 Effects of acute and repeated exposure to stress on the hypothalamo-pituitary-adrenocortical activity in mice during postnatal development Horm Behav 26 474 485 1478632 10.1016/0018-506X(92)90015-N
47. M Dabkowska J Rybakowski 1994 Stress, depression and schizophrenia in view of psychoimmunology Psychiatr Pol 28 23 32 1:STN:280:DyaK2cznslGrtw%3D%3D 7522333
48. M Darnaudery S Maccari 2008 Epigenetic programming of the stress response in male and female rats by prenatal restraint stress Brain Res Rev 57 571 585 1:CAS:528:DC%2BD1cXjs1Sru7w%3D 18164765 10.1016/j.brainresrev.2007.11.004
49. M de Haan JS Wyatt S Roth F Vargha-Khadem D Gadian M Mishkin 2006 Brain and cognitive-behavioural development after asphyxia at term birth Dev Sci 9 350 358 16764608 10.1111/j.1467-7687.2006.00499.x (Pubitemid 43855814)
50. de Irala J, Ruiz-Canela M, Martinez-Gonzalez MA (2005) Causal relationship between cannabis use and psychotic symptoms or depression. Should we wait and see? A public health perspective. Med Sci Monit 11:RA355-RA358 (Pubitemid 43138432)
51. ER de Kloet 2003 Hormones, brain and stress Endocr Regul 37 51 68 12932191 (Pubitemid 37420023)
52. ER de Kloet RH Derijk OC Meijer 2007 Therapy insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression? Nat Clin Pract Endocrinol Metab 3 168 179 17237843 10.1038/ncpendmet0403 1:CAS:528:DC%2BD2sXhvVWrsb0%3D (Pubitemid 46146969)
53. B Dean S Sundram R Bradbury E Scarr D Copolov 2001 Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use Neuroscience 103 9 15 1:CAS:528:DC%2BD3MXislaqsrw%3D 11311783 10.1016/S0306-4522(00)00552-2 (Pubitemid 32304342)
54. MJ Decker GE Hue WM Caudle GW Miller GL Keating DB Rye 2003 Episodic neonatal hypoxia evokes executive dysfunction and regionally specific alterations in markers of dopamine signaling Neuroscience 117 417 425 1:CAS:528:DC%2BD3sXhsVChsL8%3D 12614682 10.1016/S0306-4522(02)00805-9 (Pubitemid 36259756)
55. M Di Forti PD Morrison A Butt RM Murray 2007 Cannabis use and psychiatric and cognitive disorders: the chicken or the egg? Curr Opin Psychiatr 20 228 234 (Pubitemid 46588294)
56. DE Dluzen LI Anderson JL McDermott J Kucera JM Walro 2002 Striatal dopamine output is compromised within +/- BDNF mice Synapse 43 112 117 1:CAS:528:DC%2BD38XjtVKisQ%3D%3D 11754489 10.1002/syn.10027 (Pubitemid 34028494)
57. Doremus-Fitzwater TL, Varlinskaya EI Spear LP (2009) Motivational systems in adolescence: Possible implications for age differences in substance abuse and other risk-taking behaviors. Brain Cogn 72:114-123
58. JB Dwyer SC McQuown FM Leslie 2009 The dynamic effects of nicotine on the developing brain Pharmacol Therapeut 122 125 139 1:CAS:528:DC%2BD1MXkslyktr4%3D 10.1016/j.pharmthera.2009.02.003
59. IJ Elenkov GP Chrousos 2002 Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity Ann N Y Acad Sci 966 290 303 1:CAS:528:DC%2BD38XlvVWmur0%3D 12114286 10.1111/j.1749-6632.2002.tb04229.x (Pubitemid 34729188)
60. BF El-Khodor P Boksa 1997 Long-term reciprocal changes in dopamine levels in prefrontal cortex versus nucleus accumbens in rats born by Caesarean section compared to vaginal birth Exp Neurol 145 118 129 1:CAS:528:DyaK2sXjvVyitb0%3D 9184115 10.1006/exnr.1997.6437 (Pubitemid 27244286)
61. BF El-Khodor P Boksa 1998 Birth insult increases amphetamine-induced behavioral responses in the adult rat Neuroscience 87 893 904 1:CAS:528:DyaK1cXmtVWrsLg%3D 9759977 10.1016/S0306-4522(98)00194-8 (Pubitemid 28400360)
62. B El-Khodor P Boksa 2001 Caesarean section birth produces long term changes in dopamine D1 receptors and in stress-induced regulation of D3 and D4 receptors in the rat brain Neuropsychopharmacology 25 423 439 1:CAS:528:DC%2BD3MXmtFSqsLo%3D 11522470 10.1016/S0893-133X(01)00228-7 (Pubitemid 32777791)
63. BA Ellenbroek AR Cools 1995 Maternal separation reduces latent inhibition in the conditioned taste aversion paradigm Neurosci Res Commun 17 27 33
64. BA Ellenbroek AR Cools 2002 Early maternal deprivation and prepulse inhibition: the role of the postdeprivation environment Pharmacol Biochem Behav 73 177 184 1:CAS:528:DC%2BD38XksFKksbc%3D 12076737 10.1016/S0091-3057(02)00794-3 (Pubitemid 34667030)
65. BA Ellenbroek PT van den Kroonenberg AR Cools 1998 The effects of an early stressful life event on sensorimotor gating in adult rats Schizophr Res 30 251 260 1:STN:280:DyaK1c3ltFChtg%3D%3D 9589519 10.1016/S0920-9964(97)00149-7 (Pubitemid 28189557)
66. BA Ellenbroek NM de Bruin PT van Den Kroonenburg EL van Luijtelaar AR Cools 2004 The effects of early maternal deprivation on auditory information processing in adult Wistar rats Biol Psychiatr 55 701 707 10.1016/j.biopsych. 2003.10.024 (Pubitemid 38376181)
67. BA Ellenbroek N Derks HJ Park 2005 Early maternal deprivation retards neurodevelopment in Wistar rats Stress 8 247 257 16423713 10.1080/ 10253890500404634 (Pubitemid 43163257)
68. M Ellgren SM Spano YL Hurd 2007 Adolescent cannabis exposure alters opiate intake and opioid limbic neuronal populations in adult rats Neuropsychopharmacology 32 607 615 1:CAS:528:DC%2BD2sXhslWhu7w%3D 16823391 10.1038/sj.npp.1301127
69. PL Ellickson JS Tucker DJ Klein 2001 High-risk behaviors associated with early smoking: results from a 5-year follow-up J Adolesc Health 28 465 473 1:STN:280:DC%2BD3M3ps1aqsw%3D%3D 11377990 10.1016/S1054-139X(00)00202-0 (Pubitemid 32506784)
70. BJ Ellis MJ Essex WT Boyce 2005 Biological sensitivity to context: II. Empirical explorations of an evolutionary-developmental theory Dev Psychopathol 17 303 328 16761547 10.1017/S0954579405050157 (Pubitemid 41388315)
71. RM Escorihuela A Fernandez-Teruel A Zapata JF Nunez A Tobena 1993 Flumazenil prevents the anxiolytic effects of diazepam, alprazolam and adinazolam on the early acquisition of two-way active avoidance Pharmacol Res 28 53 58 1:CAS:528:DyaK3sXlvFGms74%3D 8234145 10.1006/phrs.1993.1109 (Pubitemid 23252428)
72. JL Evenden CN Ryan 1999 The pharmacology of impulsive behaviour in rats VI: the effects of ethanol and selective serotonergic drugs on response choice with varying delays of reinforcement Psychopharmacology (Berl) 146 413 421 1:CAS:528:DyaK1MXnvVansLY%3D 10.1007/PL00005486 (Pubitemid 29513281)
73. BJ Everitt TW Robbins 2005 Neural systems of reinforcement for drug addiction: from actions to habits to compulsion Nat Neurosci 8 1481 1489 1:CAS:528:DC%2BD2MXhtFCrurbI 16251991 10.1038/nn1579 (Pubitemid 41573659)
