Rhinovirus infection induces expression of airway remodelling factors in vitro and in vivo

Respirology

Volumn 16, Issue 2, 2011, Pages 367-377

  Kuo, Curtis ^a   Lim, Sam ^a   King, Nicholas J C ^b   Bartlett, Nathan W ^c   Walton, Ross P ^c   Zhu, Jie ^c   Glanville, Nicholas ^c   Aniscenko, Julia ^c   Johnston, Sebastian L ^c   Burgess, Janette K ^a,d   Black, Judith L ^a,d   Oliver, Brian G ^a,d  

^a UNIVERSITY OF SYDNEY   (Australia)

^b Department of Microbiology and Infectious Diseases   (Australia)

^c WOOLCOCK INSTITUTE OF MEDICAL RESEARCH   (Australia)

^d NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

asthma; bronchial epithelium; extracellular matrix; fibroblast; rhinovirus

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 5; FIBRONECTIN; IMIQUIMOD; PERLECAN; POLYCYTIDYLIC ACID; POLYINOSINIC ACID; SCLEROPROTEIN; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 7; VASCULOTROPIN; VIRUS RNA;

ADULT; AIRWAY REMODELING; ANIMAL EXPERIMENT; ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS EPITHELIUM; LUNG HOMOGENATE; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RHINOVIRUS INFECTION;

AIRWAY REMODELING; AMINOQUINOLINES; ANIMALS; ASTHMA; BRONCHI; CELLS, CULTURED; COLLAGEN TYPE V; EXTRACELLULAR MATRIX; EXTRACELLULAR MATRIX PROTEINS; FEMALE; HUMANS; MICE; PICORNAVIRIDAE INFECTIONS; POLY I-C; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8;

EID: 79551539467     PISSN: 13237799     EISSN: 14401843     Source Type: Journal    
DOI: 10.1111/j.1440-1843.2010.01918.x     Document Type: Article

References (56)

