18F-FDG uptake and calcifications in the thoracic aorta on positron emission tomography/computed tomography examinations: Frequency and stability on serial scans

Journal of Thoracic Imaging

Volumn 26, Issue 1, 2011, Pages 54-62

  Meirelles, Gustavo Souza Portes ^a   Gonen, Mithat ^b   Strauss, Harry William ^b  

^a FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

18F FDG; atherosclerosis; calcium; computed tomography; positron emission tomography

Indexed keywords

FLUORODEOXYGLUCOSE F 18; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ADULT; AGED; ARTICLE; BLOOD VESSEL CALCIFICATION; CANCER CHEMOTHERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CARDIOVASCULAR RISK; COMPUTER ASSISTED EMISSION TOMOGRAPHY; DIABETES MELLITUS; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; IMAGE ANALYSIS; IMAGE RECONSTRUCTION; MAJOR CLINICAL STUDY; MALE; RETROSPECTIVE STUDY; THORACIC AORTA; ATHEROSCLEROTIC PLAQUE; DRUG STABILITY; METABOLISM; METHODOLOGY; MIDDLE AGED; NEOPLASM; OBSERVER VARIATION; POSITRON EMISSION TOMOGRAPHY; REPRODUCIBILITY; RISK FACTOR; SCINTISCANNING;

ADULT; AGED; AGED, 80 AND OVER; AORTA, THORACIC; DRUG STABILITY; FEMALE; FLUORODEOXYGLUCOSE F18; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; OBSERVER VARIATION; PLAQUE, ATHEROSCLEROTIC; POSITRON-EMISSION TOMOGRAPHY; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; RISK FACTORS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 79551538936     PISSN: 08835993     EISSN: None     Source Type: Journal    
DOI: 10.1097/RTI.0b013e3181d9c9f9     Document Type: Article

References (38)

