메뉴 건너뛰기




Volumn 17, Issue 1, 2011, Pages 49-52

CNS drug development: Part III: Future directions

Author keywords

Alzheimer's disease; central nervous system drugs; drug development; drug discovery; drug targets; human genome project

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; CENTRAL NERVOUS SYSTEM AGENTS; CHOLINESTERASE INHIBITOR; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR;

EID: 79551542377     PISSN: 15274160     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pra.0000393844.48593.82     Document Type: Article
Times cited : (15)

References (20)
  • 1
    • 77957596338 scopus 로고    scopus 로고
    • CNS drug development: Part I: The early period of CNS drugs
    • Preskorn SH. CNS drug development: Part I: The early period of CNS drugs. J Psychiatr Pract 2010;16:334-39.
    • (2010) J. Psychiatr. Pract. , vol.16 , pp. 334-339
    • Preskorn, S.H.1
  • 2
    • 78650358004 scopus 로고    scopus 로고
    • CNS drug development: Part II: Advances from the 1960s to the 1990s
    • Preskorn SH. CNS drug development: Part II: Advances from the 1960s to the 1990s. J Psychiatr Pract 2010;16:413-15.
    • (2010) J. Psychiatr. Pract. , vol.16 , pp. 413-415
    • Preskorn, S.H.1
  • 3
    • 0343262714 scopus 로고    scopus 로고
    • Choosing anticancer drug targets in the postgenomic era
    • Kaelin WG, Jr. Choosing anticancer drug targets in the postgenomic era. J Clin Invest 1999;104:1503-6.
    • (1999) J. Clin. Invest. , vol.104 , pp. 1503-1506
    • Kaelin Jr., W.G.1
  • 4
    • 79551554999 scopus 로고    scopus 로고
    • Pharmacogenomics: Methods and protocols
    • Lai CW. Pharmacogenomics: Methods and protocols. Br J Cancer 2006;94:1553.
    • (2006) Br. J. Cancer , vol.94 , pp. 1553
    • Lai, C.W.1
  • 6
    • 79551556506 scopus 로고    scopus 로고
    • Egon Zehnder International, Available at
    • Egon Zehnder International. Big pharma's new leadership models: Making them work. 2008 (Available at www.egonzehnder.com/global/download/ issue1bigpharma.pdf.
    • (2008) Big Pharma's New Leadership Models: Making Them Work
  • 7
    • 79551562947 scopus 로고    scopus 로고
    • Rockville, MD: National Institute of Mental Health Director's Blog. March 30, 2010 available at, accessed September 3, 2010
    • Insell T. Who will develop the next generation of medications for mental illness? Rockville, MD: National Institute of Mental Health Director's Blog. March 30, 2010 (available at www.nimh.nih.gov/about/director/2010/who-will- developthe-next-generation-of-medications-for-mentalillness.shtml, accessed September 3, 2010)
    • Who Will Develop the Next Generation of Medications for Mental illness?
    • Insell, T.1
  • 8
    • 77952571701 scopus 로고    scopus 로고
    • The perfect storm: CNS drug development in trouble
    • available at, accessed September 3, 2010
    • Nierenberg AA. The perfect storm: CNS drug development in trouble. CNS Spectr 2010;15:282-3 (available at www.cnsspectrums.com/aspx/article-pf.aspx? articleid=2625, accessed September 3, 2010).
    • (2010) CNS Spectr. , vol.15 , pp. 282-283
    • Nierenberg, A.A.1
  • 9
    • 57649140590 scopus 로고    scopus 로고
    • Removing obstacles in neuroscience drug discovery: The future path for animal models
    • Markou A, Chiamulera C, Geyer MA, et al. Removing obstacles in neuroscience drug discovery: The future path for animal models. Neuropsychopharmacology 2009;34:74-89.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 74-89