1. Chetta A, Foresi A, Del Donno M, et al. Airways remodeling is a distinctive feature of asthma and is related to severity of disease. Chest 1997; 111: 852-7.
2. Boulet L, Belanger M, Carrier G,. Airway responsiveness and bronchial-wall thickness in asthma with or without fixed airflow obstruction. Am. J. Respir. Crit. Care Med. 1995; 152: 865-71.
3. Burgess JK,. The role of the extracellular matrix and specific growth factors in the regulation of inflammation and remodelling in asthma. Pharmacol. Ther. 2009; 122: 19-29.
4. Hoshino M, Nakamura Y, Sim JJ,. Expression of growth factors and remodelling of the airway wall in bronchial asthma. Thorax 1998; 53: 21-7.
5. Hirst SJ, Twort CH, Lee TH,. Differential effects of extracellular matrix proteins on human airway smooth muscle cell proliferation and phenotype. Am. J. Respir. Cell Mol. Biol. 2000; 23: 335-44.
6. Chan V, Burgess JK, Ratoff JC, et al. Extracellular matrix regulates enhanced eotaxin expression in asthmatic airway smooth muscle cells. Am. J. Respir. Crit. Care Med. 2006; 174: 379-85.
7. Slats AM, Janssen K, van Schadewijk A, et al. Expression of smooth muscle and extracellular matrix proteins in relation to airway function in asthma. J. Allergy Clin. Immunol. 2008; 121: 1196-202.
8. Jartti T, Lehtinen P, Vuorinen T, et al. Respiratory picornaviruses and respiratory syncytial virus as causative agents of acute expiratory wheezing in children. Emerg. Infect. Dis. 2004; 10: 1095-101.
9. Allander T, Jartti T, Gupta S, et al. Human bocavirus and acute wheezing in children. Clin. Infect. Dis. 2007; 44: 904-10.
10. Nicholson KG, Kent J, Ireland DC,. Respiratory viruses and exacerbations of asthma in adults. BMJ 1993; 307: 982-6.
11. Johnston SL, Pattemore PK, Sanderson G, et al. Community study of role of viral infections in exacerbations of asthma in 9-11 year old children. BMJ 1995; 310: 1225-9.
12. Papadopoulos NG, Bates PJ, Bardin PG, et al. Rhinoviruses infect the lower airways. J. Infect. Dis. 2000; 181: 1875-84.
13. Papadopoulos NG, Sanderson G, Hunter J, et al. Rhinoviruses replicate effectively at lower airway temperatures. J. Med. Virol. 1999; 58: 100-4.
14. Wos M, Sanak M, Soja J, et al. The presence of rhinovirus in lower airways of patients with bronchial asthma. Am. J. Respir. Crit. Care Med. 2008; 177: 1082-9.
15. Jartti T, Lehtinen P, Vuorinen T, et al. Persistence of rhinovirus and enterovirus RNA after acute respiratory illness in children. J. Med. Virol. 2004; 72: 695-9.
16. Jackson DJ, Gangnon RE, Evans MD, et al. Wheezing rhinovirus illnesses in early life predict asthma development in high-risk children. Am. J. Respir. Crit. Care Med. 2008; 178: 667-72.
17. Psarras S, Volonaki E, Skevaki CL, et al. Vascular endothelial growth factor-mediated induction of angiogenesis by human rhinoviruses. J. Allergy Clin. Immunol. 2006; 117: 291-7.
18. Wang JH, Kwon HJ, Jang YJ,. Rhinovirus enhances various bacterial adhesions to nasal epithelial cells simultaneously. Laryngoscope 2009; 119: 1406-11.
19. Sha Q, Truong-Tran AQ, Plitt JR, et al. Activation of airway epithelial cells by toll-like receptor agonists. Am. J. Respir. Cell Mol. Biol. 2004; 31: 358-64.
20. Uehara A, Fujimoto Y, Fukase K, et al. Various human epithelial cells express functional Toll-like receptors, NOD1 and NOD2 to produce anti-microbial peptides, but not proinflammatory cytokines. Mol. Immunol. 2007; 44: 3100-11.
21. Sugiura H, Ichikawa T, Koarai A, et al. Activation of Toll-like receptor 3 augments myofibroblast differentiation. Am. J. Respir. Cell Mol. Biol. 2009; 40: 654-62.
22. Kato H, Takeuchi O, Sato S, et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006; 441: 101-5.
23. Miller RL, Meng TC, Tomai MA,. The antiviral activity of Toll-like receptor 7 and 7/8 agonists. Drug News Perspect. 2008; 21: 69-87.
24. Bucchieri F, Puddicombe SM, Lordan JL, et al. Asthmatic bronchial epithelium is more susceptible to oxidant-induced apoptosis. Am. J. Respir. Cell Mol. Biol. 2002; 27: 179-85.
25. Roth M, Block LH,. Distinct effects of Broncho-Vaxom (OM-85 BV) on gp130 binding cytokines. Thorax 2000; 55: 678-84.
26. Oliver BG, Johnston SL, Baraket M, et al. Increased proinflammatory responses from asthmatic human airway smooth muscle cells in response to rhinovirus infection. Respir. Res. 2006; 7: 71.
27. Papi A, Johnston SL,. Rhinovirus infection induces expression of its own receptor intercellular adhesion molecule 1 (ICAM-1) via increased NF-kappaB-mediated transcription. J. Biol. Chem. 1999; 274: 9707-20.
28. Bartlett NW, Walton RP, Edwards MR, et al. Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation. Nat. Med. 2008; 14: 199-204.
29. Johnson PR, Black JL, Carlin S, et al. The production of extracellular matrix proteins by human passively sensitized airway smooth-muscle cells in culture: the effect of beclomethasone. Am. J. Respir. Crit. Care Med. 2000; 162: 2145-51.
