Size, concentration and incubation time dependence of gold nanoparticle uptake into pancreas cancer cells and itsfuture application to X-ray drug delivery system

Journal of Radiation Research

Volumn 52, Issue 1, 2011, Pages 103-109

  Trono, Jade Dungao ^a   Mizuno, Kazue ^a   Yusa, Noritaka ^b   Matsukawa, Takehisa ^c   Yokoyama, Kazuhito ^c   Uesaka, Mitsuru ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOHOKU UNIVERSITY   (Japan)

^c JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Gold nanoparticles; In vitro uptake; Pancreas cancer cells; X ray drug delivery system

Indexed keywords

ABSORPTION SPECTROSCOPY; ATOMIC ABSORPTION SPECTROMETRY; CELLS; CONTROLLED DRUG DELIVERY; CYTOLOGY; DIAGNOSIS; DISEASES; FIBER OPTIC SENSORS; MEDICAL IMAGING; METAL NANOPARTICLES; TARGETED DRUG DELIVERY; TEMPERATURE DISTRIBUTION; ULTRAVIOLET VISIBLE SPECTROSCOPY;

CANCER CELLS; DRUG-DELIVERY SYSTEMS; GOLD NANOPARTICLE; GOLD NANOPARTICLES; IN-VITRO; IN-VITRO UPTAKE; INCUBATION TIME; PANCREAS CANCER; PANCREAS CANCER CELL; X-RAY DRUG DELIVERY SYSTEM;

GOLD NANOPARTICLES;

EID: 79751485223     PISSN: 04493060     EISSN: 13499157     Source Type: Journal    
DOI: 10.1269/jrr.10068     Document Type: Article

References (20)

1. Willett CG, et al (2005) Locally Advanced Pancreatic Cancer. J Clin Oncol 23(20): 4538-4544.
2. Urschel HC, Kresl JJ and Luketich JD (2007) Treating tumors that move with respiration. Springer.
3. Wang J, et al (2009) Intraoperative ultrasound-guided iodine-125 seed implantation for unresectable pancreatic carcinoma. J Exp Clin Cancer Res 28(1): 88.
4. XCOM [homepage on the internet]. NIST Available from: http://physics.nist.gov/PhysRefData/Xcom/html/xcom1.html
5. Sinha R, et al (2006) Nanotechnology in cancer therapeutics: bioconjugated nanoparticles for drug delivery. Mol Cancer Ther 5(8): 1909-1917.
6. January 2009 Aurovist: Product Information and Instructions [homepage on the internet]. Available from: http://www.nanoprobes.com/Inf1102.html
7. Chang M-Y, et al (2008) Increased apoptotic potential and dose-enhancing effect of gold nanoparticles in combination with single-dose clinical electron beams on tumor-bearing mice. Cancer Sci 99(7): 1479-1484.
8. Chithrani BD, Ghazani AA and Chan WCW (2006) Determining the Size and Shape Dependence of Gold Nanoparticle Uptake into Mammalian Cells. Nano Letters 6(4): 662-668.
9. Hainfeld JF, et al (2006) Gold nanoparticles: a new X-ray contrast agent. Br J Radiol 79(939): 248-253.
10. Hainfeld JF, et al (2008) Radiotherapy enhancement with gold nanoparticles. J Pharm Pharmacol 60(8): 977-985.
11. Yusa N, et al (2009) Numerical evaluation of the effectiveness of colloidal gold as a contrast agent. Radiol Phys Tech 2(1): 33-39.
12. Shirato H, et al (2003) Feasibility of insertion/implantation of 2.0-mm-diameter gold internal fiducial markers for precise setup and real-time tumor tracking in radiotherapy. Int J Radiat Oncol Biol Phys 56(1): 240-247.
13. M. Uesaka, et al (2007) Pinpoint KeV/MeV x-ray sources for x-ray drug delivery system. Particle Accelerator Conference, 2007 PAC IEEE: 2793-2795.
14. Hashimoto E, et al (2009) Medical and Nuclear Applications of Micro Electron Beam Linear Accelerator X-ray Sources.Int J Automation Technology 3(5): 10.
15. Uesaka M, et al (2009) Application of monochromatic keV X-ray source to X-ray drug delivery system. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment 608(1, Supplement 1): S47-S50.
16. Erika Porcel SL, et al (2010) Platinum nanoparticles: a promising material for future cancer therapy? Nanotechnology 21(8): 085103.
17. Khan JA, et al (2007) Molecular Effects of Uptake of Gold Nanoparticles in HeLa Cells. Chem Bio Chem 8(11): 1237-1240.
18. BBInternational [homepage on the internet]. Available from: http://www.britishbiocell.co.uk/products/goldadvantage.asp?navid=2
19. Martin de Llano JJ, et al (2000) Electrothermal Atomic Absorption Spectrometric Diagnosis of Familial Hypercholesterolemia. Analytical Chemistry 72(11): 2406-2413.
20. Gao H, Shi W and Freund LB (2005) Mechanics of receptor-mediated endocytosis. Proc Natl Acad Sci USA 102(27): 9469-9474.