-
1
-
-
0031730504
-
Weak opioids - an educational substitute for morphine
-
Grond, S.; Meuser, T. Weak opioids - an educational substitute for morphine? Curr. Opin. Anesthesiol., 1998, 11, 559-565.
-
(1998)
Curr. Opin. Anesthesiol
, vol.11
, pp. 559-565
-
-
Grond, S.1
Meuser, T.2
-
2
-
-
0023720412
-
Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids
-
Hennies, M. H.; Friderichs, E.; Schneider, J. Receptor binding, analgesic and antitussive potency of tramadol and other selected opioids. Arzneimittelforschung, 1988, 38, 877-880.
-
(1988)
Arzneimittelforschung
, vol.38
, pp. 877-880
-
-
Hennies, M.H.1
Friderichs, E.2
Schneider, J.3
-
3
-
-
0026512239
-
Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an "atypical" opioid analgesic
-
Raffa, R. B.; Friderichs, E.; Reimann, W.; Shank, R. P.; Codd, E. E.; Vaught, J. L. Opioid and nonopioid components independently contribute to the mechanism of action of tramadol, an "atypical" opioid analgesic. J. Pharmacol. Exp. Ther., 1992, 260, 275-285.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.260
, pp. 275-285
-
-
Raffa, R.B.1
Friderichs, E.2
Reimann, W.3
Shank, R.P.4
Codd, E.E.5
Vaught, J.L.6
-
4
-
-
0026583699
-
Efficacy and safety of tramadol versus morphine for moderate and severe postoperative pain with special regard to respiratory depression
-
Houmes, R. J. M.; Voets, M. A.; Verkaaik, A.; Erdmann, W.; Lachmann, B. Efficacy and safety of tramadol versus morphine for moderate and severe postoperative pain with special regard to respiratory depression. Anesth. Analg., 1992, 74, 510-514.
-
(1992)
Anesth. Analg.
, vol.74
, pp. 510-514
-
-
Houmes, R.J.M.1
Voets, M.A.2
Verkaaik, A.3
Erdmann, W.4
Lachmann, B.5
-
5
-
-
0026575516
-
Tramadol: Pain relief by an opioid without depression of respiration
-
Vickers, M.; O'Flaherty, D.; Szekely, S. M.; Read, M.; Yoshizumi, J. Tramadol: Pain relief by an opioid without depression of respiration. Anaesthesia, 1992, 47, 291-296.
-
(1992)
Anaesthesia
, vol.47
, pp. 291-296
-
-
Vickers, M.1
O'Flaherty, D.2
Szekely, S.M.3
Read, M.4
Yoshizumi, J.5
-
6
-
-
0026011542
-
Abuse potential and pharmacological comparison of tramadol and morphine
-
Preston, K.L.; Jasinski, D.R.; Testa, M. Abuse potential and pharmacological comparison of tramadol and morphine. Drug Alcohol Depend., 1991, 27, 7-17.
-
(1991)
Drug Alcohol Depend.
, vol.27
, pp. 7-17
-
-
Preston, K.L.1
Jasinski, D.R.2
Testa, M.3
-
7
-
-
0023473144
-
Obstetric analgesia with tramadol- results of a prospective randomised comparison with pethidine
-
Husslein P.; Kubista, E.; Egarter, C. Obstetric analgesia with tramadol- results of a prospective randomised comparison with pethidine. Z. Geburtsh. Perinatol., 1987, 191, 234-237.
-
(1987)
Z. Geburtsh. Perinatol.
, vol.191
, pp. 234-237
-
-
Husslein, P.1
Kubista, E.2
Egarter, C.3
-
8
-
-
0029053618
-
Efficacy and safety of oral tramadol and pentazocine for postoperative pain following prolapsed intervertebral disc repair
-
Kupers, R.; Callebaut, V.; Debois, V.; Camu, F.; Verborgh, C.; Coppejans, H.; Adriaensen, H. Efficacy and safety of oral tramadol and pentazocine for postoperative pain following prolapsed intervertebral disc repair. Acta Anaesth. Belg., 1995, 46, 31-37.