74. D Faeh B Viswanathan A Chiolero W Warren P Bovet 2006 Clustering of smoking, alcohol drinking and cannabis use in adolescents in a rapidly developing country BMC Public Health 6 169 16803621 10.1186/1471-2458-6-169 (Pubitemid 44403515)
75. X Fan DC Goff DC Henderson 2007 Inflammation and schizophrenia Expert Rev Neurother 7 789 796 1:CAS:528:DC%2BD2sXnt1KgsLo%3D 17610386 10.1586/14737175.7.7.789 (Pubitemid 47037719)
76. SH Fatemi TD Folsom 2009 The neurodevelopmental hypothesis of schizophrenia, revisited Schizophr Bull 35 528 548 19223657 10.1093/schbul/ sbn187
77. WS Fenton 2001 Comorbid conditions in schizophrenia Curr Opin Psychiatr 14 17 23 10.1097/00001504-200101000-00004 (Pubitemid 32505717)
78. A Fernandez-Teruel RM Escorihuela B Castellano B Gonzalez A Tobena 1997 Neonatal handling and environmental enrichment effects on emotionality, novelty/reward seeking, and age-related cognitive and hippocampal impairments: focus on the Roman rat lines Behav Genet 27 513 526 1:STN:280: DyaK1c7js1ygtQ%3D%3D 9476360 10.1023/A:1021400830503 (Pubitemid 28098959)
79. A Fernandez-Teruel P Driscoll L Gil R Aguilar A Tobena RM Escorihuela 2002 Enduring effects of environmental enrichment on novelty seeking, saccharin and ethanol intake in two rat lines (RHA/Verh and RLA/Verh) differing in incentive-seeking behavior Pharmacol Biochem Behav 73 225 231 1:CAS:528:DC%2BD38XksFKktr0%3D 12076741 10.1016/S0091-3057(02)00784-0 (Pubitemid 34667034)
80. A Fernandez-Teruel L Gimenez-Llort RM Escorihuela L Gil R Aguilar T Steimer A Tobena 2002 Early-life handling stimulation and environmental enrichment: are some of their effects mediated by similar neural mechanisms? Pharmacol Biochem Behav 73 233 245 1:CAS:528:DC%2BD38XksFKktro%3D 12076742 10.1016/S0091-3057(02)00787-6 (Pubitemid 34667035)
81. KC Fone MV Porkess 2008 Behavioural and neurochemical effects of post-weaning social isolation in rodents-relevance to developmental neuropsychiatric disorders Neurosci Biobehav R 32 1087 1102 1:CAS:528: DC%2BD1cXotlCgs7k%3D 10.1016/j.neubiorev.2008.03.003
82. ME Fortier R Joober GN Luheshi P Boksa 2004 Maternal exposure to bacterial endotoxin during pregnancy enhances amphetamine-induced locomotion and startle responses in adult rat offspring J Psychiatr Res 38 335 345 15003440 10.1016/j.jpsychires.2003.10.001 (Pubitemid 38299172)
83. C Fox Z Merali C Harrison 2006 Therapeutic and protective effect of environmental enrichment against psychogenic and neurogenic stress Behav Brain Res 175 1 8 1:CAS:528:DC%2BD28XhtFOjtrzK 16970997 10.1016/j.bbr.2006.08.016 (Pubitemid 44691931)
84. DD Francis MJ Meaney 1999 Maternal care and the development of stress responses Curr Opin Neurobiol 9 128 134 1:CAS:528:DyaK1MXhvVWiurg%3D 10072372 10.1016/S0959-4388(99)80016-6 (Pubitemid 29084099)
85. DD Francis J Diorio PM Plotsky MJ Meaney 2002 Environmental enrichment reverses the effects of maternal separation on stress reactivity J Neurosci 22 7840 7843 1:CAS:528:DC%2BD38Xnt12lt78%3D 12223535 (Pubitemid 35379088)
86. Freud S (1918) From the history of an infantile neurosis. Hogarth Press, London
87. M Fritzsche 2001 Are cannabinoid receptor knockout mice animal models for schizophrenia? Med Hypotheses 56 638 643 1:CAS:528:DC%2BD3MXltlegu7s%3D 11399112 10.1054/mehy.2000.1261
88. JN Giedd 2008 The teen brain: insights from neuroimaging J Adolesc Health 42 335 343 18346658 10.1016/j.jadohealth.2008.01.007 (Pubitemid 351381455)
89. JN Giedd FM Lalonde MJ Celano SL White GL Wallace NR Lee RK Lenroot 2009 Anatomical brain magnetic resonance imaging of typically developing children and adolescents J Am Acad Child Adolesc Psychiatr 48 465 470 10.1097/CHI. 0b013e31819f2715
90. J Goggi IA Pullar SL Carney HF Bradford 2002 Modulation of neurotransmitter release induced by brain-derived neurotrophic factor in rat brain striatal slices in vitro Brain Res 941 34 42 1:CAS:528: DC%2BD38XjvVSgs78%3D 12031545 10.1016/S0006-8993(02)02505-2 (Pubitemid 34603281)
91. II Gottesman DR Hanson 2005 Human development: biological and genetic processes Annu Rev Psychol 56 263 286 15709936 10.1146/annurev.psych.56.091103. 070208 (Pubitemid 40300786)
92. AA Gotz V Stefanski 2007 Psychosocial maternal stress during pregnancy affects serum corticosterone, blood immune parameters and anxiety behaviour in adult male rat offspring Physiol Behav 90 108 115 17067641 10.1016/j.physbeh. 2006.09.014 1:CAS:528:DC%2BD2sXhvVSntg%3D%3D (Pubitemid 44918012)
93. K Greaves-Lord AC Huizink AJ Oldehinkel J Ormel FC Verhulst RF Ferdinand 2009 Baseline cortisol measures and developmental pathways of anxiety in early adolescence Acta psychiatrica Scandinavica 120 178 186 1:CAS:528: DC%2BD1MXhtFaisb3E 19485962 10.1111/j.1600-0447.2009.01402.x
94. A Grech J Van Os PB Jones SW Lewis RM Murray 2005 Cannabis use and outcome of recent onset psychosis Eur Psychiatr 20 349 353 10.1016/j.eurpsy. 2004.09.013 (Pubitemid 40978562)
95. AI Green CM Canuso MJ Brenner JD Wojcik 2003 Detection and management of comorbidity in patients with schizophrenia Psychiatr Clin North Am 26 115 139 12683263 10.1016/S0193-953X(02)00014-X (Pubitemid 36384351)
96. S Grojean H Schroeder G Pourie C Charriaut-Marlangue V Koziel D Desor P Vert JL Daval 2003 Histopathological alterations and functional brain deficits after transient hypoxia in the newborn rat pup: a long term follow-up Neurobiol Dis 14 265 278 1:CAS:528:DC%2BD3sXot1Grt78%3D 14572448 10.1016/S0969-9961(03) 00082-2 (Pubitemid 37311290)
97. O Guillin A Abi-Dargham M Laruelle 2007 Neurobiology of dopamine in schizophrenia Int Rev Neurobiol 78 1 39 1:CAS:528:DC%2BD2sXmt1Gmtrg%3D 17349856 10.1016/S0074-7742(06)78001-1
98. W Hall L Degenhardt 2008 Cannabis use and the risk of developing a psychotic disorder World Psychiatr 7 68 71
99. Harlow HF, Harlow MK (1965) The affectional systems. In: Schrier AM, Harlow HF, Stollnitz, F (eds) Behavior of nonhuman primates. Academic Press, New York and London, pp 287-334
100. HF Harlow GL Rowland GA Griffin 1964 The effect of total social deprivation on the development of monkey behavior Psychiatr Res Rep Am Psychiatr Assoc 19 116 135 1:STN:280:DyaF2M%2FjslSlsA%3D%3D 14232649
