Caloric restriction and antiaging effects

Annals of Nutrition and Metabolism

Volumn 58, Issue 1, 2011, Pages 42-48

  Xiang, Lan ^a   He, Guoqing ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Aging; Caloric restriction; Energy metabolism; Lifespan

Indexed keywords

ADIPOSE TISSUE; AGING; BODY SIZE; BODY TEMPERATURE; CALORIC RESTRICTION; CELL DAMAGE; DIET RESTRICTION; ENERGY METABOLISM; GROWTH INHIBITION; HUMAN; HYPERCORTICOSTERONEMIA; HYPERGLYCEMIA; HYPERINSULINEMIA; HYPOTHERMIA; LIPID METABOLISM; LIPID STORAGE; MATURATION; METABOLIC DISORDER; METABOLIC RATE; NEUROENDOCRINE SYSTEM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; REPRODUCTION; REVIEW; SIGNAL TRANSDUCTION; STRESS;

ADIPOSE TISSUE; AGING; ANIMALS; BODY TEMPERATURE; CALORIC RESTRICTION; DIET, REDUCING; DIETARY PROTEINS; ENERGY METABOLISM; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LIPIDS; NEUROSECRETORY SYSTEMS; SIGNAL TRANSDUCTION;

EID: 79551627059     PISSN: 02506807     EISSN: None     Source Type: Journal    
DOI: 10.1159/000323748     Document Type: Review

References (91)