-
(1995)
Acta Anaesth. Belg.
, vol.46
, pp. 31-37
-
-
Kupers, R.1
Callebaut, V.2
Debois, V.3
Camu, F.4
Verborgh, C.5
Coppejans, H.6
Adriaensen, H.7
-
9
-
-
76049106897
-
Tramadol as an analgesic for mild to moderate cancer pain
-
Leppert, W. Tramadol as an analgesic for mild to moderate cancer pain. Pharmacol. Rep., 2009, 61, 978-992.
-
(2009)
Pharmacol. Rep.
, vol.61
, pp. 978-992
-
-
Leppert, W.1
-
10
-
-
42649083655
-
Determination of tramadol and O-desmethyltramadol in human plasma by high-performance liquid chromatography with mass spectrometry detection
-
Vlase, L.; Leucuta, S.E.; Imre, S. Determination of tramadol and O-desmethyltramadol in human plasma by high-performance liquid chromatography with mass spectrometry detection. Talanta, 2008, 75, 1104-1109.
-
(2008)
Talanta
, vol.75
, pp. 1104-1109
-
-
Vlase, L.1
Leucuta, S.E.2
Imre, S.3
-
11
-
-
58749084861
-
Ocena analgezji i objawow niepozadanych tramadolu I dihydrokodeiny o kontrolowanym uwalnianiu u chorych z bolem nowotworowym - na podstawie zmodyfikowanej skali ESAS (Polish)
-
Leppert, W.; Majkowicz, M. Ocena analgezji i objawow niepozadanych tramadolu I dihydrokodeiny o kontrolowanym uwalnianiu u chorych z bolem nowotworowym - na podstawie zmodyfikowanej skali ESAS (Polish). Wspolcz. Onkol., 2008, 12, 246-254.
-
(2008)
Wspolcz. Onkol.
, vol.12
, pp. 246-254
-
-
Leppert, W.1
Majkowicz, M.2
-
12
-
-
0031839871
-
The visceral and somatic antinociceptive effects of dihydrocodeine and its metabolite, dihydromorphine. A cross-over study with extensive and quinidine-induced poor matabolizers
-
Wilder-Smith, C.H.; Hufschmid, E.; Thormann, W. The visceral and somatic antinociceptive effects of dihydrocodeine and its metabolite, dihydromorphine. A cross-over study with extensive and quinidine-induced poor matabolizers. Br. J. Clin. Pharmacol., 1998, 45, 575-581.
-
(1998)
Br. J. Clin. Pharmacol.
, vol.45
, pp. 575-581
-
-
Wilder-Smith, C.H.1
Hufschmid, E.2
Thormann, W.3
-
13
-
-
14844360833
-
Influence of CYP2D6 genetics on opioid kinetics, metabolism and response
-
Mikus, G.; Weiss, J. Influence of CYP2D6 genetics on opioid kinetics, metabolism and response. Curr. Pharmacogenom., 2005, 3, 43-52.
-
(2005)
Curr. Pharmacogenom.
, vol.3
, pp. 43-52
-
-
Mikus, G.1
Weiss, J.2
-
14
-
-
0024990497
-
Postoperative patient-controlled analgesia with tramadol: Analgesic efficacy and minimum effective concentrations
-
Lehmann, K.A.; Kratzenberg, U.; Schroeder-Bark, B.; Horrichs- Haermeyer, G. Postoperative patient-controlled analgesia with tramadol: analgesic efficacy and minimum effective concentrations. Clin. J. Pain, 1990, 6, 212-220.
-
(1990)
Clin. J. Pain
, vol.6
, pp. 212-220
-
-
Lehmann, K.A.1
Kratzenberg, U.2
Schroeder-Bark, B.3
Horrichs-Haermeyer, G.4
-
15
-
-
0025976015
-
Polymorphic metabolism of opioid narcotic drugs: Possible clinical implications
-
Mikus, G.; Somogyi, A.A.; Bochner, F.; Chen, Z.R. Polymorphic metabolism of opioid narcotic drugs: possible clinical implications. Ann. Acad. Med. Singapore, 1991, 20, 9-12.
