An investigation into the origin of the dramatically reduced reactivity of peptide-prolyl-thioesters in native chemical ligation

Chemical Communications

Volumn 47, Issue 8, 2011, Pages 2342-2344

  Pollock, Samuel B ^a   Kent, Stephen B H ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CARBONYL DERIVATIVE; NITROGEN; PROLINE; THIOXYL DERIVATIVE;

ARTICLE; ATOM; CARBOHYDRATE ANALYSIS; LIGATION;

EID: 79751472553     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c0cc04120c     Document Type: Article

References (9)

1. P. E. Dawson, T. W. Muir, I. Clark-Lewis, S. B. H. Kent: Science, 1994 266:776-779.
2. T. M. Hackeng, J. H. Griffin, P. E. Dawson: Proc. Natl. Acad. Sci. U. S. A., 1999 96:10068-10073.
3. Z. Tan, S. Shang, S. J. Danishefsky: Angew. Chem., 2010 122:1-5.
4. E. C. B. Johnson, S. B. H. Kent: J. Am. Chem. Soc., 2006 128:6640-6646.
5. H. Rohde, O. J. Seitz: Biopolymers (Pept. Sci.), 2010 16:88.
6. M. P. Hinderaker, R. T. Raines: Protein Sci., 2003 12:1188-1194.
7. J. A. Hodges, R. T. Raines: Org. Lett., 2006 8:4695-4697.
8. A. Choudhary, K. J. Kamer, M. W. Powner, J. D. Sutherland, R. T. Raines: ACS Chem. Biol., 2010 5:655-657.
9. G. J. Bartlett, A. Choudhary, R. T. Raines, D. N. Woolfson: Nat. Chem. Biol., 2010 6:615-620.