Early blood glucose profile and neurodevelopmental outcome at two years in neonatal hypoxic-ischaemic encephalopathy

BMC Pediatrics

Volumn 11, Issue , 2011, Pages

  Nadeem, Montasser ^a   Murray, Deirdre M ^b   Boylan, Geraldine B ^b   Dempsey, Eugene M ^a   Ryan, Cornelius A ^a  

^a Irish Centre for Fetal and Neonatal Translational Research   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; BIOLOGICAL MARKER;

ARTICLE; BLOOD GLUCOSE MONITORING; BLOOD SAMPLING; BRAIN ISCHEMIA; CHILD; CLINICAL TRIAL; COHORT ANALYSIS; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERGLYCEMIA; HYPOGLYCEMIA; INFANT; MAJOR CLINICAL STUDY; MALE; NERVE CELL DIFFERENTIATION; NEWBORN; OUTCOME ASSESSMENT; PRESCHOOL CHILD; PROSPECTIVE STUDY; TERM BIRTH; TREATMENT OUTCOME; BIRTH WEIGHT; BLOOD; CHRONIC BRAIN DISEASE; FOLLOW UP; GESTATIONAL AGE; HYPOXIC ISCHEMIC ENCEPHALOPATHY; INDUCED HYPOTHERMIA; NEWBORN HYPOXIA; RETROSPECTIVE STUDY; TIME;

ASPHYXIA NEONATORUM; BIOLOGICAL MARKERS; BIRTH WEIGHT; BLOOD GLUCOSE; BRAIN DAMAGE, CHRONIC; FEMALE; FOLLOW-UP STUDIES; GESTATIONAL AGE; HUMANS; HYPERGLYCEMIA; HYPOGLYCEMIA; HYPOTHERMIA, INDUCED; HYPOXIA-ISCHEMIA, BRAIN; INFANT, NEWBORN; MALE; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME;

EID: 79551610668     PISSN: None     EISSN: 14712431     Source Type: Journal    
DOI: 10.1186/1471-2431-11-10     Document Type: Article

References (30)

