Effect and safety of granulocyte-monocyte adsorption apheresis for patients with ulcerative colitis positive for cytomegalovirus in comparison with immunosuppressants

Digestion

Volumn 84, Issue 1, 2011, Pages 3-9

  Yoshino, Takuya ^a   Nakase, Hiroshi ^a   Matsuura, Minoru ^a   Matsumura, Kayoko ^a   Honzawa, Yusuke ^a   Fukuchi, Takumi ^b   Watanabe, Kenji ^c   Murano, Mitsuyuki ^d   Tsujikawa, Tomoyuki ^e   Fukunaga, Ken ^f   Matsumoto, Takayuki ^f   Chiba, Tsutomu ^a  

^a KYOTO UNIVERSITY   (Japan)

^b SAISEIKAI NAKATSU HOSPITAL   (Japan)

^c OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d OSAKA MEDICAL COLLEGE   (Japan)

^e SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^f HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

Cytomegalovirus; Ganciclovir; Granulocyte monocyte adsorption apheresis; Ulcerative colitis

Indexed keywords

AZATHIOPRINE; GANCICLOVIR; STEROID; TACROLIMUS; VIRUS ANTIGEN; VIRUS DNA;

ADULT; AGED; ANTIGENICITY; ANTIVIRAL THERAPY; APHERESIS; CLINICAL ASSESSMENT; CLINICAL EVALUATION; COLITIS; COMPARATIVE STUDY; CONTROLLED STUDY; CYTAPHERESIS; CYTOMEGALOVIRUS INFECTION; DISEASE COURSE; DRUG WITHDRAWAL; ENDOSCOPY; GRANULOCYTE MONOCYTE ADSORPTION APHERESIS; HISTOLOGY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOSUPPRESSIVE TREATMENT; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; PANCOLITIS; PRIORITY JOURNAL; PROCTITIS; REAL TIME POLYMERASE CHAIN REACTION; RELAPSE; REMISSION; RETROSPECTIVE STUDY; REVIEW; SAFETY; SURVIVAL; THERAPY EFFECT; TREATMENT DURATION; TREATMENT INDICATION; ULCERATIVE COLITIS; VIRUS DETECTION; VIRUS REACTIVATION;

ADOLESCENT; ADSORPTION; ADULT; AGED; AGED, 80 AND OVER; ANTIVIRAL AGENTS; COLECTOMY; COLITIS, ULCERATIVE; COMBINED MODALITY THERAPY; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; GANCICLOVIR; GRANULOCYTES; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LEUKAPHERESIS; MIDDLE AGED; MONOCYTES; POLYMERASE CHAIN REACTION; RECURRENCE; REMISSION INDUCTION; RETROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 79751523954     PISSN: 00122823     EISSN: 14219867     Source Type: Journal    
DOI: 10.1159/000321911     Document Type: Review

References (18)

1. Nakase H, Matsumura K, Yoshino T, et al: Systematic review: cytomegalovirus infection in inflammatory bowel disease. J Gastroenterol 2008; 43: 735-740.
2. Nakase H, Yoshino T, Ueno S, et al: Importance of early detection of cytomegalovirus infection in refractory inflammatory bowel disease. Inflamm Bowel Dis 2007; 13: 364. (Pubitemid 46465919) (Pubitemid 46465919)
3. Yoshino T, Nakase H, Ueno S, et al: Usefulness of quantitative real-time PCR assay for early detection of cytomegalovirus infection in patients with ulcerative colitis refractory to immunosuppressive therapies. Inflamm Bowel Dis 2007; 13: 1516-1521.
4. Kou T, Nakase H, Tamaki H, et al: Cytomegalovirus infection in patients with ulcerative colitis diagnosed by quantitative real-time PCR analysis. Dig Dis Sci 2006; 51: 1052-1055. (Pubitemid 44127052) (Pubitemid 44127052)
5. Domènech E, Roser V, Ojanguren I, et al: Cytomegalovirus infection in ulcerative colitis: a prospective, comparative study on prevalence and diagnostic strategy. Inflamm Bowel Dis 2008; 14: 1373-1379.
6. Onyeagocha C, Hossain MS, Kumar A, et al: Latent cytomegalovirus infection exacerbates experimental colitis. Am J Pathol 2009; 175: 2034-2042.
7. Shimoyama T, Sawada K, Hiwatashi N, et al: Safety and efficacy of granulocyte and monocyte adsorption apheresis in patients with active ulcerative colitis: a multicenter study. J Clin Apher 2001; 16: 1-9.
8. Simon CO, Seckert CK, Dreis D, et al: Role of tumor necrosis factor-α in murine cytomegalovirus transcriptional reactivation in latently infected lungs. J Virol 2005; 79: 326-340. (Pubitemid 39648387) (Pubitemid 39648387)
9. Chan G, Bivins-Smith ER, Smith MS, et al: Transcriptome analysis reveals human cytomegalovirus reprograms monocyte differentiation toward an M1 macrophage. J Immunol 2008; 181: 698-711.
10. Matts SG: The value of rectal biopsy in the diagnosis of ulcerative colitis. Q J Med 1961; 30: 393-407.
11. Cottone M, Pietrosi G, Martorana G, et al: Prevalence of cytomegalovirus infection in severe refractory ulcerative colitis and Crohn's colitis. Am J Gastroenterol 2001; 96: 773-775. (Pubitemid 32240729) (Pubitemid 32240729)
12. Papadakis KA, Tung JK, Binder SW, et al: Outcome of cytomegalovirus infection in patients with inflammatory bowel disease. Am J Gastroenterol 2001; 96: 2137-2142. (Pubitemid 32660910) (Pubitemid 32660910)
13. Hommes DW, Sterringa G, van Deventer SJ, et al: The pathogenicity of cytomegalovirus in inflammatory bowel disease: a systematic review and evidence-based recommendations for future research. Inflamm Bowel Dis 2004; 10: 245-250. (Pubitemid 38618254) (Pubitemid 38618254)
14. Nakase H, Yoshino T, Matsumura K, et al: Positive finding of colonic PCR for CMV DNA is not false positive but warning for treating patients with UC refractory to immunosuppressive therapies. Inflamm Bowel Dis (in press).
15. Rubin RH: Impact of cytomegalovirus infection on organ transplant recipients. Rev Infect Dis 1990; 12(suppl 7):S754-S766. (Pubitemid 20311817) (Pubitemid 20311817)
16. Nakase H, Chiba T: TNF-α is an important pathogenic factor contributing to reactivation of cytomegalovirus in inflamed mucosa of colon in patients with ulcerative colitis: lesson from clinical experience. Inflamm Bowel Dis 2010; 16: 550-551.
17. Criscuoli V, Mocciaro F, Orlando A, et al: Cytomegalovirus disappearance after treatment for refractory ulcerative colitis in two patients treated with infliximab and one patient with leukapheresis. Inflamm Bowel Dis 2009; 15: 810-811.
18. D'Ovidio V, Vernia P, Gentile G, et al: Cytomegalovirus infection in inflammatory bowel disease patients undergoing anti-TNF-α therapy. J Clin Virol 2008; 43: 180-183.