1. McCay CM, Crowell MF, Maynard LA: The effect of retarded growth upon the length of life span and upon the ultimate body size. J Nutr 1935; 10: 63-79.
2. Anderson RM, Weindruch R: Metabolic reprogramming, caloric restriction and aging. Trends Endocrinol Metab 2010; 21: 134-141.
3. Kennedy BK, Steffen KK, Kaeberlein M: Ruminations on dietary restriction and aging. Cell Mol Life Sci 2007; 64: 1323-1328. (Pubitemid 46889228)
4. Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Sinclair D, Tatar M: Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 2004; 430: 686-689. (Pubitemid 39061685)
5. Masoro EJ: Caloric restriction and aging: an update. Exp Gerontol 2000; 35: 299-305. (Pubitemid 30314687)
6. Holliday R: Food, reproduction and longevity: is the extended lifespan of calorie-restricted animals an evolutionary adaptation? Bioessays 1989; 10: 125-127.
7. Nelson JF: Neuroendocrine involvement in the retardation of aging by dietary restriction: a hypothesis; in Yu BP (ed): Modulation of Aging Processes by Dietary Restriction. Boca Raton, CRC, 1994, pp 37-55.
8. Ahima RS, Prabakaran D, Mantzoros C, Qu D, Lowell B, Maratos-Flier E, Flier JS: Role of leptin in the neuroendocrine response to fasting. Nature 1996; 382: 250-252. (Pubitemid 26251358)
9. Overton JM, Williams TD, Chambers JB, Rashotte ME: Central leptin infusion attenuates the cardiovascular and metabolic effects of fasting in rats. Hypertension 2001; 37: 663-669. (Pubitemid 32199046)
10. Salway JG: Metabolism at a Glance. Oxford, Blackwell Science, 1999.
11. Hashimoto T, Cook WS, Qi C, Yeldandi AV, Reddy JK, Rao MS: Defect in peroxisome proliferator-activated receptor-α-inducible fatty acid oxidation determines the severity of hepatic steatosis in response to fasting. J Biol Chem 2000; 275: 28918-28928.
12. Kersten S, Seydoux J, Peters JM, Gonzalez FJ, Desvergne B, Wahli W: Peroxisome proliferator- activated receptor- α mediates the adaptive response to fasting. J Clin Invest 1999; 103: 1489-1498.
13. McCarter RJ, Palmer J: Energy metabolism and aging: a lifelong study of Fischer 344 rats. Am J Physiol 1992; 263(pt 1):E448-E452.
14. Higami Y, Pugh TD, Page GP, Allison DB, Prolla TA, Weindruch R: Adipose tissue energy metabolism: altered gene expression profile of mice subjected to long-term caloric restriction. FASEB J 2004; 18: 415-417.
15. Lauzurica N, García-García L, Pinto S, Fuentes JA, Delgado M: Changes in NPY and POMC, but not serotonin transporter, following a restricted feeding/repletion protocol in rats. Brain Res 2010; 1313: 103-112.
16. Shimokawa T, Kumar MV, Lane MD: Effect of a fatty acid synthase inhibitor on food intake and expression of hypothalamic neuropeptides. Proc Natl Acad Sci USA 2002; 99: 66-71. (Pubitemid 34060317)
17. Xu B, Kalra PS, Farmerie WG, Kalra SP: Daily changes in hypothalamic gene expression of neuropeptide Y, galanin, proopiomelanocortin, and adipocyte leptin gene expression and secretion: effects of food restriction. Endocrinology 1999; 140: 2868-2875. (Pubitemid 32245168)
18. Sonntag WE, Xu X, Ingram RL, D'Costa A: Moderate caloric restriction alters the subcellular distribution of somatostatin mRNA and increases growth hormone pulse amplitude in aged animals. Neuroendocrinology 1995; 61: 601-608.
19. Shimokawa I, Higami Y: A role for leptin in the anti-aging action of dietary restriction: a hypothesis. Aging (Milano) 1999; 11: 380-382. (Pubitemid 30136668)
20. Breese CR, Ingram RL, Sonntag WE: Influence of age and long-term dietary restriction on plasma insulin-like growth factor-1 (IGF- 1), IGF-1 gene expression, and IGF-1 binding proteins. J Gerontol 1991; 46:B180-B187.
21. Bronson FH: Food-restricted, prepubertal, female rats: rapid recovery of luteinizing hormone pulsing with excess food, and full recovery of pubertal development with gonadotropin- releasing hormone. Endocrinology 1986; 118: 2483-2487. (Pubitemid 16058423)
22. Hamilton GD, Bronson FH: Food restriction and reproductive development: male and female mice and male rats. Am J Physiol 1986; 250:R370-R376.