1. Vannucci RC. Hypoxic-ischemic encephalopathy. Am J Perinatol 2000, 17:113-20. 10.1055/s-2000-9293, 11012134.
2. Glass HC, Ferriero DM. Treatment of hypoxic-ischemic encephalopathy in newborns. Curr Treat Options Neurol 2007, 6:414-23.
3. Caraballo RH, Sakr D, Mozzi M, et al. Symptomatic occipital lobe epilepsy following neonatal hypoglycemia. Pediatr Neurol 2004, 31:24-9. 10.1016/j.pediatrneurol.2003.12.008, 15246488.
4. Burns CM, Rutherford MA, Boardman JP, et al. Patterns of cerebral injury and neurodevelopmental outcomes after symptomatic neonatal hypoglycemia. Pediatrics 2008, 122:65-74. 10.1542/peds.2007-2822, 18595988.
5. Lucas A, Morley R, Cole TJ. Adverse neurodevelopmental outcome of moderate neonatal hypoglycaemia. BMJ 1988, 297:1304-8. 10.1136/bmj.297.6659.1304, 1834933, 2462455.
6. Hawdon JM. Hypoglycaemia and the neonatal brain. Eur J Pediatr 1999, 158(Suppl 1):S9-S12. 10.1007/PL00014319, 10592092.
7. Rozance PJ, Hay WW. Hypoglycemia in newborn infants: Features associated with adverse outcomes. Biol Neonate 2006, 90(2):74-86. 10.1159/000091948, 16534190.
8. Basu P, Som S, Choudhuri N, et al. Contribution of the blood glucose level in perinatal asphyxia. Eur J Pediatr 2009, 168(7):833-8. 10.1007/s00431-008-0844-5, 18843505.
9. Salhab WA, Wyckoff MH, Laptook AR, et al. Initial hypoglycemia and neonatal brain injury in term infants with severe fetal acidemia. Pediatrics 2004, 114:361-6. 10.1542/peds.114.2.361, 15286217.
10. Park TS, Gonzales ER, Shah AR, et al. Hypoglycemia selectively abolishes hypoxic reactivity of pial arterioles in piglets: role of adenosine. Am J Physiol 1995, 268:H871-8.
11. McGowan JE, Chen L, Gao D, et al. Increased mitochondrial reactive oxygen species production in newborn brain during hypoglycemia. Neurosci Lett 2006, 399(1-2):111-4. 10.1016/j.neulet.2006.01.034, 16490311.
12. Auer RN. Hypoglycemic brain damage. Metab Brain Dis 2004, 19(3-4):169-75. 10.1023/B:MEBR.0000043967.78763.5b, 15554413.
13. Blanco CL, Baillargeon JG, Morrison RL, et al. Hyperglycemia in extremely low birth weight infants in a predominantly Hispanic population and related morbidities. J Perinatol 2006, 26:737-41. 10.1038/sj.jp.7211594, 16929343.
14. Kao LS, Morris BH, Lally KP, et al. Hyperglycemia and morbidity and mortality in extremely low birth weight infants. J Perinatol 2006, 26:730-6. 10.1038/sj.jp.7211593, 16929344.
15. Hays SP, Smith EO, Sunehag AL. Hyperglycemia is a risk factor for early death and morbidity in extremely low birth-weight infants. Pediatrics 2006, 118:1811-8. 10.1542/peds.2006-0628, 17079549.
16. Klein GW, Hojsak JM, Schmeidler J, et al. Hyperglycemia and outcome in the pediatric intensive care unit. J Pediatr 2008, 153:379-84. 10.1016/j.jpeds.2008.04.012, 18534209.
17. Lodha R, Bhutia TD, Kabra SK, et al. Day 1 blood glucose and outcome in critically ill children. Indian Pediatr 2009, 46:809-10.
18. Alvarez-Sabín J, Molina CA, Ribó M, et al. Impact of admission hyperglycemia on stroke outcome after thrombolysis: risk stratification in relation to time to reperfusion. Stroke 2004, 35:2493-8.
19. Collins JW, Hoppe M, Brown K, et al. A controlled trial of insulin infusion and parenteral nutrition in extremely low birth weight infants with glucose intolerance. J Pediatr 1991, 118(6):921-7. 10.1016/S0022-3476(05)82212-7, 1904090.
20. Vlasselaers D, Milants I, Desmet L, et al. Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study. Lancet 2009, 373(9663):547-56. 10.1016/S0140-6736(09)60044-1, 19176240.
21. Park WS, Chang YS, Lee M. Effects of hyperglycemia or hypoglycemia on brain cell membrane function and energy metabolism during the immediate reoxygenation-reperfusion period after acute transient global hypoxia-ischemia in the newborn piglet. Brain Res 2001, 901:102-8. 10.1016/S0006-8993(01)02295-8, 11368956.
22. Blomstrand S, Hrbek A, Karlsson K, et al. Does glucose administration affect the cerebral response to fetal asphyxia?. Acta Obstet Gynecol Scand 1984, 63(4):345-53. 10.3109/00016348409155529, 6430023.
23. Lin B, Ginsberg MD, Busto R. Hyperglycemic exacerbation of neuronal damage following forebrain ischemia: microglial, astrocytic and endothelial alterations. Acta Neuropathol 1998, 96(6):610-20. 10.1007/s004010050942, 9845291.
24. Barnett AL, Guzzetta A, Mercuri E, et al. Can the Griffiths scales predict neuromotor and perceptualmotor impairment in term infants with neonatal encephalopathy?. Arch Dis Child 2004, 89:637-643. 10.1136/adc.2002.019349, 1719998, 15210495.
25. Cornblath M, Schwartz R. Outcome of neonatal hypoglycaemia. Complete data are needed. BMJ 1999, 318:194-5. Reply by Lucas A, Morley R. BMJ 1999; 318:195, 1114678, 9888932.
26. Kinnala A, Rikalainen H, Lapinleimu H, et al. Cerebral magnetic resonance imaging and ultrasonography findings after neonatal hypoglycemia. Pediatrics 1999, 103:724-9. 10.1542/peds.103.4.724, 10103293.
27. Koh TH, Aynsley-Green A, Tarbit M, et al. Neural dysfunction during hypoglycaemia. Arch Dis Child 1988, 63:1353-8. 10.1136/adc.63.11.1353, 1779138, 3202642.
28. Brand PL, Molenaar NL, Kaaijk C, et al. Neurodevelopmental outcome of hypoglycaemia in healthy, large for gestational age, term newborns. Arch Dis Child 2005, 90:78-81. 10.1136/adc.2003.039412, 1720084, 15613521.
29. Simpson IA, Carruthers A, Vannucci SJ. Supply and demand in cerebral energy metabolism: the role of nutrient transporters. J Cereb Blood Flow Metab 2007, 27(11):1766-91. 10.1038/sj.jcbfm.9600521, 2094104, 17579656.
30. LeBlanc MH, Huang M, Patel D, Smith EE, Devidas M. Glucose given after hypoxic ischemia does not affect brain injury in piglets. Stroke 1994, 25(7):1443-7.