101. C Heim CB Nemeroff 2001 The role of childhood trauma in the neurobiology of mood and anxiety disorders: preclinical and clinical studies Biol Psychiatr 49 1023 1039 1:STN:280:DC%2BD3MznsVCgtQ%3D%3D 10.1016/S0006-3223(01)01157-X (Pubitemid 32595461)
102. C Heim DJ Newport T Mletzko AH Miller CB Nemeroff 2008 The link between childhood trauma and depression: insights from HPA axis studies in humans Psychoneuroendocrinology 33 693 710 1:CAS:528:DC%2BD1cXosVyjsbk%3D 18602762 10.1016/j.psyneuen.2008.03.008
103. L Iuvone MC Geloso E Dell'Anna 1996 Changes in open field behavior, spatial memory, and hippocampal parvalbumin immunoreactivity following enrichment in rats exposed to neonatal anoxia Exp Neurol 139 25 33 1:STN:280:DyaK283hsl2ktg%3D%3D 8635565 10.1006/exnr.1996.0077 (Pubitemid 26160374)
104. EB Johansen H Aase A Meyer T Sagvolden 2002 Attention-deficit/ hyperactivity disorder (ADHD) behaviour explained by dysfunctioning reinforcement and extinction processes Behav Brain Res 130 37 45 11864716 10.1016/S0166-4328(01)00434-X (Pubitemid 34195319)
105. MH Johnson 2005 Sensitive periods in functional brain development: problems and prospects Dev Psychobiol 46 287 292 15772965 10.1002/dev.20057 (Pubitemid 40592657)
106. DB Kandel K Yamaguchi K Chen 1992 Stages of progression in drug involvement from adolescence to adulthood: further evidence for the gateway theory J Stud Alcohol 53 447 457 1:STN:280:DyaK3s%2Fit1Oitg%3D%3D 1405637
107. AE Kelley T Schochet CF Landry 2004 Risk taking and novelty seeking in adolescence: introduction to part I Ann NY Acad Sci 1021 27 32 15251871 10.1196/annals.1308.003 (Pubitemid 38879607)
108. KS Kendler K Sheth CO Gardner CA Prescott 2002 Childhood parental loss and risk for first-onset of major depression and alcohol dependence: the time-decay of risk and sex differences Psychol Med 32 1187 1194 1:STN:280:DC%2BD38nmtVyltg%3D%3D 12420888 (Pubitemid 35243976)
109. JI Koenig GI Elmer PD Shepard PR Lee C Mayo B Joy E Hercher DL Brady 2005 Prenatal exposure to a repeated variable stress paradigm elicits behavioral and neuroendocrinological changes in the adult offspring: potential relevance to schizophrenia Behav Brain Res 156 251 261 15582111 10.1016/j.bbr.2004.05.030 (Pubitemid 39576065)
110. O Kofman 2002 The role of prenatal stress in the etiology of developmental behavioural disorders Neurosci Biobehav Rev 26 457 470 1:CAS:528:DC%2BD38XmsVerurk%3D 12204192 10.1016/S0149-7634(02)00015-5 (Pubitemid 36163348)
111. A Kolevzon R Gross A Reichenberg 2007 Prenatal and perinatal risk factors for autism: a review and integration of findings Arch Pediatr Adolesc Med 161 326 333 17404128 10.1001/archpedi.161.4.326 (Pubitemid 46556362)
112. RM Kostrzewa TA Reader L Descarries 1998 Serotonin neural adaptations to ontogenetic loss of dopamine neurons in rat brain J Neurochem 70 889 898 1:CAS:528:DyaK1cXht1yrt7s%3D 9489707 10.1046/j.1471-4159.1998.70030889.x (Pubitemid 28113620)
113. AM La Greca MJ Prinstein MD Fetter 2001 Adolescent peer crowd affiliation: linkages with health-risk behaviors and close friendships J Pediatr Psychol 26 131 143 1:STN:280:DC%2BD3M7mtFyhtQ%3D%3D 11259515 10.1093/jpepsy/26.3.131 (Pubitemid 32374482)
114. S Lai H Lai JB Page CB McCoy 2000 The association between cigarette smoking and drug abuse in the United States J Addict Dis 19 11 24 1:STN:280:DC%2BD3MzgsVamug%3D%3D 11110061 10.1300/J069v19n04-02
115. G Laviola W Adriani ML Terranova G Gerra 1999 Psychobiological risk factors for vulnerability to psychostimulants in human adolescents and animal models Neurosci Biobehav Rev 23 993 1010 1:CAS:528:DyaK1MXmvVKhsrw%3D 10580313 10.1016/S0149-7634(99)00032-9 (Pubitemid 29502404)
116. G Laviola S Macrì S Morley-Fletcher W Adriani 2003 Risk-taking behavior in adolescent mice: psychobiological determinants and early epigenetic influence Neurosci Biobehav Rev 27 19 31 12732220 10.1016/S0149-7634(03)00006-X (Pubitemid 36535388)
117. G Laviola W Adriani M Rea L Aloe E Alleva 2004 Social withdrawal, neophobia, and stereotyped behavior in developing rats exposed to neonatal asphyxia Psychopharmacology (Berl) 175 196 205 1:CAS:528:DC%2BD2cXnt1Grsbs%3D 10.1007/s00213-004-1800-3 (Pubitemid 39222350)
118. G Laviola M Rea S Morley-Fletcher S Di Carlo A Bacosi R De Simone M Bertini R Pacifici 2004 Beneficial effects of enriched environment on adolescent rats from stressed pregnancies Eur J Neurosci 20 1655 1664 15355333 10.1111/j.1460-9568.2004.03597.x (Pubitemid 39274049)
119. G Laviola AJ Hannan S Macrì M Solinas M Jaber 2008 Effects of enriched environment on animal models of neurodegenerative diseases and psychiatric disorders Neurobiol Dis 31 159 168 18585920 10.1016/j.nbd.2008.05. 001
120. G Laviola E Ognibene E Romano W Adriani F Keller 2009 Gene-environment interaction during early development in the heterozygous reeler mouse: clues for modelling of major neurobehavioral syndromes Neurosci Biobehav Rev 33 560 572 1:CAS:528:DC%2BD1MXjt1akt70%3D 18845182 10.1016/j.neubiorev.2008.09.006
121. AJ Law Q Pei M Walker H Gordon-Andrews CS Weickert J Feldon CR Pryce PJ Harrison 2009 Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder Neuropsychopharmacology 34 1381 1394 1:CAS:528:DC%2BD1MXksFagu7Y%3D 18615010 10.1038/npp.2008.106
122. MJ Lazinski AK Shea M Steiner 2008 Effects of maternal prenatal stress on offspring development: a commentary Arch Womens Ment Health 11 363 375 18975045 10.1007/s00737-008-0035-4
123. JH Lee HJ Kim JG Kim V Ryu BT Kim DW Kang JW Jahng 2007 Depressive behaviors and decreased expression of serotonin reuptake transporter in rats that experienced neonatal maternal separation Neurosci Res 58 32 39 1:CAS:528:DC%2BD2sXkvFGjsrw%3D 17298851 10.1016/j.neures.2007.01.008 (Pubitemid 46678488)
124. PR Lee DL Brady RA Shapiro DM Dorsa JI Koenig 2007 Prenatal stress generates deficits in rat social behavior: reversal by oxytocin Brain Res 1156 152 167 1:CAS:528:DC%2BD2sXmvVOhsr0%3D 17540347 10.1016/j.brainres.2007.04.042 (Pubitemid 46920515)
125. J Lehmann CR Pryce AL Jongen-Relo T Stohr HH Pothuizen J Feldon 2002 Comparison of maternal separation and early handling in terms of their neurobehavioral effects in aged rats Neurobiol Aging 23 457 466 11959408 10.1016/S0197-4580(01)00320-7 (Pubitemid 34312029)
126. V Lemaire M Koehl M Le Moal DN Abrous 2000 Prenatal stress produces learning deficits associated with an inhibition of neurogenesis in the hippocampus Proc Natl Acad Sci USA 97 11032 11037 1:CAS:528:DC%2BD3cXnt1ahtr0%3D 11005874 10.1073/pnas.97.20.11032