23. Sirotkin AV, Chrenkova M, Nitrayova S, Patras P, Darlak K, Valenzuela F, Pinilla L, Tena- Sempere M: Effects of chronic food restriction and treatments with leptin or ghrelin on different reproductive parameters of male rats. Peptides 2008; 29: 1362-1368.
24. Campbell GA, Kurcz M, Marshall S, Meites J: Effects of starvation in rats on serum levels of follicle stimulating hormone, luteinizing hormone, thyrotropin, growth hormone and prolactin: response to LH-releasing hormone and thyrotropin-releasing hormone. Endocrinology 1977; 100: 580-587. (Pubitemid 8033960)
25. Grizard G, Artonne C, Grizard J, Boucher D: Effect of short-term starvation on Leydig cell function in adult rats. Arch Androl 1997; 38: 207-214. (Pubitemid 27243578)
26. Sabatino F, Masoro EJ, McMahan CA, Kuhn RW: Assessment of the role of the glucocorticoid system in aging processes and in the action of food restriction. J Gerontol 1991; 46:B171-B179.
27. Masoro EJ, Compton C, Yu BP, Bertrand H: Temporal and compositional dietary restrictions modulate age-related changes in serum lipids. J Nutr 1983; 113: 880-892. (Pubitemid 13136660)
28. Yamaza H, Komatsu T, Chiba T, Toyama H, To K, Higami Y, Shimokawa I: A transgenic dwarf rat model as a tool for the study of calorie restriction and aging. Exp Gerontol 2004; 39: 269-272. (Pubitemid 38169420)
29. McCarter RJ, McGee JR: Transient reduction of metabolic rate by food restriction. Am J Physiol 1989; 257:E175-E179.
30. McCarter RJ, Palmer J: Energy metabolism and aging: a lifelong study of Fischer 344 rats. Am J Physiol 1992; 263(pt 1):E448-E452.
31. Koizumi A, Wada Y, Tuskada M, Kayo T, Naruse M, Horiuchi K, Mogi T, Yoshioka M, Sasaki M, Miyamaura Y, Abe T, Ohtomo K, Walford RL: A tumor preventive effect of dietary restriction is antagonized by a high housing temperature through deprivation of torpor. Mech Ageing Dev 1996; 92: 67-82. (Pubitemid 27052775)
32. Ingram DK, Zhu M, Mamczarz J, Zou S, Lane MA, Roth GS, deCabo R: Calorie restriction mimetics: an emerging research field. Aging Cell 2006; 5: 97-108. (Pubitemid 44056501)
33. Roth GS, Lane MA, Ingram DK, Mattison JA, Elahi D, Tobin JD, Muller D, Metter EJ: Biomarkers of caloric restriction may predict longevity in humans. Science 2002; 297: 811. (Pubitemid 34839625)
34. Barzilai N, Banerjee S, Hawkins M, Chen W, Rossetti L: Caloric restriction reverses hepatic insulin resistance in aging rats by decreasing visceral fat. J Clin Invest 1998; 101: 1353-1361. (Pubitemid 28166832)
35. Schwartz MW, Woods SC, Porte D Jr, Seeley RJ, Baskin DG: Central nervous system control of food intake. Nature 2000; 404: 661-671. (Pubitemid 30205071)
36. Kadowaki T, Hara K, Yamauchi T, Terauchi Y, Tobe K, Nagai R: Molecular mechanism of insulin resistance and obesity. Exp Biol Med (Maywood) 2003; 228: 1111-1117. (Pubitemid 37413667)
37. Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, Bihain BE, Lodish HF: Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Natl Acad Sci USA 2001; 98: 2005-2010. (Pubitemid 32165613)
38. Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara, K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T: The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 2001; 7: 941-946. (Pubitemid 32756432)
39. Yamauchi T, Kamon K, Minokoshi Y, Ito Y, Waki H, Uchida S, Yamashita S, Noda M, Kita S, Ueki K, Eto K, Akanuma Y, Froguel P, Foufelle F, Ferre P, Carling D, Kimura S, Nagai R, Kahn BB, Kadowaki T: Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase. Nat Med 2002; 8: 1288-1295. (Pubitemid 35373562)
40. Zhu M, Miura J, Lu LX, Bernier M, DeCabo R, Lane MA, Roth GS, Ingram DK: Circulating adiponectin levels increase in rats on caloric restriction: the potential for insulin sensitization. Exp Gerontol 2004; 39: 1049-1059. (Pubitemid 38952885)
41. Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui JM, Fung C, Karim R, Lin R, Samarasinghe D, Liddle C, Weltman M, George J: NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 2002; 35: 373-379. (Pubitemid 34106377)
42. Unger RH, Orci L: Lipoapoptosis: its mechanism and its diseases. Biochem Biophys Acta 2002; 1585: 202-212. (Pubitemid 36092084)
