Synthesis and characterization of 2-aryl-4-(2-hydroxyetiyl)-2-morpholinol hydrochloride

Hunan Daxue Xuebao/Journal of Hunan University Natural Sciences

Volumn 31, Issue 4, 2004, Pages 11-14

  Hu, Ai Xi ^a   Wu, Hong Yan ^a   Chen, Xue Wei ^a   Zhou, Peng ^a  

^a HUNAN UNIVERSITY   (China)

Author keywords

2 aryl 4 (2 hydroxyethyl) 2 morpholinol; 2 aryl 4 (2 hydroxyethyl) 2 morpholinol hydrochloride; Characterization; Synthesis

Indexed keywords

CHARACTERIZATION; HYDROCHLORIC ACID; NAPHTHALENE; SYNTHESIS (CHEMICAL);

DIETHANOLAMINE; HYDROCHLORIDE SALT;

PHARMACOKINETICS;

EID: 7944238919     PISSN: 10002472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. KELLEY J L, MUSSO D L, BOSWELL G E, et al. (2S,3S,5R)-2-(3,5-difluorophenyl)-3,5-dimethyl-2-morpholinol: A Novel Antidepressant Agent and Selective Inhibitor of Norepinephrine Uptake [J]. J Med Chem, 1981, 18: 347-349.
2. ASCHER J A, JOSEPH J A, SUSAN L C M, et al. Pharmaceutically active morpholinol [P]. US: 2003 0332643, 2003 [CA 2003,138,147756]
3. KELLEY J L ,MUSSO D L, BOSWELL G E. Heterocyclic pharmaceutical compounds and use [P]. US: 5104870, 1992.
4. MEYER D R, WEINTRAUB P M. 2-Aryl-2H 1,4-tetrahydrooxazines [J]. J Heterocycl Chem, 1981, 18: 451-453.
5. HU A X, XIAO X R, CHEN K, et al. Synthesis of 2-Aryl-2-morpholinol [J]. Chin J Org Chem, 2004, 24: 924-927.
6. HU A X, HE L M, SHI W G, et al. Synthesis of α-Bromo-4-Substituted-Phenone [J]. Fine Chemicals, 2004, 21: 235-237.