1. Libby P. The vascular biology of atherosclerosis. In: Libby P, Bonow RO, Mann DL, et al, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 8th ed. Philadelphia: Saunders Elsevier; 2007:987-1003.
2. Pitsavos CE, Aggeli KI, Barbetseas JD, et al. Effects of pravastatin on thoracic aortic atherosclerosis in patients with heterozygous familial hypercholesterolemia. Am J Cardiol. 1998;82:1484-1488.
3. Dunphy MP, Freiman A, Larson SM, et al. Association of vascular 18F-FDG uptake with vascular calcification. J Nucl Med. 2005;46:1278-1284.
4. Rudd JH, Myers KS, Bansilal S, et al. (18) Fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: implications for atherosclerosis therapy trials. J Am Coll Cardiol. 2007;50:892-896.
5. Ben-Haim S, Kupzov E, Tamir A, et al. Changing patterns of abnormal vascular wall F-18 fluorodeoxyglucose uptake on follow-up PET/CT studies. J Nucl Cardiol. 2006;13:791-800.
6. Sipahi I, Tuzcu EM, Schoenhagen P, et al. Paradoxical increase in lumen size during progression of coronary atherosclerosis: observations from the REVERSAL trial. Atherosclerosis. 2006;189:229-235.
7. Glagov S, Zarins C, Giddens DP, et al. Hemodynamics and atherosclerosis. Insights and perspectives gained from studies of human arteries. Arch Pathol Lab Med. 1988;112:1018-1031.
8. Kolodgie FD, Virmani R, Burke AP, et al. Pathologic assessment of the vulnerable human coronary plaque. Heart. 2004;90:1385-1391.
9. Schillinger M, Exner M, Mlekusch W, et al. Inflammation and carotid artery-risk for atherosclerosis study (ICARAS). Circulation. 2005;111:2203-2209.
10. Virmani R, Burke AP, Farb A, et al. Pathology of the vulnerable plaque. J Am Coll Cardiol. 2006;47(8 suppl): C13-C18.
11. Fleiner M, Kummer M, Mirlacher M, et al. Arterial neovascularization and inflammation in vulnerable patients: early and late signs of symptomatic atherosclerosis. Circulation. 2004;110:2843-2850.
12. Love C, Tomas MB, Tronco GG, et al. FDG PET of infection and inflammation. Radiographics. 2005;25:1357-1368.
13. Ogawa M, Ishino S, Mukai T, et al. (18) F-FDG accumulation in atherosclerotic plaques: immunohistochemical and PET imaging study. J Nucl Med. 2004;45:1245-1250.
14. Rudd JH, Warburton EA, Fryer TD, et al. Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography. Circulation. 2002;105:2708-2711.
15. Tawakol A, Migrino RQ, Hoffmann U, et al. Noninvasive in vivo measurement of vascular inflammation with F-18 fluorodeoxyglucose positron emission tomography. J Nucl Cardiol. 2005;12:294-301.
16. Fowler JS, Ding YS, Volkow ND. Radiotracers for positron emission tomography imaging. Semin Nucl Med. 2003;33:14-27.
17. Yun M, Jang S, Cucchiara A, et al. 18F FDG uptake in the large arteries: a correlation study with the atherogenic risk factors. Semin Nucl Med. 2002;32:70-76.
18. Yun M, Yeh D, Araujo LI, et al. F-18 FDG uptake in the large arteries: a new observation. Clin Nucl Med. 2001;26:314-319.
19. Tatsumi M, Cohade C, Nakamoto Y, et al. Fluorodeoxyglucose uptake in the aortic wall at PET/CT: possible finding for active atherosclerosis. Radiology. 2003;229:831-837.
20. Kaim AH, Weber B, Kurrer MO, et al. Autoradiographic quantification of 18F-FDG uptake in experimental soft-tissue abscesses in rats. Radiology. 2002;223:446-451.
21. Kubota R, Kubota K, Yamada S, et al. Microautoradiographic study for the differentiation of intratumoral macrophages, granulation tissues and cancer cells by the dynamics of fluorine-18-fluorodeoxyglucose uptake. J Nucl Med. 1994;35:104-112.
22. Walter MA, Melzer RA, Schindler C, et al. The value of [18F]FDG-PET in the diagnosis of large-vessel vasculitis and the assessment of activity and extent of disease. Eur J Nucl Med Mol Imaging. 2005;32:674-681.
23. Maschauer S, Prante O, Hoffmann M, et al. Characterization of 18F-FDG uptake in human endothelial cells in vitro. J Nucl Med. 2004;45:455-460.
24. Achenbach S, Daniel W. Computed tomography of the heart. In: Libby P, Bonow RO, Mann DL, et al, eds. Braunwald's Heart Disease a Textbook of Cardiovascular Medicine. 8th ed. Philadelphia: Saunders Elsevier; 2007:415-438.
25. Sangiorgi G, Rumberger JA, Severson A, et al. Arterial calcification and not lumen stenosis is highly correlated with atherosclerotic plaque burden in humans: a histologic study of 723 coronary artery segments using nondecalcifying methodology. J Am Coll Cardiol. 1998;31:126-133.
26. Ben-Haim S, Kupzov E, Tamir A, et al. Evaluation of 18F-FDG uptake and arterial wall calcifications using 18F-FDG PET/CT. J Nucl Med. 2004;45:1816-1821.
27. Agatston AS, Janowitz WR, Hildner FJ, et al. Quantification of coronary artery calcium using ultrafast computed tomography. J Am Coll Cardiol. 1990;15:827-832.
28. Belhocine T, Blockmans D, Hustinx R, et al. Imaging of large vessel vasculitis with (18) FDG PET: illusion or reality? A critical review of the literature data. Eur J Nucl Med Mol Imaging. 2003;30:1305-1313.
29. Brodmann M, Passath A, Aigner R, et al. F18-FDG-PET as a helpful tool in the diagnosis of giant cell arthritis. Rheumatology (Oxford). 2003;42:1264-1266.
30. Keidar Z, Engel A, Nitecki S, et al. PET/CT using 2-deoxy-2-[18F]fluoro- D-glucose for the evaluation of suspected infected vascular graft. Mol Imaging Biol. 2003;5:23-25.
31. Bengel FM. Vascular FDG uptake: further steps toward clinical acceptance. J Nucl Cardiol. 2008;15:154-156.
32. Dunphy MP, Schoder H, Strauss HW. Radionuclide techniques for identifying vulnerable plaque. J Nucl Med. 2007;48:1753-1755.
33. Keyes JW Jr. SUV: standard uptake or silly useless value? J Nucl Med. 1995;36:1836-1839.
34. Schwartz CJ, Valente AJ, Sprague EA, et al. Atherosclerosis as an inflammatory process. The roles of the monocytemacrophage. Ann N Y Acad Sci. 1985;454:115-120.
35. Akhurst T, Kates TJ, Mazumdar M, et al. Recent chemotherapy reduces the sensitivity of [18F]fluorodeoxyglucose positron emission tomography in the detection of colorectal metastases. J Clin Oncol. 2005;23:8713-8716.
36. Yao M, Smith RB, Graham MM, et al. The role of FDG PET in management of neck metastasis from head-and-neck cancer after definitive radiation treatment. Int J Radiat Oncol Biol Phys. 2005;63:991-999.
37. Trion A, van der Laarse A. Vascular smooth muscle cells and calcification in atherosclerosis. Am Heart J. 2004;147:808-814.
38. Nehmeh SA, Erdi YE, Pan T, et al. Four-dimensional (4D) PET/CT imaging of the thorax. Med Phys. 2004;31:3179-3186.