43. Kristal BS, Yu BP: An emerging hypothesis: synergistic induction of aging by free radicals and Maillard reactions. J Gerontol 1992; 47:B107-B114.
44. Czaja MJ: Liver injury in the setting of steatosis: crosstalk between adipokine and cytokine. Hepatology 2004; 40: 19-22. (Pubitemid 38868918)
45. Chung HY, Kim HJ, Kim KW, Choi JS, Yu BP: Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction. Microsc Res Tech 2002; 59: 264-272. (Pubitemid 35332944)
46. Shimokawa I, Higami Y: Leptin signaling and aging: insight from caloric restriction. Mech Ageing Dev 2001; 122: 1511-1519. (Pubitemid 32757129)
47. Rao MS, Reddy JK: Peroxisomal β-oxidation and steatohepatitis. Semin Liver Dis 2001; 21: 43-55.
48. Lemberger T, Saladin R, Vázquez M, Assimacopoulos F, Staels B, Desvergne B, Wahli W, Auwerx J: Expression of the peroxisome proliferator-activated receptor- α gene is stimulated by stress and follows a diurnal rhythm. J Biol Chem 1996; 271: 1764-1769. (Pubitemid 26028664)
49. Janorkar AV, King KR, Megeed Z, Yarmush ML: Development of an in vitro cell culture model of hepatic steatosis using hepatocytederived reporter cells. Biotechnol Bioeng 2009; 105: 1466-1474.
50. Longo VD, Finch CE: Evolutionary medicine: from dwarf model systems to healthy centenarians? Science 2003; 299: 1342-1346. (Pubitemid 36254638)
51. Shimokawa I: Rodent models for the study of the role of growth hormone-insulin-like growth factor-1 or the insulin axis in aging and longevity: special reference to a transgenic dwarf rat strain and calorie restriction; in Nyberg FJ (ed): The Somatotrophic Axis in Brain Function. Burlington, Elsevier Academic, 2006, pp 173-184.
52. Kahn BB, Alquier T, Carling D, Hardie DG: AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 2005; 1: 15-25. (Pubitemid 43960587)
53. Pallottini V, Montanari L, Cavallini G, Bergamini E, Gori Z, Trentalance A: Mechanisms underlying the impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in aged rat liver. Mech Ageing Dev 2004; 125: 633-639. (Pubitemid 39371159)
54. Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME: Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor. Cell 1999; 96: 857-868. (Pubitemid 29165088)
55. Kops GJ, de Ruiter ND, de Vries-Smits AM, Powell DR, Bos JL, Burgering BM: Direct control of the Forkhead transcription factor AFX by protein kinase B. Nature 1999; 398: 630-634. (Pubitemid 29183692)
56. Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, Tissenbaum HA, Ruvkun G: The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 1997; 389: 994-999. (Pubitemid 27485694)
57. Cheung PCF, Salt IP, Davies SP, Hardie DG, Carling D: Characterization of AMP-activated protein kinase γ -subunit isoforms and their role in AMP binding. Biochem J 2000; 346: 659-669. (Pubitemid 30171026)
58. Guarente L, Kenyon C: Genetic pathways that regulate ageing in model organisms. Nature 2000; 408: 255-262.
59. Imai S, Armstrong CM, Kaeberlein M, Guarente L: Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase. Nature 2000; 403: 795-800. (Pubitemid 30111843)
60. Brachmann CB, Sherman JM, Devine SE, Cameron EE, Pillus L, Boeke JD: The Sir2 gene family, conserved from bacteria to humans, functions in silencing, cell-cycle progression, and chromosome stability. Genes Dev 1995; 9: 2888-2902.
61. Afshar G, Murnane JP: Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2. Gene 1999; 234: 162-166.
62. Gottlieb S, Esposito RE: A new role for a yeast transcriptional silencer gene, Sir2, in regulation of recombination in ribosomal DNA. Cell 1989; 56: 771-776. (Pubitemid 19082512)
63. Shore D, Squire M, Nasmyth KA: Characterization of 2 genes required for the positioneffect control of yeast mating-type genes. EMBO J 1984; 3: 2817-2823.
64. Kaeberlein M, McVey M, Guarente L: The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes Dev 1999; 13: 2570-2580. (Pubitemid 29489648)
65. Tissenbaum HA, Guarente L: Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 2001; 410: 227-230. (Pubitemid 32216597)
66. Wang Y, Oh SW, Deplancke B, Luo J, Walhout AJM, Tissenbaum HA: C. elegans 14-3- 3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO. Mech Ageing Dev 2006; 127: 741-747. (Pubitemid 44188819)
