Amplification and overexpression of vinculin are associated with increased tumour cell proliferation and progression in advanced prostate cancer

Journal of Pathology

Volumn 223, Issue 4, 2011, Pages 543-552

  Ruiz, Christian ^a   Holz, David R ^b   Oeggerli, Martin ^a   Schneider, Sandra ^a   Gonzales, Irma M ^b   Kiefer, Jeffrey M ^b   Zellweger, Tobias ^c   Bachmann, Alexander ^d   Koivisto, Pasi A ^e   Helin, Heikki J ^f   Mousses, Spyro ^b   Barrett, Michael T ^b   Azorsa, David O ^b   Bubendorf, Lukas ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^c Division of Urology   (Switzerland)

^d UNIVERSITY HOSPITAL BASEL   (Switzerland)

^e Seinäjoki and Vaasa Central Hospitals   (Finland)

^f HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

10q22; array CGH; prostate cancer; tissue microarray; vinculin

Indexed keywords

DISCS LARGE HOMOLOGUE 5 PROTEIN; KI 67 ANTIGEN; PROTEIN; UNCLASSIFIED DRUG; VINCULIN;

ADVANCED CANCER; AMPLICON; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CASTRATION; CELL PROLIFERATION; CHROMOSOME 10Q; COMPARATIVE GENOMIC HYBRIDIZATION; GENE AMPLIFICATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATE CARCINOMA; PROSTATE HYPERTROPHY; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROTEIN EXPRESSION; RNA INTERFERENCE; TISSUE MICROARRAY;

CELL PROLIFERATION; CHROMOSOMES, HUMAN, PAIR 10; COMPARATIVE GENOMIC HYBRIDIZATION; DISEASE PROGRESSION; GENE AMPLIFICATION; GENETIC ASSOCIATION STUDIES; HUMANS; MALE; NEOPLASM PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROSTATIC HYPERPLASIA; PROSTATIC INTRAEPITHELIAL NEOPLASIA; PROSTATIC NEOPLASMS; RNA, NEOPLASM; RNA, SMALL INTERFERING; VINCULIN;

EID: 79551714077     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2828     Document Type: Article

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