127. V Lemaire S Lamarque M Le Moal PV Piazza DN Abrous 2006 Postnatal stimulation of the pups counteracts prenatal stress-induced deficits in hippocampal neurogenesis Biol Psychiatr 59 786 792 10.1016/j.biopsych.2005.11. 009
128. D Leo W Adriani C Cavaliere G Cirillo EM Marco E Romano U di Porzio M Papa C Perrone-Capano G Laviola 2009 Methylphenidate to adolescent rats drives enduring changes of accumbal Htr7 expression: implications for impulsive behavior and neuronal morphology Genes Brain Behav 8 356 368 1:CAS:528:DC%2BD1MXmtFeis70%3D 19243449 10.1111/j.1601-183X.2009.00486.x
129. S Levine 1957 Infantile experience and resistance to physiological stress Science 126 405 1:STN:280:DyaG1c%2FgvFyqsg%3D%3D 13467220 10.1126/science.126. 3270.405
130. S Levine 2000 Influence of psychological variables on the activity of the hypothalamic-pituitary-adrenal axis Eur J Pharmacol 405 149 160 1:CAS:528:DC%2BD3cXnt1Sit7Y%3D 11033322 10.1016/S0014-2999(00)00548-3
131. S Levine 2005 Developmental determinants of sensitivity and resistance to stress Psychoneuroendocrinology 30 939 946 15958281 10.1016/j.psyneuen.2005.03. 013 (Pubitemid 40982476)
132. S Levine M Alpert GW Lewis 1957 Infantile experience and the maturation of the pituitary adrenal axis Science 126 1347 1:STN:280:DyaG1c%2FjvVahtg%3D%3D 13495470 10.1126/science.126.3287.1347
133. S Levine DM Huchton SG Wiener P Rosenfeld 1991 Time course of the effect of maternal deprivation on the hypothalamic-pituitary-adrenal axis in the infant rat Dev Psychobiol 24 547 558 1:CAS:528:DyaK38XhvVyhtb8%3D 1773913 10.1002/dev.420240803
134. FM Leweke D Koethe 2008 Cannabis and psychiatric disorders: it is not only addiction Addict Biol 13 264 275 18482435 10.1111/j.1369-1600.2008.00106.x (Pubitemid 351692982)
135. FM Leweke A Giuffrida U Wurster HM Emrich D Piomelli 1999 Elevated endogenous cannabinoids in schizophrenia Neuroreport 10 1665 1669 1:CAS:528:DyaK1MXksFaltLc%3D 10501554 10.1097/00001756-199906030-00008 (Pubitemid 29354290)
136. D Liu J Diorio B Tannenbaum C Caldji D Francis A Freedman S Sharma D Pearson PM Plotsky MJ Meaney 1997 Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress Science 277 1659 1662 1:CAS:528:DyaK2sXmtVSgsL0%3D 9287218 10.1126/science.277.5332.1659 (Pubitemid 27446227)
137. E Llorente ML Brito P Machado MC Gonzalez 2002 Effect of prenatal stress
138. Llorente R, Arranz L, Marco EM, Moreno E, Puerto M, Guaza C, De la FM, Viveros MP (2007) Early maternal deprivation and neonatal single administration with a cannabinoid agonist induce long-term sex-dependent psychoimmunoendocrine effects in adolescent rats. Psychoneuroendocrinology 32:636-650 (Pubitemid 47018322)
139. R Llorente A Llorente-Berzal S Petrosino EM Marco C Guaza C Prada M Lopez-Gallardo V Di Marzo MP Viveros 2008 Gender-dependent cellular and biochemical effects of maternal deprivation on the hippocampus of neonatal rats: a possible role for the endocannabinoid system Dev Neurobiol 68 1334 1347 1:CAS:528:DC%2BD1cXhtFKlt7fO 18666205 10.1002/dneu.20666
140. CA Lockwood CG Menter J Moggi-Cecchi AW Keyser 2007 Extended male growth in a fossil hominin species Science 318 1443 1446 1:CAS:528:DC%2BD2sXhtlGmtLnK 18048687 10.1126/science.1149211 (Pubitemid 350208953)
141. Lorenz K (1937/1957) The conception of instinctive behavior. In: Schiller CH (ed) Instinctive behavior. International Universities Press, New York, pp 129-175
142. CA Lowry MW Hale AK Evans J Heerkens DR Staub PJ Gasser A Shekhar 2008 Serotonergic systems, anxiety, and affective disorder: focus on the dorsomedial part of the dorsal raphe nucleus Ann N Y Acad Sci 1148 86 94 19120094 10.1196/annals.1410.004
143. S Maccari S Morley-Fletcher 2007 Effects of prenatal restraint stress on the hypothalamus-pituitary-adrenal axis and related behavioural and neurobiological alterations Psychoneuroendocrinology 32 Suppl 1 S10 S15 17651905 10.1016/j.psyneuen.2007.06.005 1:CAS:528:DC%2BD2sXovFeiur4%3D (Pubitemid 47211641)
144. S Maccari M Darnaudery S Morley-Fletcher AR Zuena C Cinque O Van Reeth 2003 Prenatal stress and long-term consequences: implications of glucocorticoid hormones Neurosci Biobehav Rev 27 119 127 1:CAS:528:DC%2BD3sXjsVGnurg%3D 12732228 10.1016/S0149-7634(03)00014-9 (Pubitemid 36535394)
145. M Mackowiak A Chocyk K Markowicz-Kula K Wedzony 2004 Neurogenesis in the adult brain Pol J Pharmacol 56 673 687 15662080 (Pubitemid 40287469)
146. S Macrì F Chiarotti H Wurbel 2008 Maternal separation and maternal care act independently on the development of HPA responses in male rats Behav Brain Res 191 227 234 18468700 10.1016/j.bbr.2008.03.031 1:CAS:528: DC%2BD1cXmtlSgtr8%3D
147. S Macrì G Laviola 2004 Single episode of maternal deprivation and adult depressive profile in mice: interaction with cannabinoid exposure during adolescence Behav Brain Res 154 231 238 15302129 10.1016/j.bbr.2004.02.009 (Pubitemid 39070470)
148. S Macrì H Wurbel 2006 Developmental plasticity of HPA and fear responses in rats: a critical review of the maternal mediation hypothesis Horm Behav 50 667 680 16890940 10.1016/j.yhbeh.2006.06.015 1:CAS:528: DC%2BD28Xht1aju7nL (Pubitemid 44738850)
149. S Macrì GJ Mason H Wurbel 2004 Dissociation in the effects of neonatal maternal separations on maternal care and the offspring's HPA and fear responses in rats Eur J Neurosci 20 1017 1024 15305870 10.1111/j.1460-9568.2004. 03541.x (Pubitemid 39141308)
150. S Macrì P Pasquali LT Bonsignore S Pieretti F Cirulli F Chiarotti G Laviola 2007 Moderate neonatal stress decreases within-group variation in behavioral, immune and HPA responses in adult mice PLoS One 2 e1015 17925863 10.1371/journal.pone.0001015 1:CAS:528:DC%2BD1cXjs1yrsw%3D%3D (Pubitemid 351560151)
151. S Macrì S Spinelli W Adriani J Dee Higley G Laviola 2007 Early adversity and alcohol availability persistently modify serotonin and hypothalamic-pituitary-adrenal-axis metabolism and related behavior: what experimental research on rodents and primates can tell us Neurosci Biobehav Rev 31 172 180 16956661 10.1016/j.neubiorev.2006.06.026 1:CAS:528: DC%2BD2sXltFSguw%3D%3D (Pubitemid 46074136)