67. Rogina B, Helfand SL: Sir2 mediates longevity in the fly through a pathway related to calorie restriction. Proc Natl Acad Sci USA 2004; 101: 15998-16003. (Pubitemid 39507916)
68. Guarente L: Sirtuins as potential targets for metabolic syndrome. Nature 2006; 444: 868-874. (Pubitemid 46024994)
69. Wullschleger S, Loewith R, Hall MN: TOR signaling in growth and metabolism. Cell 2006; 127: 5-9.
70. Inoki K, Guan KL: Complexity of the TOR signaling network. Trends Cell Biol 2006; 16: 206-212.
71. Sarbassov DD, Ali SM, Sabatini DM: Growing roles for the mTOR pathway. Curr Opin Cell Biol 2005; 17: 596-603. (Pubitemid 41540408)
72. Powers RW, Kaeberlein M, Caldwell SD, Kennedy BK, Fields S: Extension of chronological life span in yeast by decreased TOR pathway signaling. Genes Dev 2006; 20: 174-184. (Pubitemid 43112936)
73. Min KJ, Tatar M: Restriction of amino acids extends lifespan in Drosophila melanogaster. Mech Ageing Dev 2006; 127: 643-646. (Pubitemid 43744514)
74. Miller RA, Buehner G, Chang Y, Harper JM, Sigler R, Smith-Wheelock M: Methioninedeficient diet extends mouse lifespan, slows immune and lens aging, alters glucose, T4, IGF-I and insulin levels, and increases hepatocyte MIF levels and stress resistance. Aging Cell 2005; 4: 119-125. (Pubitemid 41602745)
75. Zimmerman JA, Malloy V, Krajcik R, Orentreich N: Nutritional control of aging. Exp Gerontol 2003; 38: 47-52. (Pubitemid 36113261)
76. Kahn BB, Alquier T, Carling D, Hardie DG: AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 2005; 1: 15-25. (Pubitemid 43960587)
77. Inoki K, Guan KL: Complexity of the TOR signaling network. Trends Cell Biol 2006; 16: 206-212.
78. Shaw RJ, Bardeesy N, Manning BD, Lopez L, Kasmatka M, DePinho RA, Cantley LC: The LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell 2004; 6: 91-99. (Pubitemid 38903165)
79. Bishop NA, Guarente L: Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 2007; 447: 545-549. (Pubitemid 46868049)
80. Panowski SH, Wolff S, Aguilaniu H, Durieux J, Dillin A: PHA-4/Foxa mediates dietrestriction- induced longevity of C. elegans. Nature 2007; 447: 550-555. (Pubitemid 46868041)
81. Mango SE, Lambie EJ, Kimble J: The pha-4 gene is required to generate the pharyngeal primordium of Caenorhabditis elegans. Development 1994; 120: 3019-3031. (Pubitemid 24312068)
82. Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang RA: A C. elegans mutant that lives twice as long as wild type. Nature 1993; 366: 461-464. (Pubitemid 24013878)
83. Brenkman AB, Burgering BMT: Live longer through PHAsting. Cell Metab 2007; 5: 407-409. (Pubitemid 46825501)
84. Wolfrum C, Asilmaz E, Luca E, Friedman JM, Stoffel M: Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes. Nature 2004; 432: 1027-1032. (Pubitemid 40052233)
85. Walker AK, See R, Batchelder C, Kophengnavong T, Gronniger JT, Shi Y, Blackwell TK: A conserved transcription motif suggesting functional parallels between Caenorhabditis elegans SKN-1 and Cap'n'Collar-related basic leucine zipper proteins. J Biol Chem 2000; 275: 22166-22171. (Pubitemid 30621797)
86. Hayes JD, McMahon M: Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention. Cancer Lett 2001; 174: 103-113. (Pubitemid 33026113)
87. Wolf CR: Chemoprevention: increased potential to bear fruit. Proc Natl Acad Sci USA 2001; 98: 2941-2943. (Pubitemid 32220775)
88. Bowerman B, Eaton BA, Priess JR: Skn-1, a maternally expressed gene required to specify the fate of ventral blastomeres in the early C. elegans embryo. Cell 1992; 68: 1061-1075.
89. Everitt AV, le Couteur DG: Life extension by calorie restriction in humans. Ann NY Acad Sci 2007; 1114: 428-433. (Pubitemid 350070374)
90. Ingram DK, Roth GS, Lane MA, Ottinger MA, Zou S, Cabo R, Mattison JA: The potential for dietary restriction to increase longevity in humans: extrapolation from monkey studies. Biogerontology 2006; 7: 143-148. (Pubitemid 44151622)
91. Fontana L, Weiss EP, Villareal DT, Klein S, Holloszy JO: Long-term effects of calorie or protein restriction on serum IGF-1 and IGFBP-3 concentration in humans. Aging Cell 2008; 7: 681-687.