Increased Th17 cells in coronary artery disease are associated with neutrophilic inflammation

Scandinavian Cardiovascular Journal

Volumn 45, Issue 1, 2011, Pages 54-61

  Wang, Zikuan ^a   Lee, Jun ^a   Zhang, Ye ^a   Wang, Hongtao ^a   Liu, Xiongtao ^a   Shang, Fujun ^a   Zheng, Qiangsun ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

atherosclerosis; infl ammation; neutrophil; Th17

Indexed keywords

ACETYLSALICYLIC ACID; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 17; INTERLEUKIN 8; MESSENGER RNA;

ACUTE CORONARY SYNDROME; ADULT; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CYTOKINE RELEASE; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOPATHOGENESIS; INFLAMMATION; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL COUNT; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STABLE ANGINA PECTORIS; TH17 CELL;

ADULT; ATHEROSCLEROSIS; CASE-CONTROL STUDIES; CELL COUNT; CORONARY ARTERY DISEASE; FEMALE; HUMANS; INFLAMMATION; INTERLEUKIN-17; INTERLEUKIN-8; MALE; MIDDLE AGED; NEUTROPHILS; RNA, MESSENGER; TH17 CELLS;

EID: 79551542044     PISSN: 14017431     EISSN: 16512006     Source Type: Journal    
DOI: 10.3109/14017431.2010.491123     Document Type: Article

References (28)

1. Robertson AK, Hansson GK. T cells in atherogenesis: For better or for worse? Arterioscler Thromb Vasc Biol. 2006;26:2421-32.
2. Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, et al. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infi ltrating T cells and act synergistically on vascular smooth muscle cells. Circulation. 2009;119:1424-32.
3. Park H, Li Z, Yang XO, Chang SH, Nurieva R, Wang YH, et al. A distinct lineage of CD4 T cells regulates tissue infl ammation by producing interleukin 17. Nat Immunol. 2005; 6:1133-41.
4. Iwakura Y, Nakae S, Saijo S, Ishigame H. The roles of IL-17A in infl ammatory immune responses and host defense against pathogens. Immunol Rev. 2008;226:57-79.
5. Kolls JK, Linden A. Interleukin-17 family members and infl ammation. Immunity. 2004;21:467-76.
6. Naruko T, Ueda M, Haze K, van der Wal AC, van der Loos CM, Itoh A, et al. Neutrophil infi ltration of culprit lesions in acute coronary syndromes. Circulation. 2002;106:2894-900.
7. Nijm J, Wikby A, Tompa A, Olsson AG, Jonasson L. Circulating levels of proinfl ammatory cytokines and neutrophilplatelet aggregates in patients with coronary artery disease. Am J Cardiol. 2005;95:452-6.
8. Paulsson J, Dadfar E, Held C, Jacobson SH, Lundahl J. Activation of peripheral and in vivo transmigrated neutrophils in patients with stable coronary artery disease. Atherosclerosis. 2007;192:328-34.
9. Bullens DM, Truyen E, Coteur L, Dilissen E, Hellings PW, Dupont LJ, et al. IL-17 mRNA in sputum of asthmatic patients: Linking T cell driven infl ammation and granulocytic infl ux? Respir Res. 2006;7:135.
10. Zhang JY, Zhang Z, Lin F, Zou ZS, Xu RN, Jin L, et al. Interleukin-17-producing CD4T cells increase with severity of liver damage in patients with chronic hepatitis B. Hepatology. 2010;51:81-91.
11. Maek ANW, Buranapraditkun S, Klaewsongkram J, Ruxrungtham K. Increased interleukin-17 production both in helper T cell subset Th17 and CD4-negative T cells in human immunodefi ciency virus infection. Viral Immunol. 2007;20:66-75.
12. Vanaudenaerde BM, Dupont LJ, Wuyts WA, Verbeken EK, Meyts I, Bullens DM, et al. The role of interleukin-17 during acute rejection after lung transplantation. Eur Respir J. 2006;27:779-87.
13. Wei X, Jia ZS, Lian JQ, Zhang Y, Li J, Ma L, et al. Inhibition of hepatitis C virus infection by interferon-gamma through downregulating Claudin-1. J Interferon Cytokine Res. 2009.
14. Patel TN, Shishehbor MH, Bhatt DL. A review of high-dose statin therapy: Targeting cholesterol and infl ammation in atherosclerosis. Eur Heart J. 2007;28:664-72.
15. Khan Q, Mehta JL. Relevance of platelet-independent effects of aspirin to its salutary effect in atherosclerosis-related events. J Atheroscler Thromb. 2005;12:185-90.
16. Lee J, Zhuang Y, Wei X, Shang F, Wang J, Zhang Y, et al. Contributions of PD-1/PD-L1 pathway to interactions of myeloid DCs with T cells in atherosclerosis. J Mol Cell Cardiol. 2009;46:169-76.
17. Tedgui A, Mallat Z. Cytokines in atherosclerosis: Pathogenic and regulatory pathways. Physiol Rev. 2006;86:515-81.
18. Stockinger B, Veldhoen M, Martin B. Th17 T cells: Linking innate and adaptive immunity. Semin Immunol. 2007;19: 353-61.
19. Afzali B, Lombardi G, Lechler RI, Lord GM. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol. 2007;148:32-46.
20. Cheng X, Yu X, Ding YJ, Fu QQ, Xie JJ, Tang TT, et al. The Th17/Treg imbalance in patients with acute coronary syndrome. Clin Immunol. 2008;127:89-97.
21. Bettelli E, Korn T, Kuchroo VK. Th17: The third member of the effector T cell trilogy. Curr Opin Immunol. 2007;19:652-7.
22. Koshy PJ, Henderson N, Logan C, Life PF, Cawston TE, Rowan AD. Interleukin 17 induces cartilage collagen breakdown: Novel synergistic effects in combination with proinfl ammatory cytokines. Ann Rheum Dis. 2002;61:704-13.
23. Tartour E, Fossiez F, Joyeux I, Galinha A, Gey A, Claret E, et al. Interleukin 17, a T-cell-derived cytokine, promotes tumorigenicity of human cervical tumors in nude mice. Cancer Res. 1999;59:3698-704.
24. Weaver CT, Hatton RD, Mangan PR, Harrington LE. IL-17 family cytokines and the expanding diversity of effector T cell lineages. Annu Rev Immunol. 2007;25:821-52.
25. Linden A. Role of interleukin-17 and the neutrophil in asthma. Int Arch Allergy Immunol. 2001;126:179-84.
26. Boekholdt SM, Peters RJ, Hack CE, Day NE, Luben R, Bingham SA, et al. IL-8 plasma concentrations and the risk of future coronary artery disease in apparently healthy men and women: The EPIC-Norfolk prospective population study. Arterioscler Thromb Vasc Biol. 2004;24:1503-8.
27. Romuk E, Skrzep-Poloczek B, Wojciechowska C, Tomasik A, Birkner E, Wodniecki J, et al. Selectin-P and interleukin-8 plasma levels in coronary heart disease patients. Eur J Clin Invest. 2002;32:657-61.
28. Horne BD, Anderson JL, John JM, Weaver A, Bair TL, Jensen KR, et al. Which white blood cell subtypes predict increased cardiovascular risk? J Am Coll Cardiol. 2005;45:1638-43.