152. S Macrì O Granstrem M Shumilina FJ Antunes Gomes dos Santos A Berry L Saso G Laviola 2009 Resilience and vulnerability are dose-dependently related to neonatal stressors in mice Horm Behav 56 391 398 19632235 10.1016/j.yhbeh.2009.07.006 1:CAS:528:DC%2BD1MXht1GmurnL
153. C Maneru C Junque F Botet M Tallada J Guardia 2001 Neuropsychological long-term sequelae of perinatal asphyxia Brain Inj 15 1029 1039 1:STN:280:DC%2BD3Mnmslehsg%3D%3D 11712949 10.1080/02699050110074178 (Pubitemid 33120961)
154. B Marchetti MC Morale N Testa C Tirolo S Caniglia S Amor CD Dijkstra N Barden 2001 Stress, the immune system and vulnerability to degenerative disorders of the central nervous system in transgenic mice expressing glucocorticoid receptor antisense RNA Brain Res Brain Res Rev 37 259 272 1:CAS:528:DC%2BD3MXovF2jtbk%3D 11744091 10.1016/S0165-0173(01)00130-8 (Pubitemid 34020736)
155. EM Marco O Granstrem E Moreno R Llorente W Adriani G Laviola MP Viveros 2007 Subchronic nicotine exposure in adolescence induces long-term effects on hippocampal and striatal cannabinoid-CB1 and mu-opioid receptors in rats Eur J Pharmacol 557 37 43 1:CAS:528:DC%2BD2sXhtVKntr0%3D 17174300 10.1016/j.ejphar. 2006.11.013 (Pubitemid 46135558)
156. EM Marco W Adriani R Llorente G Laviola MP Viveros 2009 Detrimental psychophysiological effects of early maternal deprivation in adolescent and adult rodents: altered responses to cannabinoid exposure Neurosci Biobehav Rev 33 498 507 1:CAS:528:DC%2BD1MXjt1akt78%3D 18457877 10.1016/j.neubiorev.2008.03. 008
157. K Matthews TW Robbins 2003 Early experience as a determinant of adult behavioural responses to reward: the effects of repeated maternal separation in the rat Neurosci Biobehav Rev 27 45 55 12732222 10.1016/S0149-7634(03)00008-3 (Pubitemid 36535389)
158. WJ McBride RL Bell ZA Rodd WN Strother JM Murphy 2005 Adolescent alcohol drinking and its long-range consequences. Studies with animal models Recent Dev Alcohol 17 123 142 15789863 10.1007/0-306-48626-1-6
159. MJ Meaney 2001 Maternal care, gene expression, and the transmission of individual differences in stress reactivity across generations Annu Rev Neurosci 24 1161 1192 1:CAS:528:DC%2BD3MXls1Shsbs%3D 11520931 10.1146/annurev.neuro.24. 1.1161 (Pubitemid 32695257)
160. MJ Meaney J Diorio D Francis S Weaver J Yau K Chapman JR Seckl 2000 Postnatal handling increases the expression of cAMP-inducible transcription factors in the rat hippocampus: the effects of thyroid hormones and serotonin J Neurosci 20 3926 3935 1:CAS:528:DC%2BD3cXjtlKqtro%3D 10804232 (Pubitemid 30266253)
161. A Meijer 1985 Child psychiatric sequelae of maternal war stress Acta Psychiatr Scand 72 505 511 1:STN:280:DyaL28%2FpvFymsA%3D%3D 2417452 10.1111/j.1600-0447.1985.tb02647.x
162. E Merlot D Couret W Otten 2008 Prenatal stress, fetal imprinting and immunity Brain Behav Immun 22 42 51 1:CAS:528:DC%2BD2sXhsVWjtLzP 17716859 10.1016/j.bbi.2007.05.007 (Pubitemid 350225652)
163. U Meyer J Feldon SH Fatemi 2009 In-vivo rodent models for the experimental investigation of prenatal immune activation effects in neurodevelopmental brain disorders Neurosci Biobehav Rev 33 1061 1079 1:CAS:528:DC%2BD1MXotFOiu7c%3D 19442688 10.1016/j.neubiorev.2009.05.001
164. GF Michel AN Tyler 2005 Critical period: a history of the transition from questions of when, to what, to how Dev Psychobiol 46 156 162 15772973 10.1002/dev.20058 (Pubitemid 40592648)
165. J Mill A Petronis 2008 Pre- and peri-natal environmental risks for attention-deficit hyperactivity disorder (ADHD): the potential role of epigenetic processes in mediating susceptibility J Child Psychol Psychiatry 49 1020 1030 18492038 10.1111/j.1469-7610.2008.01909.x
166. VA Mittal LM Ellman TD Cannon 2008 Gene-environment interaction and covariation in schizophrenia: the role of obstetric complications Schizophr Bull 34 1083 1094 18635675 10.1093/schbul/sbn080
167. MC Moffett A Vicentic M Kozel P Plotsky DD Francis MJ Kuhar 2007 Maternal separation alters drug intake patterns in adulthood in rats Biochem Pharmacol 73 321 330 1:CAS:528:DC%2BD2sXht1Snug%3D%3D 16962564 10.1016/j.bcp.2006.08.003 (Pubitemid 44958363)
168. AG Montoya R Sorrentino SE Lukas BH Price 2002 Long-term neuropsychiatric consequences of "ecstasy" (MDMA): a review Harv Rev Psychiatr 10 212 220 (Pubitemid 34791184)
169. C Morgan H Fisher 2007 Environment and schizophrenia: environmental factors in schizophrenia: childhood trauma-a critical review Schizophr Bull 33 3 10 17105965 10.1093/schbul/sbl053 (Pubitemid 46026253)
170. S Morley-Fletcher M Darnaudery M Koehl P Casolini O Van Reeth S Maccari 2003 Prenatal stress in rats predicts immobility behavior in the forced swim test. Effects of a chronic treatment with tianeptine Brain Res 989 246 251 1:CAS:528:DC%2BD3sXnvFShtLw%3D 14556947 10.1016/S0006-8993(03)03293-1 (Pubitemid 37211429)
171. S Morley-Fletcher M Rea S Maccari G Laviola 2003 Environmental enrichment during adolescence reverses the effects of prenatal stress on play behaviour and HPA axis reactivity in rats Eur J Neurosci 18 3367 3374 14686910 10.1111/j.1460-9568.2003.03070.x (Pubitemid 38031062)
172. SS Moy JJ Nadler 2008 Advances in behavioral genetics: mouse models of autism Mol Psychiatr 13 4 26 1:CAS:528:DC%2BD2sXhsVegtLrN 10.1038/sj.mp.4002082 (Pubitemid 350275186)
173. N Muller M Riedel R Gruber M Ackenheil MJ Schwarz 2000 The immune system and schizophrenia. An integrative view Ann NY Acad Sci 917 456 467 1:CAS:528:DC%2BD3cXovFymsb0%3D 11268373 10.1111/j.1749-6632.2000.tb05410.x
174. CB Nemeroff MJ Owens 2009 The role of serotonin in the pathophysiology of depression: as important as ever Clin Chem 55 1578 1579 1:CAS:528: DC%2BD1MXptleisb8%3D 19498050 10.1373/clinchem.2009.123752
175. J Nithianantharajah AJ Hannan 2006 Enriched environments, experience-dependent plasticity and disorders of the nervous system Nat Rev Neurosci 7 697 709 1:CAS:528:DC%2BD28XotlCgtr0%3D 16924259 10.1038/nrn1970 (Pubitemid 44267494)
176. C Nocjar BL Roth EA Pehek 2002 Localization of 5-HT(2A) receptors on dopamine cells in subnuclei of the midbrain A10 cell group Neuroscience 111 163 176 1:CAS:528:DC%2BD38XivVSnsLs%3D 11955720 10.1016/S0306-4522(01)00593-0 (Pubitemid 34310459)
177. RS Nowakowski NL Hayes 1999 CNS development: an overview Dev Psychopathol 11 395 417 1:STN:280:DC%2BD3c%2FgtVCitA%3D%3D 10532616 10.1017/ S0954579499002126
