Implications of the CHA2DS2-VASc and HAS-BLED scores for thromboprophylaxis in atrial fibrillation

American Journal of Medicine

Volumn 124, Issue 2, 2011, Pages 111-114

  Lip, Gregory Y H ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Atrial fibrillation; Bleeding; Risk stratification scheme; Stroke

Indexed keywords

ANTICOAGULANT AGENT;

AGE DISTRIBUTION; ANTICOAGULANT THERAPY; ARTICLE; BLEEDING; CHA2DS2 VASC SCORE; CLINICAL ASSESSMENT TOOL; CONGESTIVE HEART FAILURE; DIABETES MELLITUS; HAS BLED SCORE; HEART ATRIUM FIBRILLATION; HUMAN; HYPERTENSION; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SCORING SYSTEM; SEX DIFFERENCE; STROKE; THROMBOSIS PREVENTION; VASCULAR DISEASE;

EID: 79551683853     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjmed.2010.05.007     Document Type: Note

References (18)

1. M. Hughes, and G.Y. Lip Stroke and thromboembolism in atrial fibrillation: a systematic review of stroke risk factors, risk stratification schema and cost effectiveness data Thromb Haemost 99 2008 295 304
2. B.F. Gage, A.D. Waterman, W. Shannon, M. Boechler, M.W. Rich, and M.J. Radford Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation JAMA 285 2001 2864 2870
3. G.Y.H. Lip, and J. Halperin Improving stroke risk stratification in atrial fibrillation Am J Med 123 2010 484 488
4. Y. Wan, C. Heneghan, and R. Perera Anticoagulation control and prediction of adverse events in patients with atrial fibrillation: a systematic review Circ Cardiovasc Qual Outcomes 1 2008 84 91
5. C.L. Morgan, P. McEwan, A. Tukiendorf, P.A. Robinson, A. Clemens, and J.M. Plumb Warfarin treatment in patients with atrial fibrillation: observing outcomes associated with varying levels of INR control Thromb Res 124 2009 37 41
6. J. Mant, F.D. Hobbs, and K. Fletcher Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trial Lancet 370 2007 493 503 (Pubitemid 47212371)
7. G. Palareti, and B. Cosmi Bleeding with anticoagulation therapywho is at risk, and how best to identify such patients Thromb Haemost 102 2009 268 278
8. T.I. Shireman, P.A. Howard, T.F. Kresowik, and E.F. Ellerbeck Combined anticoagulant-antiplatelet use and major bleeding events in elderly atrial fibrillation patients Stroke 35 2004 2362 2367
9. B.F. Gage, Y. Yan, and P.E. Milligan Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF) Am Heart J 151 2006 713 719
10. R.J. Beyth, L.M. Quinn, and C.S. Landefeld Prospective evaluation of an index for predicting the risk of major bleeding in outpatients treated with warfarin Am J Med 105 1998 91 99
11. P.M. Kuijer, B.A. Hutten, M.H. Prins, and H.R. Buller Prediction of the risk of bleeding during anticoagulant treatment for venous thromboembolism Arch Intern Med 159 1999 457 460
12. R. Pisters, D.A. Lane, R. Nieuwlaat, C.B. de Vos, H.J. Crijns, and G.Y. Lip A novel user-friendly score (HAS-BLED) to assess one-year risk of major bleeding in atrial fibrillation patients: the Euro Heart Survey Chest 2010;Mar 18 [Epub ahead of print]
13. G.Y.H. Lip Anticoagulation therapy and the risk of stroke in patients with Atrial Fibrillation at 'moderate risk' [CHADS2 score = 1]: simplifying stroke risk assessment and thromboprophylaxis in real-life clinical practice Thromb Haemost 4 103 2010 683 685
14. H. Sato, K. Ishikawa, and A. Kitabatake Low-dose aspirin for prevention of stroke in low-risk patients with atrial fibrillation: Japan Atrial Fibrillation Stroke Trial Stroke 37 2006 447 451
15. R.G. Hart, L.A. Pearce, and M.I. Aguilar Meta-analysis: antithrombotic therapy to prevent stroke in patients who have nonvalvular atrial fibrillation Ann Intern Med 146 2007 857 867
16. Stroke Prevention in Atrial Fibrillation investigators A differential effect of aspirin in prevention of stroke on atrial fibrillation J Stroke Cerebrovasc Dis 3 1993 181 188
17. G.Y. Lip, R. Nieuwlaat, R. Pisters, D.A. Lane, and H.J. Crijns Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the Euro Heart Survey on atrial fibrillation Chest 137 2010 263 272
18. S.J. Connolly, M.D. Ezekowitz, S. Yusuf RE-LY Steering Committee and Investigators Dabigatran versus warfarin in patients with atrial fibrillation N Engl J Med 361 2009 1139 1151