Detection of prion infection in variant Creutzfeldt-Jakob disease: A blood-based assay

The Lancet

Volumn 377, Issue 9764, 2011, Pages 487-493

  Edgeworth, Julie Ann ^a   Farmer, Michael ^a   Sicilia, Anita ^a   Tavares, Paul ^a   Beck, Jonathan ^a   Campbell, Tracy ^a   Lowe, Jessica ^a   Mead, Simon ^a,b   Rudge, Peter ^b   Collinge, John ^a,b   Jackson, Graham S ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b NATIONAL HOSPITAL FOR NEUROLOGY AND NEUROSURGERY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ISOPROTEIN; PRION PROTEIN;

ARTICLE; BINDING AFFINITY; BLOOD ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; HUMAN; IMMUNODETECTION; MAJOR CLINICAL STUDY; PRION DISEASE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SCORING SYSTEM; SENSITIVITY AND SPECIFICITY; SOLID STATE; SURFACE PROPERTY; VARIANT CREUTZFELDT JAKOB DISEASE;

EID: 79551681376     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(10)62308-2     Document Type: Article

References (42)

1. SB Prusiner Prions Proc Natl Acad Sci USA 95 1998 13363 13383
2. J Collinge Prion diseases of humans and animals: their causes and molecular basis Annu Rev Neurosci 24 2001 519 550
3. J Collinge, KC Sidle, J Meads, J Ironside, AF Hill Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD Nature 383 1996 685 690
4. AC Ghani, CA Donnelly, NM Ferguson, RM Anderson The transmission dynamics of BSE and vCJD C R Biol 325 2002 37 47
5. Spongiform Encephalopathy Advisory Committee SEAC 104/2 Estimating the prevalence of subclinical vCJD http://www.seac.gov.uk/papers/104-2.pdf 2010 (accessed Jan 7, 2011).
6. DA Hilton, AC Ghani, L Conyers Prevalence of lymphoreticular prion protein accumulation in UK tissue samples J Pathol 203 2004 733 739
7. Health Protection Analytical Team, Department of Health SEAC 100/6 Prevalence: resolving the discrepancy in current estimates http://www.seac.gov. uk/papers/paper100-6.pdf 2008 (accessed Jan 7, 2011).
8. Spongiform Encephalopathy Advisory Committee SEAC 100/2 Combining evidence from tissue surveys to estimate prevalence of subclinical vCJD http://www.seac.gov.uk/papers/paper100-2.pdf 2008 (accessed Jan 7, 2011).
9. JP Clewley, CM Kelly, N Andrews Prevalence of disease related prion protein in anonymous tonsil specimens in Britain: cross sectional opportunistic survey BMJ 338 2009 b1442
10. MF de Marco, J Linehan, ON Gill, JP Clewley, S Brandner Large-scale immunohistochemical examination for lymphoreticular prion protein in tonsil specimens collected in Britain J Pathol 222 2010 380 387
11. J Collinge, J Whitfield, E McKintosh Kuru in the 21st century - an acquired human prion disease with very long incubation periods Lancet 367 2006 2068 2074
12. AF Hill, S Joiner, J Linehan, M Desbruslais, PL Lantos, J Collinge Species barrier independent prion replication in apparently resistant species Proc Natl Acad Sci USA 97 2000 10248 10253
13. CA Llewelyn, PE Hewitt, RSG Knight Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion Lancet 363 2004 417 421
14. AH Peden, MW Head, DL Ritchie, JE Bell, JW Ironside Preclinical vCJD after blood transfusion in a PRNP codon 129 heterozygous patient Lancet 364 2004 527 529
15. SJ Wroe, S Pal, D Siddique Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report Lancet 368 2006 2061 2067
16. PE Hewitt, CA Llewelyn, J Mackenzie, RG Will Creutzfeldt-Jakob disease and blood transfusion: results of the UK Transfusion Medicine Epidemiological Review study Vox Sang 91 2006 221 230
17. A Peden, L McCardle, MW Head Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia Haemophilia 16 2010 296 304
18. JD Wadsworth, S Joiner, K Fox Prion infectivity in variant Creutzfeldt-Jakob disease rectum Gut 56 2007 90 94
19. MH Tattum, S Jones, S Pal, J Collinge, GS Jackson Discrimination between prion-infected and normal blood samples by protein misfolding cyclic amplification Transfusion 50 2010 996 1002
