Synthesis of a novel restricted access chiral stationary phase based on atom transfer radical polymerization and click chemistry for the analysis of chiral drugs in biological matrices

Journal of Chromatography A

Volumn 1218, Issue 9, 2011, Pages 1310-1313

  Wang, Huaisong ^a   Jiang, Ping ^a   Zhang, Min ^a   Dong, Xiangchao ^a  

^a NANKAI UNIVERSITY   (China)

Author keywords

CD; Atom transfer radical polymerization (ATRP); Biological samples; Enantioseparation; Restricted access material

Indexed keywords

ATOM TRANSFER RADICAL POLYMERIZATION (ATRP); BI-LAYER; BIOLOGICAL MATRIXES; BIOLOGICAL SAMPLES; CHIRAL COMPOUNDS; CHIRAL DISCRIMINATION; CHIRAL DRUGS; CHIRAL STATIONARY PHASE; CLICK CHEMISTRY; ENANTIOSEPARATIONS; EPOXY GROUP; INNER LAYER; POLY(GLYCIDYL METHACRYLATE); POROUS SILICA; RESTRICTED ACCESS MATERIALS; SECOND ATRP; SURFACE-INITIATED ATRP;

ACRYLIC MONOMERS; ATOMS; BIOLOGICAL MATERIALS; CHEMICAL ANALYSIS; DIRECT INJECTION; DRIERS (MATERIALS); FREE RADICAL REACTIONS; GRAFTING (CHEMICAL); POLYMERIZATION; POLYMERS; SILICA; SILICA GEL; SYNTHESIS (CHEMICAL);

ATOM TRANSFER RADICAL POLYMERIZATION;

AMINOGLUTETHIMIDE; AZIDE; BENZOIN; BETA CYCLODEXTRIN; CHLORPHENIRAMINE; CHLORTALIDONE; IBUPROFEN; MANDELIC ACID; METHACRYLIC ACID DERIVATIVE; POLY(2 METHYL 3 BUTYN 3 OL METHACRYLATE); POLY(GLYCIDYL METHACRYLATE); SILICON DIOXIDE; UNCLASSIFIED DRUG;

ARTICLE; ATOM TRANSFER RADICAL POLYMERIZATION; CHIRALITY; CONTROLLED STUDY; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; HYDROPHILICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; SEPARATION TECHNIQUE; SYNTHESIS;

AZIDES; BETA-CYCLODEXTRINS; CLICK CHEMISTRY; HUMANS; PHARMACEUTICAL PREPARATIONS; POLYMERIZATION; POROSITY; SILICA GEL; STEREOISOMERISM;

EID: 79551605311     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chroma.2011.01.005     Document Type: Article

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