178. K O'Donnell TG O'Connor V Glover 2009 Prenatal stress and neurodevelopment of the child: focus on the HPA axis and role of the placenta Dev Neurosci 31 285 292 19546565 10.1159/000216539 1:CAS:528: DC%2BD1MXnsFekurs%3D
179. M O'Shea ME Singh IS McGregor PE Mallet 2004 Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats J Psychopharmacol 18 502 508 15582916 10.1177/0269881104047277 (Pubitemid 39665118)
180. CM O'Tuathaigh D Babovic G O'Meara JJ Clifford DT Croke JL Waddington 2007 Susceptibility genes for schizophrenia: characterisation of mutant mouse models at the level of phenotypic behaviour Neurosci Biobehav Rev 31 60 78 16782199 10.1016/j.neubiorev.2006.04.002 1:CAS:528:DC%2BD28Xht12ksL%2FK (Pubitemid 44880074)
181. MJ Painter 1995 Animal models of perinatal asphyxia: contributions, contradictions, clinical relevance Semin Pediatr Neurol 2 37 56 1:STN:280:DyaK1c%2FosVamtQ%3D%3D 9422233 10.1016/S1071-9091(05)80004-X
182. PH Patterson 2007 Neuroscience. Maternal effects on schizophrenia risk Science 318 576 577 1:CAS:528:DC%2BD2sXht1CmtbfP 17962542 10.1126/science. 1150196 (Pubitemid 350017607)
183. PH Patterson 2009 Immune involvement in schizophrenia and autism: etiology, pathology and animal models Behav Brain Res 204 313 321 1:CAS:528:DC%2BD1MXhtVKns7jE 19136031 10.1016/j.bbr.2008.12.016
184. JD Penner AS Brown 2007 Prenatal infectious and nutritional factors and risk of adult schizophrenia Expert Rev Neurother 7 797 805 17610387 10.1586/14737175.7.7.797 (Pubitemid 47037720)
185. LO Pereira AC Strapasson PM Nabinger M Achaval CA Netto 2008 Early enriched housing results in partial recovery of memory deficits in female, but not in male, rats after neonatal hypoxia-ischemia Brain Res 1218 257 266 1:CAS:528:DC%2BD1cXnsFGitr0%3D 18514167 10.1016/j.brainres.2008.04.010
186. LO Pereira PM Nabinger AC Strapasson P Nardin CA Goncalves IR Siqueira CA Netto 2009 Long-term effects of environmental stimulation following hypoxia-ischemia on the oxidative state and BDNF levels in rat hippocampus and frontal cortex Brain Res 1247 188 195 1:CAS:528:DC%2BD1cXhsV2ns7jI 18992724 10.1016/j.brainres.2008.10.017
187. LJ Phillips PD McGorry B Garner KN Thompson C Pantelis SJ Wood G Berger 2006 Stress, the hippocampus and the hypothalamic-pituitary-adrenal axis: implications for the development of psychotic disorders Aust NZ J Psychiatr 40 725 741 (Pubitemid 44145215)
188. C Pickering L Gustafsson A Cebere I Nylander S Liljequist 2006 Repeated maternal separation of male Wistar rats alters glutamate receptor expression in the hippocampus but not the prefrontal cortex Brain Res 1099 101 108 1:CAS:528:DC%2BD28XntlWit7Y%3D 16784730 10.1016/j.brainres.2006.04.136 (Pubitemid 44080106)
189. BJ Piper 2007 A developmental comparison of the neurobehavioral effects of ecstasy (MDMA) Neurotoxicol Teratol 29 288 300 1:CAS:528:DC%2BD2sXjtVagt7c%3D 17174068 10.1016/j.ntt.2006.10.002 (Pubitemid 46400368)
190. PM Plotsky MJ Meaney 1993 Early, postnatal experience alters hypothalamic corticotropin-releasing factor (CRF) mRNA, median eminence CRF content and stress-induced release in adult rats Brain Res Mol Brain Res 18 195 200 1:CAS:528:DyaK3sXks1ems7o%3D 8497182 10.1016/0169-328X(93)90189-V
191. RJ Primus CK Kellogg 1989 Pubertal-related changes influence the development of environment-related social interaction in the male rat Dev Psychobiol 22 633 643 1:STN:280:DyaK3c%2Fgs1CitA%3D%3D 2792573 10.1002/dev.420220608 (Pubitemid 19221695)
192. CR Pryce J Feldon 2003 Long-term neurobehavioural impact of the postnatal environment in rats: manipulations, effects and mediating mechanisms Neurosci Biobehav Rev 27 57 71 12732223 10.1016/S0149-7634(03)00009-5 (Pubitemid 36535390)
193. TN Raju 1992 Some animal models for the study of perinatal asphyxia Biol Neonate 62 202 214 1:STN:280:DyaK3s%2Fkt1egsA%3D%3D 1420619 10.1159/000243873
194. S Rasmuson T Olsson BG Henriksson PA Kelly MC Holmes JR Seckl AH Mohammed 1998 Environmental enrichment selectively increases 5-HT1A receptor mRNA expression and binding in the rat hippocampus Brain Res Mol Brain Res 53 285 290 1:CAS:528:DyaK1cXlsFentQ%3D%3D 9473697 10.1016/S0169-328X(97)00317-3 (Pubitemid 28085464)
195. D Rice S Barone Jr 2000 Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models Environ Health Perspect 108 (Suppl 3) 511 533 10.2307/3454543 (Pubitemid 30466179)
196. F Rice I Jones A Thapar 2007 The impact of gestational stress and prenatal growth on emotional problems in offspring: a review Acta Psychiatr Scand 115 171 183 1:STN:280:DC%2BD2s7gsVSqsw%3D%3D 17302617 10.1111/j.1600-0447. 2006.00895.x
197. Rice F, Harold GT, Boivin J, van den Bree M, Hay DF, Thapar A (2009) The links between prenatal stress and offspring development and psychopathology: disentangling environmental and inherited influences. Psychol Med 1-11
198. M Roceri W Hendriks G Racagni BA Ellenbroek MA Riva 2002 Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus Mol Psychiatr 7 609 616 1:CAS:528:DC%2BD38XlsFWrsbo%3D 10.1038/sj.mp.4001036
199. MR Rosenzweig EL Bennett 1996 Psychobiology of plasticity: effects of training and experience on brain and behavior Behav Brain Res 78 57 65 1:STN:280:DyaK28zosFWkuw%3D%3D 8793038 10.1016/0166-4328(95)00216-2 (Pubitemid 26179783)
200. MR Rosenzweig EL Bennett M Hebert H Morimoto 1978 Social grouping cannot account for cerebral effects of enriched environments Brain Res 153 563 576 1:STN:280:DyaE1M%2Fit1Gisg%3D%3D 698794 10.1016/0006-8993(78)90340-2 (Pubitemid 9025581)
201. AM Rozeboom H Akil AF Seasholtz 2007 Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice Proc Natl Acad Sci USA 104 4688 4693 1:CAS:528:DC%2BD2sXjsFylu74%3D 17360585 10.1073/pnas.0606067104 (Pubitemid 47186286)
202. T Rubino D Parolaro 2008 Long lasting consequences of cannabis exposure in adolescence Mol Cell Endocrinol 286 S108 S113 1:CAS:528:DC%2BD1cXlslSjsLg%3D 18358595 10.1016/j.mce.2008.02.003
203. D Ruedi-Bettschen EM Pedersen J Feldon CR Pryce 2005 Early deprivation under specific conditions leads to reduced interest in reward in adulthood in Wistar rats Behav Brain Res 156 297 310 15582116 10.1016/j.bbr.2004.06.001 (Pubitemid 39576070)
204. O Rufini A Valanzano G Calamandrei 2001 Animal models of hypoxic-ischemic encephalopathy Ann Ist Super Sanita 37 561 566 1:STN:280:DC%2BD38zgsFagtQ%3D%3D 12046226
