메뉴 건너뛰기




Volumn 40, Issue 12, 2010, Pages 659-664

Simvastatin, sildenafil and their combination in monocrotaline induced pulmonary arterial hypertension

Author keywords

Pulmonary circulation; Pulmonary hypertension; Sildenafil; Simvastatin

Indexed keywords

CELL ANTIGEN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MONOCROTALINE; SILDENAFIL; SIMVASTATIN; SODIUM CHLORIDE;

EID: 79551699842     PISSN: 17385520     EISSN: 17385555     Source Type: Journal    
DOI: 10.4070/kcj.2010.40.12.659     Document Type: Article
Times cited : (12)

References (29)
  • 1
    • 2942541475 scopus 로고    scopus 로고
    • Cellular and molecular pathobiology of pulmonary arterial hypertension
    • Humbert M, Morrell NW, Archer SL, et al. Cellular and molecular pathobiology of pulmonary arterial hypertension. J Am Coll Cardiol 2004;43(12 Suppl S):13S-24S.
    • (2004) J Am Coll Cardiol , vol.43 , Issue.12 SUPPL. S
    • Humbert, M.1    Morrell, N.W.2    Archer, S.L.3
  • 2
    • 33645104291 scopus 로고    scopus 로고
    • Pulmonary arterial hypertension: New insights and new hope
    • Martin KB, Klinger JR, Rounds SI. Pulmonary arterial hypertension: new insights and new hope. Respirology 2006;11:6-17.
    • (2006) Respirology , vol.11 , pp. 6-17
    • Martin, K.B.1    Klinger, J.R.2    Rounds, S.I.3
  • 3
    • 34447318895 scopus 로고    scopus 로고
    • Clinical characteristics and prognostic factors of patients with severe pulmonary hypertension
    • Lee WS, Kim KH, Jeong DH, et al. Clinical characteristics and prognostic factors of patients with severe pulmonary hypertension. Korean Circ J 2007;37:265-70.
    • (2007) Korean Circ J , vol.37 , pp. 265-270
    • Lee, W.S.1    Kim, K.H.2    Jeong, D.H.3
  • 4
    • 24144484100 scopus 로고    scopus 로고
    • Current treatment strategies for pulmonary arterial hypertension
    • DOI 10.1111/j.1365-2796.2005.01542.x
    • Lee SH, Rubin LJ. Current treatment strategies for pulmonary arterial hypertension. J Intern Med 2005;258:199-215. (Pubitemid 41243051)
    • (2005) Journal of Internal Medicine , vol.258 , Issue.3 , pp. 199-215
    • Lee, S.H.1    Rubin, L.J.2
  • 5
    • 4644290657 scopus 로고    scopus 로고
    • Treatment of pulmonary arterial hypertension
    • Humbert M, Sitbon O, Simmoneau G. Treatment of pulmonary arterial hypertension. N Engl J Med 2004;351:1425-36.
    • (2004) N Engl J Med , vol.351 , pp. 1425-1436
    • Humbert, M.1    Sitbon, O.2    Simmoneau, G.3
  • 8
    • 0041859249 scopus 로고    scopus 로고
    • Attenuation of chronic hypoxic pulmonary hypertension by simvastatin
    • Girgis RE, Li D, Zhan X, et al. Attenuation of chronic hypoxic pulmonary hypertension by simvastatin. Am J Physiol Heart Circ Physiol 2003;285:H938-45.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285
    • Girgis, R.E.1    Li, D.2    Zhan, X.3
  • 11
    • 0037741441 scopus 로고    scopus 로고
    • Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension
    • DOI 10.1161/01.CIR.0000074226.20466.B1
    • Sebkhi A, Strange JW, Phillips SC, Wharton J, Wilkins MR. Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension. Circulation 2003;107:3230-5. (Pubitemid 36793096)
    • (2003) Circulation , vol.107 , Issue.25 , pp. 3230-3235
    • Sebkhi, A.1    Strange, J.W.2    Phillips, S.C.3    Wharton, J.4    Wilkins, M.R.5
  • 13
    • 0036663330 scopus 로고    scopus 로고
    • Chronic oral sildenafil therapy in severe pulmonary artery hypertension
    • Kothari SS, Duggal B. Chronic oral sildenafil therapy in severe pulmonary artery hypertension. Indian Heart J 2002;54-404-9. (Pubitemid 35447129)
    • (2002) Indian Heart Journal , vol.54 , Issue.4 , pp. 404-409
    • Kothari, S.S.1    Duggal, B.2
  • 14
    • 1842530387 scopus 로고    scopus 로고
    • Clinical efficacy of sildenafil in primary pulmonary hypertension: A randomized, placebo-controlled, double-blind, crossover study
    • DOI 10.1016/j.jacc.2003.10.056, PII S0735109704001056
    • Sastry BK, Narasimhan C, Reddy NK, Raju BS. Clinical efficacy of sildenafil in primary pulmonary hypertension: a randomized, placebo-controlled, double-blind, crossover study. J Am Coll Cardiol 2004;43:1149-53. (Pubitemid 38452588)
    • (2004) Journal of the American College of Cardiology , vol.43 , Issue.7 , pp. 1149-1153
    • Sastry, B.K.S.1    Narasimhan, C.2    Reddy, N.K.3    Raju, B.S.4
  • 17
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Takemoto M, Liao JK. Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 2001;21:1712-9. (Pubitemid 34219772)
    • (2001) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.21 , Issue.11 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 18
    • 0031451344 scopus 로고    scopus 로고
    • Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase
    • DOI 10.1074/jbc.272.50.31725
    • Laufs U, Fata VL, Liao JK. Inhibition of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase blocks hypoxia-mediated down-regulation of endothelial nitric oxide synthase. J Biol Chem 1997;272:31725-9. (Pubitemid 28013321)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.50 , pp. 31725-31729
    • Laufs, U.1    La, F.V.2    Liao, J.K.3
  • 19
    • 33748778726 scopus 로고    scopus 로고
    • Effects of simvastatin alone or combined with ramipril on nitric oxide bioactivity and inflammation markers in hypercholesterolemic patients
    • Son JW, Koh KK, You SM, et al. Effects of simvastatin alone or combined with ramipril on nitric oxide bioactivity and inflammation markers in hypercholesterolemic patients. Korean Circ J 2003;33:1053-9.
    • (2003) Korean Circ J , vol.33 , pp. 1053-1059
    • Son, J.W.1    Koh, K.K.2    You, S.M.3
  • 21
    • 48349129130 scopus 로고    scopus 로고
    • The protective effect of simvastatin on monocrotaline-induced pulmonary hypertension in rats
    • Kim MY, Kim YK, Jung YW, Kim WT, Kwon TH, Lee DS. The protective effect of simvastatin on monocrotaline-induced pulmonary hypertension in rats. Korean Circ J 2008;38:313-9.
    • (2008) Korean Circ J , vol.38 , pp. 313-319
    • Kim, M.Y.1    Kim, Y.K.2    Jung, Y.W.3    Kim, W.T.4    Kwon, T.H.5    Lee, D.S.6
  • 22
    • 19044366349 scopus 로고    scopus 로고
    • Simvastatin treatment of pulmonary hypertension: An observational case series
    • DOI 10.1378/chest.127.4.1446
    • Kao PN. Simvastatin treatment of pulmonary hypertension: an observational case series. Chest 2005;127:1446-52. (Pubitemid 46224314)
    • (2005) Chest , vol.127 , Issue.4 , pp. 1446-1452
    • Kao, P.N.1
  • 24
    • 34250870730 scopus 로고    scopus 로고
    • Medical therapy for pulmonary arterial hypertension: Updated ACCP evidence-based clinical practice guidelines
    • DOI 10.1378/chest.06-2674
    • Badesch DB, Abman SH, Simonneau G, Rubin LJ, McLaughlin VV. Medical therapy for pulmonary arterial hypertension: updated ACCP evidence-based clinical practice guidelines. Chest 2007;131:1917-28. (Pubitemid 46981654)
    • (2007) Chest , vol.131 , Issue.6 , pp. 1917-1928
    • Badesch, D.B.1    Abman, S.H.2    Simonneau, G.3    Rubin, L.J.4    McLaughlin, V.V.5
  • 25
    • 65349171770 scopus 로고    scopus 로고
    • 3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension
    • Satoh M, Satoh A. 3-Hydroxy-3-methylglutaryl (HMG)-COA reductase inhibitors and phosphodiesterase type V inhibitors attenuate right ventricular pressure and remodeling in a rat model of pulmonary hypertension. J Pharm Pharm Sci 2009;11:118s-30s.
    • (2009) J Pharm Pharm Sci , vol.11
    • Satoh, M.1    Satoh, A.2
  • 26
    • 34848838260 scopus 로고    scopus 로고
    • Oral sildenafil prevents and reverses the development of pulmonary hypertension in monocrotaline-treated rats
    • DOI 10.1510/icvts.2006.147033
    • Liu H, Liu ZY, Guan Q. Oral sildenafil prevents and reverses the development of pulmonary hypertension in monocrotaline-treated rats. Interact Cardiovasc Thorac Surg 2007;6:608-13. (Pubitemid 47598511)
    • (2007) Interactive Cardiovascular and Thoracic Surgery , vol.6 , Issue.5 , pp. 608-613
    • Liu, H.1    Liu, Z.-Y.2    Guan, Q.3
  • 27
    • 70349649065 scopus 로고    scopus 로고
    • Simvastatin and sildenafil combine to attenuate pulmonary hypertension
    • Zhao L, Sebkhi A, Ali O, et al. Simvastatin and sildenafil combine to attenuate pulmonary hypertension. Eur Respir J 2009;34:948-57.
    • (2009) Eur Respir J , vol.34 , pp. 948-957
    • Zhao, L.1    Sebkhi, A.2    Ali, O.3
  • 28
    • 77955413732 scopus 로고    scopus 로고
    • Combination of sildenafil and simvastatin ameliorates monocrotaline-induced pulmonary hypertension in rats
    • Kuang T, Wang J, Pang B, et al. Combination of sildenafil and simvastatin ameliorates monocrotaline-induced pulmonary hypertension in rats. Pulm Pharmacol Ther 2010;23:456-64.
    • (2010) Pulm Pharmacol Ther , vol.23 , pp. 456-464
    • Kuang, T.1    Wang, J.2    Pang, B.3
  • 29
    • 35348869290 scopus 로고    scopus 로고
    • Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: The rapamcyin-atorvastatin-simvastatin study
    • McMurtry MS, Bonnet S, Michelakis ED, Bonnet S, Haromy A, Archer SL. Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study. Am J Physiol Lung Cell Mol Physiol 2007;293:L933-40.
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293
    • McMurtry, M.S.1    Bonnet, S.2    Michelakis, E.D.3    Bonnet, S.4    Haromy, A.5    Archer, S.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.