20. S Tzaban, G Friedlander, O Schonberger Protease-sensitive scrapie prion protein in aggregates of heterogeneous sizes Biochemistry 41 2002 12868 12875
21. MA Pastrana, G Sajnani, B Onisko Isolation and characterization of a proteinase K-sensitive PrP(Sc) fraction Biochemistry 45 2006 15710 15717
22. S Cronier, N Gros, MH Tattum Detection and characterization of proteinase K-sensitive disease-related prion protein with thermolysin Biochem J 416 2008 297 305
23. JDF Wadsworth, S Joiner, AF Hill Tissue distribution of protease resistant prion protein in variant Creutzfeldt-Jakob disease using a highly sensitive immunoblotting assay Lancet 358 2001 171 180
24. P Brown, RG Rohwer, BC Dunstan, C MacAuley, DC Gajdusek, WN Drohan The distribution of infectivity in blood components and plasma derivatives in experimental models of transmissible spongiform encephalopathy Transfusion 38 1998 810 816
25. P Brown, L Cervenáková, LM McShane, P Barber, R Rubenstein, WN Drohan Further studies of blood infectivity in an experimental model of transmissible spongiform encephalopathy, with an explanation of why blood components do not transmit Creutzfeldt-Jakob disease in humans Transfusion 39 1999 1169 1178
26. MH Tattum, S Jones, S Pal, A Khalili-Shirazi, J Collinge, GS Jackson A highly sensitive immunoassay for the detection of prion-infected material in whole human blood without the use of proteinase K Transfusion 50 2010 2619 2627
27. E Zobeley, E Flechsig, A Cozzio, E Masato, C Weissmann Infectivity of scrapie prions bound to a stainless steel surface Mol Med 5 1999 240 243
28. JA Edgeworth, GS Jackson, AR Clarke, C Weissmann, J Collinge Highly sensitive, quantitative cell-based assay for prions adsorbed to solid surfaces Proc Natl Acad Sci USA 106 2009 3479 3483
29. J Collinge, M Gorham, F Hudson Safety and efficacy of quinacrine in human prion disease (PRION-1 study): a patient-preference trial Lancet Neurol 8 2009 334 344
30. National Prion Clinic 2009 http://www.prion.ucl.ac.uk/clinic-services/ (accessed Jan 7, 2011).
31. S Poser, B Mollenhauer, A Krauss How to improve the clinical diagnosis of Creutzfeldt-Jakob disease Brain 122 1999 2345 2351
32. I Zerr, K Kallenberg, DM Summers Updated clinical diagnostic criteria for sporadic Creutzfeldt-Jakob disease Brain 132 2009 2659 2668
33. PE Hewitt, CA Llewelyn, J Mackenzie, RG Will Three reported cases of variant Creutzfeldt-Jakob disease transmission following transfusion of labile blood components Vox Sang 91 2006 348
34. L Gregori, N McCombie, D Palmer Effectiveness of leucoreduction for removal of infectivity of transmissible spongiform encephalopathies from blood Lancet 364 2004 529 531
35. L Gregori, PV Gurgel, JT Lathrop Reduction in infectivity of endogenous transmissible spongiform encephalopathies present in blood by adsorption to selective affinity resins Lancet 368 2006 2226 2230
36. Advisory committee on the safety of blood tissues and organs Minutes of the eighth meeting, 27 October 2009. Department of Health http://www.dh.gov.uk/ prod-consum-dh/groups/dh-digitalassets/@dh/@ab/documents/digitalasset/dh-112477. pdf (accessed Jan 7, 2011).
37. J Collinge Variant Creutzfeldt-Jakob disease Lancet 354 1999 317 323
38. JR Silveira, GJ Raymond, AG Hughson The most infectious prion protein particles Nature 437 2005 257 261
39. PD Minor Technical aspects of the development and validation of tests for variant Creutzfeldt-Jakob disease in blood transfusion Vox Sang 86 2004 164 170
40. B Barcikowska, H Kwiecinski, PP Liberski, J Kowalski, P Brown, DC Gajdusek Creutzfeldt-Jakob disease with Alzheimer-type A beta-reactive amyloid plaques Histopathology 26 1995 445 450
41. P Saa, J Castilla, C Soto Presymptomatic detection of prions in blood Science 313 2006 92 94
42. RE Duncan, MB Delatycki, SJ Collins, A Boyd, CL Masters, J Savulescu Ethical considerations in presymptomatic testing for variant CJD J Med Ethics 31 2005 625 630