205. NN Sarkar 2008 The impact of intimate partner violence on women's reproductive health and pregnancy outcome J Obstet Gynaecol 28 266 271 1:STN:280:DC%2BD1cvgtFKntw%3D%3D 18569465 10.1080/01443610802042415 (Pubitemid 351873787)
206. N Sawamura A Sawa 2006 Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses Ann NY Acad Sci 1086 126 133 1:CAS:528:DC%2BD2sXhtVWhtLk%3D 17185511 10.1196/annals.1377.018 (Pubitemid 47084386)
207. A Scheepens G Wassink CE Blanco 2003 The effect of a global birth asphyxia on the ontogeny of BDNF and NGF protein expression in the juvenile brain Brain Res Dev Brain Res 140 215 221 1:CAS:528:DC%2BD3sXhtVCqsrY%3D 12586427 10.1016/S0165-3806(02)00608-9 (Pubitemid 36173979)
208. TS Schepis B Adinoff U Rao 2008 Neurobiological processes in adolescent addictive disorders Am J Addict 17 6 23 18214718 10.1080/10550490701756146 (Pubitemid 351156999)
209. OJ Schiepers MC Wichers M Maes 2005 Cytokines and major depression Prog Neuropsychopharmacol Biol Psychiatr 29 201 217 1:CAS:528:DC%2BD2MXptlCqsQ%3D%3D 10.1016/j.pnpbp.2004.11.003 (Pubitemid 40202906)
210. M Schmidt L Enthoven JH van Woezik S Levine ER de Kloet MS Oitzl 2004 The dynamics of the hypothalamic-pituitary-adrenal axis during maternal deprivation J Neuroendocrinol 16 52 57 1:CAS:528:DC%2BD2cXhtVCit70%3D 14962076 10.1111/j.1365-2826.2004.01123.x (Pubitemid 38159393)
211. M Schneider 2008 Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure Addict Biol 13 253 263 18482434 10.1111/j.1369-1600.2008.00110.x (Pubitemid 351692985)
212. M Schneider M Koch 2003 Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult rats Neuropsychopharmacology 28 1760 1769 1:CAS:528:DC%2BD3sXnsVyisLk%3D 12888772 10.1038/sj.npp.1300225 (Pubitemid 41070841)
213. TC Schneirla JS Rosenblatt 1963 "Critical Periods" in the Development of Behavior Science 139 1110 1115 1:STN:280:DC%2BC3cvktVKhsQ%3D%3D 17813013 10.1126/science.139.3559.1110
214. MJ Schwarz S Chiang N Muller M Ackenheil 2001 T-helper-1 and T-helper-2 responses in psychiatric disorders Brain Behav Immun 15 340 370 1:CAS:528:DC%2BD38Xit1ymsw%3D%3D 11782103 10.1006/brbi.2001.0647 (Pubitemid 34044520)
215. JP Scott 1962 Critical periods in behavioral development Science 138 949 958 1:STN:280:DyaF387osVCisA%3D%3D 13992547 10.1126/science.138.3544.949
216. J Scott Y McNeill J Cavanagh M Cannon R Murray 2006 Exposure to obstetric complications and subsequent development of bipolar disorder: systematic review Br J Psychiatr 189 3 11 10.1192/bjp.bp.105.010579 (Pubitemid 44023323)
217. A Shea C Walsh H Macmillan M Steiner 2005 Child maltreatment and HPA axis dysregulation: relationship to major depressive disorder and post traumatic stress disorder in females Psychoneuroendocrinology 30 162 178 1:CAS:528:DC%2BD2cXotlSmtL4%3D 15471614 10.1016/j.psyneuen.2004.07.001 (Pubitemid 39313113)
218. L Shi SH Fatemi RW Sidwell PH Patterson 2003 Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring J Neurosci 23 297 302 12514227 (Pubitemid 36050430)
219. LM Siqueira JS Brook 2003 Tobacco use as a predictor of illicit drug use and drug-related problems in Colombian youth J Adolesc Health 32 50 57 12507801 10.1016/S1054-139X(02)00534-7 (Pubitemid 36042812)
220. PD Skosnik L Spatz-Glenn S Park 2001 Cannabis use is associated with schizotypy and attentional disinhibition Schizophr Res 48 83 92 1:STN:280:DC%2BD3M7ovF2lsQ%3D%3D 11278156 10.1016/S0920-9964(00)00132-8 (Pubitemid 32241185)
221. TA Slotkin 2002 Nicotine and the adolescent brain: insights from an animal model Neurotoxicol Teratol 24 369 384 1:CAS:528:DC%2BD38XjsFygs7w%3D 12009492 10.1016/S0892-0362(02)00199-X (Pubitemid 34495468)
222. TA Slotkin EA MacKillop CL Rudder IT Ryde CA Tate FJ Seidler 2007 Permanent, sex-selective effects of prenatal or adolescent nicotine exposure, separately or sequentially, in rat brain regions: indices of cholinergic and serotonergic synaptic function, cell signaling, and neural cell number and size at 6 months of age Neuropsychopharmacology 32 1082 1097 1:CAS:528: DC%2BD2sXkt1Gqs7k%3D 17047666 10.1038/sj.npp.1301231 (Pubitemid 46631987)
223. Smotherman WP, Bell RW (1980) Maternal mediation of early experience. In: Smotherman WP, Bell RL (eds) Maternal influences and early behavior. Spectrum, New York, pp 201-210
224. FE Sondeijker RF Ferdinand AJ Oldehinkel H Tiemeier J Ormel FC Verhulst 2008 HPA-axis activity as a predictor of future disruptive behaviors in young adolescents Psychophysiology 45 398 404 18312496 10.1111/j.1469-8986.2008.00639. x (Pubitemid 351502496)
225. LP Spear 2000 The adolescent brain and age-related behavioral manifestations Neurosci Biobehav Rev 24 417 463 1:STN:280:DC%2BD3c3nvVagsg%3D%3D 10817843 10.1016/S0149-7634(00)00014-2 (Pubitemid 30243061)
226. DJ Stein 2008 Depression, anhedonia, and psychomotor symptoms: the role of dopaminergic neurocircuitry CNS Spectr 13 561 565 18622360
227. JM Stern SK Johnson 1990 Ventral somatosensory determinants of nursing behavior in Norway rats. I. Effects of variations in the quality and quantity of pup stimuli Physiol Behav 47 993 1011 1:STN:280:DyaK3czls1Knsg%3D%3D 2388953 10.1016/0031-9384(90)90026-Z (Pubitemid 20171702)
228. RD Strous Y Shoenfeld 2006 Schizophrenia, autoimmunity and immune system dysregulation: a comprehensive model updated and revisited J Autoimmun 27 71 80 1:CAS:528:DC%2BD28XhtVyksbrE 16997531 10.1016/j.jaut.2006.07.006 (Pubitemid 44528264)
229. J Suárez R Llorente SY Romero-Zerbo B Mateos FJ Bermudez-Silva FR de Fonseca MP Viveros 2009 Early maternal deprivation induces gender-dependent changes on the expression of hippocampal CB(1) and CB(2) cannabinoid receptors of neonatal rats Hippocampus 19 623 632 19115376 10.1002/hipo.20537 1:CAS:528:DC%2BD1MXpsVens70%3D
230. D Suchecki S Tufik 1997 Long-term effects of maternal deprivation on the corticosterone response to stress in rats Am J Physiol 273 R1332 R1338 1:STN:280:DyaK1c%2Fis1Kiuw%3D%3D 9362296
231. EJ Susman 2006 Psychobiology of persistent antisocial behavior: stress, early vulnerabilities and the attenuation hypothesis Neurosci Biobehav Rev 30 376 389 16239030 10.1016/j.neubiorev.2005.08.002 (Pubitemid 43230169)
232. NM Talge C Neal V Glover 2007 Antenatal maternal stress and long-term effects on child neurodevelopment: how and why? J Child Psychol Psychiatr 48 245 261 10.1111/j.1469-7610.2006.01714.x (Pubitemid 46372120)