-
(1991)
Ann. Acad. Med. Singapore
, vol.20
, pp. 9-12
-
-
Mikus, G.1
Somogyi, A.A.2
Bochner, F.3
Chen, Z.R.4
-
16
-
-
0141626841
-
Impact of CYP2D6 genotype on postoperative tramadol analgesia
-
Stamer, U.M.; Lehnen, K.; Höthker, F.; Bayerer, B.; Wolf, S.; Hoeft, A.; Stuber, F. Impact of CYP2D6 genotype on postoperative tramadol analgesia. Pain, 2003, 105, 231-238.
-
(2003)
Pain
, vol.105
, pp. 231-238
-
-
Stamer, U.M.1
Lehnen, K.2
Höthker, F.3
Bayerer, B.4
Wolf, S.5
Hoeft, A.6
Stuber, F.7
-
17
-
-
34250614223
-
Concentrations of tramadol and o-desmethyltramadol enantiomers in different CY2D6 genotypes
-
Stamer, U.; Musshoff, F.; Kobilay, M.; Madea, B.; Hoeft, A.; Stuber, F. Concentrations of tramadol and o-desmethyltramadol enantiomers in different CY2D6 genotypes. Clin. Pharmacol. Ther., 2007, 82, 41-47.
-
(2007)
Clin. Pharmacol. Ther.
, vol.82
, pp. 41-47
-
-
Stamer, U.1
Musshoff, F.2
Kobilay, M.3
Madea, B.4
Hoeft, A.5
Stuber, F.6
-
18
-
-
33846598505
-
Pharmacokinetics of tramadol enantiomers and their respective phase I metabolites in relation to CYP2D6 phenotype
-
García-Quetglas, E.; Azanza, J. R.; Sádaba, B.; Muñoz, M. J.; Gil, I.; Campanero, M. A. Pharmacokinetics of tramadol enantiomers and their respective phase I metabolites in relation to CYP2D6 phenotype. Pharmacol. Res., 2007, 55, 122-130.
-
(2007)
Pharmacol. Res.
, vol.55
, pp. 122-130
-
-
García-Quetglas, E.1
Azanza, J.R.2
Sádaba, B.3
Muñoz, M.J.4
Gil, I.5
Campanero, M.A.6
-
19
-
-
38349163777
-
Effects of the CYP2D6 gene duplication on the pharmacokinetics and pharmacodynamics of tramadol
-
Kirchheiner, J.; Keulen, J-T.H.A.; Bauer, S.; Roots, I.; Brockmöller, J. Effects of the CYP2D6 gene duplication on the pharmacokinetics and pharmacodynamics of tramadol. J. Clin. Psychopharmacol., 2008, 28, 78-83.
-
(2008)
J. Clin. Psychopharmacol
, vol.28
, pp. 78-83
-
-
Kirchheiner, J.1
Keulen, J-T.H.A.2
Bauer, S.3
Roots, I.4
Brockmöller, J.5
-
20
-
-
51449102329
-
Respiratory depression with tramadol in a patient with renal impairment and CYP2D6 gene duplication
-
Stamer, U.; Stuber, F.; Muders, T.; Musshoff, F. Respiratory depression with tramadol in a patient with renal impairment and CYP2D6 gene duplication. Anesth. Analg., 2008, 107, 926-929.
-
(2008)
Anesth. Analg.
, vol.107
, pp. 926-929
-
-
Stamer, U.1
Stuber, F.2
Muders, T.3
Musshoff, F.4
-
21
-
-
0019847479
-
Biotransformation of tramadol in man and animal
-
Lintz, W.; Erlacin, S.; Frankus, E.; Uragg, H. Biotransformation of tramadol in man and animal. Arznneimittelforschung, 1981, 31, 1932-1943.
