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Volumn 34, Issue 4, 2011, Pages 307-316
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Determination of urapidil hydrochloride in rabbit plasma by LC-MS-MS and its application to a pharmacokinetic study
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Author keywords
LC MS MS; pharmacokinetics; plasma; urapidil hydrochloride
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Indexed keywords
CALIBRATION PLOT;
CHROMATOGRAPHIC SEPARATIONS;
FRAGMENT IONS;
GRADIENT ELUTION;
INTERNAL STANDARDS;
LC-MS-MS;
LOWER LIMIT OF QUANTITATIONS;
MOBILE PHASE;
MULTIPLE-REACTION MONITORING MODES;
PHARMACOKINETIC STUDIES;
POSITIVE ION MODE;
PROTEIN PRECIPITATION;
RABBIT PLASMAS;
SAMPLE PREPARATION;
SELECTIVE LIQUID CHROMATOGRAPHY;
TRICHLOROACETIC ACID;
URAPIDIL;
ACETONITRILE;
ELECTROSPRAY IONIZATION;
LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
PHARMACOKINETICS;
PLASMAS;
ACETONITRILE;
DOXAPRAM;
TRICHLOROACETIC ACID;
URAPIDIL;
WATER;
ANIMAL EXPERIMENT;
AREA UNDER THE CURVE;
ARTICLE;
DRUG BLOOD LEVEL;
DRUG CLEARANCE;
DRUG DISTRIBUTION;
DRUG HALF LIFE;
DRUG STABILITY;
ELECTROSPRAY;
EXPERIMENTAL RABBIT;
LIQUID CHROMATOGRAPHY;
MALE;
NONHUMAN;
PLASMA CONCENTRATION-TIME CURVE;
PRECIPITATION;
SENSITIVITY ANALYSIS;
TANDEM MASS SPECTROMETRY;
ORYCTOLAGUS CUNICULUS;
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EID: 79551639435
PISSN: 10826076
EISSN: 1520572X
Source Type: Journal
DOI: 10.1080/10826076.2011.547413 Document Type: Article |
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Times cited : (19)
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References (13)
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