30. Burgess JK, Johnson PR, Ge Q, et al. Expression of connective tissue growth factor in asthmatic airway smooth muscle cells. Am. J. Respir. Crit. Care Med. 2003; 167: 71-7.
31. Hewson CA, Jardine A, Edwards MR, et al. Toll-like receptor 3 is induced by and mediates antiviral activity against rhinovirus infection of human bronchial epithelial cells. J. Virol. 2005; 79: 12273-9.
32. Burgess JK, Oliver BG, Poniris MH, et al. A phosphodiesterase 4 inhibitor inhibits matrix protein deposition in airways in vitro. J. Allergy Clin. Immunol. 2006; 118: 649-57.
33. Hallgren O, Nihlberg K, Dahlback M, et al. Altered fibroblast proteoglycan production in COPD. Respir. Res. 2010; 11: 55.
34. Roche WR, Beasley R, Williams JH, et al. Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1989; 1: 520-4.
35. Leigh R, Oyelusi W, Wiehler S, et al. Human rhinovirus infection enhances airway epithelial cell production of growth factors involved in airway remodeling. J. Allergy Clin. Immunol. 2008; 121: 1238-45.e4.
36. Tacon CE, Wiehler S, Holden NS, et al. Human rhinovirus infection upregulates MMP-9 production in airway epithelial cells via NF-{kappa}B. Am. J. Respir. Cell Mol. Biol. 2010; 43: 201-9.
37. Proud D, Turner RB, Winther B, et al. Gene expression profiles during in vivo human rhinovirus infection: insights into the host response. Am. J. Respir. Crit. Care Med. 2008; 178: 962-8.
38. Konomi H, Hayashi T, Nakayasu K, et al. Localization of type V collagen and type IV collagen in human cornea, lung, and skin. Immunohistochemical evidence by anti-collagen antibodies characterized by immunoelectroblotting. Am. J. Pathol. 1984; 116: 417-26.
39. Delacoux F, Fichard A, Geourjon C, et al. Molecular features of the collagen V heparin binding site. J. Biol. Chem. 1998; 273: 15069-76.
40. Bobadilla JL, Love RB, Jankowska-Gan E, et al. Th-17, monokines, collagen type V, and primary graft dysfunction in lung transplantation. Am. J. Respir. Crit. Care Med. 2008; 177: 660-8.
41. Braun RK, Martin A, Shah S, et al. Inhibition of bleomycin-induced pulmonary fibrosis through pre-treatment with collagen type V. J. Heart Lung Transplant. 2010; 29: 873-80.
42. Berendsen AD, Bronckers AL, Smit TH, et al. Collagen type V enhances matrix contraction by human periodontal ligament fibroblasts seeded in three-dimensional collagen gels. Matrix Biol. 2006; 25: 515-22.
43. Yamashita K, Imaizumi T, Taima K, et al. Polyinosinic-polycytidylic acid induces the expression of GRO-alpha in BEAS-2B cells. Inflammation 2005; 29: 17-21.
44. Kelly MM, Leigh R, Bonniaud P, et al. Epithelial expression of profibrotic mediators in a model of allergen-induced airway remodeling. Am. J. Respir. Cell Mol. Biol. 2005; 32: 99-107.
45. Johnson PR, Burgess JK, Ge Q, et al. Connective tissue growth factor induces extracellular matrix in asthmatic airway smooth muscle. Am. J. Respir. Crit. Care Med. 2006; 173: 32-41.
46. Krenn BM, Holzer B, Gaudernak E, et al. Inhibition of polyprotein processing and RNA replication of human rhinovirus by pyrrolidine dithiocarbamate involves metal ions. J. Virol. 2005; 79: 13892-9.
47. Fraenkel DJ, Bardin PG, Sanderson G, et al. Lower airways inflammation during rhinovirus colds in normal and in asthmatic subjects. Am. J. Respir. Crit. Care Med. 1995; 151: 879-86.
48. Grunberg K, Smits HH, Timmers MC, et al. Experimental rhinovirus 16 infection. Effects on cell differentials and soluble markers in sputum in asthmatic subjects. Am. J. Respir. Crit. Care Med. 1997; 156: 609-16.
49. De Silva D, Dagher H, Ghildyal R, et al. Vascular endothelial growth factor induction by rhinovirus infection. J. Med. Virol. 2006; 78: 666-72.
50. Ghildyal R, Dagher H, Donninger H, et al. Rhinovirus infects primary human airway fibroblasts and induces a neutrophil chemokine and a permeability factor. J. Med. Virol. 2005; 75: 608-15.
51. Houck KA, Leung DW, Rowland AM, et al. Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms. J. Biol. Chem. 1992; 267: 26031-7.
52. Lee S, Jilani SM, Nikolova GV, et al. Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors. J. Cell Biol. 2005; 169: 681-91.
53. Hutchings H, Ortega N, Plouet J,. Extracellular matrix-bound vascular endothelial growth factor promotes endothelial cell adhesion, migration, and survival through integrin ligation. FASEB J. 2003; 17: 1520-2.
54. Ingber DE,. Cellular tensegrity: defining new rules of biological design that govern the cytoskeleton. J. Cell Sci. 1993; 104: 613-27.
55. Parameswaran K, Radford K, Zuo J, et al. Extracellular matrix regulates human airway smooth muscle cell migration. Eur. Respir. J. 2004; 24: 545-51.
56. Turner RB, Hendley JO, Gwaltney JM Jr,. Shedding of infected ciliated epithelial cells in rhinovirus colds. J. Infect. Dis. 1982; 145: 849-53.