Evaluation of the wound healing potentials of two subspecies of hypericum perforatum on cultured NIH3T3 fibroblasts

Phytotherapy Research

Volumn 25, Issue 2, 2011, Pages 208-214

  Dikmen, Miriş ^a   Öztürk, Yusuf ^a   Sagratini, Gianni ^b   Ricciutelli, Massimo ^b   Vittori, Sauro ^b   Maggi, Filippo ^b  

^a ANADOLU UNIVERSITY   (Turkey)

^b UNIVERSITY OF CAMERINO   (Italy)

Author keywords

Hypericum perforatum; NIH3T3 fibroblast cells; wound healing

Indexed keywords

CHLOROGENIC ACID; COLLAGEN; HYPERFORIN; HYPERICIN; HYPERICUM PERFORATUM EXTRACT; HYPERIN; ISOQUERCITRIN; QUERCITRIN; RUTOSIDE;

ARTICLE; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN 3T3; CHEMICAL COMPOSITION; COLLAGEN SYNTHESIS; CONCENTRATION RESPONSE; DRUG CYTOTOXICITY; FIBROBLAST; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYPERICUM PERFORATUM; MITOSIS RATE; MORPHOMETRICS; NONHUMAN; SUBSPECIES; WOUND HEALING;

CENTELLA ASIATICA; HUMAN PAPILLOMAVIRUS; HYPERICUM PERFORATUM;

EID: 79551665249     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.3243     Document Type: Article

References (29)

1. Anon 1999. Monograph: Hypericum. Altern Med Rev 4: 190-192.
2. Benkiki N, Kaboucheb Z, Tillequin F, Verite P, Chosson E, Seguin E,. 2003. A new polyisoprenylated phloroglucinol derivative from Hypericum perfoliatum (Clusiaceae). Z Naturforsch 58C: 655-658.
3. Blumenthal M,. 2003. The ABC Clinical Guide to Herbs. American Botanical Council: Austin, Texas, 323-334.
4. Bretscher MS,. 1988. Fibroblasts on the move. J Cell Biol 106: 235-237.
5. Diegelman RF, Kim JC, Lindblad WJ, Cohen IK,. 1987. Collection of leucocytes, fibroblasts and collagen within an implantable reservoir tube during tissue repair. J Leukoc Biol 42: 667-672.
6. Duke JA,. 1985. Handbook of Medicinal Herbs. CRC Press: Boca Raton, FL, 242-243.
7. Dymock W, Warden EJH, Hooper D,. 1890. Pharmacographia Indica. Thacker Spink and Co: Calcutta, 49-50.
8. Gherard E,. 1991. Growth factor and cell movement. Eur J Cancer 27: 403-405.
9. Graham MF, Diegelman RF, Cohen IK,. 1984. An in vitro model of fibroplasia: simultaneous quantification of fibroblast proliferation, migration, and collagen synthesis. Proc Soc Exp Biol Med 176: 302-308.
10. Johnson KE,. 1991. Histology and Cell Biology. Williams and Wilkins: Baltimore, 65-101.
11. Jones ML,. 2002. Connective tissues and stains. In Theory and Practice of Histological Techniques, Bancroft JD, Gamble M, (eds). Churchill Livingstone: London, 153.
12. Korkmaz S, Öztürk Y, Öztürk N,. 2001. Wound-healing activity of St John's Wort on chicken embryonic fibroblasts. Fundam Clin Pharmacol 15: 104.
13. Korkmaz S, Zeytinoglu H, Zeytinoglu M, Aydın S, Öztürk Y, Baser KHC,. 2000. Testing the wound-healing activity in T15 fibroblast culture: a morphometric analysis. Altern Lab Anim 28: 41-51.
14. Lavagna SM, Secci D, Chimenti P, Bonsignore L, Ottaviani A, Bizzarri B,. 2001. Efficacy of Hypericum and Calendula oils in the epithelial reconstruction of surgical wounds in childbirth with caesarean section. Farmaco 56: 451-453.
15. Maggi F, Ferretti G, Pocceschi N, Menghini L, Ricciutelli M,. 2004. Morphological, histochemical and phytochemical investigation of the genus Hypericum of the Central Italy. Fitoterapia 75: 702-711.
16. Maquart FX, Bellon G, Gillery P, Wegrowski Y, Borel JP,. 1990. Stimulation of collagen synthesis in fibroblast cultures by triterpene extracted from Centella asiatica. Connect Tissue Res 24: 107-120.
17. Mukherjee PK, Suresh B,. 2000a. The evaluation of wound-healing potential of Hypericum hookerianum leaf and stem extracts. J Altern Complement Med 6: 61-69.
18. Mukherjee PK, Suresh B,. 2000b. Studies on in vivo wound-healing activity of leaf extract of Hypericum mysorense with different wound model in rats. Nat Prod Sci 6: 73-78.
19. Mukherjee PK, Verpoorte R, Suresh B,. 2000. Evaluation of in-vivo wound healing activity of Hypericum patulum (Family: Hypericaceae) leaf extract on different wound model in rats. J Ethnopharmacol 70: 315-321.
20. Öztürk N, Korkmaz S, Öztürk Y,. 2007. Wound-healing activity of St. John's Wort (Hypericum perforatum L.) on chicken embryonic fibroblasts. J Ethnopharmacol 111: 33-39.
21. Öztürk N, Korkmaz S, Öztürk Y, Başer KHC,. 2006. Effects of gentiopicroside, sweroside and swertiamarine, secoiridoids from Gentian (Gentiana lutea ssp. symphyandra), on cultured chicken embryonic fibroblasts. Planta Med 72: 289-294.
22. Rao SG, Udupa AL, Udupa SL, Rao PGM, Rao G, Kulkarni DR,. 1991. Calendula and Hypericum: two homeopathic drugs promoting wound healing in rats. Fitoterapia 6: 508-510.
23. Roth L,. 1953. Untersuchung verschiedener Johanniskrautarten auf den Gehalt an Hypericin. Dtsch Apoth Ztg 63: 653.
24. Schreier T, Degen E, Baschong W,. 1993. Fibroblast migration and proliferation during in vitro wound healing. A quantitative comparison between various growth factors and a low molecular weight blood dialysate in the clinic to normally impaired wound healing. Res Exp Med 193: 195-205.
25. Wink YK,. 2001. Herbal treatment of insomnia. Hong Kong Med J 7: 392-402.
26. Winkelmann K, Heilmann J, Zerbe O, Rali T, Sticher O,. 2001. New prenylated bi-and tricyclic phloroglucinol derivatives from Hypericum papuanum. J Nat Prod 64: 701-706. (Pubitemid 32565913)
27. Woodley DT, O'Keefe EJ, Prunerias M,. 1985. Cutaneous wound healing: a model for cell-matrix interaction. J Am Acad Dermatol 12: 420-433.
28. Yeşilada E, Honda G, Sezik E, et al. 1995. Traditional medicine in Turkey. V. Folk medicine in the inner Taurus mountains. J Ethnopharmacol 46: 133-152.
29. Yeşilada E, Honda G, Sezik E, Tabata M, Goto D, Ikeshiro Y,. 1993. Traditional medicine in Turkey. IV. Folk medicine in the Mediterranean subdivision. J Ethnopharmacol 3: 31-38.