    • Markou, A.1    Chiamulera, C.2    Geyer, M.A.3
  • 10
    • 48749125741 scopus 로고    scopus 로고
    • Alzheimer's disease drug development in 2008 and beyond: Problems and opportunities
    • Becker RE, Greig, NH. Alzheimer's disease drug development in 2008 and beyond: Problems and opportunities. Curr Alzheimer Res 2008;5:346-57.
    • (2008) Curr. Alzheimer Res. , vol.5 , pp. 346-357
    • Becker, R.E.1    Greig, N.H.2
  • 11
    • 67650088426 scopus 로고    scopus 로고
    • The basics of preclinical drug development for neurodegenerative disease indications
    • Steinmetz KL, Spack EG. The basics of preclinical drug development for neurodegenerative disease indications. BMC Neurol 2009;9(suppl 1):S2.
    • (2009) BMC Neurol. , vol.9 , Issue.1 SUPPL.
    • Steinmetz, K.L.1    Spack, E.G.2
  • 12
    • 0036124107 scopus 로고    scopus 로고
    • CYP2D6 allele frequency in European caucasians, asians, Africans and their descendants
    • Bradford LD. CYP2D6 allele frequency in European Caucasians, Asians, Africans and their descendants. Pharmacogenomics 2002;3, 229-43.
    • (2002) Pharmacogenomics , vol.3 , pp. 229-243
    • Bradford, L.D.1
  • 13
    • 54249154592 scopus 로고    scopus 로고
    • Controversies in Alzheimer's disease drug development
    • Cummings JL. Controversies in Alzheimer's disease drug development. Int Rev Psychiatry 2008;20:389-95.
    • (2008) Int. Rev. Psychiatry , vol.20 , pp. 389-395
    • Cummings, J.L.1
  • 14
    • 57649136762 scopus 로고    scopus 로고
    • Risk in CNS drug discovery: Focus on treatment of Alzheimer's disease
    • Pritchard JF. Risk in CNS drug discovery: focus on treatment of Alzheimer's disease. BMC Neurosci 2008;9(suppl 3):S1.
    • (2008) BMC Neurosci. , vol.9 , Issue.3 SUPPL.
    • Pritchard, J.F.1
  • 16
    • 0000293742 scopus 로고    scopus 로고
    • Über eine eigenartige Erkangkung der Hirnrinde
    • Originally published in
    • Alzheimer A. Über eine eigenartige Erkangkung der Hirnrinde [About a peculiar disease of the cerebral cortex]. Originally published in Allgemeine Zeitschr Psychisch-Gerichtliche Medizin 2007;64:146-148).
    • (2007) Allgemeine Zeitschr Psychisch-gerichtliche Medizin , vol.64 , pp. 146-148
    • Alzheimer, A.1
  • 18
    • 0032008710 scopus 로고    scopus 로고
    • Histopathology and APOE genotype of the first Alzheimer disease patient
    • Auguste D. Graeber MB, Kösel S, et al. Histopathology and APOE genotype of the first Alzheimer disease patient. Neurogenetics 1998;1:223-8.
    • (1998) Neurogenetics , vol.1 , pp. 223-228
    • Auguste, D.1    Graeber, M.B.2    Kösel, S.3
  • 19
    • 33750047455 scopus 로고    scopus 로고
    • Alois Alzheimer and Alzheimer's disease: A centennial perspective
    • Small DH, Cappai R. Alois Alzheimer and Alzheimer's disease: A centennial perspective. J Neurochem 2006;99:708-10.
    • (2006) J. Neurochem. , vol.99 , pp. 708-710
    • Small, D.H.1    Cappai, R.2
  • 20
    • 0017618768 scopus 로고
    • Depression: A new animal model sensitive to antidepressant treatments
    • Porsolt RD, Le Pichon M, Jalfre M. Depression: A new animal model sensitive to antidepressant treatments. Nature 1977;266:730-2.
    • (1977) Nature , vol.266 , pp. 730-732
    • Porsolt, R.D.1    Le Pichon, M.2    Jalfre, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.