Balamuthia mandrillaris brain abscess successfully treated with complete surgical excision and prolonged combination antimicrobial therapy: Case report

Journal of Neurosurgery

Volumn 114, Issue 2, 2011, Pages 458-462

  Doyle, Joseph S ^a   Campbell, Emer ^a   Fuller, Andrew ^a   Spelman, Denis W ^a   Cameron, Rhoda ^a   Malham, Gregory ^a   Gin, Douglas ^a   Lewin, Sharon R ^a,b,c  

^a ALFRED HOSPITAL   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c BURNET INSTITUTE   (Australia)

Author keywords

Balamuthia mandrillaris; Brain abscess; Free living amoeba

Indexed keywords

AMPHOTERICIN B LIPID COMPLEX; AZITHROMYCIN; CEFTRIAXONE; CORTICOSTEROID; FLUCYTOSINE; ITRACONAZOLE; METRONIDAZOLE; PENICILLIN G; PENTAMIDINE; PHENYTOIN; PREDNISOLONE; SULFADIAZINE;

AGED; ARTICLE; BACTERIAL STRAIN; BALAMUTHIA INFECTION; BRAIN ABSCESS; CASE REPORT; CELL INFILTRATION; DISEASE COURSE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; ERYTHEMA; FEMALE; HUMAN; HUMAN TISSUE; HYPOTENSION; KIDNEY DISEASE; PRIORITY JOURNAL; SIDE EFFECT; SKIN BIOPSY; TONIC CLONIC SEIZURE; TREATMENT OUTCOME; TROPHOZOITE;

AGED, 80 AND OVER; AMEBIASIS; AMOEBIDA; ANTI-INFECTIVE AGENTS; BRAIN ABSCESS; CENTRAL NERVOUS SYSTEM PROTOZOAL INFECTIONS; FEMALE; FRONTAL LOBE; HUMANS;

EID: 79551713882     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2010.10.JNS10677     Document Type: Article

References (18)

1. Deetz TR, Sawyer MH, Billman G, Schuster FL, Visvesvara GS: Successful treatment of Balamuthia amoebic encephalitis: presentation of 2 cases. Clin Infect Dis 37:1304-1312, 2003 (Pubitemid 37433625)
2. Gelman BB, Rauf SJ, Nader R, Popov V, Borkowski J, Chaljub G, et al: Amoebic encephalitis due to Sappinia diploidea. JAMA 285:2450-2451, 2001 (Pubitemid 32433836)
3. Jung S, Schelper RL, Visvesvara GS, Chang HT: Balamuthia mandrillaris meningoencephalitis in an immunocompetent patient: an unusual clinical course and a favorable outcome. Arch Pathol Lab Med 128:466-468, 2004 (Pubitemid 38451140)
4. Kansagra AP, Menon JP, Yarbrough CK, Urbaniak K, Waters JD, Borys E, et al: Balamuthia mandrillaris meningoencephalitis in an immunocompromised patient. Case report. J Neurosurg 111:301-305, 2009
5. Marciano-Cabral F: Free-living amoebae as agents of human infection. J Infect Dis 199:1104-1106, 2009
6. Marciano-Cabral F, Cabral G: Acanthamoeba spp. as agents of disease in humans. Clin Microbiol Rev 16:273-307, 2003 (Pubitemid 36519813)
7. Matin A, Siddiqui R, Jayasekera S, Khan NA: Increasing importance of Balamuthia mandrillaris. Clin Microbiol Rev 21:435-448, 2008
8. Pritzker AS, Kim BK, Agrawal D, Southern PM Jr, Pandya AG: Fatal granulomatous amebic encephalitis caused by Balamuthia mandrillaris presenting as a skin lesion. J Am Acad Dermatol 50 (2 Suppl):S38-S41, 2004 (Pubitemid 38167046)
9. Qvarnstrom Y, da Silva AJ, Schuster FL, Gelman BB, Visvesvara GS: Molecular confirmation of Sappinia pedata as a causative agent of amoebic encephalitis. J Infect Dis 199:1139-1142, 2009
10. Reed RP, Cooke-Yarborough CM, Jaquiery AL, Grimwood K, Kemp AS, Su JC, et al: Fatal granulomatous amoebic encephalitis caused by Balamuthia mandrillaris. Med J Aust 167:82-84, 1997 (Pubitemid 27359128)
11. Schuster FL, Guglielmo BJ, Visvesvara GS: In-vitro activity of miltefosine and voriconazole on clinical isolates of free-living amebas: Balamuthia mandrillaris, Acanthamoeba spp., and Naegleria fowleri. J Eukaryot Microbiol 53:121-126, 2006 (Pubitemid 43357017)
12. Schuster FL, Visvesvara GS: Axenic growth and drug sensitivity studies of Balamuthia mandrillaris, an agent of amebic meningoencephalitis in humans and other animals. J Clin Microbiol 34:385-388, 1996 (Pubitemid 26035116)
13. Schuster FL, Yagi S, Gavali S, Michelson D, Raghavan R, Blomquist I, et al: Under the radar: Balamuthia amebic encephalitis. Clin Infect Dis 48:879-887, 2009
14. Schuster FL, Yagi S, Wilkins PP, Gavali S, Visvesvara GS, Glaser CA: Balamuthia mandrillaris, agent of amebic encephalitis: detection of serum antibodies and antigenic similarity of isolates by enzyme immunoassay. J Eukaryot Microbiol 55:313-320, 2008 (Pubitemid 351952014)
15. Siddiqui R, Khan NA: Balamuthia amoebic encephalitis: an emerging disease with fatal consequences. Microb Pathog 44:89-97, 2008 (Pubitemid 350297678)
16. Visvesvara GS, Moura H, Schuster FL: Pathogenic and opportunistic free-living amoebae: Acanthamoeba spp., Balamuthia mandrillaris, Naegleria fowleri, and Sappinia diploidea. FEMS Immunol Med Microbiol 50:1-26, 2007 (Pubitemid 46763469)
17. Yagi S, Booton GC, Visvesvara GS, Schuster FL: Detection of Balamuthia mitochondrial 16S rRNA gene DNA in clinical specimens by PCR. J Clin Microbiol 43:3192-3197, 2005 (Pubitemid 40981322)
18. Yagi S, Schuster FL, Visvesvara GS: Demonstration of Balamuthia and Acanthamoeba mitochondrial DNA in sectioned archival brain and other tissues by the polymerase chain reaction. Parasitol Res 102:491-497, 2008