Granulocyte-colony stimulating factor enhanced the recruitment of bone marrow cells into the heart: Time course evaluation of phenotypic differentiation in the doxorubicin-induced cardiomyopathic model

Japanese Journal of Thoracic and Cardiovascular Surgery

Volumn 52, Issue 10, 2004, Pages 451-455

  Hisashi, Yosuke ^a   Tomita, Shinji ^a   Nakatani, Takeshi ^a   Fukuhara, Shinya ^a   Yutani, Chikao ^a   Kitamura, Soichiro ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Bone marrow cells; Doxorubicin induced cardiomyopathy; Granulocyte colony stimulating factor; Migration; Phenotypic change

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CONNEXIN 43; DOXORUBICIN; GRANULOCYTE COLONY STIMULATING FACTOR; GREEN FLUORESCENT PROTEIN; KI 67 ANTIGEN; SODIUM CHLORIDE; TROPONIN I; VON WILLEBRAND FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BONE MARROW TRANSPLANTATION; CARDIOMYOPATHY; CONFERENCE PAPER; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; EVALUATION; HEART MUSCLE CELL; IMMUNOHISTOCHEMISTRY; IRRADIATION; MALE; MOUSE; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; TRANSGENIC MOUSE;

EID: 7944230301     PISSN: 13444964     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11748-004-0138-4     Document Type: Conference Paper

References (9)

1. Beltrami AP, Urbanek K, Kajstura J, Yan SM, Finato N, Bussani R, et al. Evidence that human cardiac myocytes divide after myocardial infarction. N Engl J Med 2001; 344: 1750-7.
2. Orlic D, Kajstura J, Chimenti S, Limana F, Jakoniuk I, Quaini F, et al. Mobilized bone marrow cells repair the infarcted heart, improving function and survival. Proc Natl Acad Sci USA 2001; 98: 10344-9.
3. Fukuhara S, Tomita S, Ohtsu Y, Ishida M, Yutani C, Kitamura S, et al. G-CSF promoted bone marrow cells to migrate into infarcted heart and differentiate into cardiomyocytes (abstracts). Circulation 2002; Supple II No. 1870: 376.
4. Suzuki K, Murtuza B, Suzuki N, Smolenski RT, Yacoub MH. Intracoronary infusion of skeletal myoblasts improves cardiac function in doxorubicin-induced heart failure (abstracts). Circulation 2001; 104 (12 Suppl 1): I213-7.
5. Kawakami N, Sakane N, Nishizawa F, Iwao M, Fukada SI, Tsujikawa K, et al. Green fluorescent protein-transgenic mice: Immune functions and their application to studies of lymphocyte development. Immunol Lett 1999; 70: 165-71.
6. Vitali E, Colombo T, Fratto P, Russo C, Bruschi G, Frigerio M. Surgical therapy in advanced heart failure. Am J Cardiol 2003; 91: 88F-94F.
7. Chen FY, Cohn LH. The surgical treatment of heart failure. A new frontier: Nontransplant surgical alternatives in heart failure. Cardiol Rev 2002; 10: 326-33.
8. Tomita S, Nakatani T, Fukuhara S, Morisaki T, Yutani C, Kitamura S. Bone marrow stromal cells contract synchronously with cardiomyocytes in a coculture system. Jpn J Thorac Cardiovasc Surg 2002; 50: 321-4.
9. Fukuhara S, Tomita S, Yamashiro S, Morisaki T, Yutani C, Kitamura S, et al. Direct cell-cell interaction of cardiomyocytes is key for bone marrow stromal cells to go into cardiac lineage in vitro. J Thorac Cardiovasc Surg 2003; 125: 1470-80.