233. MH Teicher A Tomoda SL Andersen 2006 Neurobiological consequences of early stress and childhood maltreatment: are results from human and animal studies comparable? Ann NY Acad Sci 1071 313 323 16891580 10.1196/annals.1364. 024 (Pubitemid 44126738)
234. ML Terranova G Laviola L de Acetis E Alleva 1998 A description of the ontogeny of mouse agonistic behavior J Comp Psychol 112 3 12 1:STN:280:DyaK1c7ovVGntg%3D%3D 9528111 10.1037/0735-7036.112.1.3 (Pubitemid 128458827)
235. M Tohmi N Tsuda Y Watanabe A Kakita H Nawa 2004 Perinatal inflammatory cytokine challenge results in distinct neurobehavioral alterations in rats: implication in psychiatric disorders of developmental origin Neurosci Res 50 67 75 1:CAS:528:DC%2BD2cXmt1Wrs70%3D 15288500 10.1016/j.neures.2004.05.010 (Pubitemid 39024303)
236. M Tuchscherer E Kanitz W Otten A Tuchscherer 2002 Effects of prenatal stress on cellular and humoral immune responses in neonatal pigs Vet Immunol Immunopathol 86 195 203 1:CAS:528:DC%2BD38XjsVSqtb0%3D 12007885 10.1016/S0165-2427(02)00035-1 (Pubitemid 34465749)
237. H Ujike Y Morita 2004 New perspectives in the studies on endocannabinoid and cannabis: cannabinoid receptors and schizophrenia J Pharmacol Sci 96 376 381 1:CAS:528:DC%2BD2MXisFGntQ%3D%3D 15613777 10.1254/jphs.FMJ04003X4 (Pubitemid 40144054)
238. DL Van den Hove HW Steinbusch A Scheepens WD Van de Berg LA Kooiman BJ Boosten J Prickaerts CE Blanco 2006 Prenatal stress and neonatal rat brain development Neuroscience 137 145 155 16242847 10.1016/j.neuroscience.2005.08.060 1:CAS:528:DC%2BD28XhsFGrtw%3D%3D (Pubitemid 43031482)
239. M van Handel H Swaab LS de Vries MJ Jongmans 2007 Long-term cognitive and behavioral consequences of neonatal encephalopathy following perinatal asphyxia: a review Eur J Pediatr 166 645 654 17426984 10.1007/s00431-007-0437-8 (Pubitemid 46800741)
240. HJ van Oers ER de Kloet S Levine 1997 Persistent, but paradoxical, effects on HPA regulation of infants maternally deprived at different ages Stress 1 249 262 9787249 10.3109/10253899709013745
241. H van Praag G Kempermann FH Gage 2000 Neural consequences of environmental enrichment Nat Rev Neurosci 1 191 198 11257907 10.1038/35044558 1:CAS:528:DC%2BD3MXivVSjsrY%3D
242. LJ Vanderschuren RJ Niesink JM Van Ree 1997 The neurobiology of social play behavior in rats Neurosci Biobehav Rev 21 309 326 1:CAS:528: DyaK2sXjvVOksLc%3D 9168267 10.1016/S0149-7634(96)00020-6 (Pubitemid 27225153)
243. J Vidal J Bie RA Granneman AE Wallinga JM Koolhaas B Buwalda 2007 Social stress during adolescence in Wistar rats induces social anxiety in adulthood without affecting brain monoaminergic content and activity Physiol behav 92 824 830 1:CAS:528:DC%2BD2sXhtlWqurnE 17651767 10.1016/j.physbeh.2007.06.004 (Pubitemid 350101672)
244. T Wakuda H Matsuzaki K Suzuki Y Iwata C Shinmura S Suda K Iwata S Yamamoto G Sugihara KJ Tsuchiya T Ueki K Nakamura D Nakahara N Takei N Mori 2008 Perinatal asphyxia reduces dentate granule cells and exacerbates methamphetamine-induced hyperlocomotion in adulthood PLoS One 3 e3648 18985150 10.1371/journal.pone.0003648 1:CAS:528:DC%2BD1cXhtlKhsbrO
245. IL Ward KE Stehm 1991 Prenatal stress feminizes juvenile play patterns in male rats Physiol Behav 50 601 605 1:STN:280:DyaK387ps1ajsw%3D%3D 1801016 10.1016/0031-9384(91)90552-Y
246. Y Watanabe S Hashimoto A Kakita H Takahashi J Ko M Mizuno T Someya PH Patterson H Nawa 2004 Neonatal impact of leukemia inhibitory factor on neurobehavioral development in rats Neurosci Res 48 345 353 1:CAS:528: DC%2BD2cXhtFCitb8%3D 15154680 10.1016/j.neures.2003.12.001 (Pubitemid 38220952)
247. IC Weaver N Cervoni FA Champagne AC D'Alessio S Sharma JR Seckl S Dymov M Szyf MJ Meaney 2004 Epigenetic programming by maternal behavior Nat Neurosci 7 847 854 1:CAS:528:DC%2BD2cXmtVamt7c%3D 15220929 10.1038/nn1276 (Pubitemid 38989508)
248. O Weininger 1954 Physiological damage under emotional stress as a function of early experience Science 119 285 286 1:STN:280: DyaG2c%2FlsFCjtA%3D%3D 13135523 10.1126/science.119.3087.285
249. O Weininger CW Mc RK Arima 1954 Gentling and weight gain in the albino rat Can J Psychol 8 147 151 1:STN:280:DyaG2M%2Fgt1Smsw%3D%3D 13190472
250. M Weinstock 2002 Can the behaviour abnormalities induced by gestational stress in rats be prevented or reversed? Stress 5 167 176 1:STN:280: DC%2BD38vjtVKnsA%3D%3D 12186679 10.1080/1025389021000010503
251. M Weinstock 2007 Gender differences in the effects of prenatal stress on brain development and behaviour Neurochem Res 32 1730 1740 1:CAS:528: DC%2BD2sXhtVGmsLzE 17406975 10.1007/s11064-007-9339-4 (Pubitemid 47428852)
252. M Weinstock 2008 The long-term behavioural consequences of prenatal stress Neurosci Biobehav Rev 32 1073 1086 1:CAS:528:DC%2BD1cXotlCgs7g%3D 18423592 10.1016/j.neubiorev.2008.03.002
253. JJ Wetzels SP Kremers PD Vitoria H de Vries 2003 The alcohol-tobacco relationship: a prospective study among adolescents in six European countries Addiction 98 1755 1763 1:STN:280:DC%2BD3srmsVagtw%3D%3D 14651508 10.1111/j.1360-0443.2003.00553.x (Pubitemid 38030784)
254. RH Yolken H Karlsson F Yee NL Johnston-Wilson EF Torrey 2000 Endogenous retroviruses and schizophrenia Brain Res Brain Res Rev 31 193 199 1:CAS:528:DC%2BD3cXhsleqtr4%3D 10719148 10.1016/S0165-0173(99)00037-5 (Pubitemid 30136176)
255. B Zimmerberg AM Shartrand 1992 Temperature-dependent effects of maternal separation on growth, activity, and amphetamine sensitivity in the rat Dev Psychobiol 25 213 226 1:STN:280:DyaK38zhs1ehtw%3D%3D 1618372 10.1002/dev.420250306
256. L Zuckerman M Rehavi R Nachman I Weiner 2003 Immune activation during pregnancy in rats leads to a postpubertal emergence of disrupted latent inhibition, dopaminergic hyperfunction, and altered limbic morphology in the offspring: a novel neurodevelopmental model of schizophrenia Neuropsychopharmacology 28 1778 1789 1:CAS:528:DC%2BD3sXnsVyisbs%3D 12865897 10.1038/sj.npp.1300248 (Pubitemid 41070843)
257. AR Zuena J Mairesse P Casolini C Cinque GS Alema S Morley-Fletcher V Chiodi LG Spagnoli R Gradini A Catalani F Nicoletti S Maccari 2008 Prenatal restraint stress generates two distinct behavioral and neurochemical profiles in male and female rats PLoS One 3 e2170 18478112 10.1371/journal.pone.0002170 1:CAS:528:DC%2BD1cXmvVSlu7g%3D