Valproate-induced reversible 'Parkinsonism plus' syndrome

Journal, Indian Academy of Clinical Medicine

Volumn 11, Issue 3, 2010, Pages 235-238

  Khwaja, Geeta A ^b   Ranjan, R ^a   Gupta, M ^b   Chowdhry, D ^b   Hirve, M ^a  

^a G B PANT HOSPITAL   (India)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BROMOCRIPTINE; VALPROIC ACID;

ADULT; ARTICLE; BRADYKINESIA; CASE REPORT; DRUG BLOOD LEVEL; DYSPHAGIA; DYSPHONIA; FEMALE; FOCAL EPILEPSY; GRANULOMA; HAND TREMOR; HUMAN; HYPERREFLEXIA; MUSCLE RIGIDITY; PARKINSONISM; PHYSIOTHERAPY; SHY DRAGER SYNDROME; SOMNOLENCE;

EID: 79551595202     PISSN: 09723560     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Hyman NM, Dennis PD, Sinclair KG. Tremor due to sodium valproate. Neurology 1979; 29: 1177-80.
2. Karas BJ, Wilder BJ, Hammond EJ et al. Valproate tremors. Neurology 1982; 32: 428-32.
3. Onofrj M, Thomas A, Paci C. Reversible Parkinsonism induced by prolonged treatment with valproate. J Neurol 1998; 245 (12): 794-6.
4. Karas BJ, Wilder BJ, Hammond EJ et al. Treatment of valproate tremors. Neurology 1983; 33: 1380-82.
5. Shorvon S. The antiepelileptic drugs. Hand book of epilepsy treatment. 2nd edition, Blackwell Publishing, Chapter 3, Pg 114-210.
6. Lautin A, Stanely M, Angrist B et al. Extrapyramidal syndrome with sodium valproate. Br Med J 1979; 2: 1035-6.
7. Park Matsumoto YC, Tazawa T. Valproate-induced Parkisnsonism. No To Shinki 1998; 50 (1): 81-4.
8. Schreur L, Middeljans-Tijssen CW, Hengstman GJ, Olde Rikkert MG. Cognitive impairment and Parkinsonisms due to use of sodium valproate. Tijdschr Gertontol Geriatr 2009; 40 (1): 29-33.
9. Ristic AJ, Vojvodic N, Jankovi S. The frequency of reversible Parkinsonism and cognitive decline associated with valproate treatment: A study of 364 patients with different types of epilepsy. Epliepsia 2006; 47 (12): 2183-5.
10. Jamora D, Lim SH, Lim SH et al. Valproate-induced Parkinsonism in epilepsy patients. Movement Disorders 2007; 22 (1): 130-32.
11. Tan LC, Venketasubramanjan N, Hong CY et al. Prevalence of Parkinson disease in Singapore: Chinese vs. Malays Indians. Neurology 2004; 62: 1999-2004.
12. Easterford K, Clough P, Kellett M et al. Reversible Parkinsonism with normal β-CIT-SPECT in patients exposed to sodium valproate. Neurology 2004; 62: 1435-7.
13. Schrag A, Quinn N. Cross-sectional prevalence survey of idiopathic Parkinson's disease and Parkinsonism in London. Medical Journal 2000; 321: 21-2.
14. Armon C, Shin C, Miller P et al. Reversible Parkinsonism and cognitive impairment with chronic valproate use. Neurology 1996; 47: 626-35.
15. Masmoudi K, Gras-Champel V, Masson H, Andrejak M. Parkinsonism and/or cognitive impairment with valproic acid therapy: a report of ten cases. Pharmacosychiatry 2006; 39: 9-12.
16. Alvarez-Gomez MJ, Vaamonde J, Narbona J et al. Parkinsonism syndrome in childhood after sodium valproate administration. Neuropharmacol 1993; 16: 451-5.
17. Sasso E, Delsoldato S, Negrotti A, Mancia D. Reversible valproate-induced extrapyramidal disorders. Epilepsia 1994; 35: 391-3.
18. Froomes PR, Stewart MR. A reversible Parkinsonian syndrome and hepatotoxicity following addition of carbamazepine to sodium valproate. Aust NZJ Med 1994; 24: 413-4.
19. Shill HA, Fife TD. Valproic acid toxicity mimicking multiple system atrophy. Neurology 2000; 55: 1936-7.
20. Chakravarty A. Movement disorders induced by antiepileptic drugs. Unsung topics in neurological practice edited by A. chakravarty. A publication of Journal of Association of neuroscientists of eastern India. Chapter 10, Pg. 109-124.
21. Lancman ME, Asconape JJ, Walker F. Acetazolamide appears effective in the management of valproateinduced tremor. Mov Disord 1994; 9: 369.
22. Segura-Bruna N, Rodriguez-Campello A, Puente V, Roquer J. Valproate-induced hyperammoneimic encephalopathy. Acta Neurol Scand 2006; 114 (1): 1-7.
23. Wadzinski J, Franks R, Roane D, Bayard M. Valproateassociated hyperammonaemic encephalopathy. The Journal of the American Board of Family Medicine 2007; 20 (5): 499-502.
24. Guin DS, Biswas S, Saha K et al. A case of nonhyperammonaemic valproate-induced encephalopathy. Neurology Asia 2006; 135-7.