CYP1A1 induction in the colon by serum: Involvement of the PPARα pathway and evidence for a new specific human PPREα site

PLoS ONE

Volumn 6, Issue 1, 2011, Pages

  Villard, Pierre Henri ^a,b   Barlesif, Fabrice ^c   Armand, Martine ^a,b   Dao, Thi Mai Anh ^a,b   Pascussi, Jean Marc ^d   Fouchier, Francis ^a,b   Champion, Serge ^a,b   Dufour, Claire ^e   Giniès, Christian ^e   Khalil, Ayman ^a,b   Amiot, Marie Josephe ^a,b   Barra, Yves ^a,b   Seree, Eric ^a,b  

^a INSERM   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c ASSISTANCE PUBLIQUE HÔPITAUX DE MARSEILLE   (France)

^d UNIVERSITÉ DE PERPIGNAN   (France)

^e UNIVERSITY OF AVIGNON   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1A1; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; ALDEHYDE; N HEXANAL; N-HEXANAL;

ARTICLE; CANCER CELL CULTURE; COLON; CONTROLLED STUDY; ENZYME ASSAY; GEL MOBILITY SHIFT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; HYDROPHOBICITY; IN VITRO STUDY; LIPID COMPOSITION; MASS FRAGMENTOGRAPHY; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SITE DIRECTED MUTAGENESIS; SOLID PHASE MICROEXTRACTION; BINDING SITE; BIOSYNTHESIS; CHEMISTRY; DNA RESPONSIVE ELEMENT; DRUG EFFECT; GENETICS; METABOLISM; PROMOTER REGION; SERUM; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ALDEHYDES; BINDING SITES; COLON; CYTOCHROME P-450 CYP1A1; HUMANS; PPAR ALPHA; PROMOTER REGIONS, GENETIC; RESPONSE ELEMENTS; SERUM; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 79551615746     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0014629     Document Type: Article

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