-
(1981)
Arznneimittelforschung
, vol.31
, pp. 1932-1943
-
-
Lintz, W.1
Erlacin, S.2
Frankus, E.3
Uragg, H.4
-
22
-
-
0026649268
-
The metabolism of tramadol by human liver microsomes
-
Paar, W.D.; Frankus, P.; Dengler, H.J. The metabolism of tramadol by human liver microsomes. Clin. Invest., 1992, 70, 708-710.
-
(1992)
Clin. Invest.
, vol.70
, pp. 708-710
-
-
Paar, W.D.1
Frankus, P.2
Dengler, H.J.3
-
23
-
-
0031460240
-
Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol
-
Paar, W.D.; Poche, S.; Gerloff, J.; Dengler, H.J. Polymorphic CYP2D6 mediates O-demethylation of the opioid analgesic tramadol. Eur. J. Clin. Pharmacol., 1997, 53, 235-239.
-
(1997)
Eur. J. Clin. Pharmacol.
, vol.53
, pp. 235-239
-
-
Paar, W.D.1
Poche, S.2
Gerloff, J.3
Dengler, H.J.4
-
24
-
-
77954156991
-
Dihydrocodeine as an analgesic for the treatment of moderate to severe chronic pain
-
Leppert, W. Dihydrocodeine as an analgesic for the treatment of moderate to severe chronic pain. Curr. Drug Metab., 2010, 11, 494-506.
-
(2010)
Curr. Drug Metab
, vol.11
, pp. 494-506
-
-
Leppert, W.1
-
25
-
-
0031018715
-
The analgesic tramadol has minimal effect on gastrointestinal motor function
-
Wilder - Smith, C.H.; Bettiga, A. The analgesic tramadol has minimal effect on gastrointestinal motor function. Br. J. Clin. Pharmacol., 1997, 43, 71-75.
-
(1997)
Br. J. Clin. Pharmacol
, vol.43
, pp. 71-75
-
-
Wilder-Smith, C.H.1
Bettiga, A.2
-
26
-
-
13244260911
-
The role of tramadol in cancer pain treatment- a review. Support
-
Leppert, W.; Luczak, J. The role of tramadol in cancer pain treatment- a review. Support. Care Cancer, 2005, 13, 5-17.
-
(2005)
Care Cancer
, vol.13
, pp. 5-17
-
-
Leppert, W.1
Luczak, J.2
-
27
-
-
13544249943
-
Genetic polymorphism of cytochrome P450 2D6 (CYP2D6): Clinical consequences, evolutionary aspects and functional diversity
-
Ingelman-Sundberg, M. Genetic polymorphism of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity. Pharmacogenom. J., 2005, 5, 6-13.
-
(2005)
Pharmacogenom. J.
, vol.5
, pp. 6-13
-
-
Ingelman-Sundberg, M.1
-
28
-
-
0033402882
-
The effect of tramadol in painful polyneuropathy in relation to serum drug and metabolite levels
-
Sindrup, S.H.; Madsen, C.; Brøsen, K.; Jensen, T.S. The effect of tramadol in painful polyneuropathy in relation to serum drug and metabolite levels. Clin. Pharmacol. Ther., 1999, 66, 636-641.
-
(1999)
Clin. Pharmacol. Ther.
, vol.66
, pp. 636-641
-
-
Sindrup, S.H.1
Madsen, C.2
Brøsen, K.3
Jensen, T.S.4
-
29
-
-
0028785119
-
The cost of constipation in morphine patients and the economic possibilities with tramadol
-
Duggan, A.K. The cost of constipation in morphine patients and the economic possibilities with tramadol. Br. J. Med. Econom., 1995, 9, 21-29.
-
(1995)
Br. J. Med. Econom.
, vol.9
, pp. 21-29
-
-
Duggan, A.K.1
-
30
-
-
13244300015
-
Tramadol and cancer pain
-
Leppert, W.; Luczak, J.; Oliver, D. Tramadol and cancer pain. Eur. J. Palliat. Care, 2002, 9, 49-51.
-
(2002)
Eur. J. Palliat. Care
, vol.9
, pp. 49-51
-
-
Leppert, W.1
Luczak, J.2
Oliver, D.3
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